Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Neurons Medicine & Life Sciences
Circadian Rhythm Medicine & Life Sciences
Circadian Clocks Medicine & Life Sciences
Light Medicine & Life Sciences
Brain Medicine & Life Sciences
Cricetinae Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Sleep Medicine & Life Sciences

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Research Output 1971 2017

A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers

Sebollela, A. , Cline, E. N. , Popova, I. , Luo, K. , Sun, X. , Ahn, J. , Barcelos, M. A. , Bezerra, V. N. , Lyra e Silva, N. M. , Patel, J. , Pinheiro, N. R. , Qin, L. A. , Kamel, J. M. , Weng, A. , Dinunno, N. , Bebenek, A. M. , Velasco, P. T. , Viola, K. L. , Lacor, P. N. , Ferreira, S. T. & 1 others Klein, W. L. 2017 (Accepted/In press) In : Journal of Neurochemistry.

Research output: Research - peer-reviewArticle

Single-Chain Antibodies
Amyloid
Alzheimer Disease
Molecular Weight
Oligomers

Alzheimer’s toxic amyloid beta oligomers: Unwelcome visitors to the Na/K ATPase alpha3 docking station

di Chiara, T., DiNunno, N., Clark, J., Bu, R. L., Cline, E. N., Rollins, M. G., Gong, Y., Brody, D. L., Sligar, S. G., Velasco, P. T., Viola, K. L. & Klein, W. L. Mar 1 2017 In : Yale Journal of Biology and Medicine. 90, 1, p. 45-61 17 p.

Research output: Research - peer-reviewArticle

Docks
Poisons
Oligomers
Amyloid
Neurons
1 Citations

Amyloid-β oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons

Seixas da Silva, G. S., Melo, H. M., Lourenco, M. V., Lyra e Silva, N. M., De Carvalho, M. B., Alves-Leon, S. V., De Souza, J. M., Klein, W. L., Da-Silva, W. S., Ferreira, S. T. & De Felice, F. G. May 5 2017 In : Journal of Biological Chemistry. 292, 18, p. 7395-7406 12 p.

Research output: Research - peer-reviewArticle

AMP-Activated Protein Kinases
Oligomers
Amyloid
Neurons
Defects