Surgery, Cardiac Surgery Division

5/3/21 → 12/31/22

Project: Research project

Prot# ABT-CIP-10335: Implantation of the HeartMate 3 in Subjects with Heart Failure using Surgical Techniques Other Than Full Median Sternotomy (HM3 SWIFT)

St. Jude Medical Business Services, Inc.

3/3/21 → 3/2/22

Project: Research project

Prot#OCS-CAR-08242020: The Portable Organ Care System (OCS™) Heart For Resuscitation, Preservation and Assessment of Hearts from Donors after Circulatory Death Continued Access Protocol (OCS DCD Heart CAP)

Wearifi, Inc., National Institutes of Health

TransMedics, Inc.

2/17/21 → 2/17/24

Project: Research project

SBIR from Wearifi Inc

Xu, S. & Forbess, J. M.

9/8/20 → 8/31/22

Project: Research project

Prot#ONX1801.000-C: A Prospective, Randomized, Active (Warfarin) Controlled, Parallel-Arm Clinical Trial to Determine if Patients with an On-X Aortic Valve can be Maintained Safely and Effectively on the Factor Xa Inhibitor Apixaban (PROACT Xa)

La Jolla Pharmaceutical Company

CryoLife, Inc.

8/10/20 → 8/10/23

Project: Research project

Angiotensin II for Distributive Shock: Angiotensin as a first-line vasopressor for distributive shock for heart transplant and left ventricular assist device implantation recipients: A Pilot Study

Lewis, C. R. A. & Pham, D. T.

5/26/20 → 5/26/23

Project: Research project

Prot#OCS-CAR-03202019: Clinical Trial to Evaluate the Safety and Effectiveness of The Portable Organ Care System (OCS™) Heart For Resuscitation, Preservation and Assessment of Hearts from Donors after Circulatory Death (DCD Heart Trial)

Pham, D. T., Ghafourian, K. & Rich, J. D.

TransMedics, Inc.

3/19/20 → 3/19/23

Project: Research project

Prot# ABT-CIP-10304: REPAIR-MR: Percutaneous or Surgical Mitral Valve REpair in PAtients with PrImaRy MItral Regurgitation Whose Mitral Valve has been Determined to be Suitable for Correction by MV Repair Surgery

Davidson, C. J., Malaisrie, S. C., McCarthy, P. M. & Mutharasan, R. K.

Evalve, Inc.

3/12/20 → 3/11/24

Project: Research project

4D Virtual Catheter (vCath) Assessment of Hemodynamic Pathways in Aortopathy Pathogenesis

Markl, M., Bonow, R. O., Malaisrie, S. C., Ragin, A. & Elbaz, M.

National Heart, Lung, and Blood Institute

2/1/20 → 1/31/22

Project: Research project

A Randomized, Double-Blind, Placebo Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of QPI-1002 For the Prevention of Major Adverse Kidney Events(MAKE) in Subjects at High Risk for Acute Kidney Injury(AKI) Following Cardiac Surgery(Prot#QRK3

CTI Clinical Trial and Consulting Services, Quark Pharmaceuticals, Inc.

5/2/19 → 5/2/22

Project: Research project

Prot#CP2018-1: ICE AFIB IDE Study: AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment during Concomitant On-Pump Endo

AtriCure, Inc.

4/17/19 → 4/17/22

Project: Research project

Product Surveillance Registry (PSR)

Medtronic, Inc.

1/24/19 → 1/24/22

Project: Research project

ExCEED - A Prospective, Single-arm, Controlled, Multicenter Study to Establish the Safety and Effectiveness of the CENTERA THV System in Intermediate Risk Patients who have Symptomatic, Severe, Calcific, Aortic Stenosis Requiring Aortic Valve Replacement

11/28/18 → 11/28/21

Project: Research project

SHAPE: Seeing the Heart with AI Powered Echo

Bay Labs, Inc.

10/2/18 → 10/2/21

Project: Research project

Prot#2015-08 MVIV: PARTNER 3 Mitral Valve-in-Valve - A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients with a Failing Mitral Bioprosthetic Valve

National Heart, Lung, and Blood Institute

5/10/18 → 5/10/24

Project: Research project

Functional Cardiovascular 4D MRI in Congenital Heart Disease

Markl, M., Barker, A. J., Bonow, R. O., Carr, J., Kim, D., Malaisrie, S. C., McCarthy, P. M., Ragin, A. & Wang, L.

4/1/18 → 3/31/22

Project: Research project

APOLLO Trial Clinical Investigation Plan - Transcatheter Mitral Valve Replacement with the Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation

Malaisrie, S. C. & McCarthy, P. M.

Medtronic, Inc.

1/25/18 → 1/25/23

Project: Research project

Prot# IP-0017-16: A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro Thoracic Stent-Graft in Subjects with an Acute, Complicated Type B Aortic Dissection

Bolton Medical, Inc.

6/16/17 → 6/16/23

Project: Research project

P3 AVIV Registry - A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Aortic Bioprosthetic Valve

Edwards Lifesciences Corporation

5/16/17 → 5/16/23

Project: Research project

Prot# CIP-1403: INTREPID - Evaluation of the Safety and Performance of the Twelve Transcatheter Mitral Valve Replacement System in High Risk Patients with Severe Symptomatic Mitral Regurgitation

Medtronic, Inc.

5/10/17 → 5/10/23

Project: Research project

Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients with AsYmptomatic Severe Aortic Stenosis: EARLY-TAVR trial

4/4/17 → 4/4/23

Project: Research project

Prot#2015-08:PARTNER 3 Trial: A Prospective, Randomized, Controlled, Multi-Center Study to Establish the Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients Requiring Aortic Valve Replacement who have Severe, Calcific,

5/17/16 → 5/17/22

Project: Research project

Prot #HYBRID-002: Evaluation of the Thoraflex™ Hybrid Device for Use in the Repair or Replacement of the Ascending Aorta, Aortic Arch and Descending Aorta in an Open Surgical Procedure.