Research Output 2005 2018

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2018

Learning bundled care opportunities from electronic medical records

Chen, Y., Kho, A. N., Liebovitz, D., Ivory, C., Osmundson, S., Bian, J. & Malin, B. A. Jan 1 2018 In : Journal of Biomedical Informatics. 77, p. 1-10 10 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Learning
Health
Electronic medical equipment
Delivery of Health Care
2017

A computable phenotype for asthma case identification in adult and pediatric patients: External validation in the Chicago Area Patient-Outcomes Research Network (CAPriCORN)

Afshar, M., Press, V. G., Robison, R. G., Kho, A. N., Bandi, S., Biswas, A., Avila, P. C., Kumar, H. V. M., Yu, B., Naureckas, E. T., Nyenhuis, S. M. & Codispoti, C. D. Nov 10 2017 (Accepted/In press) In : Journal of Asthma. p. 1-8 8 p.

Research output: Research - peer-reviewArticle

Asthma
Outcome Assessment (Health Care)
Pediatrics
Phenotype
Electronic Health Records
3 Citations

Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans

Nadkarni, G. N., Galarneau, G., Ellis, S. B., Nadukuru, R., Zhang, J., Scott, S. A., Schurmann, C., Li, R., Rasmussen-Torvik, L. J., Kho, A. N., Hayes, M. G., Pacheco, J. A., Manolio, T. A., Chisholm, R. L., Roden, D. M., Denny, J. C., Kenny, E. E. & Bottinger, E. P. Mar 28 2017 In : Journal of the American College of Cardiology. 69, 12, p. 1564-1574 11 p.

Research output: Research - peer-reviewArticle

Apolipoproteins
African Americans
Blood Pressure
Alleles
Hypertension

Disease Outcomes and Care Fragmentation Among Patients With Systemic Lupus Erythematosus

Walunas, T. L., Jackson, K. L., Chung, A. H., Mancera-Cuevas, K. A., Erickson, D. L., Ramsey-Goldman, R. & Kho, A. Sep 1 2017 In : Arthritis Care and Research. 69, 9, p. 1369-1376 8 p.

Research output: Research - peer-reviewArticle

Systemic Lupus Erythematosus
Odds Ratio
Confidence Intervals
International Classification of Diseases
Infection
3 Citations

Distance from hospital impacts adverse event detection after outpatient endoscopy

Jackson, K. L., Goel, S., Kho, A. N. & Keswani, R. N. Feb 1 2017 In : Gastrointestinal Endoscopy. 85, 2, p. 380-386 7 p.

Research output: Research - peer-reviewArticle

Endoscopy
Outpatients
Mortality
Endoscopic Retrograde Cholangiopancreatography
Emergency Medical Services
5 Citations

Evolving use of seizure medications after intracerebral hemorrhage: A multicenter study

Naidech, A. M., Beaumont, J., Jahromi, B., Prabhakaran, S., Kho, A. & Holl, J. L. Jan 3 2017 In : Neurology. 88, 1, p. 52-56 5 p.

Research output: Research - peer-reviewArticle

Cerebral Hemorrhage
Multicenter Studies
Seizures
Guidelines
etiracetam
1 Citations

Genome-wide study of resistant hypertension identified from electronic health records

Dumitrescu, L. , Ritchie, M. D. , Denny, J. C. , Rouby, N. M. E. , McDonough, C. W. , Bradford, Y. , Ramirez, A. H. , Bielinski, S. J. , Basford, M. A. , Chai, H. S. , Peissig, P. , Carrell, D. , Pathak, J. , Rasmussen, L. V. , Wang, X. , Pacheco, J. A. , Kho, A. N. , Hayes, M. G. , Matsumoto, M. , Smith, M. E. & 15 others Li, R., Cooper-DeHoff, R. M., Kullo, I. J., Chute, C. G., Chisholm, R. L., Jarvik, G. P., Larson, E. B., Carey, D., McCarty, C. A., Williams, M. S., Roden, D. M., Bottinger, E., Johnson, J. A., De Andrade, M. & Crawford, D. C. Feb 1 2017 In : PLoS ONE. 12, 2, e0171745

Research output: Research - peer-reviewArticle

Genes
Health
Electronic Health Records
Genome
Hypertension
1 Citations
End Stage Liver Disease
Electronic Health Records
Fibrosis
Sodium
Transplants

The building blocks of inter-operability: A multisite analysis of patient demographic attributes available for matching

Culbertson, A. , Goel, S. , Madden, M. B. , Safaeinili, N. , Jackson, K. L. , Carton, T. , Waitman, R. , Liu, M. , Krishnamurthy, A. , Hall, L. , Cappella, N. , Visweswaran, S. , Becich, M. J. , Applegate, R. , Bernstam, E. , Rothman, R. , Matheny, M. , Lipori, G. , Bian, J. , Hogan, W. & 7 others Bell, D., Martin, A., Grannis, S., Klann, J., Sutphen, R., O’Hara, A. B. & Kho, A. Jan 1 2017 In : Applied Clinical Informatics. 8, 2, p. 322-336 15 p.

Research output: Research - peer-reviewArticle

Interoperability
Availability
Demography
Names
Electronic mail
1 Citations

Validity of cardiovascular data from electronic sources: The multi-ethnic study of atherosclerosis and HealthLNK

Ahmad, F. S., Chan, C., Rosenman, M. B., Post, W. S., Fort, D. G., Greenland, P., Liu, K. J., Kho, A. N. & Allen, N. B. Sep 1 2017 In : Circulation. 136, 13, p. 1207-1216 10 p.

Research output: Research - peer-reviewArticle

Information Storage and Retrieval
Atherosclerosis
Blood Pressure
Research
Body Mass Index
2016
2 Citations

An evaluation of recurrent diabetic ketoacidosis, fragmentation of care, and mortality across Chicago, Illinois

Mays, J. A., Jackson, K. L., Derby, T. A., Behrens, J. J., Goel, S., Molitch, M. E., Kho, A. N. & Wallia, A. Oct 1 2016 In : Diabetes Care. 39, 10, p. 1671-1676 6 p.

Research output: Research - peer-reviewArticle

Diabetic Ketoacidosis
Mortality
International Classification of Diseases
Odds Ratio
Delivery of Health Care
4 Citations

A survey of clinical phenotyping in selected national networks: demonstrating the need for high-throughput, portable, and computational methods

Richesson, R. L., Sun, J., Pathak, J., Kho, A. N. & Denny, J. C. Jul 1 2016 In : Artificial Intelligence in Medicine. 71, p. 57-61 5 p.

Research output: Research - peer-reviewArticle

Precision Medicine
Phenotype
Surveys and Questionnaires
Computational methods
Medicine
1 Citations

Communicating Chaplains’ Care: Narrative Documentation in a Neuroscience-Spine Intensive Care Unit

Johnson, R., Wirpsa, M. J., Boyken, L., Sakumoto, M., Handzo, G., Kho, A. & Emanuel, L. Oct 1 2016 In : Journal of Health Care Chaplaincy. 22, 4, p. 133-150 18 p.

Research output: Research - peer-reviewArticle

Clergy
Patient Care Team
Neurosciences
Documentation
Intensive Care Units
7 Citations

CommunityRx: A population health improvement innovation that connects clinics to communities

Lindau, S. T., Makelarski, J., Abramsohn, E., Beiser, D. G., Escamilla, V., Jerome, J., Johnson, D., Kho, A. N., Lee, K. K., Long, T. & Miller, D. C. 2016 In : Health Affairs. 35, 11, p. 2020-2029 10 p.

Research output: Research - peer-reviewArticle

Health
Population
Medical Informatics
Health Manpower
Information Services
Electronic Health Records
Ophthalmology
Visual Acuity
Research
4 Citations

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium

Verma, S. S. , Cooke Bailey, J. N. , Lucas, A. , Bradford, Y. , Linneman, J. G. , Hauser, M. A. , Pasquale, L. R. , Peissig, P. L. , Brilliant, M. H. , McCarty, C. A. , Haines, J. L. , Wiggs, J. L. , Vrabec, T. R. , Tromp, G. , Ritchie, M. D. , Bickel, J. , Chandler, A. , Holm, I. , Kohane, I. , Manzi, S. & 209 others Markianos, K., Palmer, N., Perry, C., Savova, G., Wolf, W., Wong Kong, S., Antommaria, A., Cobb, B., Harley, J., Hutton, J., Lingren, T., Lynch, J., Marsolo, K., Myers, M., Namjou, B., Prows, C., Solti, I., Vinks, S., Wagner, M., Abrams, D., Almoguera, B., Chiavacci, R., Connolly, J., Devoto, M., Hakonarson, H., Keating, B., Kim, C., Mentch, F., Qui, H., Sleiman, P., Tian, L., Vazquez, L., Bartko, B., Bock, J., Borthwick, K., Carey, D., Colonie, R., Elston, R., Faucett, A., Fetterolf, S., Gerhard, G., Kuivaniemi, H., Ledbetter, D., Lipsky, E., Pendergrass, S., Sundaresan, A., Smelser, D., Williams, J., Williams, M., Wood, C., Albrecht, J., Carlson, C., Carrell, D., Crane, P., Cronkite, D., Crosslin, D., Davis, C., Ehrlich, K., Fullterton, M., Gallego, C., Gordon, A., Grafton, J., Hansen, K., Hartzler, A., Jarvik, G., Larson, E., Leppig, K., Mukherjee, S., Ralston, J., Scrol, A., Tarczy-Hornoch, P., Trinidad, S., Bielinski, S., Bruce, K., Chute, C., De Andrade, M., Jouni, H., Heit, J., Isseh, I., Koenig, B., Kullo, I., Li, D., McCormick, J., Pathak, J., Russell, J., Schultz, C., Vitek, C., Wussow, L., Sharp, R., Olson, A., Chandra, H., Armstrong, G., Berg, R., Brautbar, A., Brilliant, M., Finamore, J., Frost, N., Hall, M., He, M., Kitchner, T., Lin, S., Linneman, J., McCarty, C., Peissig, P., Shefali, S., Strenn, R., Weichelt, B., Bagiella, E., Bottinger, E., Dieterich, D., Ellis, S., Ferryman, K., Friedman, C., Friedman, S., Galarneau, G., Gomez, A., Gottesman, O., Hulot, J. S., Horowitz, C., Hripcsak, G., Kannry, J., Kenny, E., Keppel, Y., Lin, J., Lotay, V., Mejia, A., Nadukuru, R., Peter, I., Rhodes, R., Sanderson, S., Scott, S., Ullman, T., Weijia, Z., Weng, C., Zinberg, R., Armstrong, L., Aufox, S., Baker, D., Cameron, K., Chisholm, R., Christensen, C., Greenland, P., Hayes, G., Heathcote, M., Kho, A., Lowe, B., Jackson, K., Pacheco, J., Pan, V., Persell, S., Rasmussen, L., Rasmussen-Torvik, L., Smith, M., Starren, J., Thompson, W., Wicklund, C., Brothers, K., Chen, L., Clayton, E., Cowan, J., Crawford, D., Denny, J., Edwards, T., Harris, P., Garrison, N., Malin, B., McGregor, T., Peterson, J., Roden, D., Speltz, P., Stallings, S., Stroud, M., Velez, D., Van Driest, S., Wilke, R., Basford, M., Claar, M. B., Hardebeck, A., Kirby, J., Ritchie, M., Setia, S., Kaufman, D., Li, R., Manolio, T., Allingham, R. R., Budenz, D. L., Kang, J. H., Gaasterland, D., Gaasterland, T., Lee, R. K., Lichter, P. R., Liu, Y., Moroi, S. E., Realini, A., Ritch, R., Richards, J. E., Schuman, J. S., Scott, B., Singh, K., Vollrath, D., Weinreb, R. N., Wollstein, G., Yaspan, B. L., Yoneyama, S., Zack, D., Zhang, K., Pericak-Vance, M., eMERGE Network & NEIGHBOR Consortium Sep 1 2016 In : PLoS Genetics. 12, 9, e1006186

Research output: Research - peer-reviewArticle

glaucoma
epistasis
electronics
genomics
genes

Performance of an electronic health record-based phenotype algorithm to identify community associated methicillin-resistant Staphylococcus aureus cases and controls for genetic association studies

Jackson, K. L., Mbagwu, M., Pacheco, J. A., Baldridge, A. S., Viox, D. J., Linneman, J. G., Shukla, S. K., Peissig, P. L., Borthwick, K. M., Carrell, D. A., Bielinski, S. J., Kirby, J. C., Denny, J. C., Mentch, F. D., Vazquez, L. M., Rasmussen-Torvik, L. J. & Kho, A. N. Nov 17 2016 In : BMC Infectious Diseases. 16, 1, 684

Research output: Research - peer-reviewArticle

Electronic Health Records
Genetic Association Studies
Methicillin-Resistant Staphylococcus aureus
Phenotype
Genome-Wide Association Study
1 Citations

SMCQL: Secure querying for federated databases

Bater, J., Goel, S., Elliott, G., Kho, A., Eggen, C. & Rogers, J. 2016 In : Proceedings of the VLDB Endowment. 10, 6, p. 673-684 12 p.

Research output: Research - peer-reviewArticle

Data storage equipment
Industry
10 Citations

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

Liu, C. T. , Raghavan, S. , Maruthur, N. , Kabagambe, E. K. , Hong, J. , Ng, M. C. Y. , Hivert, M. F. , Lu, Y. , An, P. , Bentley, A. R. , Drolet, A. M. , Gaulton, K. J. , Guo, X. , Armstrong, L. L. , Irvin, M. R. , Li, M. , Lipovich, L. , Rybin, D. V. , Taylor, K. D. , Agyemang, C. & 95 others Palmer, N. D., Cade, B. E., Chen, W. M., Dauriz, M., Delaney, J. A. C., Edwards, T. L., Evans, D. S., Evans, M. K., Lange, L. A., Leong, A., Liu, J., Liu, Y., Nayak, U., Patel, S. R., Porneala, B. C., Rasmussen-Torvik, L. J., Snijder, M. B., Stallings, S. C., Tanaka, T., Yanek, L. R., Zhao, W., Becker, D. M., Bielak, L. F., Biggs, M. L., Bottinger, E. P., Bowden, D. W., Chen, G., Correa, A., Couper, D. J., Crawford, D. C., Cushman, M., Eicher, J. D., Fornage, M., Franceschini, N., Fu, Y. P., Goodarzi, M. O., Gottesman, O., Hara, K., Harris, T. B., Jensen, R. A., Johnson, A. D., Jhun, M. A., Karter, A. J., Keller, M. F., Kho, A. N., Kizer, J. R., Krauss, R. M., Langefeld, C. D., Li, X., Liang, J., Liu, S., Lowe, W. L., Mosley, T. H., North, K. E., Pacheco, J. A., Peyser, P. A., Patrick, A. L., Rice, K. M., Selvin, E., Sims, M., Smith, J. A., Tajuddin, S. M., Vaidya, D., Wren, M. P., Yao, J., Zhu, X., Ziegler, J. T., Zmuda, J. M., Zonderman, A. B., Zwinderman, A. H., Adeyemo, A., Boerwinkle, E., Ferrucci, L., Hayes, M. G., Kardia, S. L. R., Miljkovic, I., Pankow, J. S., Rotimi, C. N., Sale, M. M., Wagenknecht, L. E., Arnett, D. K., Chen, Y. D. I., Nalls, M. A., Province, M. A., Kao, W. H. L., Siscovick, D. S., Psaty, B. M., Wilson, J. G., Loos, R. J. F., Dupuis, J., Rich, S. S., Florez, J. C., Rotter, J. I., Morris, A. P. & Meigs, J. B. Jul 7 2016 In : American Journal of Human Genetics. 99, 1, p. 56-75 20 p.

Research output: Research - peer-reviewArticle

Meta-Analysis
Fasting
Insulin
Glucose
Type 2 Diabetes Mellitus

Using Monte Carlo/Gaussian Based Small Area Estimates to Predict Where Medicaid Patients Reside

Behrens, J. J., Wen, X., Goel, S., Zhou, J., Fu, L. & Kho, A. N. Jan 1 2016 In : AMIA ... Annual Symposium proceedings. AMIA Symposium. 2016, p. 305-309 5 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Medicaid
Population
Health
2015
7 Citations

Building bridges across electronic health record systems through inferred phenotypic topics

Chen, Y., Ghosh, J., Bejan, C. A., Gunter, C. A., Gupta, S., Kho, A., Liebovitz, D., Sun, J., Denny, J. & Malin, B. Jan 1 2015 In : Journal of Biomedical Informatics. 55, p. 82-93 12 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Health
Population
Delivery of Health Care
Terminology
17 Citations

Desiderata for computable representations of electronic health records-driven phenotype algorithms

Mo, H. , Thompson, W. K. , Rasmussen, L. V. , Pacheco, J. A. , Jiang, G. , Kiefer, R. , Zhu, Q. , Xu, J. , Montague, E. , Carrell, D. S. , Lingren, T. , Mentch, F. D. , Ni, Y. , Wehbe, F. H. , Peissig, P. L. , Tromp, G. , Larson, E. B. , Chute, C. G. , Pathak, J. , Denny, J. C. & 10 others Speltz, P., Kho, A. N., Jarvik, G. P., Bejan, C. A., Williams, M. S., Borthwick, K., Kitchner, T. E., Roden, D. M., Harris, P. A. & Other collaborators Jan 1 2015 In : Journal of the American Medical Informatics Association. 22, 6, p. 1220-1230 11 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Phenotype
Natural Language Processing
Translational Medical Research
Terminology
15 Citations

Design and implementation of a privacy preserving electronic health record linkage tool in Chicago

Kho, A. N., Cashy, J. P., Jackson, K. L., Pah, A. R., Goel, S., Boehnke, J., Humphries, J. E., Kominers, S. D., Hota, B. N., Sims, S. A., Malin, B. A., French, D. D., Walunas, T. L., Meltzer, D. O., Kaleba, E. O., Jones, R. C. & Galanter, W. L. Jan 1 2015 In : Journal of the American Medical Informatics Association. 22, 5, p. 1072-1080 9 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Privacy
Software
Research
Health Insurance Portability and Accountability Act
12 Citations

Genetic variation in the HLA region is associated with susceptibility to herpes zoster

Crosslin, D. R. , Carrell, D. S. , Burt, A. , Kim, D. S. , Underwood, J. G. , Hanna, D. S. , Comstock, B. A. , Baldwin, E. , De Andrade, M. , Kullo, I. J. , Tromp, G. , Kuivaniemi, H. , Borthwick, K. M. , McCarty, C. A. , Peissig, P. L. , Doheny, K. F. , Pugh, E. , Kho, A. , Pacheco, J. , Hayes, M. G. & 17 others Ritchie, M. D., Verma, S. S., Armstrong, G., Stallings, S., Denny, J. C., Carroll, R. J., Crawford, D. C., Crane, P. K., Mukherjee, S., Bottinger, E., Li, R., Keating, B., Mirel, D. B., Carlson, C. S., Harley, J. B., Larson, E. B. & Jarvik, G. P. Jan 24 2015 In : Genes and Immunity. 16, 1, p. 1-7 7 p.

Research output: Research - peer-reviewArticle

Herpes Zoster
Human Herpesvirus 3
Genes
Herpes Zoster Vaccine
Endogenous Retroviruses
2014
8 Citations

Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans

Jeff, J. M., Armstrong, L. L., Ritchie, M. D., Denny, J. C., Kho, A. N., Basford, M. A., Wolf, W. A., Pacheco, J. A., Li, R., Chisholm, R. L., Roden, D. M., Geoffrey Hayes, M. & Crawford, D. C. Mar 3 2014 In : PLoS ONE. 9, 3, e86931

Research output: Research - peer-reviewArticle

Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 2
African Americans
Type 2 Diabetes Mellitus
noninsulin-dependent diabetes mellitus
48 Citations

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

Shameer, K., Denny, J. C., Ding, K., Jouni, H., Crosslin, D. R., De Andrade, M., Chute, C. G., Peissig, P., Pacheco, J. A., Li, R., Bastarache, L., Kho, A. N., Ritchie, M. D., Masys, D. R., Chisholm, R. L., Larson, E. B., McCarty, C. A., Roden, D. M., Jarvik, G. P. & Kullo, I. J. Jan 1 2014 In : Human Genetics. 133, 1, p. 95-109 15 p.

Research output: Research - peer-reviewArticle

Genome-Wide Association Study
Platelet Count
Blood Platelets
Mean Platelet Volume
Single Nucleotide Polymorphism
12 Citations

Anatomic and advanced adenoma detection rates as quality metrics determined via natural language processing

Gawron, A. J., Thompson, W. K., Keswani, R. N., Rasmussen, L. V. & Kho, A. N. Dec 11 2014 In : American Journal of Gastroenterology. 109, 12, p. 1844-1849 6 p.

Research output: Research - peer-reviewArticle

Natural Language Processing
Adenoma
Colon
Colonoscopy
Nonparametric Statistics
5 Citations

A rigorous algorithm to detect and clean inaccurate adult height records within EHR systems

Muthalagu, A., Pacheco, J. A., Aufox, S., Peissig, P. L., Fuehrer, J. T., Tromp, G., Kho, A. N. & Rasmussen-Torvik, L. J. 2014 In : Applied Clinical Informatics. 5, 1, p. 118-126 9 p.

Research output: Research - peer-reviewArticle

Body Mass Index
Research
Cleaning
Software
Aging of materials
12 Citations

CAPriCORN: Chicago area patient-centered outcomes research network

Kho, A. N. , Hynes, D. M. , Goel, S. , Solomonides, A. E. , Price, R. , Hota, B. , Sims, S. A. , Bahroos, N. , Angulo, F. , Trick, W. E. , Tarlov, E. , Rachman, F. D. , Hamilton, A. , Kaleba, E. O. , Badlani, S. , Volchenboum, S. L. , Silverstein, J. C. , Tobin, J. N. , Schwartz, M. A. , Levine, D. & 6 others Wong, J. B., Kennedy, R. H., Krishnan, J. A., Meltzer, D. O., Collins, J. M. & Mazany, T. 2014 In : Journal of the American Medical Informatics Association. 21, 4, p. 607-611 5 p.

Research output: Research - peer-reviewArticle

Patient Outcome Assessment
Health
Delivery of Health Care
Comparative Effectiveness Research
Veterans Hospitals
449 Citations

Defining the role of common variation in the genomic and biological architecture of adult human height

Wood, A. R. , Esko, T. , Yang, J. , Vedantam, S. , Pers, T. H. , Gustafsson, S. , Chu, A. Y. , Estrada, K. , Luan, J. A. , Kutalik, Z. , Amin, N. , Buchkovich, M. L. , Croteau-Chonka, D. C. , Day, F. R. , Duan, Y. , Fall, T. , Fehrmann, R. , Ferreira, T. , Jackson, A. U. , Karjalainen, J. & 425 others Lo, K. S., Locke, A. E., Mägi, R., Mihailov, E., Porcu, E., Randall, J. C., Scherag, A., Vinkhuyzen, A. A. E., Westra, H. J., Winkler, T. W., Workalemahu, T., Zhao, J. H., Absher, D., Albrecht, E., Anderson, D., Baron, J., Beekman, M., Demirkan, A., Ehret, G. B., Feenstra, B., Feitosa, M. F., Fischer, K., Fraser, R. M., Goel, A., Gong, J., Justice, A. E., Kanoni, S., Kleber, M. E., Kristiansson, K., Lim, U., Lotay, V., Lui, J. C., Mangino, M., Leach, I. M., Medina-Gomez, C., Nalls, M. A., Nyholt, D. R., Palmer, C. D., Pasko, D., Pechlivanis, S., Prokopenko, I., Ried, J. S., Ripke, S., Shungin, D., Stancáková, A., Strawbridge, R. J., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., Van Der Laan, S. W., Van Setten, J., Van Vliet-Ostaptchouk, J. V., Wang, Z., Yengo, L., Zhang, W., Afzal, U., Ärnlöv, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blüher, M., Bolton, J. L., Böttcher, Y., Boyd, H. A., Bruinenberg, M., Buckley, B. M., Buyske, S., Caspersen, I. H., Chines, P. S., Clarke, R., Claudi-Boehm, S., Cooper, M., Daw, E. W., De Jong, P. A., Deelen, J., Delgado, G., Denny, J. C., Dhonukshe-Rutten, R., Dimitriou, M., Doney, A. S. F., Dörr, M., Eklund, N., Eury, E., Folkersen, L., Garcia, M. E., Geller, F., Giedraitis, V., Go, A. S., Grallert, H., Grammer, T. B., Gräßler, J., Grönberg, H., De Groot, L. C. P. G. M., Groves, C. J., Haessler, J., Hall, P., Haller, T., Hallmans, G., Hannemann, A., Hartman, C. A., Hassinen, M., Hayward, C., Heard-Costa, N. L., Helmer, Q., Hemani, G., Henders, A. K., Hillege, H. L., Hlatky, M. A., Hoffmann, W., Hoffmann, P., Holmen, O., Houwing-Duistermaat, J. J., Illig, T., Isaacs, A., James, A. L., Jeff, J., Johansen, B., Johansson, Å., Jolley, J., Juliusdottir, T., Junttila, J., Kho, A. N., Kinnunen, L., Klopp, N., Kocher, T., Kratzer, W., Lichtner, P., Lind, L., Lindström, J., Lobbens, S., Lorentzon, M., Lu, Y., Lyssenko, V., Magnusson, P. K. E., Mahajan, A., Maillard, M., McArdle, W. L., McKenzie, C. A., McLachlan, S., McLaren, P. J., Menni, C., Merger, S., Milani, L., Moayyeri, A., Monda, K. L., Morken, M. A., Müller, G., Müller-Nurasyid, M., Musk, A. W., Narisu, N., Nauck, M., Nolte, I. M., Nöthen, M. M., Oozageer, L., Pilz, S., Rayner, N. W., Renstrom, F., Robertson, N. R., Rose, L. M., Roussel, R., Sanna, S., Scharnagl, H., Scholtens, S., Schumacher, F. R., Schunkert, H., Scott, R. A., Sehmi, J., Seufferlein, T., Shi, J., Silventoinen, K., Smit, J. H., Smith, A. V., Smolonska, J., Stanton, A. V., Stirrups, K., Stott, D. J., Stringham, H. M., Sundström, J., Swertz, M. A., Syvänen, A. C., Tayo, B. O., Thorleifsson, G., Tyrer, J. P., Van Dijk, S., Van Schoor, N. M., Van Der Velde, N., Van Heemst, D., Van Oort, F. V. A., Vermeulen, S. H., Verweij, N., Vonk, J. M., Waite, L. L., Waldenberger, M., Wennauer, R., Wilkens, L. R., Willenborg, C., Wilsgaard, T., Wojczynski, M. K., Wong, A., Wright, A. F., Zhang, Q., Arveiler, D., Bakker, S. J. L., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boomsma, D. I., Bornstein, S. R., Bovet, P., Brambilla, P., Brown, M. J., Campbell, H., Caulfield, M. J., Chakravarti, A., Collins, R., Collins, F. S., Crawford, D. C., Cupples, L. A., Danesh, J., De Faire, U., Den Ruijter, H. M., Erbel, R., Erdmann, J., Eriksson, J. G., Farrall, M., Ferrannini, E., Ferrières, J., Ford, I., Forouhi, N. G., Forrester, T., Gansevoort, R. T., Gejman, P. V., Gieger, C., Golay, A., Gottesman, O., Gudnason, V., Gyllensten, U., Haas, D. W., Hall, A. S., Harris, T. B., Hattersley, A. T., Heath, A. C., Hengstenberg, C., Hicks, A. A., Hindorff, L. A., Hingorani, A. D., Hofman, A., Hovingh, G. K., Humphries, S. E., Hunt, S. C., Hypponen, E., Jacobs, K. B., Jarvelin, M. R., Jousilahti, P., Jula, A. M., Kaprio, J., Kastelein, J. J. P., Kayser, M., Kee, F., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kooner, J. S., Kooperberg, C., Koskinen, S., Kovacs, P., Kraja, A. T., Kumari, M., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lupoli, S., Madden, P. A. F., Männistö, S., Manunta, P., Marette, A., Matise, T. C., McKnight, B., Meitinger, T., Moll, F. L., Montgomery, G. W., Morris, A. D., Morris, A. P., Murray, J. C., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Ouwehand, W. H., Pasterkamp, G., Peters, A., Pramstaller, P. P., Price, J. F., Qi, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ritchie, M., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schwarz, P. E. H., Sebert, S., Sever, P., Shuldiner, A. R., Sinisalo, J., Steinthorsdottir, V., Stolk, R. P., Tardif, J. C., Tönjes, A., Tremblay, A., Tremoli, E., Virtamo, J., Vohl, M. C., Amouyel, P., Asselbergs, F. W., Assimes, T. L., Bochud, M., Boehm, B. O., Boerwinkle, E., Bottinger, E. P., Bouchard, C., Cauchi, S., Chambers, J. C., Chanock, S. J., Cooper, R. S., De Bakker, P. I. W., Dedoussis, G., Ferrucci, L., Franks, P. W., Froguel, P., Groop, L. C., Haiman, C. A., Hamsten, A., Hayes, M. G., Hui, J., Hunter, D. J., Hveem, K., Jukema, J. W., Kaplan, R. C., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Martin, N. G., März, W., Melbye, M., Moebus, S., Munroe, P. B., Njølstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Pérusse, L., Peters, U., Powell, J. E., Power, C., Quertermous, T., Rauramaa, R., Reinmaa, E., Ridker, P. M., Rivadeneira, F., Rotter, J. I., Saaristo, T. E., Saleheen, D., Schlessinger, D., Slagboom, P. E., Snieder, H., Spector, T. D., Strauch, K., Stumvoll, M., Tuomilehto, J., Uusitupa, M., Van Der Harst, P., Völzke, H., Walker, M., Wareham, N. J., Watkins, H., Wichmann, H. E., Wilson, J. F., Zanen, P., Deloukas, P., Heid, I. M., Lindgren, C. M., Mohlke, K. L., Speliotes, E. K., Thorsteinsdottir, U., Barroso, I., Fox, C. S., North, K. E., Strachan, D. P., Beckmann, J. S., Berndt, S. I., Boehnke, M., Borecki, I. B., McCarthy, M. I., Metspalu, A., Stefansson, K., Uitterlinden, A. G., Van Duijn, C. M., Franke, L., Willer, C. J., Price, A. L., Lettre, G., Loos, R. J. F., Weedon, M. N., Ingelsson, E., O'Connell, J. R., Abecasis, G. R., Chasman, D. I., Goddard, M. E., Visscher, P. M., Hirschhorn, J. N. & Frayling, T. M. Nov 5 2014 In : Nature Genetics. 46, 11, p. 1173-1186 14 p.

Research output: Research - peer-reviewArticle

Genes
Genome
Growth
Catenins
Fibroblast Growth Factors
9 Citations

Design patterns for the development of electronic health record-driven phenotype extraction algorithms

Rasmussen, L. V., Thompson, W. K., Pacheco, J. A., Kho, A. N., Carrell, D. S., Pathak, J., Peissig, P. L., Tromp, G., Denny, J. C. & Starren, J. B. Oct 1 2014 In : Journal of Biomedical Informatics. 51, p. 280-286 7 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Phenotype
Health
Knowledge Bases
Intuition
10 Citations

Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network

Malinowski, J. R. , Denny, J. C. , Bielinski, S. J. , Basford, M. A. , Bradford, Y. , Peissig, P. L. , Carrell, D. , Crosslin, D. R. , Pathak, J. , Rasmussen, L. , Pacheco, J. , Kho, A. , Newton, K. M. , Li, R. , Kullo, I. J. , Chute, C. G. , Chisholm, R. L. , Jarvik, G. P. , Larson, E. B. , McCarty, C. A. & 5 others Masys, D. R., Roden, D. M., De Andrade, M., Ritchie, M. D. & Crawford, D. C. Dec 1 2014 In : PLoS ONE. 9, 12, e111301

Research output: Research - peer-reviewArticle

Electronic Health Records
Thyrotropin
Genomics
African Americans
Serum
54 Citations

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

Ng, M. C. Y. , Shriner, D. , Chen, B. H. , Li, J. , Chen, W. M. , Guo, X. , Liu, J. , Bielinski, S. J. , Yanek, L. R. , Nalls, M. A. , Comeau, M. E. , Rasmussen-Torvik, L. J. , Jensen, R. A. , Evans, D. S. , Sun, Y. V. , An, P. , Patel, S. R. , Lu, Y. , Long, J. , Armstrong, L. L. & 427 others Wagenknecht, L., Yang, L., Snively, B. M., Palmer, N. D., Mudgal, P., Langefeld, C. D., Keene, K. L., Freedman, B. I., Mychaleckyj, J. C., Nayak, U., Raffel, L. J., Goodarzi, M. O., Chen, Y. D. I., Taylor, H. A., Correa, A., Sims, M., Couper, D., Pankow, J. S., Boerwinkle, E., Adeyemo, A., Doumatey, A., Chen, G., Mathias, R. A., Vaidya, D., Singleton, A. B., Zonderman, A. B., Igo, R. P., Sedor, J. R., Zondervan, K. T., Kabagambe, E. K., Siscovick, D. S., McKnight, B., Rice, K., Liu, Y., Hsueh, W. C., Zhao, W., Bielak, L. F., Kraja, A., Province, M. A., Bottinger, E. P., Gottesman, O., Cai, Q., Zheng, W., Blot, W. J., Lowe, W. L., Pacheco, J. A., Crawford, D. C., Yang, T. P., Wilk, A., Grundberg, E., Tsoka, S., Rich, S. S., Hayes, M. G., Shu, X. O., Loos, R. J. F., Borecki, I. B., Peyser, P. A., Cummings, S. R., Psaty, B. M., Fornage, M., Iyengar, S. K., Evans, M. K., Becker, D. M., Kao, W. H. L., Wilson, J. G., Rotter, J. I., Sale, M. M., Liu, S., Rotimi, C. N., Bowden, D. W., Elston, R. C., Iyengar, S., Goddard, K., Olson, J., Ialacci, S., Edwards, S., Fondran, C., Horvath, A., Jun, G., Kramp, K., Slaughter, M., Zaletel, E., Sedor, J. R., Schelling, J., Sehgal, A., Pickens, A., Humbert, L., Getz-Fradley, L., Adler, S., Collins-Schramm, H. E., Ipp, E., Li1, H., Pahl, M., Seldin, M. F., LaPage, J., Walker, B., Garcia, C., Gonzalez, J., Ingram-Drake, L., Klag, M., Coresh, J., Kao, L., Mead, L., Parekh, R., Fink, N., Bayton, P., Long, Y., Wei, L., Whitehead, T., Knowler, W. C., Hanson, R. L., Nelson, R. G., Jones, L., Juan, R., Lovelace, R., Luethe, C., Phillips, L. M., Sewemaenewa, J., Sili, I., Waseta, B., Saad, M. F., Guo, X., Rotter, J., Taylor, K., Budgett, M., Zager, P., Shah, V., Scavini, M., Bobelu, A., Abboud, H., Arar, N., Duggirala, R., Kasinath, B. S., Plaetke, R., Stem, M., Goyes, C., Sartorio, V., Freedman, B. I., Bowden, D. W., Satko, S. C., Rich, S. S., Warren, S., Viverette, S., Brooks, G., Young, R., Winkler, C., Smith, M. W., Thompson, M., Hanson, R., Briggs, J. P., Kimmel, P. L., Rasooly, R., Warnock, D., Chakraborty, R., Dunston, G. M., Lifton, R. P., O’Brien, S. J., Spielman, R., McCarty, C. A., Starren, J., Peissig, P., Berg, R., Rasmussen, L., Linneman, J., Miller, A., Choudary, V., Chen, L., Waudby, C., Kitchner, T., Reeser, J., Fost, N., Ritchie, M., Wilke, R. A., Chisholm, R. L., Avila, P. C., Greenland, P., Geoffrey Hayes, M., Kho, A. N., Kibbe, W. A., Lemke, A. A., Lowe, W. L., Smith, M. E., Wolf, W. A., Pacheco, J. A., Thompson, W. K., Humowiecki, J., Law, M., Chute, C., Chute, C., Kullo, I., Koenig, B., de Andrade, M., Bielinski, S., Pathak, J., Savova, G., Wu, J., Henriksen, J., Ding, K., Hart, L., Palbicki, J., Larson, E. B., Newton, K., Ludman, E., Spangler, L., Hart, G., Carrell, D., Jarvik, G., Crane, P., Burke, W., Malia Fullerton, S., Brown Trinidad, S., Carlson, C., McDavid, A., Roden, D. M., Clayton, E., Haines, J. L., Masys, D. R., Churchill, L. R., Cornfield, D., Crawford, D., Darbar, D., Denny, J. C., Malin, B. A., Ritchie, M. D., Schildcrout, J. S., Xu, H., Havens Ramirez, A., Basford, M., Pulley, J., Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., Mcculloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., Mccarroll, S. A., Langenberg, C., Hofmann, O. M., Dupuis, J., Qi, L., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bengtsson Boström, K., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Perry, J. R. B., Petersen, A. K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H. M., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R. M., van Haeften, T. W., van Herpt, T., van Vliet-Ostaptchouk, J. V., Walters, G. B., Weedon, M. N., Wijmenga, C., Witteman, J., Tsaprouni, L., Travers, M. E., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Florez, J. C., Frayling, T. M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., van duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M., Mccarthy, M. I., Ahmadi, K. R., Ainali, C., Barrett, A., Bataille, V., Bell, J. T., Buil, A., Deloukas, P., Dermitzakis, E. T., Dimas, A. S., Durbin, R., Glass, D., Grundberg, E., Hassanali, N., Hedman, Å. K., Ingle, C., Knowles, D., Krestyaninova, M., Lindgren, C. M., Lowe, C. E., McCarthy, M. I., Meduri, E., di Meglio, P., Min, J. L., Montgomery, S. B., Nestle, F. O., Nica, A. C., Nisbet, J., O’Rahilly, S., Parts, L., Potter, S., Sekowska, M., Shin, S. Y., Small, K. S., Soranzo, N., Spector, T. D., Surdulescu, G., The MAGIC investigators & The GIANT consortium Aug 7 2014 In : PLoS Genetics. 10, 8, e1004517

Research output: Research - peer-reviewArticle

African Americans
noninsulin-dependent diabetes mellitus
meta-analysis
loci
genome-wide association study
3 Citations

Nascent regional system for alerting infection preventionists about patients with multidrug-resistant gram-negative bacteria: Implementation and initial results

Rosenman, M. B., Szucs, K. A., Finnell, S. M. E., Khokhar, S., Egg, J., Lemmon, L., Shepherd, D. C., Friedlin, J., Li, X. & Kho, A. N. Oct 1 2014 In : Infection Control and Hospital Epidemiology. 35, p. S40-S47

Research output: Research - peer-reviewArticle

Gram-Negative Bacteria
Infection
Microbiology
Enterobacteriaceae
Hospital Emergency Service
3 Citations

Silence in the EHR: Infrequent documentation of aphonia in the electronic health record

Morris, M. A. & Kho, A. N. Sep 23 2014 In : BMC Health Services Research. 14, 1, 425

Research output: Research - peer-reviewArticle

Aphonia
Electronic Health Records
Documentation
Communication
Communication Disorders

Use of herbal supplements with undeclared drug ingredients masking giant cell arteritis

Mbagwu, M. C., Weisman, P. S. & Kho, A. N. 2014 In : Journal of Clinical Rheumatology. 20, 1, p. 51-53 3 p.

Research output: Research - peer-reviewArticle

Plant Preparations
Phytotherapy
Temporal Arteries
Giant Cell Arteritis
Delayed Diagnosis
2013
11 Citations

A regional informatics platform for coordinated antibiotic-resistant infection tracking, alerting, and prevention

Kho, A. N., Doebbeling, B. N., Cashy, J. P., Rosenman, M. B., Dexter, P. R., Shepherd, D. C., Lemmon, L., Teal, E., Khokar, S. & Overhage, J. M. Jul 15 2013 In : Clinical Infectious Diseases. 57, 2, p. 254-262 9 p.

Research output: Research - peer-reviewArticle

Informatics
Anti-Bacterial Agents
Infection
Registries
Delivery of Health Care
19 Citations

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans

Jeff, J. M., Ritchie, M. D., Denny, J. C., Kho, A. N., Ramirez, A. H., Crosslin, D., Armstrong, L., Basford, M. A., Wolf, W. A., Pacheco, J. A., Chisholm, R. L., Roden, D. M., Hayes, M. G. & Crawford, D. C. 2013 In : Annals of Human Genetics. 77, 4, p. 321-332 12 p.

Research output: Research - peer-reviewArticle

Genome-Wide Association Study
African Americans
Population
Heart Rate
Direction compound
15 Citations

Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: An electronic medical record-based genome-wide association study

Ding, K., Andrade, M. D., Manolio, T. A., Crawford, D. C., Rasmussen-Torvik, L. J., Ritchie, M. D., Denny, J. C., Masys, D. R., Jouni, H., Pachecho, J. A., Kho, A. N., Roden, D. M., Chisholm, R. & Kullo, I. J. Jan 1 2013 In : G3: Genes, Genomes, Genetics. 3, 7, p. 1061-1068 8 p.

Research output: Research - peer-reviewArticle

Erythrocyte Indices
Electronic Health Records
Genome-Wide Association Study
African Americans
Malaria
29 Citations

Genetic variation associated with circulating monocyte count in the eMERGE Network

Crosslin, D. R. , McDavid, A. , Weston, N. , Zheng, X. , Hart, E. , de Andrade, M. , Kullo, I. J. , McCarty, C. A. , Doheny, K. F. , Pugh, E. , Kho, A. , Hayes, M. G. , Ritchie, M. D. , Saip, A. , Crawford, D. C. , Crane, P. K. , Newton, K. , Carrell, D. S. , Gallego, C. J. , Nalls, M. A. & 44 others Li, R., Mirel, D. B., Crenshaw, A., Couper, D. J., Tanaka, T., van Rooij, F. J. A., Chen, M. H., Smith, A. V., Zakai, N. A., Yango, Q., Garcia, M., Liu, Y., Lumley, T., Folsom, A. R., Reiner, A. P., Felix, J. F., Dehghan, A., Wilson, J. G., Bis, J. C., Fox, C. S., Glazer, N. L., Cupples, L. A., Coresh, J., Eiriksdottir, G., Gudnason, V., Bandinelli, S., Frayling, T. M., Chakravarti, A., van Duijn, C. M., Melzer, D., Levy, D., Boerwinkle, E., Singleton, A. B., Hernandez, D. G., Longo, D. L., Witteman, J. C. M., Psaty, B. M., Ferrucci, L., Harris, T. B., O'Donnell, C. J., Ganesh, S. K., Larson, E. B., Carlson, C. S. & Jarvik, G. P. May 1 2013 In : Human Molecular Genetics. 22, 10, p. 2119-2127 9 p.

Research output: Research - peer-reviewArticle

Monocytes
Genes
Joints
interferon regulatory factor-8
Lysophosphatidic Acid Receptors
83 Citations

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk

Ritchie, M. D. , Denny, J. C. , Zuvich, R. L. , Crawford, D. C. , Schildcrout, J. S. , Bastarache, L. , Ramirez, A. H. , Mosley, J. D. , Pulley, J. M. , Basford, M. A. , Bradford, Y. , Rasmussen, L. V. , Pathak, J. , Chute, C. G. , Kullo, I. J. , Mccarty, C. A. , Chisholm, R. L. , Kho, A. N. , Carlson, C. S. , Larson, E. B. & 7 others Jarvik, G. P., Sotoodehnia, N., Manolio, T. A., Li, R., Masys, D. R., Haines, J. L. & Roden, D. M. Apr 2 2013 In : Circulation. 127, 13, p. 1377-1385 9 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Cardiac Arrhythmias
Genome
Genomics
Epidemiology
6 Citations

Migration of patients between five urban teaching hospitals in Chicago

Galanter, W. L., Applebaum, A., Boddipalli, V., Kho, A., Lin, M., Meltzer, D., Roberts, A., Trick, B., Walton, S. M. & Lambert, B. L. Apr 1 2013 In : Journal of Medical Systems. 37, 2, 9930

Research output: Research - peer-reviewArticle

Urban Hospitals
Teaching Hospitals
Teaching
Mothers
Patient Discharge
2 Citations

Multihospital infection prevention collaborative: informatics challenges and strategies to prevent MRSA.

Doebbeling, B. N., Flanagan, M. E., Nall, G., Hoke, S., Rosenman, M. & Kho, A. 2013 In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2013, p. 317-325 9 p.

Research output: Research - peer-reviewArticle

Informatics
Methicillin-Resistant Staphylococcus aureus
Infection
Information Storage and Retrieval
Ontario
170 Citations

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

Denny, J. C. , Bastarache, L. , Ritchie, M. D. , Carroll, R. J. , Zink, R. , Mosley, J. D. , Field, J. R. , Pulley, J. M. , Ramirez, A. H. , Bowton, E. , Basford, M. A. , Carrell, D. S. , Peissig, P. L. , Kho, A. N. , Pacheco, J. A. , Rasmussen, L. V. , Crosslin, D. R. , Crane, P. K. , Pathak, J. , Bielinski, S. J. & 16 others Pendergrass, S. A., Xu, H., Hindorff, L. A., Li, R., Manolio, T. A., Chute, C. G., Chisholm, R. L., Larson, E. B., Jarvik, G. P., Brilliant, M. H., Mccarty, C. A., Kullo, I. J., Haines, J. L., Crawford, D. C., Masys, D. R. & Roden, D. M. Dec 1 2013 In : Nature Biotechnology. 31, 12, p. 1102-1110 9 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Genome-Wide Association Study
Phenotype
Electronic medical equipment
Genes
17 Citations

The absence of longitudinal data limits the accuracy of high-throughput clinical phenotyping for identifying type 2 diabetes mellitus subjects

Wei, W. Q., Leibson, C. L., Ransom, J. E., Kho, A. N. & Chute, C. G. Apr 1 2013 In : International Journal of Medical Informatics. 82, 4, p. 239-247 9 p.

Research output: Research - peer-reviewArticle

Type 2 Diabetes Mellitus
Electronic Health Records
Clinical Laboratory Techniques
Gold
Retrospective Studies
110 Citations

Validation of electronic medical record-based phenotyping algorithms: Results and lessons learned from the eMERGE network

Newton, K. M., Peissig, P. L., Kho, A. N., Bielinski, S. J., Berg, R. L., Choudhary, V., Basford, M., Chute, C. G., Kullo, I. J., Li, R., Pacheco, J. A., Rasmussen, L. V., Spangler, L. & Denny, J. C. Aug 28 2013 In : Journal of the American Medical Informatics Association. 20, E1

Research output: Research - peer-reviewArticle

Electronic Health Records
Genomics
Phenotype
Health
Biomedical Research
2012
17 Citations

An evaluation of the NQF Quality Data Model for representing Electronic Health Record driven phenotyping algorithms.

Thompson, W. K., Rasmussen, L. V., Pacheco, J. A., Peissig, P. L., Denny, J. C., Kho, A. N., Miller, A. & Pathak, J. 2012 In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2012, p. 911-920 10 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Data Accuracy
Aptitude
Language
Phenotype
3 Citations

Concept and development of a discharge alert filter for abnormal laboratory values coupled with computerized provider order entry: A tool for quality improvement and hospital risk management

Mathew, G., Kho, A., Dexter, P., Bloodworth, N., Fantz, C., Spell, N. & Laborde, D. V. Jun 2012 In : Journal of Patient Safety. 8, 2, p. 69-75 7 p.

Research output: Research - peer-reviewArticle

Medical Order Entry Systems
Risk Management
Quality Improvement
Patient Safety
Reference Values
21 Citations

Genetic loci implicated in erythroid differentiation and cell cycle regulation are associated with red blood cell traits

Ding, K., Shameer, K., Jouni, H., Masys, D. R., Jarvik, G. P., Kho, A. N., Ritchie, M. D., McCarty, C. A., Chute, C. G., Manolio, T. A. & Kullo, I. J. 2012 In : Mayo Clinic Proceedings. 87, 5, p. 461-474 14 p.

Research output: Research - peer-reviewArticle

Erythroid Cells
Genetic Loci
Cell Cycle
Erythrocytes
Erythrocyte Indices
55 Citations

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network

Crosslin, D. R. , McDavid, A. , Weston, N. , Nelson, S. C. , Zheng, X. , Hart, E. , De Andrade, M. , Kullo, I. J. , McCarty, C. A. , Doheny, K. F. , Pugh, E. , Kho, A. , Hayes, M. G. , Pretel, S. , Saip, A. , Ritchie, M. D. , Crawford, D. C. , Crane, P. K. , Newton, K. , Li, R. & 5 others Mirel, D. B., Crenshaw, A., Larson, E. B., Carlson, C. S. & Jarvik, G. P. Apr 2012 In : Human Genetics. 131, 4, p. 639-652 14 p.

Research output: Research - peer-reviewArticle

Electronic Health Records
Genomics
Leukocyte Count
Phenotype
Antigens