Research Output

2017

Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring

Zha, L., Jiang, Y., Henke, M. T., Wilson, M. R., Wang, J. X., Kelleher, N. L. & Balskus, E. P., Oct 1 2017, In : Nature Chemical Biology. 13, 10, p. 1063-1065 3 p.

Research output: Contribution to journalArticle

25 Scopus citations

Concentration dependent chromatin states induced by the bicoid morphogen gradient

Hannon, C. E., Blythe, S. A. & Wieschaus, E. F., Sep 11 2017, In : eLife. 6, e28275.

Research output: Contribution to journalArticle

20 Scopus citations

Considering sex as a biological variable in preclinical research

Miller, L. R., Marks, C., Becker, J. B., Hurn, P. D., Chen, W. J., Woodruff, T., McCarthy, M. M., Sohrabji, F., Schiebinger, L., Lee Wetherington, C., Makris, S., Arnold, A. P., Einstein, G., Miller, V. M., Sandberg, K., Maier, S., Cornelison, T. L. & Clayton, J. A., Jan 2017, In : FASEB Journal. 31, 1, p. 29-34 6 p.

Research output: Contribution to journalArticle

93 Scopus citations

Correlations of genotype with climate parameters suggest Caenorhabditis elegans niche adaptations

Evans, K. S., Zhao, Y., Brady, S. C., Long, L., McGrath, P. T. & Andersen, E. C., 2017, In : G3: Genes, Genomes, Genetics. 7, 1, p. 289-298 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Corrigendum: The 4D nucleome project (Nature (2017) 549 (219-226) DOI: 10.1038/nature23884)

4D Nucleome Network, Dec 14 2017, In : Nature. 552, 7684, p. 278 1 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Counteracting Ascarosides Act through Distinct Neurons to Determine the Sexual Identity of C. elegans Pheromones

Aprison, E. Z. & Ruvinsky, I., Sep 11 2017, In : Current Biology. 27, 17, p. 2589-2599.e3

Research output: Contribution to journalArticle

10 Scopus citations

CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue

Bao, X., Siprashvili, Z., Zarnegar, B. J., Shenoy, R. M., Rios, E. J., Nady, N., Qu, K., Mah, A., Webster, D. E., Rubin, A. J., Wozniak, G. G., Tao, S., Wysocka, J. & Khavari, P. A., Oct 23 2017, In : Developmental Cell. 43, 2, p. 227-239.e5

Research output: Contribution to journalArticle

16 Scopus citations

Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry

Haverland, N. A., Skinner, O. S., Fellers, R. T., Tariq, A. A., Early, B. P., LeDuc, R. D., Fornelli, L., Compton, P. D. & Kelleher, N. L., Jun 1 2017, In : Journal of the American Society for Mass Spectrometry. 28, 6, p. 1203-1215 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain

Wildburger, N. C., Esparza, T. J., Leduc, R. D., Fellers, R. T., Thomas, P. M., Cairns, N. J., Kelleher, N. L., Bateman, R. J. & Brody, D. L., Dec 1 2017, In : Scientific reports. 7, 1, 9520.

Research output: Contribution to journalArticle

40 Scopus citations

Dose-dependent transduction of hedgehog relies on phosphorylation-based feedback between the G-protein-coupled receptor smoothened and the kinase fused

Sanial, M., Bécam, I., Hofmann, L., Behague, J., Argüelles, C., Gourhand, V., Bruzzone, L., Holmgren, R. A. & Plessis, A., May 15 2017, In : Development (Cambridge). 144, 10, p. 1841-1850 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Doxorubicin has dose-dependent toxicity on mouse ovarian follicle development, hormone secretion, and oocyte maturation

Xiao, S., Zhang, J., Liu, M., Iwahata, H., Rogers, H. B. & Woodruff, T. K., 2017, In : Toxicological Sciences. 157, 2, p. 320-329 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Draft genome sequences of three β-lactam-catabolizing soil Proteobacteria

Crofts, T. S., Wang, B., Spivak, A., Gianoulis, T. A., Forsberg, K. J., Gibson, M. K., Johnsky, L. A., Broomall, S. M., Rosenzweig, C. N., Skowronski, E. W., Gibbons, H. S., Sommer, M. O. A. & Dantasa, G., Aug 1 2017, In : Genome Announcements. 5, 32, e00653-17.

Research output: Contribution to journalArticle

2 Scopus citations

Editorial overview: Virus structure and functions

Jardetzky, T., Kuhn, R. & Lamb, R., Jun 2017, In : Current Opinion in Virology. 24, p. ix

Research output: Contribution to journalEditorial

Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance

Tung, K. S. K., Harakal, J., Qiao, H., Rival, C., Li, J. C. H., Paul, A. G. A., Wheeler, K., Pramoonjago, P., Grafer, C. M., Sun, W., Sampson, R. D., Wong, E. W. P., Reddi, P. P., Deshmukh, U. S., Hardy, D. M., Tang, H., Cheng, C. Y. & Goldberg, E., Mar 1 2017, In : Journal of Clinical Investigation. 127, 3, p. 1046-1060 15 p.

Research output: Contribution to journalArticle

31 Scopus citations

Engineering of a calcium-ion binding site into the RC-LH1-PufX complex of Rhodobacter sphaeroides to enable ion-dependent spectral red-shifting

Swainsbury, D. J. K., Martin, E. C., Vasilev, C., Parkes-Loach, P. S., Loach, P. A. & Neil Hunter, C., Nov 2017, In : Biochimica et Biophysica Acta - Bioenergetics. 1858, 11, p. 927-938 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Epigenetic transcriptional memory

D’Urso, A. & Brickner, J. H., Jun 1 2017, In : Current Genetics. 63, 3, p. 435-439 5 p.

Research output: Contribution to journalReview article

45 Scopus citations

Epigenetic transcriptional memory of GAL genes depends on growth in glucose and the tup1 transcription factor in saccharomyces cerevisiae

Sood, V., Cajigas, I., D’Urso, A., Light, W. H. & Brickner, J. H., 2017, In : Genetics. 206, 4, p. 1895-1907 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Erratum: Widespread Proteome Remodeling and Aggregation in Aging C. elegans (Cell (2015) 161(4) (919–932) (S0092867415003207)(10.1016/j.cell.2015.03.032)

Walther, D. M., Kasturi, P., Zheng, M., Pinkert, S., Vecchi, G., Ciryam, P., Morimoto, R. I., Dobson, C. M., Vendruscolo, M., Mann, M. & Hartl, F. U., Feb 23 2017, In : Cell. 168, 5, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Ethical, moral and other aspects related to fertility preservation in cancer patients

de Carvalho, B. R., Kliemchen, J. & Woodruff, T. K., 2017, In : Jornal Brasileiro de Reproducao Assistida. 21, 1, p. 45-48 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Expansion for the Brachylophosaurus canadensis Collagen i Sequence and Additional Evidence of the Preservation of Cretaceous Protein

Schroeter, E. R., Dehart, C. J., Cleland, T. P., Zheng, W., Thomas, P. M., Kelleher, N. L., Bern, M. & Schweitzer, M. H., Feb 3 2017, In : Journal of Proteome Research. 16, 2, p. 920-932 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

Facilitated dissociation of transcription factors from single DNA binding sites

Kamar, R. I., Banigan, E. J., Erbas, A., Giuntoli, R. D., De La Cruz, M. O., Johnson, R. C. & Marko, J. F., Apr 18 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 16, p. E3251-E3257

Research output: Contribution to journalArticle

23 Scopus citations

Fertility Lost-Fertility Found: Narratives from the Leading Edge of Oncofertility

Woodruff, T. K., 2017, In : Narrative inquiry in bioethics. 7, 2, p. 147-150 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genetic and epigenetic control of the spatial organization of the genome

Brickner, J., Feb 1 2017, In : Molecular biology of the cell. 28, 3, p. 364-369 6 p.

Research output: Contribution to journalReview article

6 Scopus citations

Genetic and Epigenetic Strategies Potentiate Gal4 Activation to Enhance Fitness in Recently Diverged Yeast Species

Sood, V. & Brickner, J. H., Dec 4 2017, In : Current Biology. 27, 23, p. 3591-3602.e3

Research output: Contribution to journalArticle

3 Scopus citations

Genome-wide Mapping of the Nucleosome Landscape by Micrococcal Nuclease and Chemical Mapping

Voong, L. N., Xi, L., Wang, J. P. & Wang, X., Aug 2017, In : Trends in Genetics. 33, 8, p. 495-507 13 p.

Research output: Contribution to journalReview article

9 Scopus citations

Global oncofertility index-data gap slows progress

de Roo, S. F., Rashedi, A. S., Beerendonk, C. C. M., Anazodo, A., de Man, A. M., Nelen, W. L. D. M. & Woodruff, T. K., 2017, In : Biology of reproduction. 96, 6, p. 1124-1128 5 p., iox051.

Research output: Contribution to journalComment/debate

6 Scopus citations

High-Throughput Analysis of Intact Human Proteins Using UVPD and HCD on an Orbitrap Mass Spectrometer

Cleland, T. P., Dehart, C. J., Fellers, R. T., Vannispen, A. J., Greer, J. B., LeDuc, R. D., Parker, W. R., Thomas, P. M., Kelleher, N. L. & Brodbelt, J. S., May 5 2017, In : Journal of Proteome Research. 16, 5, p. 2072-2079 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability

Rickels, R., Herz, H. M., Sze, C. C., Cao, K., Morgan, M. A., Collings, C. K., Gause, M., Takahashi, Y. H., Wang, L., Rendleman, E. J., Marshall, S. A., Krueger, A., Bartom, E. T., Piunti, A., Smith, E. R., Abshiru, N. A., Kelleher, N. L., Dorsett, D. & Shilatifard, A., Nov 1 2017, In : Nature Genetics. 49, 11, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells

Jayakanthan, S., Braiterman, L. T., Hasan, N. M., Unger, V. M. & Lutsenko, S., Nov 17 2017, In : Journal of Biological Chemistry. 292, 46, p. 18760-18774 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

ICTV virus taxonomy profile: Pneumoviridae

ICTV Report Consortium, Dec 2017, In : Journal of General Virology. 98, 12, p. 2912-2913 2 p., 000959.

Research output: Contribution to journalArticle

59 Scopus citations

Identification and Characterization of Human Proteoforms by Top-Down LC-21 Tesla FT-ICR Mass Spectrometry

Anderson, L. C., DeHart, C. J., Kaiser, N. K., Fellers, R. T., Smith, D. F., Greer, J. B., Leduc, R. D., Blakney, G. T., Thomas, P. M., Kelleher, N. L. & Hendrickson, C. L., Feb 3 2017, In : Journal of Proteome Research. 16, 2, p. 1087-1096 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration

Bonar, N. A. & Petersen, C. P., Mar 1 2017, In : Development (Cambridge). 144, 5, p. 784-794 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
13 Scopus citations
38 Scopus citations

In vivo properties of the disaggregase function of J-proteins and Hsc70 in Caenorhabditis elegans stress and aging

Kirstein, J., Arnsburg, K., Scior, A., Szlachcic, A., Guilbride, D. L., Morimoto, R. I., Bukau, B. & Nillegoda, N. B., Dec 2017, In : Aging Cell. 16, 6, p. 1414-1424 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Ivermectin susceptibility, sporontocidal effect, and inhibition of time to re-feed in the Amazonian malaria vector Anopheles darlingi

Kobylinski, K. C., Escobedo-Vargas, K. S., López-Sifuentes, V. M., Durand, S., Smith, E. S., Baldeviano, G. C., Gerbasi, R. V., Ballard, S. B., Stoops, C. A. & Vásquez, G. M., Nov 21 2017, In : Malaria journal. 16, 1, 474.

Research output: Contribution to journalArticle

7 Scopus citations

Lateral organization of influenza virus proteins in the budozone region of the plasma membrane

Leser, G. P. & Lamb, R. A., May 1 2017, In : Journal of virology. 91, 9, e02104-16.

Research output: Contribution to journalArticle

21 Scopus citations

Long-range correlations and fractal dynamics in C. elegans: Changes with aging and stress

Alves, L. G. A., Winter, P. B., Ferreira, L. N., Brielmann, R. M., Morimoto, R. I. & Amaral, L. A. N., Aug 29 2017, In : Physical Review E. 96, 2, 022417.

Research output: Contribution to journalArticle

8 Scopus citations

Measuring Signaling and RNA-Seq in the Same Cell Links Gene Expression to Dynamic Patterns of NF-κB Activation

Lane, K. M., Van Valen, D., DeFelice, M. M., Macklin, D. N., Kudo, T., Jaimovich, A., Carr, A., Meyer, T., Pe'er, D., Boutet, S. C. & Covert, M. W., Apr 26 2017, In : Cell Systems. 4, 4, p. 458-469.e5

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

Mechanics and Buckling of Biopolymeric Shells and Cell Nuclei

Banigan, E. J., Stephens, A. D. & Marko, J. F., Oct 17 2017, In : Biophysical Journal. 113, 8, p. 1654-1663 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Memory Is the Treasury and Guardian of All Things

D'Urso, A. & Brickner, J. H., Apr 6 2017, In : Molecular cell. 66, 1, p. 5-6 2 p.

Research output: Contribution to journalShort survey

Metal selectivity of a Cd-, Co-, and Zn-transporting P1B-type ATPase

Smith, A. T., Ross, M. O., Hoffman, B. M. & Rosenzweig, A. C., Jan 1 2017, In : Biochemistry. 56, 1, p. 85-95 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Methanobactins: From genome to function

Dassama, L. M. K., Kenney, G. E. & Rosenzweig, A. C., Jan 2017, In : Metallomics. 9, 1, p. 7-20 14 p.

Research output: Contribution to journalReview article

20 Scopus citations

Microprocessor Recruitment to Elongating RNA Polymerase II Is Required for Differential Expression of MicroRNAs

Church, V. A., Pressman, S., Isaji, M., Truscott, M., Cizmecioglu, N. T., Buratowski, S., Frolov, M. V. & Carthew, R. W., Sep 26 2017, In : Cell reports. 20, 13, p. 3123-3134 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

MicroRNA function in Drosophila melanogaster

Carthew, R. W., Agbu, P. & Giri, R., May 2017, In : Seminars in Cell and Developmental Biology. 65, p. 29-37 9 p.

Research output: Contribution to journalReview article

23 Scopus citations

MicroRNAs Make a Difference in Cardiovascular Robustness

Bakker, R. & Carthew, R. W., Mar 27 2017, In : Developmental Cell. 40, 6, p. 515-516 2 p.

Research output: Contribution to journalShort survey

3 Scopus citations

Mitochondria-driven assembly of a cortical anchor for mitochondria and dynein

Kraft, L. M. & Lackner, L. L., Oct 1 2017, In : Journal of Cell Biology. 216, 10, p. 3061-3071 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging

Labbadia, J., Brielmann, R. M., Neto, M. F., Lin, Y. F., Haynes, C. M. & Morimoto, R. I., Nov 7 2017, In : Cell reports. 21, 6, p. 1481-1494 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

Modulation of Protein Fragmentation Through Carbamylation of Primary Amines

Greer, S. M., Holden, D. D., Fellers, R., Kelleher, N. L. & Brodbelt, J. S., Aug 1 2017, In : Journal of the American Society for Mass Spectrometry. 28, 8, p. 1587-1599 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Molecular envelope and atomic model of an anti-terminated glyQS T-box regulator in complex with tRNAGly

Chetnani, B. & Mondragón, A., Jul 1 2017, In : Nucleic acids research. 45, 13, p. 8079-8090 12 p.

Research output: Contribution to journalArticle

5 Scopus citations