Surgery, Surgical Oncology Division

Research Output 1975 2020

1996
12 Citations (Scopus)

Lack of association between tumor necrosis and hsp-27 expression in primary breast cancer

Storm, F. K., Mahvi, D. M. & Gilchrist, K. W., Jan 1 1996, In : Journal of Surgical Oncology. 61, 1, p. 14-16 3 p.

Research output: Contribution to journalArticle

HSP27 Heat-Shock Proteins
Necrosis
Ductal Carcinoma
Breast Neoplasms
Neoplasms
5 Citations (Scopus)

Modification of the radiation response by the administration of exogenous genes

Hanna, N. N., Hallahan, D. E., Wayne, J. D. & Weichselbaum, R. R., Jan 1 1996, In : Seminars in Radiation Oncology. 6, 4, p. 321-328 8 p.

Research output: Contribution to journalArticle

Genetic Therapy
Prodrugs
Radiation
Genes
Enzymes
6 Citations (Scopus)

Mucinous ductal ectasia in an octogenarian: Successful treatment with the Whipple procedure

Block, K. P., Mahvi, D., Voytovich, M., Watkins, J. L., Mosley, R. & Reichelderfer, M., Feb 1 1996, In : American Journal of Gastroenterology. 91, 2, p. 388-390 3 p.

Research output: Contribution to journalArticle

Pathologic Dilatations
Mucins
Natural History
Pancreatic Neoplasms
Therapeutics

Nevirapine: a review of its development, pharmacological profile and potential for clinical use

Murphy, RL. & Montaner, J., 1996, In : Exp Opin Invest Drugs. 5, 9, p. 1079-1099 21 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Particle-mediated gene transfer of granulocyte-macrophage colony-stimulating factor cDNA to tumor cells: Implications for a clinically relevant tumor vaccine

Mahvi, D. M., Burkholder, J. K., Turner, J., Culp, J., Malter, J. S., Sondel, P. M. & Yang, N. S., Aug 20 1996, In : Human Gene Therapy. 7, 13, p. 1535-1543 9 p.

Research output: Contribution to journalArticle

Cancer Vaccines
Granulocyte-Macrophage Colony-Stimulating Factor
Complementary DNA
Genes
Neoplasms
6 Citations (Scopus)

Toremifene, a novel antiestrogen, can overcome hsp27-induced drug resistance in human breast cancer cells

Mahvi, D. M., Carper, S. W., Yu, C. O., McCausland, T. A. & Kristian Storm, F., Jun 1 1996, In : Endocrine. 4, 3, p. 269-275 7 p.

Research output: Contribution to journalArticle

Toremifene
Estrogen Receptor Modulators
Drug Resistance
Doxorubicin
Breast Neoplasms
104 Citations (Scopus)

Tumor necrosis factor α (TNF-α) gene therapy targeted by ionizing radiation selectively damages tumor vasculature

Mauceri, H. J., Hanna, N. N., Wayne, J. D., Hallahan, D. E., Hellman, S. & Weichselbaum, R. R., Oct 1 1996, In : Cancer Research. 56, 19, p. 4311-4314 4 p.

Research output: Contribution to journalArticle

Ionizing Radiation
Genetic Therapy
Tumor Necrosis Factor-alpha
Neoplasms
Radiation
1997

Diagnosis and management of infection in the immunocompromised host

Noskin, GA., Phair, JP. & Murphy, RL., 1997, 5th Edition of Biologic and Clinical Basis of Infectious Diseases. Shulman, ST., Phair, JP., Peterson, LR. & Warren, JR. (eds.). Pennsylvania: Saunders, p. 361-381

Research output: Chapter in Book/Report/Conference proceedingChapter

31 Citations (Scopus)

DNA cancer vaccines: A gene gun approach

Mahvi, D. M., Sheehy, M. J. & Yang, N. S., Jan 1 1997, In : Immunology and Cell Biology. 75, 5, p. 456-460 5 p.

Research output: Contribution to journalReview article

Cancer Vaccines
DNA Vaccines
Firearms
Genes
Cytokines
86 Citations (Scopus)

Hepatic cryosurgery with intraoperative US guidance

Lee, F. T., Mahvi, D. M., Chosy, S. G., Onik, G. M., Wong, W. S., Littrup, P. J. & Scanlan, K. A., Jan 1 1997, In : Radiology. 202, 3, p. 624-632 9 p.

Research output: Contribution to journalReview article

Interventional Ultrasonography
Intraoperative Period
Cryosurgery
Cryotherapy
Liver Neoplasms

HIV AIDS Infections. Handbooks in Healthcare.

Phair, JP. & Murphy, RL., 1997, Newtown, PA.

Research output: Book/ReportBook

53 Citations (Scopus)

Perivascular and intralesional tissue necrosis after hepatic cryoablation: Results in a porcine model

Weber, S. M., Lee, F. T., Chinn, D. O., Warner, T., Chosy, S. G. & Mahvi, D. M., Oct 1997, In : Surgery. 122, 4, p. 742-747 6 p.

Research output: Contribution to journalArticle

Cryosurgery
Necrosis
Swine
Liver
Freezing
46 Citations (Scopus)

Phase I/IB study of immunization with autologous tumor cells transfected with the GM-CSF gene by particle-mediated transfer in patients with melanoma or sarcoma

Mahvi, D. M., Sondel, P. M., Yang, N. S., Albertini, M. R., Hank, J., Heiner, J., Gan, J., Swain, W. & Logrono, R., May 1 1997, In : Human Gene Therapy. 8, 7, p. 875-891 17 p.

Research output: Contribution to journalReview article

Patient Transfer
Granulocyte-Macrophage Colony-Stimulating Factor
Sarcoma
Melanoma
Immunization
120 Citations (Scopus)

Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan

Bailey, H. H., Ripple, G., Tutsch, K. D., Arzoomanian, R. Z., Alberti, D., Feierabend, C., Mahvi, D., Schink, J., Pomplun, M., Mulcahy, R. T. & Wilding, G., Dec 3 1997, In : Journal of the National Cancer Institute. 89, 23, p. 1789-1796 8 p.

Research output: Contribution to journalArticle

Buthionine Sulfoximine
Melphalan
Glutathione
Neoplasms
Appointments and Schedules
11 Citations (Scopus)

Potential use of image analysis for the evaluation of cellular predicting factors for therapeutic response in breast cancers

Bacus, S., Chin, D., Stewart, J., Zelnick, C., Mahvi, D. & Gilchrist, K., Aug 1 1997, In : Analytical and Quantitative Cytology and Histology. 19, 4, p. 316-328 13 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Biological Factors
Therapeutics
P-Glycoprotein
Progesterone Receptors

Sexually Transmitted Diseases

Palella, F. & Murphy, R., 1997, 5th Edition of Biologic and Clinical Basis of Infectious Diseases. Shulman, ST. & Phair, JP. (eds.). Pennsylvania: Saunders, p. 208-234

Research output: Chapter in Book/Report/Conference proceedingChapter

59 Citations (Scopus)

The presence of K-12 ras mutations in duodenal adenocarcinomas and the absence of ras mutations in other small bowel adenocarcinomas and carcinoid tumors

Younes, N., Fulton, N., Tanaka, R., Wayne, J., Straus, F. H. & Kaplan, E. L., May 1 1997, In : Cancer. 79, 9, p. 1804-1808 5 p.

Research output: Contribution to journalArticle

Carcinoid Tumor
Adenocarcinoma
Mutation
Small Intestine
Codon
57 Citations (Scopus)

The role of frozen section analysis of margins during breast conservation surgery

Weber, S., Storm, F. K., Stitt, J. & Mahvi, D. M., Oct 9 1997, In : Cancer Journal from Scientific American. 3, 5, p. 273-277 5 p.

Research output: Contribution to journalArticle

Frozen Sections
Breast
Segmental Mastectomy
Recurrence
Biopsy
8 Citations (Scopus)

Use of In-111 pentetreotide scintigraphy in the diagnosis of a midgut carcinoid causing Cushing's syndrome

Segu, V. B., Mahvi, D. M., Wilson, M. A., Hale, S. J., Warner, T. F., Meredith, M. & Shenker, Y., Jul 1 1997, In : European Journal of Endocrinology. 137, 1, p. 79-83 5 p.

Research output: Contribution to journalArticle

Cushing Syndrome
Carcinoid Tumor
Radionuclide Imaging
Adrenocorticotropic Hormone
Ileum
124 Citations (Scopus)

Use of the pneumo sleeve as an adjunct in laparoscopic nephrectomy

Nakada, S. Y., Moon, T. D., Gist, M. & Mahvi, D., Apr 1997, In : Urology. 49, 4, p. 612-613 2 p.

Research output: Contribution to journalArticle

Touch
Hemostasis
Nephrectomy
Abdomen
Laparoscopy
82 Citations (Scopus)

Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts

Hanna, N. N., Mauceri, H. J., Wayne, J. D., Hallahan, D. E., Kufe, D. W. & Weichselbaum, R. R., Oct 1 1997, In : Cancer Research. 57, 19, p. 4205-4209 5 p.

Research output: Contribution to journalArticle

Cytosine Deaminase
Flucytosine
Heterografts
Genetic Therapy
Radiation
1998
6 Citations (Scopus)

A new look at an old option in the treatment of early-stage prostate cancer: Hormone therapy as an alternative to watchful waiting

Yang, F. E., Song, P. Y., Wayne, J., Vaida, F. & Vijayakumar, S., Sep 1998, In : Medical Hypotheses. 51, 3, p. 243-251 9 p.

Research output: Contribution to journalArticle

Watchful Waiting
Complementary Therapies
Prostatic Neoplasms
Hormones
Survival

Helminthic Infections in Pregnancy

Murphy, RL., 1998, Principles of Medical Therapy in Pregnancy. Gleicher, NB. (ed.). Connecticut: Appleton & Lange, p. 706-710

Research output: Chapter in Book/Report/Conference proceedingChapter

32 Citations (Scopus)

Hepatic cryoablation: US monitoring of extent of necrosis in normal pig liver

Weber, S. M., Lee, F. T., Warner, T. F., Chosy, S. G. & Mahvi, D. M., Apr 1 1998, In : Radiology. 207, 1, p. 73-78 6 p.

Research output: Contribution to journalArticle

Cryosurgery
Ultrasonography
Necrosis
Swine
Liver
1999
81 Citations (Scopus)

CT-monitored percutaneous cryoablation in a pig liver model: Pilot study

Lee, F. T., Chosy, S. G., Littrup, P. J., Warner, T. F., Kuhlman, J. E. & Mahvi, D. M., Jan 1 1999, In : Radiology. 211, 3, p. 687-692 6 p.

Research output: Contribution to journalArticle

Cryosurgery
Swine
Liver
Ice
oxidized cellulose
37 Citations (Scopus)

Granulocyte-macrophage colony-stimulating factor (GM-CSF) secreted by cDNA-transfected tumor cells induces a more potent antitumor response than exogenous GM-CSF

Shi, F. S., Weber, S., Gan, J., Rakhmilevich, A. L. & Mahvi, D. M., Jan 1 1999, In : Cancer Gene Therapy. 6, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

Granulocyte-Macrophage Colony-Stimulating Factor
Complementary DNA
Neoplasms
Mastocytoma
Cytokines
7 Citations (Scopus)

Hepatic cryosurgery via minilaparotomy in a porcine model. An alternative to open cryosurgery

Lee, F. T., Chosy, S. G., Weber, S. M., Littrup, P. J., Warner, T. F. & Mahvi, D. M., Mar 1 1999, In : Surgical endoscopy. 13, 3, p. 253-259 7 p.

Research output: Contribution to journalArticle

Cryosurgery
Laparotomy
Swine
Liver
Agar
22 Citations (Scopus)

Interleukin-12 gene transfer results in CD8-dependent regression of murine CT26 liver tumors

Weber, S. M., Shi, F., Heise, C., Warner, T. & Mahvi, D. M., Jan 1 1999, In : Annals of Surgical Oncology. 6, 2, p. 186-194 9 p.

Research output: Contribution to journalArticle

Interleukin-12
Liver
Genes
Neoplasms
Transfection
32 Citations (Scopus)

Radiofrequency ablation of hepatic malignancies: Is heat better than cold? Editorial

Mahvi, D. M. & Lee F.T., J., Dec 1 1999, In : Annals of surgery. 230, 1, p. 9-11 3 p.

Research output: Contribution to journalEditorial

Diathermy
Cryosurgery
Liver Neoplasms
Hot Temperature
Liver
73 Citations (Scopus)

Synergistic inhibition of tumor growth in a murine mammary adenocarcinoma model by combinational gene therapy using IL-12, pro-IL-18, and IL-1β converting enzyme cDNA

Oshikawa, K., Shi, F., Rakhmilevich, A. L., Sondel, P. M., Mahvi, D. M. & Yang, N. S., Nov 9 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 23, p. 13351-13356 6 p.

Research output: Contribution to journalArticle

Interleukin-18
Interleukin-12
Interleukin-1
Genetic Therapy
Adenocarcinoma
5 Citations (Scopus)

Targeted antiestrogens for the prevention of breast cancer

Bentrem, D. J. & Craig Jordan, V., Dec 1 1999, In : Oncology Research. 11, 9, p. 401-407 7 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Tamoxifen
Breast Neoplasms
Selective Estrogen Receptor Modulators
Osteoporosis
2000
95 Citations (Scopus)

Allosteric silencing of activating function 1 in the 4-hydroxytamoxifen estrogen receptor complex is induced by substituting glycine for aspartate at amino acid 351

MacGregor Schafer, J., Liu, H., Bentrem, D. J., Zapf, J. W. & Jordan, V. C., Sep 15 2000, In : Cancer Research. 60, 18, p. 5097-5105 9 p.

Research output: Contribution to journalArticle

Aspartic Acid
Estrogen Receptors
Glycine
Amino Acids
Estrogens
171 Citations (Scopus)

Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice

Yao, K., Lee, E. S., Bentrem, D. J., England, G., Schafer, J. I. M. G., O'Regan, R. M. & Jordan, V. C., May 1 2000, In : Clinical Cancer Research. 6, 5, p. 2028-2036 9 p.

Research output: Contribution to journalArticle

Tamoxifen
Nude Mice
Estradiol
Breast Neoplasms
Neoplasms
128 Citations (Scopus)

CT versus sonography for monitoring radiofrequency ablation in a porcine liver

Cha, C. H., Lee F.T., J., Gurney, J. M., Markhardt, B. K., Warner, T. F., Kelcz, F. & Mahvi, D. M., Jan 1 2000, In : American Journal of Roentgenology. 175, 3, p. 705-711 7 p.

Research output: Contribution to journalArticle

Ultrasonography
Swine
Liver
Artifacts
Spiral Computed Tomography
3 Citations (Scopus)

Laparoscopic lumbar spinal fusion: The role of the general surgeon

Staelin, S. T., Zdeblick, T. A. & Mahvi, D. M., Jan 1 2000, In : Journal of Laparoendoscopic and Advanced Surgical Techniques - Part A. 10, 6, p. 297-304 8 p.

Research output: Contribution to journalReview article

Spinal Fusion
Postoperative Pain
Patient Selection
Length of Stay
Spine

Lopinavir, a viewpoint

Murphy, RL., 2000, In : Drugs. 60, p. 1380-1381 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Minilaparotomy vs the percutaneous approach for minimally invasive hepatic cryosurgery

Pistorius, G., Menger, M. D., Feifel, G., Lee F.T., J. & Mahvi, D. M., Jan 1 2000, In : Surgical Endoscopy. 14, 2, p. 207-209 3 p.

Research output: Contribution to journalArticle

Cryosurgery
Laparotomy
Liver
Neoplasms
11 Citations (Scopus)

Screening for occult nodal metastasis in squamous cell carcinoma of the vulva

Leys, C. M., Hartenbach, E. M., Hafez, G. R. & Mahvi, D. M., Jan 1 2000, In : International Journal of Gynecological Pathology. 19, 3, p. 243-247 5 p.

Research output: Contribution to journalArticle

Vulva
Squamous Cell Carcinoma
Lymph Nodes
Neoplasm Metastasis
Hematoxylin
2001
45 Citations (Scopus)

Analysis of cross-resistance of the selective estrogen receptor modulators arzoxifene (LY353381) and LY117018 in tamoxifen-stimulated breast cancer xenografts

MacGregor Schafer, J., Lee, E. S., Dardes, R. C., Bentrem, D., O’Regan, R. M., de Los Reyes, A. & Jordan, V. C., Jan 1 2001, In : Clinical Cancer Research. 7, 8, p. 2505-2512 8 p.

Research output: Contribution to journalArticle

LY 353381
LY 117018
Selective Estrogen Receptor Modulators
Tamoxifen
Heterografts
145 Citations (Scopus)

Anaphylactic reactions to isosulfan blue dye during sentinel lymph node biopsy for breast cancer

Albo, D., Wayne, J. D., Hunt, K. K., Rahlfs, T. F., Singletary, S. E., Ames, F. C., Feig, B. W., Ross, M. I. & Kuerer, H. M., Dec 3 2001, In : American journal of surgery. 182, 4, p. 393-398 6 p.

Research output: Contribution to journalArticle

Sentinel Lymph Node Biopsy
Anaphylaxis
Coloring Agents
Breast Neoplasms
Technetium Tc 99m Sulfur Colloid
46 Citations (Scopus)

Anaphylaxis during breast cancer lymphatic mapping [2]

Kuerer, H. M., Wayne, J. D. & Ross, M. I., Jan 1 2001, In : Surgery. 129, 1, p. 119-120 2 p.

Research output: Contribution to journalLetter

Anaphylaxis
Breast Neoplasms
7 Citations (Scopus)

B7.1 expression eliminates tumor resistance to IL-12 gene therapy

Heise, C. P., Shi, F., Albertini, M. R. & Mahvi, D. M., Jan 1 2001, In : Cancer Gene Therapy. 8, 2, p. 118-127 10 p.

Research output: Contribution to journalArticle

Interleukin-12
Genetic Therapy
Neoplasms
Experimental Melanomas
Complementary DNA
39 Citations (Scopus)

Control of the estrogen-like actions of the tamoxifen-estrogen receptor complex by the surface amino acid at position 351

Levenson, A. S., Macgregor Schafer, J. I., Bentrem, D. J., Pease, K. M. & Jordan, V. C., Jan 1 2001, In : Journal of Steroid Biochemistry and Molecular Biology. 76, 1-5, p. 61-70 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Estrogen Receptor Modulators
Estrogen Receptors
Estrogens
Amino Acids
184 Citations (Scopus)

Effect of vascular occlusion on radiofrequency ablation of the liver: Results in a porcine model

Chinn, S. B., Lee, J., Kennedy, G. D., Chinn, C., Johnson, C. D., Winter, T. C., Warner, T. F. & Mahvi, D. M., Jan 1 2001, In : American Journal of Roentgenology. 176, 3, p. 789-795 7 p.

Research output: Contribution to journalArticle

Blood Vessels
Swine
Hepatic Artery
Temperature
Liver
24 Citations (Scopus)

Effects of the new selective estrogen receptor modulator LY353381.HCl (Arzoxifene) on human endometrial cancer growth in athymic mice

Dardes, R. C., MacGregor Schafer, J., Jordan, V. C., O’Regan, R. M. & Bentrem, D., Jan 1 2001, In : Clinical Cancer Research. 7, 12, p. 4149-4155 7 p.

Research output: Contribution to journalArticle

LY 353381
Selective Estrogen Receptor Modulators
Tamoxifen
Endometrial Neoplasms
Nude Mice
82 Citations (Scopus)
Hypoparathyroidism
Parathyroidectomy
Thyroidectomy
Calcium
Serum
104 Citations (Scopus)

Hepatic bipolar radio-frequency ablation between separated multiprong electrodes

Haemmerich, D., Staelin, S. T., Tungjitkusolmun, S., Lee, F. T., Mahvi, D. M. & Webster, J. G., Oct 1 2001, In : IEEE Transactions on Biomedical Engineering. 48, 10, p. 1145-1152 8 p.

Research output: Contribution to journalArticle

Ablation
Electrodes
Liver
Tumors
Energy dissipation
28 Citations (Scopus)

Interleukin 12 gene transfer into skin distant from the tumor site elicits antimetastatic effects equivalent to local gene transfer

Oshikawa, K., Rakhmilevich, A. L., Shi, F., Sondel, P. M., Yang, N. S. & Mahvi, D. M., Jan 20 2001, In : Human Gene Therapy. 12, 2, p. 149-160 12 p.

Research output: Contribution to journalArticle

Interleukin-12
Skin
Genes
Neoplasms
Neoplasm Metastasis
68 Citations (Scopus)

Molecular mechanism of action at estrogen receptor α of a new clinically relevant antiestrogen (GW7604) related to tamoxifen

Bentrem, D. J., Dardes, R. C., Liu, H., Macgregor-Schafer, J., Zapf, J. W. & Jordan, V. C., Jan 1 2001, In : Endocrinology. 142, 2, p. 838-846 9 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Tamoxifen
Estrogen Receptors
Transforming Growth Factors
Estrogens
12 Citations (Scopus)

Multimodality management of localized pancreatic cancer.

Wayne, J. D., Wolff, R. A., Pisters, P. W. & Evans, D. B., Jan 1 2001, In : Cancer journal (Sudbury, Mass.). 7 Suppl 1, p. S35-46

Research output: Contribution to journalReview article

Pancreatic Neoplasms
Pancreaticoduodenectomy
Pancreas
Adenocarcinoma
Therapeutics