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2016

Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression

Helenius, I. T., Nair, A., Bittar, H. E. T., Sznajder, J. I., Sporn, P. H. S. & Beitel, G. J., Apr 1 2016, In : Journal of Biomolecular Screening. 21, 4, p. 363-371 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hexagonal Patterning of the Insect Compound Eye: Facet Area Variation, Defects, and Disorder

Kim, S., Cassidy, J. J., Yang, B., Carthew, R. W. & Hilgenfeldt, S., Dec 20 2016, In : Biophysical Journal. 111, 12, p. 2735-2746 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identification of drosophila Zfh2 as a mediator of hypercapnic immune regulation by a genome-wide RNA interference screen

Helenius, I. T., Haake, R. J., Kwon, Y. J., Hu, J. A., Krupinski, T., Marina Casalino-Matsuda, S., Sporn, P. H. S., Sznajder, J. I. & Beitel, G. J., Jan 15 2016, In : Journal of Immunology. 196, 2, p. 655-667 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins

Albert, S. S., Taylor, A. P., Luciano, A. A., Theodore, S. J., Matteo, D. P. & Lamb, R. A., Jul 5 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 27, p. E3844-E3851

Research output: Contribution to journalArticle

2 Scopus citations

Insights into Nucleosome Organization in Mouse Embryonic Stem Cells through Chemical Mapping

Voong, L. N., Xi, L., Sebeson, A. C., Xiong, B., Wang, J. & Wang, X., Dec 1 2016, In : Cell. 167, 6, p. 1555-1570.e15

Research output: Contribution to journalArticle

61 Scopus citations

Integrated bottom-up and top-down proteomics of patient-derived breast tumor xenografts

Ntai, I., LeDuc, R. D., Fellers, R. T., Erdmann-Gilmore, P., Davies, S. R., Rumsey, J., Early, B. P., Thomas, P. M., Li, S., Compton, P. D., Ellis, M. J. C., Ruggles, K. V., Fenyö, D., Boja, E. S., Rodriguez, H., Townsend, R. R. & Kelleher, N. L., Jan 2016, In : Molecular and Cellular Proteomics. 15, 1, p. 45-56 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis

Teng, X., Emmett, M. J., Lazar, M. A., Goldberg, E. & Rabinowitz, J. D., Sep 16 2016, In : ACS chemical biology. 11, 9, p. 2420-2427 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Male fertility and obesity: Are ghrelin, leptin and glucagon-like peptide-1 pharmacologically relevant?

Alves, M. G., Jesus, T. T., Sousa, M., Goldberg, E., Silva, B. M. & Oliveira, P. F., Feb 1 2016, In : Current Pharmaceutical Design. 22, 7, p. 783-791 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Mapping proteoforms and protein complexes from king cobra venom using both denaturing and native top-down proteomics

Melani, R. D., Skinner, O. S., Fornelli, L., Domont, G. B., Compton, P. D. & Kelleher, N. L., Jul 2016, In : Molecular and Cellular Proteomics. 15, 7, p. 2423-2434 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Mass spectrometry imaging and identification of peptides associated with cephalic ganglia regeneration in Schmidtea mediterranea

Ong, T. H., Romanova, E. V., Roberts-Galbraith, R. H., Yang, N., Zimmerman, T. A., Collins, J. J., Lee, J. E., Kelleher, N. L., Newmark, P. A. & Sweedler, J. V., Apr 8 2016, In : Journal of Biological Chemistry. 291, 15, p. 8109-8120 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Metabologenomics: Correlation of microbial gene clusters with metabolites drives discovery of a nonribosomal peptide with an unusual amino acid monomer

Goering, A. W., McClure, R. A., Doroghazi, J. R., Albright, J. C., Haverland, N. A., Zhang, Y., Ju, K. S., Thomson, R. J., Metcalf, W. W. & Kelleher, N. L., Feb 24 2016, In : ACS Central Science. 2, 2, p. 99-108 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Methane-Oxidizing Enzymes: An Upstream Problem in Biological Gas-to-Liquids Conversion

Lawton, T. J. & Rosenzweig, A. C., Aug 3 2016, In : Journal of the American Chemical Society. 138, 30, p. 9327-9340 14 p.

Research output: Contribution to journalArticle

54 Scopus citations

Methanobactin transport machinery

Dassama, L. M. K., Kenney, G. E., Ro, S. Y., Zielazinski, E. L. & Rosenzweig, A. C., Nov 15 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 46, p. 13027-13032 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Methanopyrus kandleri topoisomerase v contains three distinct AP lyase active sites in addition to the topoisomerase active site

Rajan, R., Osterman, A. & Mondragón, A., Feb 22 2016, In : Nucleic acids research. 44, 7, p. 3464-3474 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Modern mass spectrometry for synthetic biology and structure-based discovery of natural products

Henke, M. T. & Kelleher, N. L., Aug 2016, In : Natural product reports. 33, 8, p. 942-950 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mutagenesis of paramyxovirus hemagglutinin-neuraminidase membrane-proximal stalk region influences stability, receptor binding, and neuraminidase activity

Adu-Gyamfi, E., Kim, L. S., Jardetzky, T. S. & Lamb, R. A., Jan 1 2016, In : Journal of virology. 90, 17, p. 7778-7788 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mutation is a sufficient and robust predictor of genetic variation for mitotic spindle traits in Caenorhabditis elegans

Farhadifar, R., Ponciano, J. M., Andersen, E. C., Needleman, D. J. & Baer, C. F., Aug 2016, In : Genetics. 203, 4, p. 1859-1870 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Near-atomic resolution visualization of human transcription promoter opening

He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I. & Nogales, E., May 11 2016, In : Nature. 533, p. 359-365 7 p.

Research output: Contribution to journalArticle

123 Scopus citations

New Aspercryptins, Lipopeptide Natural Products, Revealed by HDAC Inhibition in Aspergillus nidulans

Henke, M. T., Soukup, A. A., Goering, A. W., McClure, R. A., Thomson, R. J., Keller, N. P. & Kelleher, N. L., Aug 19 2016, In : ACS chemical biology. 11, 8, p. 2117-2123 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Nucleation by rRNA dictates the precision of nucleolus assembly

Falahati, H., Pelham-Webb, B., Blythe, S. & Wieschaus, E., Feb 8 2016, In : Current Biology. 26, 3, p. 277-285 9 p.

Research output: Contribution to journalArticle

63 Scopus citations

Num1 anchors mitochondria to the plasma membrane via two domains with different lipid binding specificities

Ping, H. A., Kraft, L. M., Chen, W. T., Nilles, A. E. & Lackner, L. L., Jan 1 2016, In : Journal of Cell Biology. 213, 5, p. 513-524 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Printable enzyme-embedded materials for methane to methanol conversion

Blanchette, C. D., Knipe, J. M., Stolaroff, J. K., Deotte, J. R., Oakdale, J. S., Maiti, A., Lenhardt, J. M., Sirajuddin, S., Rosenzweig, A. C. & Baker, S. E., Jun 15 2016, In : Nature communications. 7, 11900.

Research output: Contribution to journalArticle

36 Scopus citations

Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa

Durbin, K. R., Fornelli, L., Fellers, R. T., Doubleday, P. F., Narita, M. & Kelleher, N. L., Mar 4 2016, In : Journal of Proteome Research. 15, 3, p. 976-982 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Role of transcription factor-mediated nucleosome disassembly in PHO5 gene expression

Kharerin, H., Bhat, P. J., Marko, J. F. & Padinhateeri, R., Feb 4 2016, In : Scientific reports. 6, 20319.

Research output: Contribution to journalArticle

1 Scopus citations

Selection on a Subunit of the NURF Chromatin Remodeler Modifies Life History Traits in a Domesticated Strain of Caenorhabditis elegans

Large, E. E., Xu, W., Zhao, Y., Brady, S. C., Long, L., Butcher, R. A., Andersen, E. C. & McGrath, P. T., Jul 2016, In : PLoS genetics. 12, 7, e1006219.

Research output: Contribution to journalArticle

14 Scopus citations

Self-propulsion and interactions of catalytic particles in a chemically active medium

Banigan, E. J. & Marko, J. F., Jan 25 2016, In : Physical Review E. 93, 1, 012611.

Research output: Contribution to journalArticle

14 Scopus citations

Set1/COMPASS and mediator are repurposed to promote epigenetic transcriptional memory

D’Urso, A., Takahashi, Y. H., Xiong, B., Marone, J., Coukos, R., Randise-Hinchliff, C., Wang, J. P., Shilatifard, A. & Brickner, J. H., Jun 23 2016, In : eLife. 5, JUN2016, e16691.

Research output: Contribution to journalArticle

45 Scopus citations

Sexually Antagonistic Male Signals Manipulate Germline and Soma of C. elegans Hermaphrodites

Aprison, E. Z. & Ruvinsky, I., Oct 24 2016, In : Current Biology. 26, 20, p. 2827-2833 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Skeletal light-scattering accelerates bleaching response in reef-building corals

Swain, T. D., DuBois, E., Gomes, A., Stoyneva, V. P., Radosevich, A. J., Henss, J., Wagner, M. E., Derbas, J., Grooms, H. W., Velazquez, E. M., Traub, J., Kennedy, B. J., Grigorescu, A. A., Westneat, M. W., Sanborn, K., Levine, S., Schick, M., Parsons, G., Biggs, B. C., Rogers, J. D. & 2 others, Backman, V. & Marcelino, L. A., Mar 21 2016, In : BMC Ecology. 16, 1, 10.

Research output: Contribution to journalArticle

13 Scopus citations

Spindle-E cycling between nuage and cytoplasm is controlled by Qin and PIWI proteins

Andress, A., Bei, Y., Fonslow, B. R., Giri, R., Wu, Y., Yates, J. R. & Carthew, R. W., Apr 1 2016, In : Journal of Cell Biology. 213, 2, p. 201-211 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Strategies to regulate transcription factor-mediated gene positioning and interchromosomal clustering at the nuclear periphery

Randise-Hinchliff, C., Coukos, R., Sood, V., Sumner, M. C., Zdraljevic, S., Sholl, L. M., Brickner, D. G., Ahmed, S., Watchmaker, L. & Brickner, J. H., Mar 16 2016, In : Journal of Cell Biology. 212, 6, p. 633-646 14 p.

Research output: Contribution to journalArticle

23 Scopus citations

Structural dynamics of potassium-channel gating revealed by single-molecule FRET

Wang, S., Vafabakhsh, R., Borschel, W. F., Ha, T. & Nichols, C. G., Jan 1 2016, In : Nature Structural and Molecular Biology. 23, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form

Wong, J. J. W., Paterson, R. G., Lamb, R. A. & Jardetzky, T. S., Jan 26 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 4, p. 1056-1061 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly

Louder, R. K., He, Y., López-Blanco, J. R., Fang, J., Chacón, P. & Nogales, E., Mar 31 2016, In : Nature. 531, 7596, p. 604-609 6 p.

Research output: Contribution to journalArticle

101 Scopus citations

Subnuclear positioning and interchromosomal clustering of the GAL1-10 locus are controlled by separable, interdependent mechanisms

Brickner, D. G., Sood, V., Tutucci, E., Coukos, R., Viets, K., Singer, R. H. & Brickner, J. H., Oct 1 2016, In : Molecular biology of the cell. 27, 19, p. 2980-2993 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Susan Lindquist 1949-2016

Morimoto, R. I., Dec 6 2016, In : Nature structural & molecular biology. 23, 12, p. 1072-1073 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry

Savaryn, J. P., Skinner, O. S., Fornelli, L., Fellers, R. T., Compton, P. D., Terhune, S. S., Abecassis, M. M. & Kelleher, N. L., Feb 16 2016, In : Journal of Proteomics. 134, p. 76-84 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Taxonomy of the order Mononegavirales: update 2016

Afonso, C. L., Amarasinghe, G. K., Bányai, K., Bào, Y., Basler, C. F., Bavari, S., Bejerman, N., Blasdell, K. R., Briand, F. X., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Chéng, J., Clawson, A. N., Collins, P. L., Dietzgen, R. G., Dolnik, O., Domier, L. L., Dürrwald, R. & 63 others, Dye, J. M., Easton, A. J., Ebihara, H., Farkas, S. L., Freitas-Astúa, J., Formenty, P., Fouchier, R. A. M., Fù, Y., Ghedin, E., Goodin, M. M., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kitajima, E. W., Kobinger, G. P., Kondo, H., Kurath, G., Lamb, R. A., Lenardon, S., Leroy, E. M., Li, C. X., Lin, X. D., Liú, L., Longdon, B., Marton, S., Maisner, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Randall, R. E., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Shi, M., Smither, S. J., Stenglein, M. D., Stone, D. M., Takada, A., Terregino, C., Tesh, R. B., Tian, J. H., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Verbeek, M., Volchkov, V. E., Wahl-Jensen, V., Walsh, J. A., Walker, P. J., Wang, D., Wang, L. F., Wetzel, T., Whitfield, A. E., Xiè, J., Yuen, K. Y., Zhang, Y. Z. & Kuhn, J. H., Aug 1 2016, In : Archives of Virology. 161, 8, p. 2351-2360 10 p.

Research output: Contribution to journalArticle

240 Scopus citations

The CopC Family: Structural and Bioinformatic Insights into a Diverse Group of Periplasmic Copper Binding Proteins

Lawton, T. J., Kenney, G. E., Hurley, J. D. & Rosenzweig, A. C., Apr 3 2016, In : Biochemistry. 55, 15, p. 2278-2290 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

The genetic basis of natural variation in Caenorhabditis elegans telomere length

Cook, D. E., Zdraljevic, S., Tanny, R. E., Seo, B., Riccardi, D. D., Noble, L. M., Rockman, M. V., Alkema, M. J., Braendle, C., Kammenga, J. E., Wang, J., Kruglyak, L., Félix, M. A., Lee, J. & Andersen, E. C., Sep 2016, In : Genetics. 204, 1, p. 371-383 13 p.

Research output: Contribution to journalArticle

36 Scopus citations

The NuRD complex component p66 suppresses photoreceptor neuron regeneration in planarians

Vásquez-Doorman, C. & Petersen, C. P., Jun 2016, In : Regeneration (Oxford, England). 3, 3, p. 168-78 11 p.

Research output: Contribution to journalArticle

The search engine for multi-proteoform complexes: An online tool for the identification and stoichiometry determination of protein complexes

Skinner, O. S., Schachner, L. F. & Kelleher, N. L., Jan 1 2016, In : Current Protocols in Bioinformatics. 2016, p. 13.30.1-13.30.11

Research output: Contribution to journalArticle

2 Scopus citations

The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection

Komuro, A., Homma, Y., Negoro, T., Barber, G. N. & Horvath, C. M., Nov 11 2016, In : Biochemical and Biophysical Research Communications. 480, 2, p. 187-193 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Unabridged analysis of human histone H3 by differential top-down mass spectrometry reveals hypermethylated proteoforms from MMSET/NSD2 overexpression

Zheng, Y., Fornelli, L., Compton, P. D., Sharma, S., Canterbury, J., Mullen, C., Zabrouskov, V., Fellers, R. T., Thomas, P. M., Licht, J. D., Senko, M. W. & Kelleher, N. L., Mar 2016, In : Molecular and Cellular Proteomics. 15, 3, p. 776-790 15 p.

Research output: Contribution to journalArticle

35 Scopus citations

Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration

Lander, R. & Petersen, C. P., Apr 13 2016, In : eLife. 5, April 2016, e12850.

Research output: Contribution to journalArticle

37 Scopus citations
2015
13 Scopus citations

Allosteric transcriptional regulation via changes in the overall topology of the core promoter

Philips, S. J., Canalizo-Hernandez, M., Yildirim, I., Schatz, G. C., Mondragón, A. & O'Halloran, T. V., Aug 21 2015, In : Science. 349, 6250, p. 877-881 5 p.

Research output: Contribution to journalArticle

58 Scopus citations

Analyzing internal fragmentation of electrosprayed ubiquitin ions during beam-type collisional dissociation

Durbin, K. R., Skinner, O. S., Fellers, R. T. & Kelleher, N. L., Feb 26 2015, In : Journal of the American Society for Mass Spectrometry. 26, 5, p. 782-787 6 p., 1078.

Research output: Contribution to journalArticle

17 Scopus citations

A new metal binding domain involved in cadmium, cobalt and zinc transport

Smith, A. T., Barupala, D., Stemmler, T. L. & Rosenzweig, A. C., Sep 20 2015, In : Nature Chemical Biology. 11, 9, p. 678-684 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63

Bao, X., Rubin, A. J., Qu, K., Zhang, J., Giresi, P. G., Chang, H. Y. & Khavari, P. A., Dec 18 2015, In : Genome Biology. 16, 1, 284.

Research output: Contribution to journalArticle

49 Scopus citations