Grants per year
Personal profile
Education/Academic qualification
Developmental Biology, PhD, University of Chicago
… → 2009
Research interests keywords
- Biologic Therapies
- Cell Biology
- Cell Imaging
- Muscular Dystrophy
- Neuromuscular Disorders
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Dive into the research topics where Alexis R Demonbreun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Development of anti-LTBP4 as a biologic to treat Neuromuscular Diseases
Demonbreun, A. R. (PD/PI) & McNally, E. M. (PD/PI)
National Institute of Neurological Disorders and Stroke
6/1/24 → 5/31/26
Project: Research project
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Exploring annexin A6 for the prevention of dystrophic neurites and tau seeding and spreading in Alzheimer's disease
Sadleir, K. R. (PD/PI), Vassar, R. J. (PD/PI), Contractor, A. (Co-Investigator), Demonbreun, A. R. (Co-Investigator) & McNally, E. M. (Co-Investigator)
1/1/24 → 12/31/28
Project: Research project
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Mechanisms of resealing and rebuilding in muscle repair
McNally, E. M. (PD/PI) & Demonbreun, A. R. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
8/3/23 → 4/30/28
Project: Research project
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Extracellular matrix regulation of cellular crosstalk in cardiac fibrosis
Demonbreun, A. R. (PD/PI), McNally, E. M. (PD/PI) & Fullenkamp, D. E. (Co-Investigator)
National Heart, Lung, and Blood Institute
4/1/23 → 3/31/27
Project: Research project
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Understanding and Improving Therapies for the Muscular Dystrophies
McNally, E. M. (PD/PI), McNally, E. M. (PD/PI), Demonbreun, A. R. (Co-Investigator) & Demonbreun, A. R. (Co-Investigator)
University of Florida, National Institute of Arthritis and Musculoskeletal and Skin Diseases
8/1/21 → 7/31/25
Project: Research project
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Physiological stress improves stem cell modeling of dystrophic cardiomyopathy
Fullenkamp, D. E., Willis, A. B., Curtin, J. L., Amaral, A. P., Dittloff, K. T., Harris, S. I., Chychula, I. A., Holgren, C. W., Burridge, P. W., Russell, B., Demonbreun, A. R. & McNally, E. M., Jun 2024, In: DMM Disease Models and Mechanisms. 17, 6, dmm050487.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias
Ohiri, J. C., Dellefave-Castillo, L., Tomar, G., Wilsbacher, L., Choudhury, L., Barefield, D. Y., Fullenkamp, D., Gacita, A. M., Monroe, T. O., Pesce, L., Blancard, M., Vaught, L., George, A. L., Demonbreun, A. R., Puckelwartz, M. J. & McNally, E. M., 2024, In: Journal of the American Heart Association. 13, 10, e030467.Research output: Contribution to journal › Article › peer-review
Open Access -
The extracellular matrix differentially directs myoblast motility and differentiation in distinct forms of muscular dystrophy: Dystrophic matrices alter myoblast motility
Long, A. M., Kwon, J. M., Lee, G. H., Reiser, N. L., Vaught, L. A., O'Brien, J. G., Page, P. G. T., Hadhazy, M., Reynolds, J. C., Crosbie, R. H., Demonbreun, A. R. & McNally, E. M., May 2024, In: Matrix Biology. 129, p. 44-58 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix
O'Brien, J. G., Willis, A. B., Long, A. M., Kwon, J., Lee, G. H., Li, F. W., Page, P. G. T., Vo, A. H., Hadhazy, M., Spencer, M. J., Crosbie, R. H., Demonbreun, A. R. & McNally, E. M., 2024, In: JCI Insight. 9, 3, e173246.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis
Ramachandran, K., Futtner, C. R., Sommars, M. A., Quattrocelli, M., Omura, Y., Fruzyna, E., Wang, J. C., Waldeck, N. J., Senagolage, M. D., Telles, C. G., Demonbreun, A. R., Prendergast, E., Lai, N., Arango, D., Bederman, I. R., McNally, E. M. & Barish, G. D., Feb 2024, In: Nature Metabolism. 6, 2, p. 304-322 19 p.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Waters Demonbreun MDX MRI Manuscript Data Package
Waters, E. (Creator), Haney, C. (Contributor), Vaught, L. (Contributor), McNally, E. (Contributor) & Demonbreun, A. (Contributor), Prism. Galter Health Sciences Library. Northwestern University, May 23 2023
DOI: 10.18131/x17wx-02s47, https://prism.northwestern.edu/doi/10.18131/x17wx-02s47
Dataset
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GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice
Lenhart, K. C. (Creator), O'Neill, T. J. (Contributor), Cheng, Z. (Contributor), Dee, R. (Creator), Demonbreun, A. R. (Creator), Li, J. (Contributor), Xiao, X. (Creator), McNally, E. M. (Creator), Mack, C. P. (Creator), Taylor, J. M. (Creator) & Mack, C. (Creator), figshare, 2015
DOI: 10.6084/m9.figshare.c.3606407, https://figshare.com/collections/GRAF1_deficiency_blunts_sarcolemmal_injury_repair_and_exacerbates_cardiac_and_skeletal_muscle_pathology_in_dystrophin-deficient_mice/3606407
Dataset