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2014

Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant

Izumo, M., Pejchal, M., Schook, A. C., Lange, R. P., Walisser, J. A., Sato, T. R., Wang, X., Bradfield, C. A. & Takahashi, J. S., 2014, In : eLife. 3, e04617.

Research output: Contribution to journalArticle

72 Scopus citations

Diversity of the metal-transporting P1B-type ATPases

Smith, A. T., Smith, K. P. & Rosenzweig, A. C., Jan 1 2014, In : Journal of Biological Inorganic Chemistry. 19, 6, p. 947-960 14 p.

Research output: Contribution to journalArticle

47 Scopus citations

Dysregulation of the proteasome increases the toxicity of ALS-linked mutant SOD1

Kitamura, A., Inada, N., Kubota, H., Matsumoto, G., Kinjo, M., Morimoto, R. I. & Nagata, K., Mar 1 2014, In : Genes to Cells. 19, 3, p. 209-224 16 p.

Research output: Contribution to journalArticle

27 Scopus citations

Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus

Rey-Carrizo, M., Barniol-Xicota, M., Ma, C., Frigolé-Vivas, M., Torres, E., Naesens, L., Llabrés, S., Juárez-Jiménez, J., Luque, F. J., Degrado, W. F., Lamb, R. A., Pinto, L. H. & Vázquez, S., Jul 10 2014, In : Journal of Medicinal Chemistry. 57, 13, p. 5738-5747 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Effects of lipid environment on the conformational changes of an ABC importer

Rice, A. J., Alvarez, F. J. D., Davidson, A. L. & Pinkett, H. W., Jan 1 2014, In : Channels. 8, 4, p. 327-333 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effects of zinc on particulate methane monooxygenase activity and structure

Sirajuddin, S., Barupala, D., Helling, S., Marcus, K., Stemmler, T. L. & Rosenzweig, A. C., Aug 1 2014, In : Journal of Biological Chemistry. 289, 31, p. 21782-21794 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Enhanced light-harvesting capacity by micellar assembly of free accessory chromophores and LH1-like antennas

Harris, M. A., Sahin, T., Jiang, J., Vairaprakash, P., Parkes-Loach, P. S., Niedzwiedzki, D. M., Kirmaier, C., Loach, P. A., Bocian, D. F., Holten, D. & Lindsey, J. S., Jan 1 2014, In : Photochemistry and Photobiology. 90, 6, p. 1264-1276 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Flipping in the pore: Discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant s31n mutant of the influenza a virus m2 proton channel

Wu, Y., Canturk, B., Jo, H., Ma, C., Gianti, E., Klein, M. L., Pinto, L. H., Lamb, R. A., Fiorin, G., Wang, J. & Degrado, W. F., Dec 31 2014, In : Journal of the American Chemical Society. 136, 52, p. 17987-17995 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Fragmentation of integral membrane proteins in the gas phase

Skinner, O. S., Catherman, A. D., Early, B. P., Thomas, P. M., Compton, P. D. & Kelleher, N. L., May 6 2014, In : Analytical Chemistry. 86, 9, p. 4627-4634 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cells

Bose, S., Song, A. S., Jardetzky, T. S. & Lamb, R. A., Apr 2014, In : Journal of virology. 88, 8, p. 3925-3941 17 p.

Research output: Contribution to journalArticle

40 Scopus citations

Genome-wide analysis of regulation of gene expression and H3K9me2 distribution by JIL-1 kinase mediated histone H3S10 phosphorylation in Drosophila

Cai, W., Wang, C., Li, Y., Yao, C., Shen, L., Liu, S., Bao, X., Schnable, P. S., Girton, J., Johansen, J. & Johansen, K. M., May 2014, In : Nucleic acids research. 42, 9, p. 5456-5467 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

High-density nucleosome occupancy map of human chromosome 9p21-22 reveals chromatin organization of the type I interferon gene cluster

Freaney, J. E., Zhang, Q., Yigit, E., Kim, R., Widom, J., Wang, J. & Horvath, C. M., Sep 1 2014, In : Journal of Interferon and Cytokine Research. 34, 9, p. 676-685 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Histone H3S10 phosphorylation by the JIL-1 kinase in pericentric heterochromatin and on the fourth chromosome creates a composite H3S10phK9me2 epigenetic mark

Wang, C., Li, Y., Cai, W., Bao, X., Girton, J., Johansen, J. & Johansen, K. M., Jun 2014, In : Chromosoma. 123, 3, p. 273-280 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation

Popovic, R., Martinez-Garcia, E., Giannopoulou, E. G., Zhang, Q., Zhang, Q., Ezponda, T., Shah, M. Y., Zheng, Y., Will, C. M., Small, E. C., Hua, Y., Bulic, M., Jiang, Y., Carrara, M., Calogero, R. A., Kath, W. L., Kelleher, N. L., Wang, J. P., Elemento, O. & Licht, J. D., Sep 1 2014, In : PLoS genetics. 10, 9

Research output: Contribution to journalArticle

85 Scopus citations

Identification of the valence and coordination environment of the particulate methane monooxygenase copper centers by advanced EPR characterization

Culpepper, M. A., Cutsail, G. E., Gunderson, W. A., Hoffman, B. M. & Rosenzweig, A. C., Aug 20 2014, In : Journal of the American Chemical Society. 136, 33, p. 11767-11775 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Influenza A virus nucleoprotein selectively decreases neuraminidase gene-segment packaging while enhancing viral fitness and transmissibility

Brooke, C. B., Ince, W. L., Wei, J., Bennink, J. R., Yewdell, J. W. & Lamb, R. A., Nov 25 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 47, p. 16854-16859 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

In vitro evolution of high-titer, virus-like vesicles containing a single structural protein

Rose, N. F., Buonocore, L., Schell, J. B., Chattopadhyay, A., Bahl, K., Liu, X., Rose, J. K. & Lamb, R. A., Nov 25 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 47, p. 16866-16871 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Key interactions for clathrin coat stability

Böcking, T., Aguet, F., Rapoport, I., Banzhaf, M., Yu, A., Zeeh, J. C. & Kirchhausen, T., Jun 10 2014, In : Structure. 22, 6, p. 819-829 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Labeled EF-Tus for rapid kinetic studies of pretranslocation complex formation

Liu, W., Kavaliauskas, D., Schrader, J. M., Poruri, K., Birkedal, V., Goldman, E., Jakubowski, H., Mandecki, W., Uhlenbeck, O. C., Knudsen, C. R., Goldman, Y. E. & Cooperman, B. S., Oct 17 2014, In : ACS chemical biology. 9, 10, p. 2421-2431 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Male contraception: Past, present and future

Payne, C. & Goldberg, E., 2014, In : Current Molecular Pharmacology. 7, 2, p. 175-181 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Malfolded protein structure and proteostasis in lung diseases

Balch, W. E., Sznajder, J. I., Budinger, GR. S., Finley, D., Laposky, A. D., Cuervo, A. M., Benjamin, I. J., Barreiro, E., Morimoto, R. I., Postow, L., Weissman, A. M., Gail, D., Banks-Schlegel, S., Croxton, T. & Gan, W., Jan 1 2014, In : American journal of respiratory and critical care medicine. 189, 1, p. 96-103 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics

Chang, W. C., Guo, Y., Wang, C., Butch, S. E., Rosenzweig, A. C., Boal, A. K., Krebs, C. & Bollinger, J. M., Jan 1 2014, In : Science. 343, 6175, p. 1140-1144 5 p.

Research output: Contribution to journalArticle

63 Scopus citations

Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding

Roth, D. M., Hutt, D. M., Tong, J., Bouchecareilh, M., Wang, N., Seeley, T., Dekkers, J. F., Beekman, J. M., Garza, D., Drew, L., Masliah, E., Morimoto, R. I. & Balch, W. E., 2014, In : PLoS biology. 12, 11

Research output: Contribution to journalArticle

56 Scopus citations

Multiple-binding-site mechanism explains concentration-dependent unbinding rates of DNA-binding proteins

Sing, C. E., De La Cruz, M. O. & Marko, J. F., Apr 2014, In : Nucleic acids research. 42, 6, p. 3783-3791 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Non-canonical roles for Yorkie and Drosophila inhibitor of apoptosis 1 in epithelial tube size control

Robbins, R. M., Gbur, S. C. & Beitel, G. J., Jul 18 2014, In : PloS one. 9, 7, e101609.

Research output: Contribution to journalArticle

11 Scopus citations

Notch signaling regulates ovarian follicle formation and coordinates follicular growth

Vanorny, D. A., Prasasya, R. D., Chalpe, A. J., Kilen, S. M. & Mayo, K. E., 2014, In : Molecular Endocrinology. 28, 4, p. 499-511 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

Nucleosome positioning and kinetics near transcription-start-site barriers are controlled by interplay between active remodeling and DNA sequence

Parmar, J. J., Marko, J. F. & Padinhateeri, R., Jan 7 2014, In : Nucleic acids research. 42, 1, p. 128-136 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Optimizing capillary electrophoresis for top-down proteomics of 30-80 kDa proteins

Li, Y., Compton, P. D., Tran, J. C., Ntai, I. & Kelleher, N. L., Jan 1 2014, In : Proteomics. 14, 10, p. 1158-1164 7 p.

Research output: Contribution to journalArticle

56 Scopus citations
18 Scopus citations

Pervasive Divergence of Transcriptional Gene Regulation in Caenorhabditis Nematodes

Barrière, A. & Ruvinsky, I., Jun 2014, In : PLoS genetics. 10, 6, e1004435.

Research output: Contribution to journalArticle

12 Scopus citations

Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies

Welch, B. D., Paduch, M., Leser, G. P., Bergman, Z., Kors, C. A., Paterson, R. G., Jardetzky, T. S., Kossiakoff, A. A. & Lamb, R. A., 2014, In : Journal of virology. 88, 20, p. 11713-11725 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Probing the paramyxovirus fusion (F) protein-refolding event from pre- to postfusion by oxidative footprinting

Poor, T. A., Jones, L. M., Sood, A., Leser, G. P., Plasencia, M. D., Rempel, D. L., Jardetzky, T. S., Woods, R. J., Gross, M. L. & Lamb, R. A., Jun 24 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 25, p. E2596-E2605

Research output: Contribution to journalArticle

30 Scopus citations

Proteasome activation is a mechanism for pyrazolone small molecules displaying therapeutic potential in amyotrophic lateral sclerosis

Trippier, P. C., Zhao, K. T., Fox, S. G., Schiefer, I. T., Benmohamed, R., Moran, J., Kirsch, D. R., Morimoto, R. I. & Silverman, R. B., Sep 17 2014, In : ACS Chemical Neuroscience. 5, 9, p. 823-829 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition

Yu, A., Shibata, Y., Shah, B., Calamini, B., Lo, D. C. & Morimoto, R. I., Apr 15 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 15, p. E1481-E1490

Research output: Contribution to journalArticle

74 Scopus citations

Regiospecific formation of cobamide isomers is directed by CobT

Crofts, T. S., Hazra, A. B., Tran, J. LA., Sokolovskaya, O. M., Osadchiy, V., Ad, O., Pelton, J., Bauer, S. & Taga, M. E., Dec 16 2014, In : Biochemistry. 53, 49, p. 7805-7815 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

ROS1 signaling regulates epithelial differentiation in the epididymis

Jun, H. J., Roy, J., Smith, T. B., Wood, L. B., Lane, K., Woolfenden, S., Punko, D., Bronson, R. T., Haigis, K. M., Breton, S. & Charest, A., Sep 1 2014, In : Endocrinology. 155, 9, p. 3661-3673 13 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Setting appropriate boundaries: Fate, patterning and competence at the neural plate border

Groves, A. K. & LaBonne, C., May 1 2014, In : Developmental Biology. 389, 1, p. 2-12 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Single-molecule analysis uncovers the difference between the kinetics of DNA decatenation by bacterial topoisomerases i and III

Terekhova, K., Marko, J. F. & Mondragón, A., Oct 13 2014, In : Nucleic acids research. 42, 18, p. 11657-11667 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Single-molecule packaging initiation in real time by a viral DNA packaging machine from bacteriophage T4

Vafabakhsh, R., Kondabagil, K., Earnest, T., Lee, K. S., Zhang, Z., Dai, L., Dahmen, K. A., Rao, V. B. & Ha, T., Oct 21 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 42, p. 15096-15101 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Site-specific human histone H3 methylation stability: Fast K4me3 turnover

Zheng, Y., Tipton, J. D., Thomas, P. M., Kelleher, N. L. & Sweet, S. M. M., 2014, In : Proteomics. 14, 19, p. 2190-2199 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Small substrate transport and mechanism of a molybdate ATP binding cassette transporter in a lipid environment

Rice, A. J., Harrison, A., Alvarez, F. J. D., Davidson, A. L. & Pinkett, H. W., Jan 1 2014, In : Journal of Biological Chemistry. 289, 21, p. 15005-15013 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
20 Scopus citations

Stochastic ratchet mechanisms for replacement of proteins bound to DNA

Cocco, S., Marko, J. F. & Monasson, R., Jun 11 2014, In : Physical review letters. 112, 23, 238101.

Research output: Contribution to journalArticle

17 Scopus citations

Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways

Albright, J. C., Goering, A. W., Doroghazi, J. R., Metcalf, W. W. & Kelleher, N. L., Feb 1 2014, In : Journal of Industrial Microbiology and Biotechnology. 41, 2, p. 451-459 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Streptococcus sanguinis class Ib ribonucleotide reductase: High activity with both iron and manganese cofactors and structural insights

Makhlynets, O., Boal, A. K., Rhodes, D. L. V., Kitten, T., Rosenzweig, A. C. & Stubbe, J. A., Feb 28 2014, In : Journal of Biological Chemistry. 289, 9, p. 6259-6272 14 p.

Research output: Contribution to journalArticle

23 Scopus citations

Structural and Mechanistic Basis of Zinc Regulation Across the E. coli Zur Regulon

Gilston, B. A., Wang, S., Marcus, M. D., Canalizo-Hernández, M. A., Swindell, E. P., Xue, Y., Mondragón, A. & O'Halloran, T. V., 2014, In : PLoS biology. 12, 11

Research output: Contribution to journalArticle

51 Scopus citations

Structural conservation of the B subunit in the ammonia monooxygenase/particulate methane monooxygenase superfamily

Lawton, T. J., Ham, J., Sun, T. & Rosenzweig, A. C., Sep 2014, In : Proteins: Structure, Function and Bioinformatics. 82, 9, p. 2263-2267 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Structure, domain organization, and different conformational states of stem cell factor-induced intact KIT dimers

Opatowsky, Y., Lax, I., Tomé, F., Bleichert, F., Unger, V. M. & Schlessinger, J., Feb 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 5, p. 1772-1777 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Structure and protein-protein interactions of methanol dehydrogenase from Methylococcus capsulatus (Bath)

Culpepper, M. A. & Rosenzweig, A. C., Oct 7 2014, In : Biochemistry. 53, 39, p. 6211-6219 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

The C-Score: A bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomics

Leduc, R. D., Fellers, R. T., Early, B. P., Greer, J. B., Thomas, P. M. & Kelleher, N. L., Jul 3 2014, In : Journal of Proteome Research. 13, 7, p. 3231-3240 10 p.

Research output: Contribution to journalArticle

48 Scopus citations