Alex Yemelyanov

  • 916 Citations
20012022

Research output per year

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Research Output

  • 916 Citations
  • 24 Article
2018

Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy

Baida, G., Bhalla, P., Yemelyanov, A., Stechschulte, L. A., Shou, W., Readhead, B., Dudley, J. T., Sánchez, E. R. & Budunova, I., Oct 1 2018, In : Oncotarget. 9, 78, p. 34772-34783 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions

Ishiyama, N., Sarpal, R., Wood, M. N., Barrick, S. K., Nishikawa, T., Hayashi, H., Kobb, A. B., Flozak, A. S., Yemelyanov, A., Fernandez-Gonzalez, R., Yonemura, S., Leckband, D. E., Gottardi, C. J., Tepass, U. & Ikura, M., Dec 1 2018, In : Nature communications. 9, 1, 5121.

Research output: Contribution to journalArticle

11 Scopus citations
2017

FXYD5 is an essential mediator of the inflammatory response during lung injury

Brazee, P. L., Soni, P. N., Tokhtaeva, E., Magnani, N., Yemelyanov, A., Perlman, H. R., Ridge, K. M., Sznajder, J. I., Vagin, O. & Dada, L. A., Jun 1 2017, In : Frontiers in immunology. 8, JUN, 623.

Research output: Contribution to journalArticle

8 Scopus citations

Nuclear α-catenin mediates the DNA damage response via β-catenin and nuclear actin

Serebryannyy, L. A., Yemelyanov, A., Gottardi, C. J. & de Lanerolle, P., May 15 2017, In : Journal of cell science. 130, 10, p. 1717-1729 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion

Wood, M. N., Ishiyama, N., Singaram, I., Chung, C. M., Flozak, A. S., Yemelyanov, A., Ikura, M., Cho, W. & Gottardi, C., Nov 1 2017, In : Journal of Cell Biology. 216, 11, p. 3767-3783 17 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Discovery of Compound A - A selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity

Lesovaya, E., Yemelyanov, A., Swart, A. C., Swart, P., Haegeman, G. & Budunova, I., Jan 1 2015, In : Oncotarget. 6, 31, p. 30730-30744 15 p.

Research output: Contribution to journalArticle

23 Scopus citations
2014

α-Catenin is an inhibitor of transcription

Daugherty, R. L., Serebryannyy, L., Yemelyanov, A., Flozak, A. S., Yu, H. J., Kosak, S. T., De Lanerolle, P. & Gottardi, C., Jan 1 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 14, p. 5260-5265 6 p.

Research output: Contribution to journalArticle

24 Scopus citations
2013

Combination of a selective activator of the glucocorticoid receptor Compound A with a proteasome inhibitor as a novel strategy for chemotherapy of hematologic malignancies

Lesovaya, E., Yemelyanov, A., Kirsanov, K., Popa, A., Belitsky, G., Yakubovskaya, M., Gordon, L. I., Rosen, S. T. & Budunova, I., Jan 1 2013, In : Cell Cycle. 12, 1, p. 133-144 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth

Ono, M., Yin, P., Navarro, A., Moravek, M. B., Coon V, J. S., Druschitz, S. A., Serna, V. A., Qiang, W., Brooks, D. C., Malpani, S. S., Ma, J., Ercan, C. M., Mittal, N., Monsivais, D., Dyson, M. T., Yemelyanov, A., Maruyama, T., Chakravarti, D., Kim, J. J., Kurita, T. & 2 others, Gottardi, C. J. & Bulun, S. E., Oct 15 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 17053-17058 6 p.

Research output: Contribution to journalArticle

77 Scopus citations
2012

Androgen receptor drives cellular senescence

Mirochnik, Y., Veliceasa, D., Williams, L., Maxwell, K., Yemelyanov, A., Budunova, I. & Volpert, O. V., Mar 5 2012, In : PloS one. 7, 3, e31052.

Research output: Contribution to journalArticle

29 Scopus citations

Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells: A novel therapeutic modality

Yemelyanov, A., Bhalla, P., Yang, X., Ugolkov, A., Iwadate, K., Karseladze, A. & Budunova, I., Jan 15 2012, In : Cell Cycle. 11, 2, p. 395-406 12 p.

Research output: Contribution to journalArticle

31 Scopus citations
2011

Antitumor effect of non-steroid glucocorticoid receptor ligand CpdA on leukemia cell lines CEM and K562

Lesovaya, E. A., Yemelyanov, A. Y., Kirsanov, K. I., Yakubovskaya, M. G. & Budunova, I. V., Nov 1 2011, In : Biochemistry (Moscow). 76, 11, p. 1242-1252 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
2009

Targeting transcription factor NFκB: Comparative analysis of proteasome and IKK inhibitors

Gasparian, A. V., Guryanova, O. A., Chebotaev, D. V., Shishkin, A. A., Yemelyanov, A. Y. & Budunova, I. V., May 15 2009, In : Cell Cycle. 8, 10, p. 1559-1566 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
2008

Novel steroid receptor phyto-modulator compound a inhibits growth and survival of prostate cancer cells

Yemelyanov, A., Czwornog, J., Gera, L., Joshi, S., Chatterton Jr, R. T. & Budunova, I., Jun 15 2008, In : Cancer Research. 68, 12, p. 4763-4773 11 p.

Research output: Contribution to journalArticle

47 Scopus citations
2007

Androgen receptor targets NFκB and TSP1 to suppress prostate tumor growth in vivo

Nelius, T., Filleur, S., Yemelyanov, A., Budunova, I., Shroff, E., Mirochnik, Y., Aurora, A., Veliceasa, D., Xiao, W., Wang, Z. & Volpert, O. V., Sep 1 2007, In : International Journal of Cancer. 121, 5, p. 999-1008 10 p.

Research output: Contribution to journalArticle

43 Scopus citations
14 Scopus citations

The mechanisms of tumor suppressor effect of glucocorticoid receptor in skin

Chebotaev, D., Yemelyanov, A. & Budunova, I., Aug 1 2007, In : Molecular Carcinogenesis. 46, 8, p. 732-740 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

The tumor suppressor effect of the glucocorticoid receptor in skin is mediated via its effect on follicular epithelial stem cells

Chebotaev, D., Yemelyanov, A., Zhu, L., Lavker, R. M. & Budunova, I., Mar 10 2007, In : Oncogene. 26, 21, p. 3060-3068 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Tumor suppressor activity of glucocorticoid receptor in the prostate

Yemelyanov, A., Czwornog, J., Chebotaev, D., Karseladze, A., Kulevitch, E., Yang, X. & Budunova, I., Mar 22 2007, In : Oncogene. 26, 13, p. 1885-1896 12 p.

Research output: Contribution to journalArticle

88 Scopus citations
2006

Effects of IKK inhibitor PS1145 on NF-κB function, proliferation, apoptosis and invasion activity in prostate carcinoma cells

Yemelyanov, A., Gasparian, A., Lindholm, P., Dang, L., Pierce, J. W., Kisseljov, F., Karseladze, A. & Budunova, I., Jan 19 2006, In : Oncogene. 25, 3, p. 387-398 12 p.

Research output: Contribution to journalArticle

97 Scopus citations
2003

Photophysical Properties of Xanthophylls in Carotenoproteins from Human Retina

Billsten, H. H., Bhosale, P., Yemelyanov, A., Bernstein, P. S. & Polívka, T., Aug 1 2003, In : Photochemistry and Photobiology. 78, 2, p. 138-145 8 p.

Research output: Contribution to journalArticle

45 Scopus citations
2002

Selenium compounds inhibit IκB kinase (IKK) and nuclear factor-κB (NF-κB) in prostate cancer cells

Gasparian, A. V., Yao, Y. J., Lü, J., Yemelyanov, A. Y., Lyakh, L. A., Slaga, T. J. & Budunova, I. V., Oct 1 2002, In : Molecular cancer therapeutics. 1, 12, p. 1079-1087 9 p.

Research output: Contribution to journalArticle

106 Scopus citations

Vitamin A in the cerebrospinal fluid of patients with and without idiopathic intracranial hypertension

Warner, J. E. A., Bernstein, P. S., Yemelyanov, A., Alder, S. C., Farnsworth, S. T. & Digre, K. B., Nov 1 2002, In : Annals of Neurology. 52, 5, p. 647-650 4 p.

Research output: Contribution to journalArticle

52 Scopus citations
2001

Ligand-binding characterization of xanthophyll carotenoids to solubilized membrane proteins derived from human retina

Yemelyanov, A. Y., Katz, N. B. & Bernstein, P. S., Jan 1 2001, In : Experimental eye research. 72, 4, p. 381-392 12 p.

Research output: Contribution to journalArticle

88 Scopus citations