Research Output

A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity

Seckler, H. D. S., Fornelli, L., Mutharasan, R. K., Thaxton, C. S., Fellers, R., Daviglus, M., Sniderman, A., Rader, D., Kelleher, N. L., Lloyd-Jones, D. M., Compton, P. D. & Wilkins, J. T., Jun 1 2018, In : Journal of Proteome Research. 17, 6, p. 2156-2164 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

A targeted X-linked CMV-Cre line

Su, H., Mills, A. A., Wang, X. & Bradley, A., Mar 20 2002, In : Genesis. 32, 2, p. 187-188 2 p.

Research output: Contribution to journalArticle

39 Scopus citations

A threaded loop conformation adopted by a family of peptoid nonamers

Huang, K., Wu, C. W., Sanborn, T. J., Patch, J. A., Kirshenbaum, K., Zuckermann, R. N., Barron, A. E. & Radhakrishnan, I., Feb 8 2006, In : Journal of the American Chemical Society. 128, 5, p. 1733-1738 6 p.

Research output: Contribution to journalArticle

96 Scopus citations

A Three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome

Schrader, E. K., Harstad, K. G., Holmgren, R. A. & Matouschek, A., Nov 11 2011, In : Journal of Biological Chemistry. 286, 45, p. 39051-39058 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Atox1 contains positive residues that mediate membrane association and aid subsequent copper loading

Flores, A. G. & Unger, V. M., Sep 16 2013, In : Journal of Membrane Biology. 246, 12, p. 903-913 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

ATP/GTP hydrolysis is required for oxazole and thiazole biosynthesis in the peptide antibiotic microcin B17

Milne, J. C., Eliot, A. C., Kelleher, N. L. & Walsh, C. T., Sep 22 1998, In : Biochemistry. 37, 38, p. 13250-13261 12 p.

Research output: Contribution to journalArticle

49 Scopus citations

ATP-dependent interactions between Escherichia coli Min proteins and the phospholipid membrane in vitro

Lackner, L. L., Raskin, D. M. & De Boer, P. A. J., Feb 2003, In : Journal of bacteriology. 185, 3, p. 735-749 15 p.

Research output: Contribution to journalArticle

134 Scopus citations

ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2)

Bruns, A. M., Pollpeter, D., Hadizadeh, N., Myong, S., Marko, J. F. & Horvath, C. M., Jan 11 2013, In : Journal of Biological Chemistry. 288, 2, p. 938-946 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

A transcriptional signature of Alzheimer's disease is associated with a metastable subproteome at risk for aggregation

Ciryam, P., Kundra, R., Freer, R., Morimoto, R. I., Dobson, C. M. & Vendruscolo, M., Apr 26 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 17, p. 4753-4758 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

A Transgenic Analysis of Mouse Lactate Dehydrogenase c Promoter Activity in the Testis

Kroft, T. L., Li, S., Doglio, L. & Goldberg, E., Jan 1 2003, In : Journal of andrology. 24, 6, p. 843-852 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells

Buitrago-Delgado, E., Schock, E. N., Nordin, K. & LaBonne, C., Dec 15 2018, In : Developmental Biology. 444, 2, p. 50-61 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

ATTEMPTS TO LOCATE COMPLEMENTARITY‐DETERMINING RESIDUES IN THE VARIABLE POSITIONS OF LIGHT AND HEAVY CHAINS

Kabat, E. A. & Wu, T. T., Jan 1 1971, In : Annals of the New York Academy of Sciences. 190, 1, p. 382-393 12 p.

Research output: Contribution to journalArticle

127 Scopus citations
21 Scopus citations
151 Scopus citations

Attomole protein characterization by capillary electrophoresis-mass spectrometry

Valaskovic, G. A., Kelleher, N. L. & McLafferty, F. W., 1996, In : Science. 273, 5279, p. 1199-1202 4 p.

Research output: Contribution to journalArticle

324 Scopus citations

Attomole-Sensitivity Electrospray Source for Large-Molecule Mass Spectrometry

Valaskovic, G. A., Kelleher, N. L., Little, D. P., Aaserud, D. J. & McLafferty, F. W., 1995, In : Analytical Chemistry. 67, 20, p. 3802-3805 4 p.

Research output: Contribution to journalArticle

203 Scopus citations

Autocrine stimulation of nb2 cell proliferation by secreted, but not intracellular, prolactin

Davis, J. A. & Linzer, D. I. H., Aug 1988, In : Molecular Endocrinology. 2, 8, p. 740-746 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Autoinhibition of endophilin in solution via interdomain interactions

Vázquez, F. X., Unger, V. M. & Voth, G. A., Jan 22 2013, In : Biophysical Journal. 104, 2, p. 396-403 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Autophagy, Apoptosis, and the Influenza Virus M2 Protein

Rossman, J. S. & Lamb, R. A., Nov 22 2009, In : Cell Host and Microbe. 6, 4, p. 299-300 2 p.

Research output: Contribution to journalShort survey

47 Scopus citations

Autopilot: An online data acquisition control system for the enhanced high-throughput characterization of intact proteins

Durbin, K. R., Fellers, R. T., Ntai, I., Kelleher, N. L. & Compton, P. D., Feb 4 2014, In : Analytical Chemistry. 86, 3, p. 1485-1492 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Autoregulation of the Heat Shock Transcriptional Response

Shi, Y. D. & Morimoto, R. I., 1998, Handbook of Experimental Pharmacology, Vol. 136: Stress Proteins. Latchman, D. (ed.). Springer-Verlag, p. 225-242

Research output: Chapter in Book/Report/Conference proceedingChapter

A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology

Andersen, E. C., Bloom, J. S., Gerke, J. P. & Kruglyak, L., Feb 2014, In : PLoS genetics. 10, 2, e1004156.

Research output: Contribution to journalArticle

53 Scopus citations

A Wild C. Elegans Strain Has Enhanced Epithelial Immunity to a Natural Microsporidian Parasite

Balla, K. M., Andersen, E. C., Kruglyak, L. & Troemel, E. R., 2015, In : PLoS pathogens. 11, 2, e1004583.

Research output: Contribution to journalArticle

21 Scopus citations

A wound-induced Wnt expression program controls planarian regeneration polarity

Petersen, C. P. & Reddien, P. W., Oct 6 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 40, p. 17061-17066 6 p.

Research output: Contribution to journalArticle

150 Scopus citations

Baboon spermatozoa-zona pellucida binding assay

Mahony, M. C., Rice, K., Goldberg, E. & Doncel, G., Mar 1 2000, In : Contraception. 61, 3, p. 235-240 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Bacteria-induced uroplakin signaling mediates bladder response to infection

Thumbikat, P., Berry, R. E., Zhou, G., Billips, B. K., Yaggie, R. E., Zaichuk, T., Sun, T. T., Schaeffer, A. J. & Klumpp, D. J., May 2009, In : PLoS pathogens. 5, 5, e1000415.

Research output: Contribution to journalArticle

109 Scopus citations

Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics

García-González, A. P., Ritter, A. D., Shrestha, S., Andersen, E. C., Yilmaz, L. S. & Walhout, A. J. M., Apr 20 2017, In : Cell. 169, 3, p. 431-441.e8

Research output: Contribution to journalArticle

76 Scopus citations

Bacterial topoisomerase i and topoisomerase III relax supercoiled DNA via distinct pathways

Terekhova, K., Gunn, K. H., Marko, J. F. & Mondragón, A., Nov 2012, In : Nucleic acids research. 40, 20, p. 10432-10440 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release

Bimston, D., Song, J., Winchester, D., Takayama, S., Reed, J. C. & Morimoto, R. I., Dec 1 1998, In : EMBO Journal. 17, 23, p. 6871-6878 8 p.

Research output: Contribution to journalArticle

148 Scopus citations

Bag1 functions in vivo as a negative regulator of Hsp70 chaperone activity

Nollen, E. A. A., Brunsting, J. F., Song, J., Kampinga, H. H. & Morimoto, R. I., Feb 2000, In : Molecular and cellular biology. 20, 3, p. 1083-1088 6 p.

Research output: Contribution to journalArticle

107 Scopus citations

Bag1-Hsp 70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth

Song, J., Takeda, M. & Morimoto, R. I., Mar 20 2001, In : Nature Cell Biology. 3, 3, p. 276-282 7 p.

Research output: Contribution to journalArticle

216 Scopus citations

BAG-1 modulates the chaperone activity of Hsp70/Hsc70

Takayama, S., Bimston, D. N., Matsuzawa, S. I., Freeman, B. C., Aime-Sempe, C., Xie, Z., Morimoto, R. I. & Reed, J. C., Aug 15 1997, In : EMBO Journal. 16, 16, p. 4887-4896 10 p.

Research output: Contribution to journalArticle

409 Scopus citations

Balanced trade-offs between alternative strategies shape the response of C. elegans reproduction to chronic heat stress

Aprison, E. Z. & Ruvinsky, I., Aug 28 2014, In : PloS one. 9, 8, e105513.

Research output: Contribution to journalArticle

14 Scopus citations

Barriers and opportunities of oncofertility practice in nine developing countries and the emerging oncofertility professional engagement network

Salama, M., Ataman-Millhouse, L., Sobral, F., Terrado, G., Scarella, A., Bourlon, M. T., Adiga, S. K., Udupa, K. S., Mahajan, N., Patil, M., Venter, C., Demetriou, G., Quintana, R., Rodriguez, G., Quintana, T., Viale, L., Bonilla, Y. A. R., Noguera, J. A. R., Velásquez, J. C. V., Pineda, J. I. D. & 6 others, Aldecoa, M. D. C., Javed, M., Al Sufyan, H., Daniels, N., Ogunmokun, A. A. & Woodruff, T. K., 2018, In : Journal of Global Oncology. 2018, 4, 00180.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Barrier-to-autointegration factor (BAF) condenses DNA by looping

Skoko, D., Li, M., Huang, Y., Mizuuchi, M., Cai, M., Bradley, C. M., Pease, P. J., Xiao, B., Marko, J. F., Craigie, R. & Mizuuchi, K., Sep 29 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 39, p. 16610-16615 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Basis for structural diversity in homologous RNAs

Krasilnikov, A. S., Xiao, Y., Pan, T. & Mondragon, A., Oct 1 2004, In : Science. 306, 5693, p. 104-107 4 p.

Research output: Contribution to journalArticle

116 Scopus citations

Bend-Induced Twist Waves and the Structure of Nucleosomal DNA

Skoruppa, E., Nomidis, S. K., Marko, J. F. & Carlon, E., Aug 21 2018, In : Physical review letters. 121, 8, 088101.

Research output: Contribution to journalArticle

6 Scopus citations

Bending and Twisting Elasticity of DNA

Marko, J. F. & Siggia, E. D., 1996, Polymeric Materials Encyclopedia. Salamone, J. (ed.). Boca Raton, FL: CRC Press, p. 1915-21

Research output: Chapter in Book/Report/Conference proceedingChapter

Bending and Twisting Elasticity of DNA

Marko, J. F. & Siggia, E. D., Jul 1 1994, In : Macromolecules. 27, 4, p. 981-988 8 p.

Research output: Contribution to journalArticle

215 Scopus citations

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

Donnelly, D. P., Rawlins, C. M., DeHart, C. J., Fornelli, L., Schachner, L. F., Lin, Z., Lippens, J. L., Aluri, K. C., Sarin, R., Chen, B., Lantz, C., Jung, W., Johnson, K. R., Koller, A., Wolff, J. J., Campuzano, I. D. G., Auclair, J. R., Ivanov, A. R., Whitelegge, J. P., Paša-Tolić, L. & 8 others, Chamot-Rooke, J., Danis, P. O., Smith, L. M., Tsybin, Y. O., Loo, J. A., Ge, Y., Kelleher, N. L. & Agar, J. N., Jul 1 2019, In : Nature Methods. 16, 7, p. 587-594 8 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Bimolecular complementation of paramyxovirus fusion and hemagglutinin-neuraminidase proteins enhances fusion: Implications for the mechanism of fusion triggering

Connolly, S. A., Leser, G. P., Jardetzky, T. S. & Lamb, R. A., Nov 2009, In : Journal of virology. 83, 21, p. 10857-10868 12 p.

Research output: Contribution to journalArticle

74 Scopus citations

Binding of antibodies against antigenic domains of murine lactate dehydrogenase-C4 to human and mouse spermatozoa

Beyler, S. A., Wheat, T. E. & Goldberg, E., Jan 1 1985, In : Biology of Reproduction. 32, 5, p. 1201-1210 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Binding of antibody to LDH‐X by the mouse blastocyst

Bene, M. & Goldberg, E., Aug 1974, In : Journal of Experimental Zoology. 189, 2, p. 261-266 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Binding of Complementary Oligonucleotides to Free and Aminoacyl Transfer Ribonucleic Acid Synthetase Bound Transfer Ribonucleic Acid

Schimmel, P. R., Uhlenbeck, O. C., Dickson, L. A., Eldred, E. W. & Schreier, A. A., Feb 1 1972, In : Biochemistry. 11, 4, p. 642-646 5 p.

Research output: Contribution to journalArticle

43 Scopus citations

Binding of Copper(I) by the Wilson Disease Protein and Its Copper Chaperone

Wernimont, A. K., Yatsunyk, L. A. & Rosenzweig, A. C., Mar 26 2004, In : Journal of Biological Chemistry. 279, 13, p. 12269-12276 8 p.

Research output: Contribution to journalArticle

78 Scopus citations

Binding of misacylated tRNAs to the ribosomal a site

Dale, T. & Uhlenbeck, O. C., Nov 2005, In : RNA. 11, 11, p. 1610-1615 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Binding of polyomavirus large T antigen to the human hsp70 promoter is not required for trans activation

Kingston, R. E., Cowie, A., Morimoto, R. I. & Gwinn, K. A., 1986, In : Molecular and cellular biology. 6, 9, p. 3180-3190 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Binding of yeast tRNAphe anticodon arm to Escherichia coli 30 S ribosomes

Rose, S. J., Lowary, P. T. & Uhlenbeck, O. C., Jun 15 1983, In : Journal of Molecular Biology. 167, 1, p. 103-117 15 p.

Research output: Contribution to journalArticle

49 Scopus citations
10 Scopus citations

Biocatalysts for methane conversion: big progress on breaking a small substrate

Lawton, T. J. & Rosenzweig, A. C., Dec 1 2016, In : Current Opinion in Chemical Biology. 35, p. 142-149 8 p.

Research output: Contribution to journalReview article

9 Scopus citations