Research Output

Filter
Article
2013

Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase v by structural and functional studies

Rajan, R., Prasad, R., Taneja, B., Wilson, S. H. & Mondragón, A., Jan 1 2013, In : Nucleic acids research. 41, 1, p. 657-666 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Inhibitors of the Influenza A Virus M2 Proton Channel Discovered Using a High-Throughput Yeast Growth Restoration Assay

Balgi, A. D., Wang, J., Cheng, D. Y. H., Ma, C., Pfeifer, T. A., Shimizu, Y., Anderson, H. J., Pinto, L. H., Lamb, R. A., DeGrado, W. F. & Roberge, M., Feb 1 2013, In : PloS one. 8, 2, e55271.

Research output: Contribution to journalArticle

33 Scopus citations

Integration of multiple chromophores with native photosynthetic antennas to enhance solar energy capture and delivery

Harris, M. A., Parkes-Loach, P. S., Springer, J. W., Jiang, J., Martin, E. C., Qian, P., Jiao, J., Niedzwiedzki, D. M., Kirmaier, C., Olsen, J. D., Bocian, D. F., Holten, D., Hunter, C. N., Lindsey, J. S. & Loach, P. A., Aug 26 2013, In : Chemical Science. 4, 10, p. 3924-3933 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Interactions between Twist and other core epithelial-mesenchymal transition factors are controlled by GSK3-mediated phosphorylation

Lander, R., Nasr, T., Ochoa, S. D., Nordin, K., Prasad, M. S. & Labonne, C., Mar 11 2013, In : Nature communications. 4, 1542.

Research output: Contribution to journalArticle

43 Scopus citations

In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome

Ciryam, P., Morimoto, R. I., Vendruscolo, M., Dobson, C. M. & O'Brien, E. P., Jan 8 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 2, p. E132-E140

Research output: Contribution to journalArticle

51 Scopus citations

Large-scale top-down proteomics of the human proteome: Membrane proteins, mitochondria, and senescence

Catherman, A. D., Durbin, K. R., Ahl, D. R., Early, B. P., Fellers, R. T., Tran, J. C., Thomas, P. M. & Kelleher, N. L., Dec 1 2013, In : Molecular and Cellular Proteomics. 12, 12, p. 3465-3473 9 p.

Research output: Contribution to journalArticle

96 Scopus citations
54 Scopus citations

Metabolic perturbation of an essential pathway: Evaluation of a glycine precursor of coenzyme A

Rothmann, M., Kang, M., Villa, R., Ntai, I., La Clair, J. J., Kelleher, N. L., Chapman, E. & Burkart, M. D., Apr 24 2013, In : Journal of the American Chemical Society. 135, 16, p. 5962-5965 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

MicroRNA profiling of sendai virus-infected A549 cells identifies miR-203 as an interferon-inducible regulator of IFIT1/ISG56

Buggele, W. A. & Horvath, C. M., Aug 1 2013, In : Journal of virology. 87, 16, p. 9260-9270 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

MiR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor

Cassidy, J. J., Jha, A. R., Posadas, D. M., Giri, R., Venken, K. J. T., Ji, J., Jiang, H., Bellen, H. J., White, K. P. & Carthew, R. W., Dec 19 2013, In : Cell. 155, 7, p. 1556-1567 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability

Bose, S., Heath, C. M., Shah, P. A., Alayyoubi, M., Jardetzky, T. S. & Lamb, R. A., Dec 1 2013, In : Journal of virology. 87, 24, p. 13520-13531 12 p.

Research output: Contribution to journalArticle

37 Scopus citations

Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease

Gidalevitz, T., Wang, N., Deravaj, T., Alexander-Floyd, J. & Morimoto, R. I., Sep 30 2013, In : BMC Biology. 11, 100.

Research output: Contribution to journalArticle

22 Scopus citations

Neuronal Reprograming of Protein Homeostasis by Calcium-Dependent Regulation of the Heat Shock Response

Silva, M. C., Amaral, M. D. & Morimoto, R. I., Aug 2013, In : PLoS genetics. 9, 8, e1003711.

Research output: Contribution to journalArticle

13 Scopus citations
18 Scopus citations

Oncogene-induced cellular senescence elicits an anti-Warburg effect

Li, M., Durbin, K. R., Sweet, S. M. M., Tipton, J. D., Zheng, Y. & Kelleher, N. L., Sep 1 2013, In : Proteomics. 13, 17, p. 2585-2596 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Palette of lipophilic bioconjugatable bacteriochlorins for construction of biohybrid light-harvesting architectures

Reddy, K. R., Jiang, J., Krayer, M., Harris, M. A., Springer, J. W., Yang, E., Jiao, J., Niedzwiedzki, D. M., Pandithavidana, D., Parkes-Loach, P. S., Kirmaier, C., Loach, P. A., Bocian, D. F., Holten, D. & Lindsey, J. S., Apr 2 2013, In : Chemical Science. 4, 5, p. 2036-2053 18 p.

Research output: Contribution to journalArticle

37 Scopus citations

Posttranslational control of Cdc25 degradation terminates drosophila's early cell-cycle program

Di Talia, S., She, R., Blythe, S. A., Lu, X., Zhang, Q. F. & Wieschaus, E. F., Jan 21 2013, In : Current Biology. 23, 2, p. 127-132 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Protein-mediated transformation of lipid vesicles into tubular networks

Simunovic, M., Mim, C., Marlovits, T. C., Resch, G., Unger, V. M. & Voth, G. A., Aug 6 2013, In : Biophysical Journal. 105, 3, p. 711-719 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
20 Scopus citations

Quantitative peptidomics for discovery of circadian-related peptides from the rat suprachiasmatic nucleus

Lee, J. E., Zamdborg, L., Southey, B. R., Atkins, N., Mitchell, J. W., Li, M., Gillette, M. U., Kelleher, N. L. & Sweedler, J. V., Feb 1 2013, In : Journal of Proteome Research. 12, 2, p. 585-593 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Recent advances in studying mechanical properties of DNA

Vafabakhsh, R., Lee, K. S. & Ha, T., Dec 1 2013, In : Advances in Chemical Physics. 150, p. 169-186 18 p.

Research output: Contribution to journalArticle

1 Scopus citations

Regulation of organismal proteostasis by transcellular chaperone signaling

Van Oosten-Hawle, P., Porter, R. S. & Morimoto, R. I., Jun 6 2013, In : Cell. 153, 6, 1 p.

Research output: Contribution to journalArticle

107 Scopus citations

Regulation of Primitive Hematopoiesis by Class I Histone Deacetylases

Shah, R. R., Koniski, A., Shinde, M., Blythe, S. A., Fass, D. M., Haggarty, S. J., Palis, J. & Klein, P. S., Feb 1 2013, In : Developmental Dynamics. 242, 2, p. 108-121 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

Rehabilitation of faulty kinetic determinations and misassigned glycoside hydrolase family of retaining mechanism b-xylosidases

Jordan, D. B., Vermillion, K. E., Grigorescu, A. A. & Braker, J. D., Jan 1 2013, In : Archives of biochemistry and biophysics. 537, 2, p. 176-184 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Sinorhizobium meliloti Nia is a P1B-5-ATPase expressed in the nodule during plant symbiosis and is involved in Ni and Fe transport

Zielazinski, E. L., González-Guerrero, M., Subramanian, P., Stemmler, T. L., Argüello, J. M. & Rosenzweig, A. C., Dec 1 2013, In : Metallomics. 5, 12, p. 1614-1623 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Small RNA Profiling of Influenza A Virus-Infected Cells Identifies miR-449b as a Regulator of Histone Deacetylase 1 and Interferon Beta

Buggele, W. A., Krause, K. E. & Horvath, C. M., Sep 26 2013, In : PloS one. 8, 9, e76560.

Research output: Contribution to journalArticle

28 Scopus citations

Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest

Félix, M. A., Jovelin, R., Ferrari, C., Han, S., Cho, Y. R., Andersen, E. C., Cutter, A. D. & Braendle, C., 2013, In : BMC Evolutionary Biology. 13, 1, 10.

Research output: Contribution to journalArticle

38 Scopus citations

Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegans

Nussbaum-Krammer, C. I., Park, K. W., Li, L., Melki, R. & Morimoto, R. I., 2013, In : PLoS genetics. 9, 3, e1003351.

Research output: Contribution to journalArticle

34 Scopus citations

Structural basis for assembly of the MnIV/FeIII cofactor in the class ic ribonucleotide reductase from chlamydia trachomatis

Dassama, L. M. K., Krebs, C., Bollinger, J. M., Rosenzweig, A. C. & Boal, A. K., Sep 17 2013, In : Biochemistry. 52, 37, p. 6424-6436 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Structural studies of RNase P

Mondragon, A., May 1 2013, In : Annual Review of Biophysics. 42, 1, p. 537-557 21 p.

Research output: Contribution to journalArticle

35 Scopus citations

Structural visualization of key steps in human transcription initiation

He, Y., Fang, J., Taatjes, D. J. & Nogales, E., Mar 28 2013, In : Nature. 495, 7442, p. 481-486 6 p.

Research output: Contribution to journalArticle

162 Scopus citations

Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus

Wang, J., Wu, Y., Ma, C., Fiorin, G., Wang, J., Pinto, L. H., Lamb, R. A., Klein, M. L. & DeGrado, W. F., Jan 22 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 4, p. 1315-1320 6 p.

Research output: Contribution to journalArticle

141 Scopus citations

Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain

Welch, B. D., Yuan, P., Bose, S., Kors, C. A., Lamb, R. A. & Jardetzky, T. S., Aug 1 2013, In : PLoS pathogens. 9, 8, e1003534.

Research output: Contribution to journalArticle

46 Scopus citations

Studies of bacterial topoisomerases I and III at the single-molecule level

Terekhova, K., Marko, J. F. & Mondragó n, A., Apr 1 2013, In : Biochemical Society transactions. 41, 2, p. 571-575 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

The amphipathic helix of influenza a virus M2 protein is required for filamentous bud formation and scission of filamentous and spherical particles

Roberts, K. L., Leser, G. P., Ma, C. & Lamb, R. A., Sep 5 2013, In : Journal of virology. 87, 18, p. 9973-9982 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

The emergence of top-down proteomics in clinical research

Savaryn, J. P., Catherman, A. D., Thomas, P. M., Abecassis, M. M. & Kelleher, N. L., Jun 27 2013, In : Genome Medicine. 5, 6, 53.

Research output: Contribution to journalArticle

59 Scopus citations

The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer

Ezponda, T., Popovic, R., Shah, M. Y., Martinez-Garcia, E., Zheng, Y., Min, D. J., Will, C., Neri, A., Kelleher, N. L., Yu, J. & Licht, J. D., Jun 6 2013, In : Oncogene. 32, 23, p. 2882-2890 9 p.

Research output: Contribution to journalArticle

78 Scopus citations

The nascent polypeptide-associated complex is a key regulator of proteostasis

Kirstein-Miles, J., Scior, A., Deuerling, E. & Morimoto, R. I., May 15 2013, In : EMBO Journal. 32, 10, p. 1451-1468 18 p.

Research output: Contribution to journalArticle

85 Scopus citations

The relationship between long-range chromatin occupancy and polymerization of the drosophila ets family transcriptional repressor yan

Webber, J. L., Zhang, J., Cote, L., Vivekanand, P., Ni, X., Zhou, J., Nègre, N., Carthew, R. W., White, K. P. & Rebay, I., Apr 29 2013, In : Genetics. 193, 2, p. 633-649 17 p.

Research output: Contribution to journalArticle

22 Scopus citations

The SMC1-SMC3 cohesin heterodimer structures DNA through supercoiling-dependent loop formation

Sun, M., Nishino, T. & Marko, J. F., Jul 2013, In : Nucleic acids research. 41, 12, p. 6149-6160 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Top down proteomics of human membrane proteins from enriched mitochondrial fractions

Catherman, A. D., Li, M., Tran, J. C., Durbin, K. R., Compton, P. D., Early, B. P., Thomas, P. M. & Kelleher, N. L., Feb 5 2013, In : Analytical Chemistry. 85, 3, p. 1880-1888 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Towards an optimized inhibition of liver stage development assay (ILSDA) for Plasmodium falciparum

Zou, X., House, B. L., Zyzak, M. D., Richie, T. L. & Gerbasi, R. V., Nov 12 2013, In : Malaria journal. 12, 1, 394.

Research output: Contribution to journalArticle

17 Scopus citations

Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway

Au-Yeung, N., Mandhana, R. & Horvath, C. M., 2013, In : JAK-STAT. e23931 .

Research output: Contribution to journalArticle

TRNA residues evolved to promote translational accuracy

Shepotinovskaya, I. & Uhlenbeck, O. C., Apr 1 2013, In : RNA. 19, 4, p. 510-516 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Tubulogenesis

Iruela-Arispe, M. L. & Beitel, G. J., Jul 15 2013, In : Development (Cambridge). 140, 14, p. 2851-2855 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Understanding the role of amphipathic helices in N-bar domain driven membrane remodeling

Cui, H., Mim, C., Vázquez, F. X., Lyman, E., Unger, V. M. & Voth, G. A., Jan 22 2013, In : Biophysical Journal. 104, 2, p. 404-411 8 p.

Research output: Contribution to journalArticle

61 Scopus citations

Vps factors are required for efficient transcription elongation in budding yeast

Gaur, N. A., Hasek, J., Brickner, D. G., Qiu, H., Zhang, F., Wong, C. M., Malcova, I., Vasicova, P., Brickner, J. H. & Hinnebusch, A. G., 2013, In : Genetics. 193, 3, p. 829-851 23 p.

Research output: Contribution to journalArticle

14 Scopus citations

Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins

Ciryam, P., Tartaglia, G. G., Morimoto, R. I., Dobson, C. M. & Vendruscolo, M., Nov 7 2013, In : Cell reports. 5, 3, p. 781-790 10 p.

Research output: Contribution to journalArticle

123 Scopus citations

X-ray phase-contrast in vivo microtomography probes new aspects of Xenopus gastrulation

Moosmann, J., Ershov, A., Altapova, V., Baumbach, T., Prasad, M. S., LaBonne, C., Xiao, X., Kashef, J. & Hofmann, R., May 16 2013, In : Nature. 497, 7449, p. 374-377 4 p.

Research output: Contribution to journalArticle

58 Scopus citations
2012

A cell-based approach to the human proteome project

Kelleher, N. L., Oct 1 2012, In : Journal of the American Society for Mass Spectrometry. 23, 10, p. 1617-1624 8 p.

Research output: Contribution to journalArticle

35 Scopus citations