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2017

Chromatin and lamin a determine two different mechanical response regimes of the cell nucleus

Stephens, A. D., Banigan, E. J., Adam, S. A., Goldman, R. D. & Marko, J. F., Jul 7 2017, In : Molecular biology of the cell. 28, 14, p. 1984-1996 13 p.

Research output: Contribution to journalArticle

77 Scopus citations

Chromatographic efficiency and selectivity in top-down proteomics of histones

Zhou, Y., Zhang, X., Fornelli, L., Compton, P. D., Kelleher, N. & Wirth, M. J., Feb 15 2017, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1044-1045, p. 47-53 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring

Zha, L., Jiang, Y., Henke, M. T., Wilson, M. R., Wang, J. X., Kelleher, N. L. & Balskus, E. P., Oct 1 2017, In : Nature Chemical Biology. 13, 10, p. 1063-1065 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Concentration dependent chromatin states induced by the bicoid morphogen gradient

Hannon, C. E., Blythe, S. A. & Wieschaus, E. F., Sep 11 2017, In : eLife. 6, e28275.

Research output: Contribution to journalArticle

17 Scopus citations

Correlations of genotype with climate parameters suggest Caenorhabditis elegans niche adaptations

Evans, K. S., Zhao, Y., Brady, S. C., Long, L., McGrath, P. T. & Andersen, E. C., Jan 1 2017, In : G3: Genes, Genomes, Genetics. 7, 1, p. 289-298 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Counteracting Ascarosides Act through Distinct Neurons to Determine the Sexual Identity of C. elegans Pheromones

Aprison, E. Z. & Ruvinsky, I., Sep 11 2017, In : Current Biology. 27, 17, p. 2589-2599.e3

Research output: Contribution to journalArticle

9 Scopus citations

CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue

Bao, X., Siprashvili, Z., Zarnegar, B. J., Shenoy, R. M., Rios, E. J., Nady, N., Qu, K., Mah, A., Webster, D. E., Rubin, A. J., Wozniak, G. G., Tao, S., Wysocka, J. & Khavari, P. A., Oct 23 2017, In : Developmental Cell. 43, 2, p. 227-239.e5

Research output: Contribution to journalArticle

14 Scopus citations

Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry

Haverland, N. A., Skinner, O. S., Fellers, R. T., Tariq, A. A., Early, B. P., LeDuc, R. D., Fornelli, L., Compton, P. D. & Kelleher, N. L., Jun 1 2017, In : Journal of the American Society for Mass Spectrometry. 28, 6, p. 1203-1215 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain

Wildburger, N. C., Esparza, T. J., Leduc, R. D., Fellers, R. T., Thomas, P. M., Cairns, N. J., Kelleher, N. L., Bateman, R. J. & Brody, D. L., Dec 1 2017, In : Scientific reports. 7, 1, 9520.

Research output: Contribution to journalArticle

36 Scopus citations

Dose-dependent transduction of hedgehog relies on phosphorylation-based feedback between the G-protein-coupled receptor smoothened and the kinase fused

Sanial, M., Bécam, I., Hofmann, L., Behague, J., Argüelles, C., Gourhand, V., Bruzzone, L., Holmgren, R. A. & Plessis, A., May 15 2017, In : Development (Cambridge). 144, 10, p. 1841-1850 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Draft genome sequences of three β-lactam-catabolizing soil Proteobacteria

Crofts, T. S., Wang, B., Spivak, A., Gianoulis, T. A., Forsberg, K. J., Gibson, M. K., Johnsky, L. A., Broomall, S. M., Rosenzweig, C. N., Skowronski, E. W., Gibbons, H. S., Sommer, M. O. A. & Dantasa, G., Aug 1 2017, In : Genome Announcements. 5, 32, e00653-17.

Research output: Contribution to journalArticle

2 Scopus citations

Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance

Tung, K. S. K., Harakal, J., Qiao, H., Rival, C., Li, J. C. H., Paul, A. G. A., Wheeler, K., Pramoonjago, P., Grafer, C. M., Sun, W., Sampson, R. D., Wong, E. W. P., Reddi, P. P., Deshmukh, U. S., Hardy, D. M., Tang, H., Cheng, C. Y. & Goldberg, E., Mar 1 2017, In : Journal of Clinical Investigation. 127, 3, p. 1046-1060 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Engineering of a calcium-ion binding site into the RC-LH1-PufX complex of Rhodobacter sphaeroides to enable ion-dependent spectral red-shifting

Swainsbury, D. J. K., Martin, E. C., Vasilev, C., Parkes-Loach, P. S., Loach, P. A. & Neil Hunter, C., Nov 2017, In : Biochimica et Biophysica Acta - Bioenergetics. 1858, 11, p. 927-938 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Epigenetic transcriptional memory of GAL genes depends on growth in glucose and the tup1 transcription factor in saccharomyces cerevisiae

Sood, V., Cajigas, I., D’Urso, A., Light, W. H. & Brickner, J. H., Jan 1 2017, In : Genetics. 206, 4, p. 1895-1907 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Expansion for the Brachylophosaurus canadensis Collagen i Sequence and Additional Evidence of the Preservation of Cretaceous Protein

Schroeter, E. R., DeHart, C. J., Cleland, T. P., Zheng, W., Thomas, P. M., Kelleher, N. L., Bern, M. & Schweitzer, M. H., Feb 3 2017, In : Journal of Proteome Research. 16, 2, p. 920-932 13 p.

Research output: Contribution to journalArticle

28 Scopus citations

Facilitated dissociation of transcription factors from single DNA binding sites

Kamar, R. I., Banigan, E. J., Erbas, A., Giuntoli, R. D., De La Cruz, M. O., Johnson, R. C. & Marko, J. F., Apr 18 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 16, p. E3251-E3257

Research output: Contribution to journalArticle

23 Scopus citations

Genetic and Epigenetic Strategies Potentiate Gal4 Activation to Enhance Fitness in Recently Diverged Yeast Species

Sood, V. & Brickner, J. H., Dec 4 2017, In : Current Biology. 27, 23, p. 3591-3602.e3

Research output: Contribution to journalArticle

2 Scopus citations

High-Throughput Analysis of Intact Human Proteins Using UVPD and HCD on an Orbitrap Mass Spectrometer

Cleland, T. P., Dehart, C. J., Fellers, R. T., Vannispen, A. J., Greer, J. B., LeDuc, R. D., Parker, W. R., Thomas, P. M., Kelleher, N. L. & Brodbelt, J. S., May 5 2017, In : Journal of Proteome Research. 16, 5, p. 2072-2079 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability

Rickels, R., Herz, H. M., Sze, C. C., Cao, K., Morgan, M. A., Collings, C. K., Gause, M., Takahashi, Y. H., Wang, L., Rendleman, E. J., Marshall, S. A., Krueger, A., Bartom, E. T., Piunti, A., Smith, E. R., Abshiru, N. A., Kelleher, N. L., Dorsett, D. & Shilatifard, A., Nov 1 2017, In : Nature Genetics. 49, 11, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells

Jayakanthan, S., Braiterman, L. T., Hasan, N. M., Unger, V. M. & Lutsenko, S., Jan 1 2017, In : Journal of Biological Chemistry. 292, 46, p. 18760-18774 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

ICTV virus taxonomy profile: Pneumoviridae

ICTV Report Consortium, Dec 2017, In : Journal of General Virology. 98, 12, p. 2912-2913 2 p., 000959.

Research output: Contribution to journalArticle

53 Scopus citations

Identification and Characterization of Human Proteoforms by Top-Down LC-21 Tesla FT-ICR Mass Spectrometry

Anderson, L. C., DeHart, C. J., Kaiser, N. K., Fellers, R. T., Smith, D. F., Greer, J. B., Leduc, R. D., Blakney, G. T., Thomas, P. M., Kelleher, N. L. & Hendrickson, C. L., Feb 3 2017, In : Journal of Proteome Research. 16, 2, p. 1087-1096 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration

Bonar, N. A. & Petersen, C. P., Mar 1 2017, In : Development (Cambridge). 144, 5, p. 784-794 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
9 Scopus citations
33 Scopus citations

In vivo properties of the disaggregase function of J-proteins and Hsc70 in Caenorhabditis elegans stress and aging

Kirstein, J., Arnsburg, K., Scior, A., Szlachcic, A., Guilbride, D. L., Morimoto, R. I., Bukau, B. & Nillegoda, N. B., Dec 2017, In : Aging Cell. 16, 6, p. 1414-1424 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Ivermectin susceptibility, sporontocidal effect, and inhibition of time to re-feed in the Amazonian malaria vector Anopheles darlingi

Kobylinski, K. C., Escobedo-Vargas, K. S., López-Sifuentes, V. M., Durand, S., Smith, E. S., Baldeviano, G. C., Gerbasi, R. V., Ballard, S. B., Stoops, C. A. & Vásquez, G. M., Nov 21 2017, In : Malaria journal. 16, 1, 474.

Research output: Contribution to journalArticle

6 Scopus citations

Lateral organization of influenza virus proteins in the budozone region of the plasma membrane

Leser, G. P. & Lamb, R. A., May 1 2017, In : Journal of virology. 91, 9, e02104-16.

Research output: Contribution to journalArticle

19 Scopus citations

Long-range correlations and fractal dynamics in C. elegans: Changes with aging and stress

Alves, L. G. A., Winter, P. B., Ferreira, L. N., Brielmann, R. M., Morimoto, R. I. & Amaral, L. A. N., Aug 29 2017, In : Physical Review E. 96, 2, 022417.

Research output: Contribution to journalArticle

6 Scopus citations

Measuring Signaling and RNA-Seq in the Same Cell Links Gene Expression to Dynamic Patterns of NF-κB Activation

Lane, K. M., Van Valen, D., DeFelice, M. M., Macklin, D. N., Kudo, T., Jaimovich, A., Carr, A., Meyer, T., Pe'er, D., Boutet, S. C. & Covert, M. W., Apr 26 2017, In : Cell Systems. 4, 4, p. 458-469.e5

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Mechanics and Buckling of Biopolymeric Shells and Cell Nuclei

Banigan, E. J., Stephens, A. D. & Marko, J. F., Oct 17 2017, In : Biophysical Journal. 113, 8, p. 1654-1663 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Metal selectivity of a Cd-, Co-, and Zn-transporting P1B-type ATPase

Smith, A. T., Ross, M. O., Hoffman, B. M. & Rosenzweig, A. C., Jan 1 2017, In : Biochemistry. 56, 1, p. 85-95 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Microprocessor Recruitment to Elongating RNA Polymerase II Is Required for Differential Expression of MicroRNAs

Church, V. A., Pressman, S., Isaji, M., Truscott, M., Cizmecioglu, N. T., Buratowski, S., Frolov, M. V. & Carthew, R. W., Sep 26 2017, In : Cell reports. 20, 13, p. 3123-3134 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Mitochondria-driven assembly of a cortical anchor for mitochondria and dynein

Kraft, L. M. & Lackner, L. L., Oct 1 2017, In : Journal of Cell Biology. 216, 10, p. 3061-3071 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging

Labbadia, J., Brielmann, R. M., Neto, M. F., Lin, Y. F., Haynes, C. M. & Morimoto, R. I., Nov 7 2017, In : Cell reports. 21, 6, p. 1481-1494 14 p.

Research output: Contribution to journalArticle

34 Scopus citations

Modulation of Protein Fragmentation Through Carbamylation of Primary Amines

Greer, S. M., Holden, D. D., Fellers, R., Kelleher, N. L. & Brodbelt, J. S., Aug 1 2017, In : Journal of the American Society for Mass Spectrometry. 28, 8, p. 1587-1599 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Molecular envelope and atomic model of an anti-terminated glyQS T-box regulator in complex with tRNAGly

Chetnani, B. & Mondragón, A., Jul 1 2017, In : Nucleic acids research. 45, 13, p. 8079-8090 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

Misharin, A. V., Morales-Nebreda, L., Reyfman, P. A., Cuda, C. M., Walter, J. M., McQuattie-Pimentel, A. C., Chen, C. I., Anekalla, K. R., Joshi, N., Williams, K. J. N., Abdala-Valencia, H., Yacoub, T. J., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Gates, K., Lam, A. P., Nicholson, T. T., Homan, P. J., Soberanes, S. & 23 others, Dominguez, S., Morgan, V. K., Saber, R., Shaffer, A., Hinchcliff, M., Marshall, S. A., Bharat, A., Berdnikovs, S., Bhorade, S. M., Bartom, E. T., Morimoto, R. I., Balch, W. E., Sznajder, J. I., Chandel, N. S., Mutlu, G. M., Jain, M., Gottardi, C. J., Singer, B. D., Ridge, K. M., Bagheri, N., Shilatifard, A., Budinger, G. R. S. & Perlman, H., Aug 1 2017, In : Journal of Experimental Medicine. 214, 8, p. 2387-2404 18 p.

Research output: Contribution to journalArticle

185 Scopus citations

Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation

Wong, J. J. W., Young, T. A., Zhang, J., Liu, S., Leser, G. P., Komives, E. A., Lamb, R. A., Zhou, Z. H., Salafsky, J. & Jardetzky, T. S., Dec 1 2017, In : Nature communications. 8, 1, 781.

Research output: Contribution to journalArticle

11 Scopus citations

Native Electron Capture Dissociation Maps to Iron-Binding Channels in Horse Spleen Ferritin

Skinner, O. S., McAnally, M. O., Van Duyne, R. P., Schatz, G. C., Breuker, K., Compton, P. D. & Kelleher, N. L., Oct 17 2017, In : Analytical Chemistry. 89, 20, p. 10711-10716 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons

Zdraljevic, S., Strand, C., Seidel, H. S., Cook, D. E., Doench, J. G. & Andersen, E. C., Jul 2017, In : PLoS genetics. 13, 7, e1006891.

Research output: Contribution to journalArticle

13 Scopus citations

Natural Variation in the Distribution and Abundance of Transposable Elements Across the Caenorhabditis elegans Species

Laricchia, K. M., Zdraljevic, S., Cook, D. E. & Andersen, E. C., Sep 1 2017, In : Molecular biology and evolution. 34, 9, p. 2187-2202 16 p.

Research output: Contribution to journalArticle

13 Scopus citations

Nucleation of Multiple Buckled Structures in Intertwined DNA Double Helices

Brahmachari, S., Gunn, K. H., Giuntoli, R. D., Mondragón, A. & Marko, J. F., Oct 31 2017, In : Physical review letters. 119, 18, 188103.

Research output: Contribution to journalArticle

4 Scopus citations

Nup98 regulation of histone methylation promotes normal gene expression and may drive leukemogenesis

Sump, B. & Brickner, J. H., Nov 30 2017, In : Genes and Development. 31, 22, p. 2201-2203 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Oligomerization and ATP stimulate condensin-mediated DNA compaction

Keenholtz, R. A., Dhanaraman, T., Palou, R., Yu, J., D'amours, D. & Marko, J. F., Dec 1 2017, In : Scientific reports. 7, 1, 14279.

Research output: Contribution to journalArticle

16 Scopus citations

Out of the testis: Biological impacts of new genes

Nyberg, K. G. & Carthew, R. W., Sep 15 2017, In : Genes and Development. 31, 18, p. 1825-1826 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Possibility and challenges of conversion of current virus species names to Linnaean binomials

Postler, T. S., Clawson, A. N., Amarasinghe, G. K., Basler, C. F., Bavari, S., Benko, M., Blasdell, K. R., Briese, T., Buchmeier, M. J., Bukreyev, A., Calisher, C. H., Chandran, K., Charrel, R., Clegg, C. S., Collins, P. L., De La Torre, J. C., DeRisi, J. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R. & 52 others, Dye, J. M., Easton, A. J., Emonet, S., Formenty, P., Fouchier, R. A. M., Ghedin, E., Gonzalez, J. P., Harrach, B., Hewson, R., Horie, M., Jiāng, D., Kobinger, G., Kondo, H., Kropinski, A. M., Krupovic, M., Kurath, G., Lamb, R. A., Leroy, E. M., Lukashevich, I. S., Maisner, A., Mushegian, A. R., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Peters, C. J., Radoshitzky, S. R., Rima, B. K., Romanowski, V., Rubbenstroth, D., Sabanadzovic, S., Sanfaçon, H., Salvato, M. S., Schwemmle, M., Smither, S. J., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Volchkov, V. E., Wahl-Jensen, V., Walker, P. J., Wang, L. F., Varsani, A., Whitfield, A. E., Murilo Zerbini, F. & Kuhn, J. H., May 1 2017, In : Systematic Biology. 66, 3, p. 463-473 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Protein homeostasis of a metastable subproteome associated with Alzheimer's disease

Kundra, R., Ciryam, P., Morimoto, R. I., Dobson, C. M. & Vendruscolo, M., Jul 11 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 28, p. E5703-E5711

Research output: Contribution to journalArticle

28 Scopus citations

Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients

Toby, T. K., Abecassis, M., Kim, K., Thomas, P. M., Fellers, R. T., LeDuc, R. D., Kelleher, N. L., Demetris, J. & Levitsky, J., Sep 2017, In : American Journal of Transplantation. 17, 9, p. 2458-2467 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover

Mascarenhas, R., Le, H. V., Clevenger, K. D., Lehrer, H. J., Ringe, D., Kelleher, N. L., Silverman, R. B. & Liu, D., Sep 19 2017, In : Biochemistry. 56, 37, p. 4951-4961 11 p.

Research output: Contribution to journalArticle

4 Scopus citations