• 32883 Citations
1984 …2027
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Research Output 1984 2019

2003
80 Citations (Scopus)

The correlation between patient characteristics and expectations of benefit from phase I clinical trials

Weinfurt, K. P., Castel, L. D., Li, Y., Sulmasy, D. P., Balshem, A. M., Benson III, A. B., Burnett, C. B., Gaskin, D. J., Marshall, J. L., Slater, E. F., Schulman, K. A. & Meropol, N. J., Jul 1 2003, In : Cancer. 98, 1, p. 166-175 10 p.

Research output: Contribution to journalArticle

Clinical Trials, Phase I
Investigational Therapies
Quality of Life
Informed Consent
Personality
74 Citations (Scopus)

Thymidylate synthase protein expression in primary colorectal cancer: Lack of correlation with outcome and response to fluorouracil in metastatic disease sites

Johnston, P. G., Benson, A. B., Catalano, P., Rao, M. S., O'Dwyer, P. J. & Allegro, C. J., Mar 1 2003, In : Journal of Clinical Oncology. 21, 5, p. 815-819 5 p.

Research output: Contribution to journalArticle

Thymidylate Synthase
Fluorouracil
Colorectal Neoplasms
Proteins
Leucovorin

Treatment of gastric cancer for survival-strategies in the USA and Japan

Baddi, L., Mulcahy, M. F. & Benson III, A. B., Jan 1 2003, In : Annals of Cancer Research and Therapy. 11, 1-2, p. 15-30 16 p.

Research output: Contribution to journalArticle

docetaxel
Stomach Neoplasms
Japan
Survival
Genetic Polymorphisms
6 Citations (Scopus)

ZD9331 in combination with topotecan: Phase I and II experience

Benson III, A. B., Poplin, E. & Vergote, I., Jan 1 2003, In : Anti-Cancer Drugs. 14, SUPPL. 1

Research output: Contribution to journalArticle

Topotecan
ZD 9331
Ovarian Neoplasms
Neoplasms
Topoisomerase Inhibitors
2002
257 Citations (Scopus)

Adjuvant therapy in rectal cancer: Analysis of stage, sex, and local control - Final report of Intergroup 0114

Tepper, J. E., O'Connell, M., Niedzwiecki, D., Hollis, D. R., Benson, A. B., Cummings, B., Gunderson, L. L., Macdonald, J. S., Martenson, J. A. & Mayer, R. J., Apr 1 2002, In : Journal of Clinical Oncology. 20, 7, p. 1744-1750 7 p.

Research output: Contribution to journalArticle

Rectal Neoplasms
Fluorouracil
Levamisole
Leucovorin
Drug Therapy
352 Citations (Scopus)

Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: Surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy - An intergroup study

Kemeny, M. M., Adak, S., Gray, B., Macdonald, J. S., Smith, T., Lipsitz, S., Sigurdson, E. R., O'Dwyer, P. J. & Benson, A. B., Mar 15 2002, In : Journal of Clinical Oncology. 20, 6, p. 1499-1505 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Neoplasm Metastasis
Drug Therapy
Liver
Recurrence
13 Citations (Scopus)

Eastern cooperative oncology group phase II trial (E4296) of oral 5-fluorouracil and eniluracil as a 28-day regimen in metastatic colorectal cancer

Marsh, J. C., Catalano, P., Huang, J., Graham, D. L., Cornfeld, M. J., O'Dwyer, P. J. & Benson III, A. B., Jan 1 2002, In : Clinical colorectal cancer. 2, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Fluorouracil
Colorectal Neoplasms
eniluracil
Phase II Clinical Trials
Stomatitis
67 Citations (Scopus)

Epidermal growth factor receptor-targeted therapy in colorectal cancer

O'Dwyer, P. J. & Benson III, A. B., Jan 1 2002, In : Seminars in Oncology. 29, 5, p. 10-17 8 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Colorectal Neoplasms
Therapeutics
Immunotoxins
Growth Inhibitors
4 Citations (Scopus)

Future directions in adjuvant therapy for rectal cancer.

Benson III, A. B., May 1 2002, In : Oncology (Williston Park, N.Y.). 16, 5 Suppl 5, p. 45-51 7 p.

Research output: Contribution to journalReview article

Rectal Neoplasms
Fluorouracil
oxaliplatin
irinotecan
Lymph Nodes
25 Citations (Scopus)
Colorectal Neoplasms
Therapeutics
Colonoscopy
Neoplasms
Biomarkers
15 Citations (Scopus)

Oral eniluracil/5-fluorouracil in patients with inoperable hepatocellular carcinoma

Benson III, A. B., Mitchell, E., Abramson, N., Klencke, B., Ritch, P., Burnham, J. P., McGuirt, C., Bonny, T., Levin, J. & Hohneker, J., Jan 1 2002, In : Annals of Oncology. 13, 4, p. 576-581 6 p.

Research output: Contribution to journalArticle

Fluorouracil
Hepatocellular Carcinoma
Dihydrouracil Dehydrogenase (NADP)
Confidence Intervals
eniluracil
108 Citations (Scopus)

Outcomes and toxicity in African-American and Caucasians patients in a randomized adjuvant chemotherapy trial for colon cancer

McCollum, A. D., Catalano, P. J., Haller, D. G., Mayer, R. J., Macdonald, J. S., Benson III, A. B. & Fuchs, C. S., Aug 7 2002, In : Journal of the National Cancer Institute. 94, 15, p. 1160-1167 8 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
African Americans
Colonic Neoplasms
Confidence Intervals
Disease-Free Survival
643 Citations (Scopus)

Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group trial E2297

Berlin, J. D., Catalano, P., Thomas, J. P., Kugler, J. W., Haller, D. G. & Benson, A. B., Aug 1 2002, In : Journal of Clinical Oncology. 20, 15, p. 3270-3275 6 p.

Research output: Contribution to journalArticle

gemcitabine
Fluorouracil
Pancreatic Carcinoma
Survival
11 Citations (Scopus)

Pilot study of gemcitabine (10 mg/m2 per min) and cisplatin

Poplin, E., Benson, A., Musanti, R., Rubin, E. & Mulcahy, M., Jul 18 2002, In : Cancer Chemotherapy and Pharmacology. 50, 1, p. 80-83 4 p.

Research output: Contribution to journalArticle

gemcitabine
Cisplatin
Agranulocytosis
Patient treatment
18 Citations (Scopus)
docetaxel
Hydroxyurea
Fluorouracil
Doxorubicin
Interferons
6 Citations (Scopus)

Recent and ongoing clinical trials for treating colorectal cancer

Mulcahy, M. F. & Benson III, A. B., Jun 22 2002, In : Expert Opinion on Investigational Drugs. 11, 6, p. 871-880 10 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Clinical Trials
irinotecan
Fluorouracil
Colonic Neoplasms
2001
783 Citations (Scopus)

Adjuvant radiotherapy for rectal cancer: A systematic overview of 8507 patients from 22 randomised trials

Colorectal Cancer Collaborative Group, Jan 1 2001, In : Lancet. 358, 9290, p. 1291-1304 14 p.

Research output: Contribution to journalArticle

Adjuvant Radiotherapy
Rectal Neoplasms
Radiotherapy
Recurrence
Appointments and Schedules
54 Citations (Scopus)

A phase II study of irinotecan with 5-fluorouracil and leucovorin in patients with previously untreated gastric adenocarcinoma

Blanke, C. D., Haller, D. G., Benson III, A. B., Rothenberg, M. L., Berlin, J., Mori, M., Hsieh, Y. C. & Miller, L. L., Dec 1 2001, In : Annals of Oncology. 12, 11, p. 1575-1580 6 p.

Research output: Contribution to journalArticle

irinotecan
Leucovorin
Fluorouracil
Stomach
Adenocarcinoma

Chemoprevention of colon cancer.

Mulcahy, M. F. & Benson III, A. B., Jan 1 2001, In : Cancer Treatment and Research. 106, p. 155-182 28 p.

Research output: Contribution to journalReview article

Anticarcinogenic Agents
Hematinics
Dietary Fats
Chemoprevention
Dietary Fiber

Erratum: Irinotecan-induced dysarthria (Journal of the National Cancer Institute (2001) vol. 93 (18) (1420))

Della Rovere, Q. & Benson, A., Nov 7 2001, In : Journal of the National Cancer Institute. 93, 21, 1 p.

Research output: Contribution to journalComment/debate

irinotecan
Dysarthria
National Cancer Institute (U.S.)
33 Citations (Scopus)

Familial pulmonary carcinoid tumors

Oliveira, A. M., Tazelaar, H. D., Wentzlaff, K. A., Kosugi, N. S., Hai, N., Benson III, A. B., Miller, D. L. & Yang, P., Jun 1 2001, In : Cancer. 91, 11, p. 2104-2109 6 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia Type 1
Carcinoid Tumor
Lung
Germ-Line Mutation
Nuclear Family
70 Citations (Scopus)

Fluorouracil modulation in colorectal cancer: Lack of improvement with N-phosphonoacetyl-l-aspartic acid or oral leucovorin or interferon, but enhanced therapeutic index with weekly 24-hour infusion schedule an Eastern Cooperative Oncology Group/Cancer and leukemia group B study

O'Dwyer, P. J., Manola, J., Valone, F. H., Ryan, L. M., Hines, J. D., Wadler, S., Haller, D. G., Arbuck, S. G., Weiner, L. M., Mayer, R. J. & Benson, A. B., May 1 2001, In : Journal of Clinical Oncology. 19, 9, p. 2413-2421 9 p.

Research output: Contribution to journalArticle

Leucovorin
Aspartic Acid
Fluorouracil
Interferons
Colorectal Neoplasms
460 Citations (Scopus)

Impact of number of nodes retrieved on outcome in patients with rectal cancer

Tepper, J. E., O'Connell, M. J., Niedzwiecki, D., Hollis, D., Compton, C., Benson, A. B., Cummings, B., Gunderson, L., Macdonald, J. S. & Mayer, R. J., Jan 1 2001, In : Journal of Clinical Oncology. 19, 1, p. 157-163 7 p.

Research output: Contribution to journalArticle

Rectal Neoplasms
Lymph Nodes
Recurrence
Survival
Radiotherapy
181 Citations (Scopus)

Indications and results of liver resection and hepatic chemoembolization for metastatic gastrointestinal neuroendocrine tumors

Yao, K. A., Talamonti, M. S., Nemcek Jr, A. A., Angelos, P., Chrisman, H. B., Skarda, J., Benson III, A. B., Musunuri, S. R. & Joehl, R. J., Jan 1 2001, In : Surgery. 130, 4, p. 677-685 9 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Liver
Neoplasm Metastasis
Survival
Neoplasms
735 Citations (Scopus)

Molecular predictors of survival after adjuvant chemotherapy for colon cancer

Watanabe, T., Wu, T. T., Catalano, P. J., Ueki, T., Satriano, R., Haller, D. G., Benson III, A. B. & Hamilton, S. R., Apr 19 2001, In : New England Journal of Medicine. 344, 16, p. 1196-1206 11 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Colonic Neoplasms
Survival
Microsatellite Instability
Neoplasms
2 Citations (Scopus)

Oral eniluracil/5-FU for advanced colon and breast carcinomas

Benson III, A. B., Dec 1 2001, In : Oncology. 15, 1 SUPPL. 2, p. 57-63 7 p.

Research output: Contribution to journalArticle

Fluorouracil
Colon
Dihydrouracil Dehydrogenase (NADP)
Breast Neoplasms
Appointments and Schedules
2000
125 Citations (Scopus)

2000 Update of American Society of Clinical Oncology colorectal cancer surveillance guidelines

Benson, A. B., Desch, C. E., Flynn, P. J., Krause, C., Loprinzi, C. L., Minsky, B. D., Petrelli, N. J., Pfister, D. G., Smith, T. J. & Somerfield, M. R., Oct 15 2000, In : Journal of Clinical Oncology. 18, 20, p. 3586-3588 3 p.

Research output: Contribution to journalArticle

Local Neoplasm Recurrences
Sigmoidoscopy
Occult Blood
X Ray Computed Tomography
Medical Oncology
192 Citations (Scopus)

Adjuvant active specific immunotherapy for stage II and III colon cancer with an autologous tumor cell vaccine: Eastern Cooperative Oncology Group study E5283

Harris, J. E., Ryan, L., Hoover, H. C., Stuart, R. K., Oken, M. M., Benson, A. B., Mansour, E., Haller, D. G., Manola, J. & Hanna, M. G., Jan 1 2000, In : Journal of Clinical Oncology. 18, 1, p. 148-157 10 p.

Research output: Contribution to journalArticle

Active Immunotherapy
Cancer Vaccines
Colonic Neoplasms
Disease-Free Survival
Delayed Hypersensitivity
68 Citations (Scopus)

A phase II study of gemcitabine and 5-fluorouracil in metastatic pancreatic cancer: An Eastern Cooperative Oncology Group study (E3296)

Berlin, J. D., Adak, S., Vaughn, D. J., Flinker, D., Blaszkowsky, L., Harris, J. E. & Benson III, A. B., Jan 1 2000, In : Oncology. 58, 3, p. 215-218 4 p.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Fluorouracil
Informed Consent
Survival Rate
17 Citations (Scopus)

A pilot trial of suramin in metastatic breast cancer to assess antiangiogenic activity in individual patients

Gradishar, W. J., Soff, G., Liu, J., Cisneros, A., French, S., Rademaker, A. W., Benson III, A. B. & Bouck, N., Jan 1 2000, In : ONCOLOGY. 58, 4, p. 324-333 10 p.

Research output: Contribution to journalArticle

Suramin
Breast Neoplasms
Neoplasms
Cell Migration Assays
Angiogenesis Inhibitors
13 Citations (Scopus)

Chronic daily low dose of 4-methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione (oltipraz) in patients with previously resected colon polyps and first-degree female relatives of breast cancer patients

Benson III, A. B., Olopade, O. I., Ratain, M. J., Rademaker, A. W., Mobarhan, S., Stucky-Marshall, L., French, S. & Dolan, M. E., Jan 1 2000, In : Clinical Cancer Research. 6, 10, p. 3870-3877 8 p.

Research output: Contribution to journalArticle

Polyps
Colon
Breast Neoplasms
Glutathione Transferase
Lymphocytes
113 Citations (Scopus)

Eastern Cooperative Oncology Group, phase I trial of protracted venous infusion fluorouracil plus weekly gemcitabine with concurrent radiation therapy in patients with locally advanced pancreas cancer: A regimen with unexpected early toxicity

Talamonti, M. S., Catalano, P. J., Vaughn, D. J., Whittington, R., Beauchamp, R. D., Berlin, J. & Benson III, A. B., Oct 1 2000, In : Journal of Clinical Oncology. 18, 19, p. 3384-3389 6 p.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Fluorouracil
Radiotherapy
Radiation
65 Citations (Scopus)

Management of cancer treatment-related diarrhea: Issues and therapeutic strategies

Kornblau, S., Benson III, A. B., Catalano, R., Champlin, R. E., Engelking, C., Field, M., Ippoliti, C., Lazarus, H. M., Mitchell, E., Rubin, J., Stiff, P. J., Vokes, E. & Wadler, S., Jan 1 2000, In : Journal of Pain and Symptom Management. 19, 2, p. 118-129 12 p.

Research output: Contribution to journalArticle

Second Primary Neoplasms
Diarrhea
Graft vs Host Disease
irinotecan
Therapeutics
46 Citations (Scopus)

NCCN Practice Guidelines for Colorectal Cancer.

Benson III, A. B., Choti, M. A., Cohen, A. M., Doroshow, J. H., Fuchs, C., Kiel, K., Martin, E. W., McGinn, C., Petrelli, N. J., Posey, J. A., Skibber, J. M., Venook, A. & Yeatman, T. J., Jan 1 2000, In : Oncology (Williston Park, N.Y.). 14, 11 A, p. 203-212 10 p.

Research output: Contribution to journalArticle

Practice Guidelines
Colorectal Neoplasms
irinotecan
Fluorouracil
Clinical Trials
4 Citations (Scopus)
Menogaril
B-Cell Chronic Lymphocytic Leukemia
Multiple Myeloma
Drug Therapy
Anthracyclines
8 Citations (Scopus)

Treatment of squamous cell esophageal cancer with topotecan: An Eastern Cooperative Oncology Group Study (E2293)

Asbury, R. F., Lipsitz, S., Graham, D., Falkson, C. I., Baez, L. & Benson, A. B., Feb 1 2000, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 23, 1, p. 45-46 2 p.

Research output: Contribution to journalArticle

Topotecan
Squamous Cell Neoplasms
Esophageal Neoplasms
Esophagus
Squamous Cell Carcinoma
1999
7 Citations (Scopus)

A phase II study of 5-fluorouracil, leucovorin, and interferon-α in the treatment of patients with metastatic or recurrent gastric carcinoma: An Eastern Cooperative Oncology Group study (E5292)

Hudes, G. R., Lipsitz, S., Grem, J., Morrisey, M., Weiner, L., Kugler, J. W. & Benson, A., Feb 2 1999, In : Cancer. 85, 2, p. 290-294 5 p.

Research output: Contribution to journalArticle

Leucovorin
Fluorouracil
Interferons
Stomach
Carcinoma
125 Citations (Scopus)

Final report of intergroup trial 0122 (ECOG PE-289, RTOG 90-12): Phase II trial of neoadjuvant chemotherapy plus concurrent chemotherapy and high- dose radiation for squamous cell carcinoma of the esophagus

Minsky, B. D., Neuberg, D., Kelsen, D. P., Pisansky, T. M., Ginsberg, R. J., Pajak, T., Salter, M. & Benson III, A. B., Feb 1 1999, In : International Journal of Radiation Oncology Biology Physics. 43, 3, p. 517-523 7 p.

Research output: Contribution to journalArticle

esophagus
chemotherapy
Esophagus
Squamous Cell Carcinoma
cancer

NCCN practice guidelines for hepatobiliary cancers

Benson III, A. B., Dec 1 1999, In : ONCOLOGY. 13, 11 A, p. 265-291 27 p.

Research output: Contribution to journalArticle

Practice Guidelines
Neoplasms
192 Citations (Scopus)

Recommended colorectal cancer surveillance guidelines the American Society of Clinical Oncology

Desch, C. E., Benson, A. B., Smith, T. J., Flynn, P. J., Krause, C., Loprinzi, C. L., Minsky, B. D., Petrelli, N. J., Pfister, D. G., Somerfield, M. R. & Padberg, J. J., Jan 1 1999, In : Journal of Clinical Oncology. 17, 4, p. 1312-1321 10 p.

Research output: Contribution to journalArticle

Medical Oncology
Colorectal Neoplasms
Guidelines
Cost-Benefit Analysis
Costs and Cost Analysis
226 Citations (Scopus)

Sphincter-sparing treatment for distal rectal adenocarcinoma

Steele, G. D., Herndon, J. E., Bleday, R., Russell, A., Benson, A., Hussain, M., Burgess, A., Tepper, J. E. & Mayer, R. J., Jul 1 1999, In : Annals of Surgical Oncology. 6, 5, p. 433-441 9 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Therapeutics
Anal Canal
Recurrence
Rectal Neoplasms
5 Citations (Scopus)

The role of carcinoembryonic antigen monitoring in management of colorectal cancer.

Mulcahy, M. F. & Benson III, A. B., Jan 1 1999, In : Current Oncology Reports. 1, 2, p. 168-172 5 p.

Research output: Contribution to journalReview article

Carcinoembryonic Antigen
Colorectal Neoplasms
Physiologic Monitoring
Neoplasm Metastasis
Antigens
1998
63 Citations (Scopus)

High dose chemoradiotherapy followed by esophagectomy for adenocarcinoma of the esophagus and gastroesophageal junction: Results of a phase II study of the eastern cooperative oncology group

Keller, S. M., Ryan, L. M., Coia, L. R., Dang, P., Vaught, D. J., Diggs, C., Weiner, L. M. & Benson III, A. B., Nov 1 1998, In : Cancer. 83, 9, p. 1908-1916 9 p.

Research output: Contribution to journalArticle

Esophagogastric Junction
Esophagectomy
Chemoradiotherapy
Survival
Fluorouracil
5 Citations (Scopus)

Local-regional therapy for metastatic liver tumors.

Talamonti, M. S., Tellez, C. & Benson III, A. B., Jan 1 1998, In : Cancer Treatment and Research. 98, p. 172-199 28 p.

Research output: Contribution to journalReview article

Therapeutic Chemoembolization
Intra Arterial Infusions
Combined Modality Therapy
Phase II Clinical Trials
Cryosurgery
154 Citations (Scopus)

Phase II trial of chemoembolization for the treatment of metastatic colorectal carcinoma to the liver and review of the literature

Tellez, C., Benson, A. B., Lyster, M. T., Talamonti, M., Shaw, J., Braun, M. A., Nemcek, A. A. & Vogelzang, R. L., Apr 1 1998, In : Cancer. 82, 7, p. 1250-1259 10 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Liver
Hepatic Artery
Neoplasm Metastasis
Therapeutics
312 Citations (Scopus)

Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: An Eastern Cooperative Oncology Group Study

Hoffman, J. P., Lipsitz, S., Pisansky, T., Weese, J. L., Solin, L. & Benson, A. B., Jan 1 1998, In : Journal of Clinical Oncology. 16, 1, p. 317-323 7 p.

Research output: Contribution to journalArticle

Pancreas
Adenocarcinoma
Radiotherapy
Drug Therapy
Pancreatectomy
121 Citations (Scopus)

Recommended guidelines for the treatment of chemotherapy-induced diarrhea

Wadler, S., Benson, A. B., Engelking, C., Catalano, R., Field, M., Kornblau, S. M., Mitchell, E., Rubin, J., Trotta, P. & Vokes, E., Jan 1 1998, In : Journal of Clinical Oncology. 16, 9, p. 3169-3178 10 p.

Research output: Contribution to journalReview article

Diarrhea
Guidelines
Drug Therapy
Therapeutics
Octreotide
16 Citations (Scopus)

Regional and systemic therapies for advanced colorectal carcinoma: Randomized clinical trial results

Benson III, A. B., Dec 5 1998, In : Oncology. 12, 10 SUPPL. 7, p. 28-34 7 p.

Research output: Contribution to journalArticle

Fluorouracil
Colorectal Neoplasms
Randomized Controlled Trials
Leucovorin
Therapeutics
48 Citations (Scopus)

Therapy for advanced colorectal cancer

Benson III, A. B., Oct 29 1998, In : Seminars in Oncology. 25, 5 SUPPL., p. 2-11 10 p.

Research output: Contribution to journalReview article

Fluorouracil
Colorectal Neoplasms
oxaliplatin
irinotecan
Liver
1997
241 Citations (Scopus)

Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: Initial results of intergroup 0114

Tepper, J. E., O'Connell, M. J., Petroni, G. R., Hollis, D., Cooke, E., Benson, A. B., Cummings, B., Gunderson, L. L., Macdonald, J. S. & Martenson, J. A., Jan 1 1997, In : Journal of Clinical Oncology. 15, 5, p. 2030-2039 10 p.

Research output: Contribution to journalArticle

Rectal Neoplasms
Fluorouracil
Radiotherapy
Drug Therapy
Levamisole