Alexis R Demonbreun

  • 632 Citations
20052024
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Personal profile

Education/Academic qualification

PhD, University of Chicago

… → 2009

Research interests

  • Biologic Therapies
  • Cell Biology
  • Cell Imaging
  • Muscular Dystrophy
  • Neuromuscular Disorders

Fingerprint Dive into the research topics where Alexis R Demonbreun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Muscles Medicine & Life Sciences
Muscular Dystrophies Medicine & Life Sciences
Myoblasts Medicine & Life Sciences
Sarcoglycans Medicine & Life Sciences
Annexin A6 Medicine & Life Sciences
Proteins Medicine & Life Sciences
Membranes Medicine & Life Sciences
Limb-Girdle Muscular Dystrophies Medicine & Life Sciences

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Grants 2014 2024

Annexin A6
Muscles
Muscular Dystrophies
Wounds and Injuries
Membranes
Latent TGF-beta Binding Proteins
Duchenne Muscular Dystrophy
Transforming Growth Factor beta
Carrier Proteins
Steroids
Transforming Growth Factor beta
Carrier Proteins
Fibrosis
Growth
Muscular Dystrophies
Membrane Fusion
Muscles
Annexins
Wounds and Injuries
Phospholipids
Sulfonylurea Receptors
Cardiomyopathies
KATP Channels
Myocardium
Proteins

Research Output 2005 2019

  • 632 Citations
  • 27 Article
  • 3 Review article

A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping

Demonbreun, A. R., Wyatt, E. J., Fallon, K. S., Oosterbaan, C. C., Page, P. G., Hadhazy, M., Quattrocelli, M., Barefield, D. Y. & McNally, E. M., Nov 4 2019, In : Disease models & mechanisms. 13, 2

Research output: Contribution to journalArticle

Open Access
Limb-Girdle Muscular Dystrophies
Exons
Genes
Sarcoglycans
Testing

Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective

Aubert, G., Barefield, D. Y., Demonbreun, A. R., Ramratnam, M., Fallon, K. S., Warner, J. L., Rossi, A. E., Hadhazy, M., Makielski, J. C. & McNally, E. M., Apr 1 2019, In : JACC: Basic to Translational Science. 4, 2, p. 251-268 18 p.

Research output: Contribution to journalArticle

Open Access
Sulfonylurea Receptors
Myocardium
Glucose
Facilitative Glucose Transport Proteins
Glycolysis
3 Citations (Scopus)

Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes

Kim, E. Y., Barefield, D. Y., Vo, A. H., Gacita, A. M., Schuster, E. J., Wyatt, E. J., Davis, J. L., Dong, B., Sun, C., Page, P., Dellefave-Castillo, L., Demonbreun, A., Zhang, H. F. & McNally, E. M., Mar 21 2019, In : JCI Insight. 4, 6, 122686.

Research output: Contribution to journalArticle

Open Access
Myotonic Dystrophy
Cardiac Myocytes
Induced Pluripotent Stem Cells
Nucleotides
Trinucleotide Repeat Expansion
1 Citation (Scopus)

Dusp6 is a genetic modifier of growth through enhanced ERK activity

Vo, A. H., Swaggart, K. A., Woo, A., Gao, Q. Q., Demonbreun, A. R., Fallon, K. S., Quattrocelli, M., Hadhazy, M., Page, P. G. T., Chen, Z., Eskin, A., Squire, K., Nelson, S. F. & McNally, E. M., Jan 15 2019, In : Human molecular genetics. 28, 2, p. 279-289 11 p.

Research output: Contribution to journalArticle

Dual Specificity Phosphatase 6
Extracellular Signal-Regulated MAP Kinases
Muscular Dystrophies
Growth
Myoblasts

Recombinant annexin A6 promotes membrane repair and protects against muscle injury

Demonbreun, A. R., Fallon, K. S., Oosterbaan, C. C., Bogdanovic, E., Warner, J. L., Sell, J. J., Page, P. G., Quattrocelli, M., Barefield, D. Y. & McNally, E. M., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4657-4670 14 p.

Research output: Contribution to journalArticle

Open Access
Annexin A6
Annexins
Muscles
Membranes
Wounds and Injuries