Pharmacology

Search results

• Strain-dependent effects on neurobehavioral and seizure phenotypes in Scn2a-K1422E mice

  Echevarria-Cooper, D. M. (Creator), Hawkins, N. A. (Creator) & Kearney, J. A. (Creator), Prism. Galter Health Sciences Library. Northwestern University, 2023

  DOI: 10.18131/wvn4p-y4z74, https://prism.northwestern.edu/doi/10.18131/wvn4p-y4z74

  Dataset

• Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30

  Haddad, J. F. (Contributor), Yang, Y. (Contributor), Takahashi, Y.-H. (Contributor), Joshi, M. (Contributor), Chaudhary, N. (Contributor), Woodfin, A. R. (Contributor), Benyoucef, A. (Contributor), Yeung, S. (Contributor), Brunzelle, J. S. (Contributor), Skiniotis, G. (Contributor), Brand, M. (Contributor), Shilatifard, A. (Contributor) & Couture, J.-F. (Contributor), Protein Data Bank (PDB), Aug 8 2018

  DOI: 10.2210/pdb6E2H/pdb, https://www.wwpdb.org/pdb?id=pdb_00006e2h

  Dataset

• 2.05 Angstrom Resolution Crystal Structure of Aminopeptidase B from Escherichia coli str. K-12 substr. MG1655.

  Lazar, J. T. (Contributor), Shuvalova, L. (Contributor), Rosas-Lemus, M. (Contributor), Kiryukhina, O. (Contributor), Satchell, K. J. F. (Contributor), Minasov, G. (Contributor), Lam, M. R. (Contributor), Sławek, J. (Contributor), Woinska, M. (Contributor), Shabalin, I. G. (Contributor), Palsson, B. Ø. (Contributor), Godzik, A. (Contributor), Minor, W. (Contributor), Gritsunov, A. (Contributor), Hou, J. (Contributor), Miks, C. D. (Contributor), Cooper, D. R. (Contributor) & Christendat, D. (Contributor), Protein Data Bank (PDB), Mar 27 2019

  DOI: 10.2210/pdb6OAD/pdb, https://www.wwpdb.org/pdb?id=pdb_00006oad

  Dataset

• 2.6 Angstrom Resolution Crystal Structure of Aminopeptidase B from Escherichia coli str. K-12 substr. MG1655

  Minasov, G. (Contributor), Lam, M. R. (Contributor), Rosas-Lemus, M. (Contributor), Sławek, J. (Contributor), Woinska, M. (Contributor), Shabalin, I. G. (Contributor), Shuvalova, L. (Contributor), Palsson, B. Ø. (Contributor), Godzik, A. (Contributor), Minor, W. (Contributor), Satchell, K. J. F. (Contributor), Gritsunov, A. (Contributor), Hou, J. (Contributor), Miks, C. D. (Contributor), Cooper, D. R. (Contributor), Christendat, D. (Contributor), Lazar, J. T. (Contributor) & Kiryukhina, O. (Contributor), Protein Data Bank (PDB), May 15 2019

  DOI: 10.2210/pdb6OV8/pdb, https://www.wwpdb.org/pdb?id=pdb_00006ov8

  Dataset

• 2.2 Angstrom Resolution Crystal Structure of P-Hydroxybenzoate Hydroxylase from Pseudomonas putida in Complex with FAD.

  Lazar, J. T. (Contributor), Shuvalova, L. (Contributor), Rosas-Lemus, M. (Contributor), Kiryukhina, O. (Contributor), Satchell, K. J. F. (Contributor) & Minasov, G. (Contributor), Protein Data Bank (PDB), Jun 13 2018

  DOI: 10.2210/pdb6DLL/pdb, https://www.wwpdb.org/pdb?id=pdb_00006dll

  Dataset

• Campylobacter jejuni ferric uptake regulator S1 metalated

  Sarvan, S. (Contributor), Charih, F. (Contributor), Askoura, M. (Contributor), Butcher, J. (Contributor), Brunzelle, J. S. (Contributor), Stintzi, A. (Contributor) & Couture, J.-F. (Contributor), Protein Data Bank (PDB), May 23 2018

  DOI: 10.2210/pdb6D57/pdb, https://www.wwpdb.org/pdb?id=pdb_00006d57

  Dataset

• SET7/9 in complex with TAF10 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), Protein Data Bank (PDB), Jul 28 2010

  DOI: 10.2210/pdb3M53/pdb, https://www.wwpdb.org/pdb?id=pdb_00003m53

  Dataset

• SET7/9 Y305F in complex with TAF10 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), Protein Data Bank (PDB), Jul 28 2010

  DOI: 10.2210/pdb3M54/pdb, https://www.wwpdb.org/pdb?id=pdb_00003m54

  Dataset

• Crystal structure of p38 alpha MAP kinase in complex with a novel isoform selective drug candidate

  Roy, S. M. (Contributor), Grum-Tokars, V. L. (Contributor), Schavocky, J. P. (Contributor), Saeed, F. (Contributor), Staniszewski, A. (Contributor), Teich, A. F. (Contributor), Arancio, O. (Contributor), Bachstetter, A. D. (Contributor), Webster, S. J. (Contributor), Van Eldik, L. J. (Contributor), Minasov, G. (Contributor), Anderson, W. F. (Contributor), Pelletier, J. C. (Contributor) & Watterson, D. M. (Contributor), Protein Data Bank (PDB), Feb 25 2015

  DOI: 10.2210/pdb4R3C/pdb, https://www.wwpdb.org/pdb?id=pdb_00004r3c

  Dataset

• SET7/9 Y305F in complex with TAF10-K189me1 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), Protein Data Bank (PDB), Jul 28 2010

  DOI: 10.2210/pdb3M55/pdb, https://www.wwpdb.org/pdb?id=pdb_00003m55

  Dataset

• Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y334F / H4-Lys20me1 / AdoHcy

  Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), Protein Data Bank (PDB), Nov 25 2008

  DOI: 10.2210/pdb3F9Y/pdb, https://www.wwpdb.org/pdb?id=pdb_00003f9y

  Dataset

• SET7/9 Y245A in complex with TAF10-K189me2 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), Protein Data Bank (PDB), Jul 28 2010

  DOI: 10.2210/pdb3M59/pdb, https://www.wwpdb.org/pdb?id=pdb_00003m59

  Dataset

• Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y334F / H4-Lys20 / AdoHcy

  Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), Protein Data Bank (PDB), Nov 25 2008

  DOI: 10.2210/pdb3F9W/pdb, https://www.wwpdb.org/pdb?id=pdb_00003f9w

  Dataset

• 3M59 : SET7/9 Y245A in complex with TAF10-K189me2 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), RCSB-PDB, 2010

  DOI: 10.2210/pdb3m59/pdb, https://www.rcsb.org/structure/3M59

  Dataset

• 3M5A : SET7/9 Y245A in complex with TAF10-K189me3 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), RCSB-PDB, 2010

  DOI: 10.2210/pdb3m5a/pdb, https://www.rcsb.org/structure/3M5A

  Dataset

• 3F9W : Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y334F / H4-Lys20 / AdoHcy

  Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), RCSB-PDB, 2008

  DOI: 10.2210/pdb3f9w/pdb, https://www.rcsb.org/structure/3F9W

  Dataset

• Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with Compound 5a bound to the Cryptic Pocket of nsp16

  Inniss, N. L. (Contributor), Kozic, J. (Contributor), Li, F. (Contributor), Rosas-Lemus, M. (Contributor), Minasov, G. (Contributor), Rybáček, J. (Contributor), Zhu, Y. (Contributor), Pohl, R. (Contributor), Shuvalova, L. (Contributor), Rulíšek, L. (Contributor), Brunzelle, J. S. (Contributor), Bednárová, L. (Contributor), Štefek, M. (Contributor), Kormaník, J. M. (Contributor), Andris, E. (Contributor), Šebestík, J. (Contributor), Li, A. S. M. (Contributor), Brown, P. J. (Contributor), Schmitz, U. (Contributor), Saikatendu, K. (Contributor), Chang, E. (Contributor), Nencka, R. (Contributor), Vedadi, M. (Contributor) & Satchell, K. J. F. (Contributor), Protein Data Bank (PDB), Oct 18 2023

  DOI: 10.2210/pdb8F4S/pdb, https://www.wwpdb.org/pdb?id=pdb_00008f4s

  Dataset

• Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based Aspartyl Protease Inhibitors

  Yedidi, R. S. (Contributor), Liu, Z. (Contributor), Wang, Y. (Contributor), Brunzelle, J. S. (Contributor), Kovari, I. A. (Contributor), Woster, P. M. (Contributor), Kovari, L. C. (Contributor) & Gupta, D. (Contributor), Protein Data Bank (PDB), Apr 4 2012

  DOI: 10.2210/pdb3R0Y/pdb, https://www.wwpdb.org/pdb?id=pdb_00003r0y

  Dataset

• 4F78 : Crystal Structure of Vancomycin Resistance D,D-dipeptidase VanXYg

  Meziane-Cherif, D. (Contributor), Stogios, P. J. (Contributor), Evdokimova, E. (Contributor), Savchenko, A. (Contributor), Courvalin, P. (Contributor), Minasov, G. (Contributor) & Anderson, W. F. (Contributor), RCSB-PDB, 2012

  DOI: 10.2210/pdb4f78/pdb, https://www.rcsb.org/structure/4F78

  Dataset

• 3M55 : SET7/9 Y305F in complex with TAF10-K189me1 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), RCSB-PDB, 2010

  DOI: 10.2210/pdb3m55/pdb, https://www.rcsb.org/structure/3M55

  Dataset

• 3M56 : SET7/9 Y305F in complex with TAF10-K189me2 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), RCSB-PDB, 2010

  DOI: 10.2210/pdb3m56/pdb, https://www.rcsb.org/structure/3M56

  Dataset

• 3M58 : SET7/9 Y245A in complex with TAF10-K189me1 peptide and AdoHcy

  Del Rizzo, P. A. (Contributor), Couture, J.-F. (Contributor), Dirk, L. M. A. (Contributor), Strunk, B. S. (Contributor), Roiko, M. S. (Contributor), Brunzelle, J. S. (Contributor), Houtz, R. L. (Contributor) & Trievel, R. C. (Contributor), RCSB-PDB, 2010

  DOI: 10.2210/pdb3m58/pdb, https://www.rcsb.org/structure/3M58

  Dataset

• 4MUQ : Crystal Structure of Vancomycin Resistance D,D-dipeptidase VanXYg in complex with D-Ala-D-Ala phosphinate analog

  Meziane-Cherif, D. (Contributor), Stogios, P. J. (Contributor), Evdokimova, E. (Contributor), Savchenko, A. (Contributor), Courvalin, P. (Contributor) & Anderson, W. F. (Contributor), RCSB-PDB, 2013

  DOI: 10.2210/pdb4muq/pdb, https://www.rcsb.org/structure/4MUQ

  Dataset

• Crystal structure of Ash2L N-terminal domain

  Sarvan, S. (Contributor), Avdic, V. (Contributor), Tremblay, V. (Contributor), Chaturvedi, C.-P. (Contributor), Zhang, P. (Contributor), Lanouette, S. (Contributor), Blais, A. (Contributor), Brunzelle, J. S. (Contributor), Brand, M. (Contributor) & Couture, J.-F. (Contributor), Protein Data Bank (PDB), Jun 8 2011

  DOI: 10.2210/pdb3S32/pdb, https://www.wwpdb.org/pdb?id=pdb_00003s32

  Dataset

• Spermidine N-acetyltransferase from Vibrio cholerae in complex with 2-[n-cyclohexylamino]ethane sulfonate.

  Filippova, E. V. (Contributor), Kuhn, M. L. (Contributor), Osipiuk, J. (Contributor), Kiryukhina, O. (Contributor), Joachimiak, A. (Contributor), Ballicora, M. A. (Contributor) & Anderson, W. F. (Contributor), Protein Data Bank (PDB), Nov 6 2013

  DOI: 10.2210/pdb4NCZ/pdb, https://www.wwpdb.org/pdb?id=pdb_00004ncz

  Dataset