Aaron Hamvas

  • 5169 Citations
1990 …2020

Research output per year

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Personal profile

Research Interests

Dr. Hamvas has a longstanding interest in genetic contributions to lung diseases that affect newborns, children and adults, he has combined his clinical interests in the care of newborn respiratory diseases with an integrated investigative program to understand the modifiable factors that influence outcomes of newborns.

Mutations in pulmonary surfactant associated genes result in newborn respiratory distress but can also contribute to idiopathic pulmonary fibrosis in adults. We use exome sequencing to identify genes and gene pathways that might inform variability in penetrance of these mutations and also provide further insights into the development of chronic lung disease (bronchopulmonary dysplasia) in premature newborns. We are also part of an NIH-funded clinical observational study that combines analysis of continuous physiologic data streams, echocardiographic measures, and measures of autonomic nervous system function to identify physiologic perturbations that have an impact on cardiac, respiratory, and neurologic outcomes of premature babies.

Diffuse lung diseases in newborns and children

Certifications and Licenses

Neonatal-Perinatal Medicine

Training Experience

1984Residency, Saint Louis Children's Hospital
1990Fellowship, Saint Louis Children's Hospital

Education/Academic qualification

MD, Washington University St. Louis

… → 1981

Research interests

  • Developmental Biology
  • Genomics
  • Neonatology
  • Prenatal Environment and Developmental Outcomes
  • Respiratory Diseases

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Research Output

Skin-interfaced biosensors for advanced wireless physiological monitoring in neonatal and pediatric intensive-care units

Chung, H. U., Rwei, A. Y., Hourlier-Fargette, A., Xu, S., Lee, K. H., Dunne, E. C., Xie, Z., Liu, C., Carlini, A., Kim, D. H., Ryu, D., Kulikova, E., Cao, J., Odland, I. C., Fields, K. B., Hopkins, B., Banks, A., Ogle, C., Grande, D., Park, J. B. & 42 others, Kim, J., Irie, M., Jang, H., Lee, J. H., Park, Y., Kim, J., Jo, H. H., Hahm, H., Avila, R., Xu, Y., Namkoong, M., Kwak, J. W., Suen, E., Paulus, M. A., Kim, R. J., Parsons, B. V., Human, K. A., Kim, S. S., Patel, M., Reuther, W., Kim, H. S., Lee, S. H., Leedle, J. D., Yun, Y., Rigali, S., Son, T., Jung, I., Arafa, H., Soundararajan, V. R., Ollech, A., Shukla, A., Bradley, A., Schau, M., Rand, C. M., Marsillio, L. E., Harris, Z. L., Huang, Y., Hamvas, A., Paller, A. S., Weese-Mayer, D. E., Lee, J. Y. & Rogers, J. A., Mar 1 2020, In : Nature Medicine. 26, 3, p. 418-429 12 p.

Research output: Contribution to journalArticle

  • 4 Scopus citations

    Urine gastrin-releasing peptide in the first week correlates with bronchopulmonary dysplasia and post-prematurity respiratory disease

    Voynow, J. A., Fisher, K., Sunday, M. E., Cotten, C. M., Hamvas, A., Hendricks-Muñoz, K. D., Poindexter, B. B., Pryhuber, G. S., Ren, C. L., Ryan, R. M., Sharp, J. K., Young, S. P., Zhang, H., Greenberg, R. G., Herring, A. H. & Davis, S. D., Apr 1 2020, In : Pediatric Pulmonology. 55, 4, p. 899-908 10 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Basic Genetics and Epigenetics of Childhood Lung Disease

    Wambach, J., Chaudhari, B. P. & Hamvas, A., Jan 1 2019, Kendig's Disorders of the Respiratory Tract in Children. Elsevier Inc, p. 40-48.e2

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care

    Chung, H. U., Kim, B. H., Lee, J. Y., Lee, J., Xie, Z., Ibler, E. M., Lee, K. H., Banks, A., Jeong, J. Y., Kim, J., Ogle, C., Grande, D., Yu, Y., Jang, H., Assem, P., Ryu, D., Kwak, J. W., Namkoong, M., Park, J. B., Lee, Y. & 25 others, Kim, D. H., Ryu, A., Jeong, J., You, K., Ji, B., Liu, Z., Huo, Q., Feng, X., Deng, Y., Xu, Y., Jang, K. I., Kim, J., Zhang, Y., Ghaffari, R., Rand, C. M., Schau, M., Hamvas, A., Weese-Mayer, D. E., Huang, Y., Lee, S. M., Lee, C. H., Shanbhag, N. R., Paller, A. S., Xu, S. & Rogers, J. A., Jan 1 2019, In : Science. 363, 6430

    Research output: Contribution to journalArticle

    Open Access
  • 55 Scopus citations

    Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia

    Prematurity and Respiratory Outcome Program (PROP) Investigators, Apr 2019, In : Journal of Pediatrics. 207, p. 130-135.e2

    Research output: Contribution to journalArticle

  • 8 Scopus citations