Grants per year
- 100 - 125 out of 509 results
Search results
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Finished
Effects of XPC-5462, NBI921353, NBI921354, and NBI921355 on SCN2A (NaV1.2) gain-of-function (GOF) variants (hereinafter "Project")
George, A. L. (PD/PI) & Thompson, C. H. (Co-Investigator)
3/28/22 → 3/31/23
Project: Research project
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Compound Evaluation in Scn2aQ54 Mice
Kearney, J. A. (PD/PI)
3/28/22 → 5/27/24
Project: Research project
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Cell Penetration Profiling for Biotherapeutics
Rocklin, G. (PD/PI)
Tufts University, National Institute of General Medical Sciences
3/1/22 → 2/28/23
Project: Research project
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Low Cost, Chemically Defined, GM-Free Animal iPSC Generation, Culture, and Skeletal Muscle Differentiation
Burridge, P. (PD/PI)
2/11/22 → 2/11/24
Project: Research project
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Leveraging Systematic Chemical-Genetic Profiling as a Path to Expand Precision Medicine in Breast Cancer
Mendillo, M. L. (PD/PI), Mendillo, M. L. (PD/PI), Cristofanilli, M. (Co-Investigator), Cristofanilli, M. (Co-Investigator), Horiuchi, D. (Co-Investigator) & Horiuchi, D. (Co-Investigator)
U.S. Army Medical Research and Materiel Command
1/15/22 → 1/14/25
Project: Research project
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Exploring Novel Treatment Options for Patients with LMNA-Related Cardiomyopathy Using Patient-Specific hiPSCs
Burridge, P. (PD/PI) & Fonoudi, H. (Other)
1/1/22 → 12/31/23
Project: Research project
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Redefining PD pathophysiology mechanisms in the context of heterogeneous substantia nigra neuron subtypes
Awatramani, R. (PD/PI), Awatramani, R. (PD/PI), Bevan, M. D. (Co-Investigator), Bevan, M. D. (Co-Investigator), Dombeck, D. A. (Co-Investigator), Dombeck, D. A. (Co-Investigator), Parisiadou, L. (Co-Investigator), Parisiadou, L. (Co-Investigator), Surmeier Jr, D. J. (Co-Investigator) & Surmeier Jr, D. J. (Co-Investigator)
Michael J. Fox Foundation for Parkinson's Research
11/1/21 → 10/31/24
Project: Research project
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Effects of PRAX-562 on sodium current and excitability of neurons from a Scn2aQ54 gain-of-function mouse
George, A. L. (PD/PI), Kearney, J. A. (Co-Investigator) & Thompson, C. H. (Co-Investigator)
Praxis Precision Medicines, Inc.
10/13/21 → 9/30/22
Project: Research project
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Elucidating the phenome-wide impact of sex and gender on disease
Stranger, B. E. (PD/PI)
Vanderbilt University Medical Center, National Human Genome Research Institute
9/21/21 → 5/31/24
Project: Research project
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Rescue of Premature Truncation Mutation in SYNGAP1
George, A. L. (PD/PI)
9/1/21 → 6/30/23
Project: Research project
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Development of a novel anti-neuroinflammatory experimental therapeutic for epilepsy and Alzheimer's risk
Kearney, J. A. (PD/PI)
ImmunoChem Therapeutics, LLC, National Institute on Aging
9/1/21 → 8/31/23
Project: Research project
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Kinetic Imaging Plate Reader for Drug Discovery and Biology
George, A. L. (PD/PI), Arispe, L. (Other), Bass, J. (Other), Burridge, P. (Other), DeCaen, P. G. (Other), Gianneschi, N. (Other), Horvath, C. M. (Other), Kiskinis, E. (Other), Klein, W. L. (Other), Miller, R. J. (Other), Morimoto, R. I. (Other), Moskal, J. R. (Other), Penzes, P. (Other), Prakriya, M. (Other), Scheidt, K. A. (Other), Surmeier Jr, D. J. (Other) & Vafabakhsh, R. (Other)
Office of the Director, National Institutes of Health
9/1/21 → 8/31/23
Project: Research project
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Mechanisms of Translation Regulation by N4-acetylcytidine in Cancer Cells
Arango, D. (PD/PI) & Arango, D. (PD/PI)
9/1/21 → 8/31/24
Project: Research project
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Development of a novel anti-neuroinflammatory experimental therapeutic for epilepsy and Alzheimer's risk
Kearney, J. A. (PD/PI)
ImmunoChem Therapeutics, LLC, National Institute on Aging
9/1/21 → 11/30/23
Project: Research project
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Lead Identification of Novel Negative Allosteric Modulators of Cav1.3 L-Type Calcium Channels as a Disease Modifying Therapy for PD
Surmeier Jr, D. J. (PD/PI), Silverman, R. B. (Co-Investigator), Vanoye, C. G. (Co-Investigator) & Xie, Z. (Other)
Michael J. Fox Foundation for Parkinson's Research
8/1/21 → 7/31/23
Project: Research project
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Developing cell-penetrating miniproteins as a new class of therapeutics
Rocklin, G. (PD/PI)
National Institute of General Medical Sciences
8/1/21 → 7/31/23
Project: Research project
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Understanding and Improving Therapies for the Muscular Dystrophies
McNally, E. M. (PD/PI) & Demonbreun, A. R. (Co-Investigator)
University of Florida, National Institute of Arthritis and Musculoskeletal and Skin Diseases
8/1/21 → 7/31/22
Project: Research project
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Hyperthermia-induced seizure thresholds in Scn1a+/- mice
Kearney, J. A. (PD/PI)
7/6/21 → 7/5/22
Project: Research project
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The Cardiomyocyte Factory
Burridge, P. (PD/PI) & George, A. L. (Other)
7/1/21 → 6/30/23
Project: Research project
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Transcriptomal analysis of mouse and human dorsal root ganglia for the identification of novel targets for treating osteoarthritis pain
Miller, R. J. (PD/PI), Miller, R. J. (PD/PI), Belmadani, A. (Co-Investigator) & Belmadani, A. (Co-Investigator)
Rush University Medical Center, Rheumatology Research Foundation
7/1/21 → 6/30/23
Project: Research project
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Store-operated channels in the nervous system
Prakriya, M. (PD/PI), Apkarian, A. (Co-Investigator) & Yamashita, M. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
7/1/21 → 6/30/24
Project: Research project
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Unravelling the Role of Genome in Pediatric Long QT Syndrome variable expressivity
Mohamed, T. M. S. (PD/PI), Burridge, P. (Other), George, A. L. (Other), Roy-Puckelwartz, M. J. (Other), Stranger, B. E. (Other) & Webster, G. (Other)
7/1/21 → 7/31/22
Project: Research project
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Use of a Machine Learning Approach to Impute Gene Expression in African Americans
Perera, M. (PD/PI)
National Human Genome Research Institute
6/10/21 → 5/31/24
Project: Research project
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HiDef B8: Commercialization and scaled production of defined, robust, and cost-effective media for iPSCs
Burridge, P. (PD/PI)
Defined Biosciences, Inc., National Institute of General Medical Sciences
5/17/21 → 3/31/23
Project: Research project
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Targeting abnormal alveolar immune activation in COVID-19
Budinger, G. S. (PD/PI), Chandel, N. (Co-Investigator), Horvath, C. M. (Co-Investigator), Kelleher, N. L. (Co-Investigator), Misharin, A. (Co-Investigator), Prakriya, M. (Co-Investigator), Wunderink, R. G. (Co-Investigator) & Casalino Matsuda, M. S. (Other)
Northwestern Memorial Hospital
4/1/21 → 3/31/24
Project: Research project