Research Output 2005 2018

2018

Introductory Overview of the Natural Experiments for Translation in Diabetes 2.0 (NEXT-D2) Network: Examining the Impact of US Health Policies and Practices to Prevent Diabetes and Its Complications

Duru, O. K., Mangione, C. M., Rodriguez, H. P., Ross-Degnan, D., Wharam, J. F., Black, B., Kho, A., Huguet, N., Angier, H., Mayer, V., Siscovick, D., Kraschnewski, J. L., Shi, L., Nauman, E., Gregg, E. W., Ali, M. K., Thornton, P. & Clauser, S. Feb 1 2018 In : Current Diabetes Reports. 18, 2, 8

Research output: Contribution to journalReview article

Diabetes Complications
Public Policy
Health Policy
Healthcare Financing
Incidence

Learning bundled care opportunities from electronic medical records

Chen, Y., Kho, A. N., Liebovitz, D., Ivory, C., Osmundson, S., Bian, J. & Malin, B. A. Jan 1 2018 In : Journal of Biomedical Informatics. 77, p. 1-10 10 p.

Research output: Contribution to journalArticle

Electronic medical equipment
Electronic Health Records
Health
Learning
Delivery of Health Care
2017

A computable phenotype for asthma case identification in adult and pediatric patients: External validation in the Chicago Area Patient-Outcomes Research Network (CAPriCORN)

Afshar, M., Press, V. G., Robison, R. G., Kho, A. N., Bandi, S., Biswas, A., Avila, P. C., Kumar, H. V. M., Yu, B., Naureckas, E. T., Nyenhuis, S. M. & Codispoti, C. D. Nov 10 2017 (Accepted/In press) In : Journal of Asthma. p. 1-8 8 p.

Research output: Contribution to journalArticle

Asthma
Outcome Assessment (Health Care)
Pediatrics
Electronic Health Records
Phenotype
4 Citations

Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans

Nadkarni, G. N., Galarneau, G., Ellis, S. B., Nadukuru, R., Zhang, J., Scott, S. A., Schurmann, C., Li, R., Rasmussen-Torvik, L. J., Kho, A. N., Hayes, M. G., Pacheco, J. A., Manolio, T. A., Chisholm, R. L., Roden, D. M., Denny, J. C., Kenny, E. E. & Bottinger, E. P. Mar 28 2017 In : Journal of the American College of Cardiology. 69, 12, p. 1564-1574 11 p.

Research output: Contribution to journalArticle

Apolipoproteins
African Americans
Blood Pressure
Alleles
Hypertension

Disease Outcomes and Care Fragmentation Among Patients With Systemic Lupus Erythematosus

Walunas, T. L., Jackson, K. L., Chung, A. H., Mancera-Cuevas, K. A., Erickson, D. L., Ramsey-Goldman, R. & Kho, A. Sep 1 2017 In : Arthritis Care and Research. 69, 9, p. 1369-1376 8 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
International Classification of Diseases
Odds Ratio
Confidence Intervals
Insurance
4 Citations

Distance from hospital impacts adverse event detection after outpatient endoscopy

Jackson, K. L., Goel, S., Kho, A. N. & Keswani, R. N. Feb 1 2017 In : Gastrointestinal Endoscopy. 85, 2, p. 380-386 7 p.

Research output: Contribution to journalArticle

Endoscopy
Outpatients
Mortality
Endoscopic Retrograde Cholangiopancreatography
Emergency Medical Services
6 Citations

Evolving use of seizure medications after intracerebral hemorrhage: A multicenter study

Naidech, A. M., Beaumont, J., Jahromi, B., Prabhakaran, S., Kho, A. & Holl, J. L. Jan 3 2017 In : Neurology. 88, 1, p. 52-56 5 p.

Research output: Contribution to journalArticle

etiracetam
Cerebral Hemorrhage
Multicenter Studies
Seizures
Guidelines
2 Citations

Genome-wide study of resistant hypertension identified from electronic health records

Dumitrescu, L. , Ritchie, M. D. , Denny, J. C. , Rouby, N. M. E. , McDonough, C. W. , Bradford, Y. , Ramirez, A. H. , Bielinski, S. J. , Basford, M. A. , Chai, H. S. , Peissig, P. , Carrell, D. , Pathak, J. , Rasmussen, L. V. , Wang, X. , Pacheco, J. A. , Kho, A. N. , Hayes, M. G. , Matsumoto, M. , Smith, M. E. & 15 others Li, R., Cooper-DeHoff, R. M., Kullo, I. J., Chute, C. G., Chisholm, R. L., Jarvik, G. P., Larson, E. B., Carey, D., McCarty, C. A., Williams, M. S., Roden, D. M., Bottinger, E., Johnson, J. A., De Andrade, M. & Crawford, D. C. Feb 1 2017 In : PLoS ONE. 12, 2, e0171745

Research output: Contribution to journalArticle

Electronic Health Records
hypertension
electronics
Genes
Blood pressure

Granite: Diversified, Sparse Tensor Factorization for Electronic Health Record-Based Phenotyping

Henderson, J., Ho, J. C., Kho, A. N., Denny, J. C., Malin, B. A., Sun, J. & Ghosh, J. Sep 8 2017 Proceedings - 2017 IEEE International Conference on Healthcare Informatics, ICHI 2017. Institute of Electrical and Electronics Engineers Inc., p. 214-223 10 p. 8031150

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Electronic Health Records
Phenotype
granite
Artifacts
Population
1 Citations
End Stage Liver Disease
Electronic Health Records
Fibrosis
Sodium
Transplants

The building blocks of inter-operability: A multisite analysis of patient demographic attributes available for matching

Culbertson, A. , Goel, S. , Madden, M. B. , Safaeinili, N. , Jackson, K. L. , Carton, T. , Waitman, R. , Liu, M. , Krishnamurthy, A. , Hall, L. , Cappella, N. , Visweswaran, S. , Becich, M. J. , Applegate, R. , Bernstam, E. , Rothman, R. , Matheny, M. , Lipori, G. , Bian, J. , Hogan, W. & 7 others Bell, D., Martin, A., Grannis, S., Klann, J., Sutphen, R., O’Hara, A. B. & Kho, A. Jan 1 2017 In : Applied Clinical Informatics. 8, 2, p. 322-336 15 p.

Research output: Contribution to journalArticle

Interoperability
Demography
Availability
Names
Electronic mail
1 Citations

Validity of cardiovascular data from electronic sources: The multi-ethnic study of atherosclerosis and HealthLNK

Ahmad, F. S., Chan, C., Rosenman, M. B., Post, W. S., Fort, D. G., Greenland, P., Liu, K. J., Kho, A. N. & Allen, N. B. Sep 1 2017 In : Circulation. 136, 13, p. 1207-1216 10 p.

Research output: Contribution to journalArticle

Information Storage and Retrieval
Atherosclerosis
Blood Pressure
Body Mass Index
International Classification of Diseases
2016
4 Citations

An evaluation of recurrent diabetic ketoacidosis, fragmentation of care, and mortality across Chicago, Illinois

Mays, J. A., Jackson, K. L., Derby, T. A., Behrens, J. J., Goel, S., Molitch, M. E., Kho, A. N. & Wallia, A. Oct 1 2016 In : Diabetes Care. 39, 10, p. 1671-1676 6 p.

Research output: Contribution to journalArticle

Diabetic Ketoacidosis
Mortality
International Classification of Diseases
Odds Ratio
Health Insurance Portability and Accountability Act
8 Citations

A survey of clinical phenotyping in selected national networks: demonstrating the need for high-throughput, portable, and computational methods

Richesson, R. L., Sun, J., Pathak, J., Kho, A. N. & Denny, J. C. Jul 1 2016 In : Artificial Intelligence in Medicine. 71, p. 57-61 5 p.

Research output: Contribution to journalArticle

Precision Medicine
Computational methods
Medicine
Throughput
Phenotype
2 Citations

Communicating Chaplains’ Care: Narrative Documentation in a Neuroscience-Spine Intensive Care Unit

Johnson, R., Wirpsa, M. J., Boyken, L., Sakumoto, M., Handzo, G., Kho, A. & Emanuel, L. Oct 1 2016 In : Journal of Health Care Chaplaincy. 22, 4, p. 133-150 18 p.

Research output: Contribution to journalArticle

Clergy
Patient Care Team
Neurosciences
neurosciences
Documentation
9 Citations

CommunityRx: A population health improvement innovation that connects clinics to communities

Lindau, S. T., Makelarski, J., Abramsohn, E., Beiser, D. G., Escamilla, V., Jerome, J., Johnson, D., Kho, A. N., Lee, K. K., Long, T. & Miller, D. C. Jan 1 2016 In : Health Affairs. 35, 11, p. 2020-2029 10 p.

Research output: Contribution to journalArticle

Medical Informatics
Health
Population
Health Manpower
Information Services
Electronic Health Records
Ophthalmology
Visual Acuity
Research
7 Citations

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium

Verma, S. S. , Cooke Bailey, J. N. , Lucas, A. , Bradford, Y. , Linneman, J. G. , Hauser, M. A. , Pasquale, L. R. , Peissig, P. L. , Brilliant, M. H. , McCarty, C. A. , Haines, J. L. , Wiggs, J. L. , Vrabec, T. R. , Tromp, G. , Ritchie, M. D. , Bickel, J. , Chandler, A. , Holm, I. , Kohane, I. , Manzi, S. & 32 others Markianos, K., Palmer, N., Perry, C., Savova, G., Wolf, W., Wong Kong, S., Antommaria, A., Cobb, B., Harley, J., Hutton, J., Lingren, T., Lynch, J., Marsolo, K., Myers, M., Namjou, B., Prows, C., Solti, I., Vinks, S., Baker, D., Chisholm, R., Christensen, C., Hayes, G., Heathcote, M., Lowe, B., Rasmussen, L., Smith, M., Starren, J., Thompson, W., Wicklund, C., Brothers, K., eMERGE Network & NEIGHBOR Consortium Sep 1 2016 In : PLoS Genetics. 12, 9, e1006186

Research output: Contribution to journalArticle

Genetic Epistasis
glaucoma
Electronic Health Records
epistasis
Genomics
1 Citations

Performance of an electronic health record-based phenotype algorithm to identify community associated methicillin-resistant Staphylococcus aureus cases and controls for genetic association studies

Jackson, K. L., Mbagwu, M., Pacheco, J. A., Baldridge, A. S., Viox, D. J., Linneman, J. G., Shukla, S. K., Peissig, P. L., Borthwick, K. M., Carrell, D. A., Bielinski, S. J., Kirby, J. C., Denny, J. C., Mentch, F. D., Vazquez, L. M., Rasmussen-Torvik, L. J. & Kho, A. N. Nov 17 2016 In : BMC Infectious Diseases. 16, 1, 684

Research output: Contribution to journalArticle

Electronic Health Records
Genetic Association Studies
Methicillin-Resistant Staphylococcus aureus
Phenotype
Genome-Wide Association Study
1 Citations

SMCQL: Secure querying for federated databases

Bater, J., Goel, S., Elliott, G., Kho, A., Eggen, C. & Rogers, J. Jan 1 2016 In : Proceedings of the VLDB Endowment. 10, 6, p. 673-684 12 p.

Research output: Contribution to journalArticle

Data storage equipment
Industry
12 Citations

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

Liu, C. T. , Raghavan, S. , Maruthur, N. , Kabagambe, E. K. , Hong, J. , Ng, M. C. Y. , Hivert, M. F. , Lu, Y. , An, P. , Bentley, A. R. , Drolet, A. M. , Gaulton, K. J. , Guo, X. , Armstrong, L. L. , Irvin, M. R. , Li, M. , Lipovich, L. , Rybin, D. V. , Taylor, K. D. , Agyemang, C. & 95 others Palmer, N. D., Cade, B. E., Chen, W. M., Dauriz, M., Delaney, J. A. C., Edwards, T. L., Evans, D. S., Evans, M. K., Lange, L. A., Leong, A., Liu, J., Liu, Y., Nayak, U., Patel, S. R., Porneala, B. C., Rasmussen-Torvik, L. J., Snijder, M. B., Stallings, S. C., Tanaka, T., Yanek, L. R., Zhao, W., Becker, D. M., Bielak, L. F., Biggs, M. L., Bottinger, E. P., Bowden, D. W., Chen, G., Correa, A., Couper, D. J., Crawford, D. C., Cushman, M., Eicher, J. D., Fornage, M., Franceschini, N., Fu, Y. P., Goodarzi, M. O., Gottesman, O., Hara, K., Harris, T. B., Jensen, R. A., Johnson, A. D., Jhun, M. A., Karter, A. J., Keller, M. F., Kho, A. N., Kizer, J. R., Krauss, R. M., Langefeld, C. D., Li, X., Liang, J., Liu, S., Lowe, W. L., Mosley, T. H., North, K. E., Pacheco, J. A., Peyser, P. A., Patrick, A. L., Rice, K. M., Selvin, E., Sims, M., Smith, J. A., Tajuddin, S. M., Vaidya, D., Wren, M. P., Yao, J., Zhu, X., Ziegler, J. T., Zmuda, J. M., Zonderman, A. B., Zwinderman, A. H., Adeyemo, A., Boerwinkle, E., Ferrucci, L., Hayes, M. G., Kardia, S. L. R., Miljkovic, I., Pankow, J. S., Rotimi, C. N., Sale, M. M., Wagenknecht, L. E., Arnett, D. K., Chen, Y. D. I., Nalls, M. A., Province, M. A., Kao, W. H. L., Siscovick, D. S., Psaty, B. M., Wilson, J. G., Loos, R. J. F., Dupuis, J., Rich, S. S., Florez, J. C., Rotter, J. I., Morris, A. P. & Meigs, J. B. Jul 7 2016 In : American Journal of Human Genetics. 99, 1, p. 56-75 20 p.

Research output: Contribution to journalArticle

Meta-Analysis
Fasting
Insulin
Glucose
Type 2 Diabetes Mellitus

Using Monte Carlo/Gaussian Based Small Area Estimates to Predict Where Medicaid Patients Reside

Behrens, J. J., Wen, X., Goel, S., Zhou, J., Fu, L. & Kho, A. N. Jan 1 2016 In : AMIA ... Annual Symposium proceedings. AMIA Symposium. 2016, p. 305-309 5 p.

Research output: Contribution to journalArticle

Electronic Health Records
Medicaid
Population
Health
2015
2 Citations
Public Policy
Delivery of Health Care
Electronic Health Records
Health
Physiologic Monitoring
9 Citations

Building bridges across electronic health record systems through inferred phenotypic topics

Chen, Y., Ghosh, J., Bejan, C. A., Gunter, C. A., Gupta, S., Kho, A., Liebovitz, D., Sun, J., Denny, J. & Malin, B. Jun 1 2015 In : Journal of Biomedical Informatics. 55, p. 82-93 12 p.

Research output: Contribution to journalArticle

Electronic Health Records
Health
Terminology
Population
Delivery of Health Care
16 Citations

Design and implementation of a privacy preserving electronic health record linkage tool in Chicago

Kho, A. N., Cashy, J. P., Jackson, K. L., Pah, A. R., Goel, S., Boehnke, J., Humphries, J. E., Kominers, S. D., Hota, B. N., Sims, S. A., Malin, B. A., French, D. D., Walunas, T. L., Meltzer, D. O., Kaleba, E. O., Jones, R. C. & Galanter, W. L. Jan 1 2015 In : Journal of the American Medical Informatics Association. 22, 5, p. 1072-1080 9 p.

Research output: Contribution to journalArticle

Electronic Health Records
Privacy
Software
Research
Health Insurance Portability and Accountability Act
13 Citations

Genetic variation in the HLA region is associated with susceptibility to herpes zoster

Crosslin, D. R. , Carrell, D. S. , Burt, A. , Kim, D. S. , Underwood, J. G. , Hanna, D. S. , Comstock, B. A. , Baldwin, E. , De Andrade, M. , Kullo, I. J. , Tromp, G. , Kuivaniemi, H. , Borthwick, K. M. , McCarty, C. A. , Peissig, P. L. , Doheny, K. F. , Pugh, E. , Kho, A. , Pacheco, J. , Hayes, M. G. & 17 others Ritchie, M. D., Verma, S. S., Armstrong, G., Stallings, S., Denny, J. C., Carroll, R. J., Crawford, D. C., Crane, P. K., Mukherjee, S., Bottinger, E., Li, R., Keating, B., Mirel, D. B., Carlson, C. S., Harley, J. B., Larson, E. B. & Jarvik, G. P. Jan 24 2015 In : Genes and Immunity. 16, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Herpes Zoster
Human Herpesvirus 3
Herpes Zoster Vaccine
Endogenous Retroviruses
Nerve Tissue
2 Citations

Patient-Centered Outcomes Research in Practice: The CAPriCORN Infrastructure

Solomonides, A. , Goel, S. , Hynes, D. , Silverstein, J. C. , Hota, B. , Trick, W. , Angulo, F. , Price, R. , Sadhu, E. , Zelisko, S. , Fischer, J. , Furner, B. , Hamilton, A. , Phua, J. , Brown, W. , Hohmann, S. F. , Meltzer, D. , Tarlov, E. , Weaver, F. M. , Zhang, H. & 2 others Concannon, T. & Kho, A. Jan 1 2015 MEDINFO 2015: eHealth-Enabled Health - Proceedings of the 15th World Congress on Health and Biomedical Informatics. IOS Press, p. 584-588 5 p. (Studies in Health Technology and Informatics; vol. 216)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Patient Outcome Assessment
Health
Sampling
Communication
Sampling Studies
37 Citations

Rubik: Knowledge guided tensor factorization and completion for health data analytics

Wang, Y., Chen, R., Ghosh, J., Denny, J. C., Kho, A., Chen, Y., Malin, B. A. & Sun, J. Aug 10 2015 KDD 2015 - Proceedings of the 21st ACM SIGKDD Conference on Knowledge Discovery and Data Mining. Association for Computing Machinery, Vol. 2015-August, p. 1265-1274 10 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Factorization
Tensors
Health
Parallel processing systems
2014
9 Citations

Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans

Jeff, J. M., Armstrong, L. L., Ritchie, M. D., Denny, J. C., Kho, A. N., Basford, M. A., Wolf, W. A., Pacheco, J. A., Li, R., Chisholm, R. L., Roden, D. M., Geoffrey Hayes, M. & Crawford, D. C. Mar 3 2014 In : PLoS ONE. 9, 3, e86931

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 2
African Americans
Chromosomes
Medical problems
53 Citations

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

Shameer, K., Denny, J. C., Ding, K., Jouni, H., Crosslin, D. R., De Andrade, M., Chute, C. G., Peissig, P., Pacheco, J. A., Li, R., Bastarache, L., Kho, A. N., Ritchie, M. D., Masys, D. R., Chisholm, R. L., Larson, E. B., McCarty, C. A., Roden, D. M., Jarvik, G. P. & Kullo, I. J. Jan 1 2014 In : Human Genetics. 133, 1, p. 95-109 15 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Platelet Count
Mean Platelet Volume
Blood Platelets
Single Nucleotide Polymorphism
13 Citations

Anatomic and advanced adenoma detection rates as quality metrics determined via natural language processing

Gawron, A. J., Thompson, W. K., Keswani, R. N., Rasmussen, L. V. & Kho, A. N. Jan 1 2014 In : American Journal of Gastroenterology. 109, 12, p. 1844-1849 6 p.

Research output: Contribution to journalArticle

Natural Language Processing
Adenoma
Colonoscopy
Colon
Nonparametric Statistics
5 Citations

A rigorous algorithm to detect and clean inaccurate adult height records within EHR systems

Muthalagu, A., Pacheco, J. A., Aufox, S., Peissig, P. L., Fuehrer, J. T., Tromp, G., Kho, A. N. & Rasmussen-Torvik, L. J. Jan 1 2014 In : Applied Clinical Informatics. 5, 1, p. 118-126 9 p.

Research output: Contribution to journalArticle

Body Mass Index
Cleaning
Research
Software
Aging of materials
13 Citations

CAPriCORN: Chicago area patient-centered outcomes research network

Kho, A. N. , Hynes, D. M. , Goel, S. , Solomonides, A. E. , Price, R. , Hota, B. , Sims, S. A. , Bahroos, N. , Angulo, F. , Trick, W. E. , Tarlov, E. , Rachman, F. D. , Hamilton, A. , Kaleba, E. O. , Badlani, S. , Volchenboum, S. L. , Silverstein, J. C. , Tobin, J. N. , Schwartz, M. A. , Levine, D. & 6 others Wong, J. B., Kennedy, R. H., Krishnan, J. A., Meltzer, D. O., Collins, J. M. & Mazany, T. Jan 1 2014 In : Journal of the American Medical Informatics Association. 21, 4, p. 607-611 5 p.

Research output: Contribution to journalArticle

Patient Outcome Assessment
Health
Comparative Effectiveness Research
Delivery of Health Care
Veterans Hospitals
494 Citations

Defining the role of common variation in the genomic and biological architecture of adult human height

Wood, A. R. , Esko, T. , Yang, J. , Vedantam, S. , Pers, T. H. , Gustafsson, S. , Chu, A. Y. , Estrada, K. , Luan, J. A. , Kutalik, Z. , Amin, N. , Buchkovich, M. L. , Croteau-Chonka, D. C. , Day, F. R. , Duan, Y. , Fall, T. , Fehrmann, R. , Ferreira, T. , Jackson, A. U. , Karjalainen, J. & 425 others Lo, K. S., Locke, A. E., Mägi, R., Mihailov, E., Porcu, E., Randall, J. C., Scherag, A., Vinkhuyzen, A. A. E., Westra, H. J., Winkler, T. W., Workalemahu, T., Zhao, J. H., Absher, D., Albrecht, E., Anderson, D., Baron, J., Beekman, M., Demirkan, A., Ehret, G. B., Feenstra, B., Feitosa, M. F., Fischer, K., Fraser, R. M., Goel, A., Gong, J., Justice, A. E., Kanoni, S., Kleber, M. E., Kristiansson, K., Lim, U., Lotay, V., Lui, J. C., Mangino, M., Leach, I. M., Medina-Gomez, C., Nalls, M. A., Nyholt, D. R., Palmer, C. D., Pasko, D., Pechlivanis, S., Prokopenko, I., Ried, J. S., Ripke, S., Shungin, D., Stancáková, A., Strawbridge, R. J., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., Van Der Laan, S. W., Van Setten, J., Van Vliet-Ostaptchouk, J. V., Wang, Z., Yengo, L., Zhang, W., Afzal, U., Ärnlöv, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blüher, M., Bolton, J. L., Böttcher, Y., Boyd, H. A., Bruinenberg, M., Buckley, B. M., Buyske, S., Caspersen, I. H., Chines, P. S., Clarke, R., Claudi-Boehm, S., Cooper, M., Daw, E. W., De Jong, P. A., Deelen, J., Delgado, G., Denny, J. C., Dhonukshe-Rutten, R., Dimitriou, M., Doney, A. S. F., Dörr, M., Eklund, N., Eury, E., Folkersen, L., Garcia, M. E., Geller, F., Giedraitis, V., Go, A. S., Grallert, H., Grammer, T. B., Gräßler, J., Grönberg, H., De Groot, L. C. P. G. M., Groves, C. J., Haessler, J., Hall, P., Haller, T., Hallmans, G., Hannemann, A., Hartman, C. A., Hassinen, M., Hayward, C., Heard-Costa, N. L., Helmer, Q., Hemani, G., Henders, A. K., Hillege, H. L., Hlatky, M. A., Hoffmann, W., Hoffmann, P., Holmen, O., Houwing-Duistermaat, J. J., Illig, T., Isaacs, A., James, A. L., Jeff, J., Johansen, B., Johansson, Å., Jolley, J., Juliusdottir, T., Junttila, J., Kho, A. N., Kinnunen, L., Klopp, N., Kocher, T., Kratzer, W., Lichtner, P., Lind, L., Lindström, J., Lobbens, S., Lorentzon, M., Lu, Y., Lyssenko, V., Magnusson, P. K. E., Mahajan, A., Maillard, M., McArdle, W. L., McKenzie, C. A., McLachlan, S., McLaren, P. J., Menni, C., Merger, S., Milani, L., Moayyeri, A., Monda, K. L., Morken, M. A., Müller, G., Müller-Nurasyid, M., Musk, A. W., Narisu, N., Nauck, M., Nolte, I. M., Nöthen, M. M., Oozageer, L., Pilz, S., Rayner, N. W., Renstrom, F., Robertson, N. R., Rose, L. M., Roussel, R., Sanna, S., Scharnagl, H., Scholtens, S., Schumacher, F. R., Schunkert, H., Scott, R. A., Sehmi, J., Seufferlein, T., Shi, J., Silventoinen, K., Smit, J. H., Smith, A. V., Smolonska, J., Stanton, A. V., Stirrups, K., Stott, D. J., Stringham, H. M., Sundström, J., Swertz, M. A., Syvänen, A. C., Tayo, B. O., Thorleifsson, G., Tyrer, J. P., Van Dijk, S., Van Schoor, N. M., Van Der Velde, N., Van Heemst, D., Van Oort, F. V. A., Vermeulen, S. H., Verweij, N., Vonk, J. M., Waite, L. L., Waldenberger, M., Wennauer, R., Wilkens, L. R., Willenborg, C., Wilsgaard, T., Wojczynski, M. K., Wong, A., Wright, A. F., Zhang, Q., Arveiler, D., Bakker, S. J. L., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boomsma, D. I., Bornstein, S. R., Bovet, P., Brambilla, P., Brown, M. J., Campbell, H., Caulfield, M. J., Chakravarti, A., Collins, R., Collins, F. S., Crawford, D. C., Cupples, L. A., Danesh, J., De Faire, U., Den Ruijter, H. M., Erbel, R., Erdmann, J., Eriksson, J. G., Farrall, M., Ferrannini, E., Ferrières, J., Ford, I., Forouhi, N. G., Forrester, T., Gansevoort, R. T., Gejman, P. V., Gieger, C., Golay, A., Gottesman, O., Gudnason, V., Gyllensten, U., Haas, D. W., Hall, A. S., Harris, T. B., Hattersley, A. T., Heath, A. C., Hengstenberg, C., Hicks, A. A., Hindorff, L. A., Hingorani, A. D., Hofman, A., Hovingh, G. K., Humphries, S. E., Hunt, S. C., Hypponen, E., Jacobs, K. B., Jarvelin, M. R., Jousilahti, P., Jula, A. M., Kaprio, J., Kastelein, J. J. P., Kayser, M., Kee, F., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kooner, J. S., Kooperberg, C., Koskinen, S., Kovacs, P., Kraja, A. T., Kumari, M., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lupoli, S., Madden, P. A. F., Männistö, S., Manunta, P., Marette, A., Matise, T. C., McKnight, B., Meitinger, T., Moll, F. L., Montgomery, G. W., Morris, A. D., Morris, A. P., Murray, J. C., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Ouwehand, W. H., Pasterkamp, G., Peters, A., Pramstaller, P. P., Price, J. F., Qi, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ritchie, M., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schwarz, P. E. H., Sebert, S., Sever, P., Shuldiner, A. R., Sinisalo, J., Steinthorsdottir, V., Stolk, R. P., Tardif, J. C., Tönjes, A., Tremblay, A., Tremoli, E., Virtamo, J., Vohl, M. C., Amouyel, P., Asselbergs, F. W., Assimes, T. L., Bochud, M., Boehm, B. O., Boerwinkle, E., Bottinger, E. P., Bouchard, C., Cauchi, S., Chambers, J. C., Chanock, S. J., Cooper, R. S., De Bakker, P. I. W., Dedoussis, G., Ferrucci, L., Franks, P. W., Froguel, P., Groop, L. C., Haiman, C. A., Hamsten, A., Hayes, M. G., Hui, J., Hunter, D. J., Hveem, K., Jukema, J. W., Kaplan, R. C., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Martin, N. G., März, W., Melbye, M., Moebus, S., Munroe, P. B., Njølstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Pérusse, L., Peters, U., Powell, J. E., Power, C., Quertermous, T., Rauramaa, R., Reinmaa, E., Ridker, P. M., Rivadeneira, F., Rotter, J. I., Saaristo, T. E., Saleheen, D., Schlessinger, D., Slagboom, P. E., Snieder, H., Spector, T. D., Strauch, K., Stumvoll, M., Tuomilehto, J., Uusitupa, M., Van Der Harst, P., Völzke, H., Walker, M., Wareham, N. J., Watkins, H., Wichmann, H. E., Wilson, J. F., Zanen, P., Deloukas, P., Heid, I. M., Lindgren, C. M., Mohlke, K. L., Speliotes, E. K., Thorsteinsdottir, U., Barroso, I., Fox, C. S., North, K. E., Strachan, D. P., Beckmann, J. S., Berndt, S. I., Boehnke, M., Borecki, I. B., McCarthy, M. I., Metspalu, A., Stefansson, K., Uitterlinden, A. G., Van Duijn, C. M., Franke, L., Willer, C. J., Price, A. L., Lettre, G., Loos, R. J. F., Weedon, M. N., Ingelsson, E., O'Connell, J. R., Abecasis, G. R., Chasman, D. I., Goddard, M. E., Visscher, P. M., Hirschhorn, J. N. & Frayling, T. M. Nov 5 2014 In : Nature Genetics. 46, 11, p. 1173-1186 14 p.

Research output: Contribution to journalArticle

Genes
Genome
Catenins
Fibroblast Growth Factors
Chondroitin Sulfates
11 Citations

Design patterns for the development of electronic health record-driven phenotype extraction algorithms

Rasmussen, L. V., Thompson, W. K., Pacheco, J. A., Kho, A. N., Carrell, D. S., Pathak, J., Peissig, P. L., Tromp, G., Denny, J. C. & Starren, J. B. Jan 1 2014 In : Journal of Biomedical Informatics. 51, p. 280-286 7 p.

Research output: Contribution to journalArticle

Electronic Health Records
Health
Phenotype
Knowledge Bases
Electronic medical equipment
10 Citations

Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network

Malinowski, J. R. , Denny, J. C. , Bielinski, S. J. , Basford, M. A. , Bradford, Y. , Peissig, P. L. , Carrell, D. , Crosslin, D. R. , Pathak, J. , Rasmussen, L. , Pacheco, J. , Kho, A. , Newton, K. M. , Li, R. , Kullo, I. J. , Chute, C. G. , Chisholm, R. L. , Jarvik, G. P. , Larson, E. B. , McCarty, C. A. & 5 others Masys, D. R., Roden, D. M., De Andrade, M., Ritchie, M. D. & Crawford, D. C. Dec 1 2014 In : PLoS ONE. 9, 12, e111301

Research output: Contribution to journalArticle

Electronic medical equipment
thyrotropin
Electronic Health Records
Thyrotropin
African Americans
60 Citations

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

Ng, M. C. Y. , Shriner, D. , Chen, B. H. , Li, J. , Chen, W. M. , Guo, X. , Liu, J. , Bielinski, S. J. , Yanek, L. R. , Nalls, M. A. , Comeau, M. E. , Rasmussen-Torvik, L. J. , Jensen, R. A. , Evans, D. S. , Sun, Y. V. , An, P. , Patel, S. R. , Lu, Y. , Long, J. , Armstrong, L. L. & 32 others Wagenknecht, L., Yang, L., Snively, B. M., Palmer, N. D., Mudgal, P., Langefeld, C. D., Keene, K. L., Freedman, B. I., Mychaleckyj, J. C., Nayak, U., Raffel, L. J., Goodarzi, M. O., Chen, Y. D. I., Taylor, H. A., Correa, A., Sims, M., Couper, D., Pankow, J. S., Boerwinkle, E., Adeyemo, A., Doumatey, A., Hayes, M. G., Starren, J., Chisholm, R. L., Greenland, P., Kho, A. N., Lowe, W. L., Smith, M. E., Thompson, W. K., Cornelis, M., The MAGIC investigators & The GIANT consortium Aug 7 2014 In : PLoS genetics. 10, 8, e1004517

Research output: Contribution to journalArticle

diabetes
African American
Genome-Wide Association Study
meta-analysis
African Americans
3 Citations

Nascent regional system for alerting infection preventionists about patients with multidrug-resistant gram-negative bacteria: Implementation and initial results

Rosenman, M. B., Szucs, K. A., Finnell, S. M. E., Khokhar, S., Egg, J., Lemmon, L., Shepherd, D. C., Friedlin, J., Li, X. & Kho, A. N. Jan 1 2014 In : Infection Control and Hospital Epidemiology. 35, p. S40-S47

Research output: Contribution to journalArticle

Gram-Negative Bacteria
Microbiology
Infection
Enterobacteriaceae
Hospital Emergency Service

Replication of SCN5A associations with electrocardiographic traits in African Americans from clinical and epidemiologic studies

Jeff, J. M. , Brown-Gentry, K. , Goodloe, R. , Ritchie, M. D. , Denny, J. C. , Kho, A. N. , Armstrong, L. L. , McClellan, B. , Mayo, P. , Allen, M. , Jin, H. , Gillani, N. B. , Schnetz-Boutaud, N. , Dilks, H. H. , Basford, M. A. , Pacheco, J. A. , Jarvik, G. P. , Chisholm, R. L. , Roden, D. M. , Geoffrey Haye, M. & 1 others Crawford, D. C. Jan 1 2014 Applications of Evolutionary Computation - 17th European Conference, EvoApplications 2014, Revised Selected Papers. Springer Verlag, p. 939-951 13 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8602)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Electronic medical equipment
Replication
Nutrition
Electrocardiography
Metaanalysis
4 Citations

Silence in the EHR: Infrequent documentation of aphonia in the electronic health record

Morris, M. A. & Kho, A. N. Sep 23 2014 In : BMC health services research. 14, 1, 425

Research output: Contribution to journalArticle

Aphonia
Electronic Health Records
Documentation
Communication Disorders
Communication

Use of herbal supplements with undeclared drug ingredients masking giant cell arteritis

Mbagwu, M. C., Weisman, P. S. & Kho, A. N. Jan 1 2014 In : Journal of Clinical Rheumatology. 20, 1, p. 51-53 3 p.

Research output: Contribution to journalArticle

Plant Preparations
Phytotherapy
Temporal Arteries
Giant Cell Arteritis
Delayed Diagnosis
2013
12 Citations

A regional informatics platform for coordinated antibiotic-resistant infection tracking, alerting, and prevention

Kho, A. N., Doebbeling, B. N., Cashy, J. P., Rosenman, M. B., Dexter, P. R., Shepherd, D. C., Lemmon, L., Teal, E., Khokar, S. & Overhage, J. M. Jul 15 2013 In : Clinical Infectious Diseases. 57, 2, p. 254-262 9 p.

Research output: Contribution to journalArticle

Informatics
Anti-Bacterial Agents
Infection
Registries
Methicillin-Resistant Staphylococcus aureus
57 Citations

Electronic health records-driven phenotyping: Challenges, recent advances, and perspectives

Pathak, J., Kho, A. N. & Denny, J. C. Dec 23 2013 In : Journal of the American Medical Informatics Association. 20, E2

Research output: Contribution to journalEditorial

Electronic Health Records
Genetic Association Studies
Genomics
Phenotype
20 Citations

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans

Jeff, J. M., Ritchie, M. D., Denny, J. C., Kho, A. N., Ramirez, A. H., Crosslin, D., Armstrong, L., Basford, M. A., Wolf, W. A., Pacheco, J. A., Chisholm, R. L., Roden, D. M., Hayes, M. G. & Crawford, D. C. Apr 2 2013 In : Annals of human genetics. 77, 4, p. 321-332 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
African Americans
Population
Heart Rate
Electronic Health Records
15 Citations

Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: An electronic medical record-based genome-wide association study

Ding, K., Andrade, M. D., Manolio, T. A., Crawford, D. C., Rasmussen-Torvik, L. J., Ritchie, M. D., Denny, J. C., Masys, D. R., Jouni, H., Pachecho, J. A., Kho, A. N., Roden, D. M., Chisholm, R. & Kullo, I. J. Jan 1 2013 In : G3: Genes, Genomes, Genetics. 3, 7, p. 1061-1068 8 p.

Research output: Contribution to journalArticle

Erythrocyte Indices
Electronic Health Records
Genome-Wide Association Study
African Americans
Malaria
29 Citations

Genetic variation associated with circulating monocyte count in the eMERGE Network

Crosslin, D. R. , McDavid, A. , Weston, N. , Zheng, X. , Hart, E. , de Andrade, M. , Kullo, I. J. , McCarty, C. A. , Doheny, K. F. , Pugh, E. , Kho, A. , Hayes, M. G. , Ritchie, M. D. , Saip, A. , Crawford, D. C. , Crane, P. K. , Newton, K. , Carrell, D. S. , Gallego, C. J. , Nalls, M. A. & 44 others Li, R., Mirel, D. B., Crenshaw, A., Couper, D. J., Tanaka, T., van Rooij, F. J. A., Chen, M. H., Smith, A. V., Zakai, N. A., Yango, Q., Garcia, M., Liu, Y., Lumley, T., Folsom, A. R., Reiner, A. P., Felix, J. F., Dehghan, A., Wilson, J. G., Bis, J. C., Fox, C. S., Glazer, N. L., Cupples, L. A., Coresh, J., Eiriksdottir, G., Gudnason, V., Bandinelli, S., Frayling, T. M., Chakravarti, A., van Duijn, C. M., Melzer, D., Levy, D., Boerwinkle, E., Singleton, A. B., Hernandez, D. G., Longo, D. L., Witteman, J. C. M., Psaty, B. M., Ferrucci, L., Harris, T. B., O'Donnell, C. J., Ganesh, S. K., Larson, E. B., Carlson, C. S. & Jarvik, G. P. May 1 2013 In : Human molecular genetics. 22, 10, p. 2119-2127 9 p.

Research output: Contribution to journalArticle

Monocytes
Genes
Joints
Lysophosphatidic Acid Receptors
Integrin alpha Chains
86 Citations

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk

Ritchie, M. D. , Denny, J. C. , Zuvich, R. L. , Crawford, D. C. , Schildcrout, J. S. , Bastarache, L. , Ramirez, A. H. , Mosley, J. D. , Pulley, J. M. , Basford, M. A. , Bradford, Y. , Rasmussen, L. V. , Pathak, J. , Chute, C. G. , Kullo, I. J. , Mccarty, C. A. , Chisholm, R. L. , Kho, A. N. , Carlson, C. S. , Larson, E. B. & 7 others Jarvik, G. P., Sotoodehnia, N., Manolio, T. A., Li, R., Masys, D. R., Haines, J. L. & Roden, D. M. Apr 2 2013 In : Circulation. 127, 13, p. 1377-1385 9 p.

Research output: Contribution to journalArticle

Electronic Health Records
Cardiac Arrhythmias
Genome
Genomics
Genome-Wide Association Study
7 Citations

Migration of patients between five urban teaching hospitals in Chicago

Galanter, W. L., Applebaum, A., Boddipalli, V., Kho, A., Lin, M., Meltzer, D., Roberts, A., Trick, B., Walton, S. M. & Lambert, B. L. Apr 1 2013 In : Journal of medical systems. 37, 2, 9930

Research output: Contribution to journalArticle

Urban Hospitals
Teaching Hospitals
Teaching
Mothers
Patient Discharge
2 Citations

Multihospital infection prevention collaborative: informatics challenges and strategies to prevent MRSA.

Doebbeling, B. N., Flanagan, M. E., Nall, G., Hoke, S., Rosenman, M. & Kho, A. Jan 1 2013 In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2013, p. 317-325 9 p.

Research output: Contribution to journalArticle

Informatics
Methicillin-Resistant Staphylococcus aureus
Infection
Information Storage and Retrieval
Ontario
27 Citations

Practical challenges in integrating genomic data into the electronic health record

Kho, A. N., Rasmussen, L. V., Connolly, J. J., Peissig, P. L., Starren, J., Hakonarson, H. & Hayes, M. G. Oct 1 2013 In : Genetics in Medicine. 15, 10, p. 772-778 7 p.

Research output: Contribution to journalReview article

Electronic Health Records
Genetic Testing
Privacy
Uncertainty