Research Output

2018

Structural visualization of RNA polymerase III transcription machineries

Han, Y., Yan, C., Fishbain, S., Ivanov, I. & He, Y., Dec 1 2018, In : Cell Discovery. 4, 1, 40.

Research output: Contribution to journalArticle

8 Scopus citations
20 Scopus citations

Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein in complex with an amino-terminal peptide of the phosphoprotein

Aggarwal, M., Leser, G. P., Kors, C. A. & Lamb, R. A., Mar 1 2018, In : Journal of virology. 92, 5, e01304-17.

Research output: Contribution to journalArticle

13 Scopus citations

Survey of fertility preservation options available to patients with cancer around the globe

Rashedi, A. S., De Roo, S. F., Ataman, L. M., Edmonds, M. E., Silva, A. A., Scarella, A., Horbaczewska, A., Anazodo, A., Arvas, A., De Carvalho, B. R., Sartorio, C., Beerendonk, C. C. M., Diaz-Garcia, C., Suh, C. S., Melo, C., Andersen, C. Y., Motta, E., Greenblatt, E. M., Van Moer, E., Zand, E. & 43 others, Reis, F. M., Sánchez, F., Terrado, G., Rodrigues, J. K., De Meneses e Silva, J. M., Smitz, J., Medrano, J., Lee, J. R., Winkler-Crepaz, K., Smith, K., Melo e Silva, L. H. F., Wildt, L., Salama, M., Del Mar Andrés, M., Bourlon, M. T., Vega, M., Chehin, M. B., De Vos, M., Khrouf, M., Suzuki, N., Azmy, O., Fontoura, P., Campos-Junior, P. H. A., Mallmann, P., Azambuja, R., Marinho, R. M., Anderson, R. A., Jach, R., Antunes, R. A., Mitchell, R., Fathi, R., Adiga, S. K., Takae, S., Kim, S. H., Romero, S., Grieco, S. C., Shaulov, T., Furui, T., Almeida-Santos, T., Nelen, W., Jayasinghe, Y., Sugishita, Y. & Woodruff, T. K., Mar 1 2018, In : Journal of Global Oncology. 2018, 4

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Survey of third-party parenting options associated with fertility preservation available to patients with cancer around the globe

Rashedi, A. S., De Roo, S. F., Ataman, L. M., Edmonds, M. E., Silva, A. A., Scarella, A., Horbaczewska, A., Anazodo, A., Arvas, A., De Carvalho, B. R., Sartorio, C., Beerendonk, C. C. M., Diaz-Garcia, C., Suh, C. S., Melo, C., Andersen, C. Y., Motta, E., Greenblatt, E. M., Van Moer, E., Zand, E. & 43 others, Reis, F. M., Sánchez, F., Terrado, G., Rodrigues, J. K., De Meneses e Silva, J. M., Smitz, J., Medrano, J., Lee, J. R., Winkler-Crepaz, K., Smith, K., Melo e Silva, L. H. F., Wildt, L., Salama, M., Del Mar Andrés, M., Bourlon, M. T., Vega, M., Chehin, M. B., De Vos, M., Khrouf, M., Suzuki, N., Azmy, O., Fontoura, P., Campos-Junior, P. H. A., Mallmann, P., Azambuja, R., Marinho, R. M., Anderson, R. A., Jach, R., Antunes, R. A., Mitchell, R., Fathi, R., Adiga, S. K., Takae, S., Kim, S. H., Romero, S., Grieco, S. C., Shaulov, T., Furui, T., Almeida-Santos, T., Nelen, W., Jayasinghe, Y., Sugishita, Y. & Woodruff, T. K., Mar 1 2018, In : Journal of Global Oncology. 2018, 4

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Taxonomy of the order Mononegavirales: update 2018

Amarasinghe, G. K., Aréchiga Ceballos, N. G., Banyard, A. C., Basler, C. F., Bavari, S., Bennett, A. J., Blasdell, K. R., Briese, T., Bukreyev, A., Caì, Y., Calisher, C. H., Campos Lawson, C., Chandran, K., Chapman, C. A., Chiu, C. Y., Choi, K. S., Collins, P. L., Dietzgen, R. G., Dolja, V. V., Dolnik, O. & 71 others, Domier, L. L., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Echevarría, J. E., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freuling, C. M., Ghedin, E., Goldberg, T. L., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kityo, R., Kobinger, G. P., Kondō, H., Koonin, E. V., Krupovic, M., Kurath, G., Lamb, R. A., Lee, B., Leroy, E. M., Maes, P., Maisner, A., Marston, D. A., Mor, S. K., Müller, T., Mühlberger, E., Ramírez, V. M. N., Netesov, S. V., Ng, T. F. F., Nowotny, N., Palacios, G., Patterson, J. L., Pawęska, J. T., Payne, S. L., Prieto, K., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Siddell, S., Smither, S. J., Song, Q., Song, T., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Thomazelli, L. M., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Vázquez-Morón, S., Verdugo, C., Volchkov, V. E., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Wellehan, J. F. X., Wiley, M. R., Whitfield, A. E., Wolf, Y. I., Yè, G., Zhāng, Y. Z. & Kuhn, J. H., Aug 1 2018, In : Archives of Virology. 163, 8, p. 2283-2294 12 p.

Research output: Contribution to journalArticle

81 Scopus citations

The biosynthesis of methanobactin

Kenney, G. E., Dassama, L. M. K., Pandelia, M. E., Gizzi, A. S., Martinie, R. J., Gao, P., DeHart, C. J., Schachner, L. F., Skinner, O. S., Ro, S. Y., Zhu, X., Sadek, M., Thomas, P. M., Almo, S. C., Bollinger, J. M., Krebs, C., Kelleher, N. L. & Rosenzweig, A. C., Mar 23 2018, In : Science. 359, 6382, p. 1411-1416 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

The cyclic phosphodiesterase CNP and RNA cyclase RtcA fine-tune noncanonical XBP1 splicing during ER stress

Unlu, I., Lu, Y. & Wang, X., Jan 1 2018, In : Journal of Biological Chemistry. 293, 50, p. 19365-19376 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

The National Physicians Cooperative: Transforming fertility management in the cancer setting and beyond

Smith, B. M., Duncan, F. E., Ataman, L., Smith, K., Quinn, G. P., Chang, R. J., Finlayson, C., Orwig, K., Valli-Pulaski, H., Moravek, M. B., Zelinski, M. B., Irene Su, H., Vitek, W., Smith, J. F., Jeruss, J. S., Gracia, C., Coutifaris, C., Shah, D., Nahata, L., Gomez-Lobo, V. & 37 others, Appiah, L. C., Brannigan, R. E., Gillis, V., Gradishar, W., Javed, A., Rhoton-Vlasak, A. S., Kondapalli, L. A., Neuber, E., Ginsberg, J. P., Muller, C. H., Hirshfeld-Cytron, J., Kutteh, W. H., Lindheim, S. R., Cherven, B., Meacham, L. R., Rao, P., Torno, L., Sender, L. S., Vadaparampil, S. T., Skiles, J. L., Schafer-Kalkhoff, T., Frias, O. J., Byrne, J., Westphal, L. M., Schust, D. J., Klosky, J. L., McCracken, K. A., Ting, A., Khan, Z., Granberg, C., Lockart, B., Scoccia, B., Laronda, M. M., Mersereau, J. E., Marsh, C., Pavone, M. E. & Woodruff, T. K., Dec 2018, In : Future Oncology. 14, 29, p. 3059-3072 14 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

The role of mitochondria in anchoring dynein to the cell cortex extends beyond clustering the anchor protein

Schmit, H. L., Kraft, L. M., Lee-Smith, C. F. & Lackner, L. L., Jun 3 2018, In : Cell Cycle. 17, 11, p. 1345-1357 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

The unique biomineralization transcriptome and proteome of Lytechinus variegatus teeth

Alvares, K., DeHart, C. J., Thomas, P. M., Kelleher, N. L. & Veis, A., Nov 8 2018, In : Connective tissue research. 59, p. 20-29 10 p.

Research output: Contribution to journalArticle

The use of a virtual journal club to promote cross-cultural learning in the reproductive sciences

Duncan, F. E., Romar, R., Gadea, J., Kimelman, D., Wallach, H. D., Woodruff, T. K. & Jiménez-Movilla, M., 2018, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics.

Research output: Contribution to journalArticle

The Value of Activated Ion Electron Transfer Dissociation for High-Throughput Top-Down Characterization of Intact Proteins

Riley, N. M., Sikora, J. W., Seckler, H. S., Greer, J. B., Fellers, R. T., Leduc, R. D., Westphall, M. S., Thomas, P. M., Kelleher, N. L. & Coon, J. J., Jul 17 2018, In : Analytical Chemistry. 90, 14, p. 8553-8560 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

The Voyage Out: Endocrine Discoveries

Woodruff, T. K., Dec 1 2018, In : Endocrinology. 159, 12, p. 3908-3909 2 p.

Research output: Contribution to journalEditorial

Top-down characterization of endogenous protein complexes with native proteomics

Skinner, O. S., Haverland, N. A., Fornelli, L., Melani, R. D., Do Vale, L. H. F., Seckler, H. S., Doubleday, P. F., Schachner, L. F., Srzentić, K., Kelleher, N. L. & Compton, P. D., Jan 1 2018, In : Nature Chemical Biology. 14, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Top-down proteomics: Where we are, where we are going?

Fornelli, L., Toby, T. K., Schachner, L. F., Doubleday, P. F., Srzentić, K., DeHart, C. J. & Kelleher, N. L., Mar 20 2018, In : Journal of Proteomics. 175, p. 3-4 2 p.

Research output: Contribution to journalEditorial

17 Scopus citations

Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms between Mouse Strains

Davis, R. G., Park, H. M., Kim, K., Greer, J. B., Fellers, R. T., Leduc, R. D., Romanova, E. V., Rubakhin, S. S., Zombeck, J. A., Wu, C., Yau, P. M., Gao, P., Van Nispen, A. J., Patrie, S. M., Thomas, P. M., Sweedler, J. V., Rhodes, J. S. & Kelleher, N. L., Mar 20 2018, In : Analytical Chemistry. 90, 6, p. 3802-3810 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Total Synthesis of Tambromycin Enabled by Indole C-H Functionalization

Miley, G. P., Rote, J. C., Silverman, R. B., Kelleher, N. L. & Thomson, R. J., Apr 20 2018, In : Organic Letters. 20, 8, p. 2369-2373 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Transcriptional and chromatin regulation in interferon and innate antiviral gene expression

Au-Yeung, N. & Horvath, C. M., Dec 2018, In : Cytokine and Growth Factor Reviews. 44, p. 11-17 7 p.

Research output: Contribution to journalReview article

7 Scopus citations

Tweets and Transformative Technologies: Enabling Our Endocrine Future

Woodruff, T. K., Mar 1 2018, In : Endocrinology. 159, 3, p. 1417-1418 2 p.

Research output: Contribution to journalEditorial

2 Scopus citations

β-Glucocerebrosidase Modulators Promote Dimerization of β-Glucocerebrosidase and Reveal an Allosteric Binding Site

Zheng, J., Chen, L., Skinner, O. S., Ysselstein, D., Remis, J., Lansbury, P., Skerlj, R., Mrosek, M., Heunisch, U., Krapp, S., Charrow, J., Schwake, M., Kelleher, N. L., Silverman, R. B. & Krainc, D., May 9 2018, In : Journal of the American Chemical Society. 140, 18, p. 5914-5924 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

A biochemical sulfur delivery service

Rosenzweig, A. C., Oct 20 2017, In : Science. 358, 6361, p. 307-308 2 p.

Research output: Contribution to journalComment/debate

A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice

Laronda, M. M., Rutz, A. L., Xiao, S., Whelan, K. A., Duncan, F. E., Roth, E. W., Woodruff, T. K. & Shah, R. N., May 16 2017, In : Nature communications. 8, 15261.

Research output: Contribution to journalArticle

160 Scopus citations

A comparison of nucleosome organization in Drosophila cell lines

Martin, R. L., Maiorano, J., Beitel, G. J., Marko, J. F., McVicker, G. & Fondufe-Mittendorf, Y. N., Jun 2017, In : PloS one. 12, 6, e0178590.

Research output: Contribution to journalArticle

A cryptic tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation

Morgan, M. A. J., Rickels, R. A., Collings, C. K., He, X., Cao, K., Herz, H. M., Cozzolino, K. A., Abshiru, N. A., Marshall, S. A., Rendleman, E. J., Sze, C. C., Piunti, A., Kelleher, N. L., Savas, J. N. & Shilatifard, A., Oct 1 2017, In : Genes and Development. 31, 19, p. 2003-2014 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for animal nociception

Arenas, O. M., Zaharieva, E. E., Para, A., Vásquez-Doorman, C., Petersen, C. P. & Gallio, M., Dec 1 2017, In : Nature neuroscience. 20, 12, p. 1686-1693 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer

Fornelli, L., Durbin, K. R., Fellers, R. T., Early, B. P., Greer, J. B., LeDuc, R. D., Compton, P. D. & Kelleher, N. L., Feb 3 2017, In : Journal of Proteome Research. 16, 2, p. 609-618 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
8 Scopus citations
16 Scopus citations

A recessive genetic screen for components of the RNA interference pathway performed in mouse embryonic stem cells

Trombly, M. I. & Wang, X., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc, p. 111-129 19 p. (Methods in Molecular Biology; vol. 1622).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins

Bridge, K. S., Shah, K. M., Li, Y., Foxler, D. E., Wong, S. C. K., Miller, D. C., Davidson, K. M., Foster, J. G., Rose, R., Hodgkinson, M. R., Ribeiro, P. S., Aboobaker, A. A., Yashiro, K., Wang, X., Graves, P. R., Plevin, M. J., Lagos, D. & Sharp, T. V., Jul 5 2017, In : Cell reports. 20, 1, p. 173-187 15 p.

Research output: Contribution to journalArticle

21 Scopus citations

A scalable platform to identify fungal secondary metabolites and their gene clusters

Clevenger, K. D., Bok, J. W., Ye, R., Miley, G. P., Verdan, M. H., Velk, T., Chen, C., Yang, K. H., Robey, M. T., Gao, P., Lamprecht, M., Thomas, P. M., Islam, M. N., Palmer, J. M., Wu, C. C., Keller, N. P. & Kelleher, N. L., Aug 1 2017, In : Nature Chemical Biology. 13, 8, p. 895-901 7 p.

Research output: Contribution to journalArticle

56 Scopus citations

A synthetic biology approach to probing nucleosome symmetry

Ichikawa, Y., Connelly, C. F., Appleboim, A., Miller, T. C. R., Jacobi, H., Abshiru, N. A., Chou, H. J., Chen, Y., Sharma, U., Zheng, Y., Thomas, P. M., Chen, H. V., Bajaj, V., Müller, C. W., Kelleher, N. L., Friedman, N., Bolon, D. N. A., Rando, O. J. & Kaufman, P. D., Sep 12 2017, In : eLife. 6, e28836.

Research output: Contribution to journalArticle

4 Scopus citations

A tale of two methane monooxygenases

Ross, M. O. & Rosenzweig, A. C., Apr 1 2017, In : Journal of Biological Inorganic Chemistry. 22, 2-3, p. 307-319 13 p.

Research output: Contribution to journalReview article

51 Scopus citations

Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics

García-González, A. P., Ritter, A. D., Shrestha, S., Andersen, E. C., Yilmaz, L. S. & Walhout, A. J. M., Apr 20 2017, In : Cell. 169, 3, p. 431-441.e8

Research output: Contribution to journalArticle

76 Scopus citations

Bioinformatics analysis of top-down mass spectrometry data with proSight lite

Dehart, C. J., Fellers, R. T., Fornelli, L., Kelleher, N. L. & Thomas, P. M., 2017, Methods in Molecular Biology. Humana Press Inc., p. 381-394 14 p. (Methods in Molecular Biology; vol. 1558).

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations

Caenorhabditis elegans oocytes detect meiotic errors in the absence of canonical end-on kinetochore attachments

Davis-Roca, A. C., Muscat, C. C. & Wignall, S. M., May 1 2017, In : Journal of Cell Biology. 216, 5, p. 1243-1253 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cell Surface Proteomics of N-Linked Glycoproteins for Typing of Human Lymphocytes

Haverland, N. A., Waas, M., Ntai, I., Keppel, T., Gundry, R. L. & Kelleher, N. L., Oct 2017, In : Proteomics. 17, 19, 1700156.

Research output: Contribution to journalArticle

4 Scopus citations

CeNDR, the Caenorhabditis elegans natural diversity resource

Cook, D. E., Zdraljevic, S., Roberts, J. P. & Andersen, E. C., Jan 1 2017, In : Nucleic acids research. 45, D1, p. D650-D657

Research output: Contribution to journalArticle

57 Scopus citations

Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools

Mandacaru, S. C., do Vale, L. H. F., Vahidi, S., Xiao, Y., Skinner, O. S., Ricart, C. A. O., Kelleher, N. L., De Sousa, M. V. & Konermann, L., Mar 21 2017, In : Biochemistry. 56, 11, p. 1645-1655 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Chromatin and lamin a determine two different mechanical response regimes of the cell nucleus

Stephens, A. D., Banigan, E. J., Adam, S. A., Goldman, R. D. & Marko, J. F., Jul 7 2017, In : Molecular biology of the cell. 28, 14, p. 1984-1996 13 p.

Research output: Contribution to journalArticle

85 Scopus citations

Chromatographic efficiency and selectivity in top-down proteomics of histones

Zhou, Y., Zhang, X., Fornelli, L., Compton, P. D., Kelleher, N. & Wirth, M. J., Feb 15 2017, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1044-1045, p. 47-53 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring

Zha, L., Jiang, Y., Henke, M. T., Wilson, M. R., Wang, J. X., Kelleher, N. L. & Balskus, E. P., Oct 1 2017, In : Nature Chemical Biology. 13, 10, p. 1063-1065 3 p.

Research output: Contribution to journalArticle

25 Scopus citations

Concentration dependent chromatin states induced by the bicoid morphogen gradient

Hannon, C. E., Blythe, S. A. & Wieschaus, E. F., Sep 11 2017, In : eLife. 6, e28275.

Research output: Contribution to journalArticle

19 Scopus citations

Considering sex as a biological variable in preclinical research

Miller, L. R., Marks, C., Becker, J. B., Hurn, P. D., Chen, W. J., Woodruff, T., McCarthy, M. M., Sohrabji, F., Schiebinger, L., Lee Wetherington, C., Makris, S., Arnold, A. P., Einstein, G., Miller, V. M., Sandberg, K., Maier, S., Cornelison, T. L. & Clayton, J. A., Jan 2017, In : FASEB Journal. 31, 1, p. 29-34 6 p.

Research output: Contribution to journalArticle

92 Scopus citations

Correlations of genotype with climate parameters suggest Caenorhabditis elegans niche adaptations

Evans, K. S., Zhao, Y., Brady, S. C., Long, L., McGrath, P. T. & Andersen, E. C., 2017, In : G3: Genes, Genomes, Genetics. 7, 1, p. 289-298 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Corrigendum: The 4D nucleome project (Nature (2017) 549 (219-226) DOI: 10.1038/nature23884)

4D Nucleome Network, Dec 14 2017, In : Nature. 552, 7684, p. 278 1 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Counteracting Ascarosides Act through Distinct Neurons to Determine the Sexual Identity of C. elegans Pheromones

Aprison, E. Z. & Ruvinsky, I., Sep 11 2017, In : Current Biology. 27, 17, p. 2589-2599.e3

Research output: Contribution to journalArticle

10 Scopus citations

CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue

Bao, X., Siprashvili, Z., Zarnegar, B. J., Shenoy, R. M., Rios, E. J., Nady, N., Qu, K., Mah, A., Webster, D. E., Rubin, A. J., Wozniak, G. G., Tao, S., Wysocka, J. & Khavari, P. A., Oct 23 2017, In : Developmental Cell. 43, 2, p. 227-239.e5

Research output: Contribution to journalArticle

16 Scopus citations