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Abdelhak Belmadani

  • 936 Citations
20012018
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Personal profile

Research Interests

My work seeks to understand how chemokines and their receptors regulate aspects of adult and embryonic neurogenesis. Translational aspects of this research concern the hope that neural stem cells can be directed by cytokines to conduct brain repair following trauma, stroke and neurodegenerative disease, such epilepsy. Techniques I mastered include mouse genetics, neuro-histology, neural stem cells and fluorescence imaging

Training Experience

2002Postdoctoral Fellowship, Loyola University

Education/Academic qualification

PhD, University Paris

… → 1998

Research interests

  • Brain Injury
  • Epilepsy
  • Nervous System Diseases
  • Neuroinflammation
  • Neurologic Complications of AIDS
  • Neuroscience
  • Schizophrenia
  • Stem Cells

Fingerprint Dive into the research topics where Abdelhak Belmadani is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Chemokines Medicine & Life Sciences
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Neurons Medicine & Life Sciences
Neural Stem Cells Medicine & Life Sciences
Nociceptors Medicine & Life Sciences
Sensory Receptor Cells Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2005 2018

Osteoarthritis Progression and Sensory Pathway Alterations

Belmadani, A. & Miller, R. J.

Rush University Medical Center, National Institute of Arthritis and Musculoskeletal and Skin Diseases

5/1/16 → 4/30/18

Project: Research project

Osteoarthritis Progression and Sensory Pathway Alterations

Belmadani, A. & Miller, R. J.

Rush University Medical Center, National Institute of Arthritis and Musculoskeletal and Skin Diseases

5/1/13 → 4/30/16

Project: Research project

Chemokine Receptor Function in the Nervous System

Belmadani, A. & Miller, R. J.

National Institute on Drug Abuse

7/15/11 → 4/30/17

Project: Research project

Chemokine Receptor Function in the Nervous System

Belmadani, A. & Miller, R. J.

National Institute on Drug Abuse

9/1/05 → 6/30/10

Project: Research project

Research Output 2001 2018

  • 936 Citations
  • 16 Article
  • 2 Comment/debate
  • 1 Review article
9 Citations (Scopus)

Reducing CXCR4-mediated nociceptor hyperexcitability reverses painful diabetic neuropathy

Jayaraj, N. D., Bhattacharyya, B. J., Belmadani, A. A., Ren, D., Rathwell, C. A., Hackelberg, S., Hopkins, B. E., Gupta, H. R., Miller, R. J. & Menichella, D. M., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2205-2225 21 p.

Research output: Contribution to journal › Article

Nociceptors
Diabetic Neuropathies
Spinal Ganglia
Hyperalgesia
Neurons
16 Citations (Scopus)

Directed differentiation of human embryonic stem cells toward placode-derived spiral ganglion-like sensory neurons

Matsuoka, A. J., Morrissey, Z. D., Zhang, C., Homma, K., Belmadani, A., Miller, C. A., Chadly, D. M., Kobayashi, S., Edelbrock, A. N., Tanaka-Matakatsu, M., Whitlon, D. S., Lyass, L., McGuire, T. L., Stupp, S. I. & Kessler, J. A., Mar 2017, In : Stem Cells Translational Medicine. 6, 3, p. 923-936 14 p.

Research output: Contribution to journal › Article

Spiral Ganglion
Sensory Receptor Cells
Neurons
Ear
Ectoderm
36 Citations (Scopus)

Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through toll-like receptor 4

Miller, R. E., Belmadani, A., Ishihara, S., Tran, P. B., Ren, D., Miller, R. J. & Malfait, A. M., Nov 1 2015, In : Arthritis and Rheumatology. 67, 11, p. 2933-2943 11 p.

Research output: Contribution to journal › Article

Nociceptors
Toll-Like Receptor 4
Osteoarthritis
Tibial Meniscus
Spinal Ganglia
9 Citations (Scopus)

Identification of a sustained neurogenic zone at the dorsal surface of the adult mouse hippocampus and its regulation by the chemokine SDF-1

Belmadani, A., Ren, D., Bhattacharyya, B. J., Rothwangl, K. B., Hope, T. J., Perlman, H. R. & Miller, R. J., Nov 1 2015, In : Hippocampus. 25, 11, p. 1224-1241 18 p.

Research output: Contribution to journal › Article

Dentate Gyrus
Chemokines
Hippocampus
Neural Stem Cells
CXCR4 Receptors
26 Citations (Scopus)

CXCR4 chemokine receptor signaling mediates pain in diabetic neuropathy

Menichella, D. M., Abdelhak, B., Ren, D., Shum, A., Frietag, C. & Miller, R. J., Jun 25 2014, In : Molecular Pain. 10, 1, 42.

Research output: Contribution to journal › Article

CXCR4 Receptors
Diabetic Neuropathies
Chemokine Receptors
Diagnosis-Related Groups
Pain