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Alexis R Demonbreun

  • 669 Citations
20052024

Research output per year

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Personal profile

Education/Academic qualification

PhD, The University of Chicago

… → 2009

Research interests

  • Biologic Therapies
  • Cell Biology
  • Cell Imaging
  • Muscular Dystrophy
  • Neuromuscular Disorders

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Grants

Recombinant annexin A6 to treat muscle disease and muscle injury

Demonbreun, A. R. & McNally, E. M.

Lakeside Discovery, LLC

4/15/19 → 4/14/24

Project: Research project

    • Assessing high affinity anti-latent TGFbeta binding protein-4 antibodies in combination with steroid treatment for DMD

    Demonbreun, A. R. & McNally, E. M.

    U.S. Army Medical Research and Materiel Command

    8/15/18 → 8/14/21

    Project: Research project

    • Regulating fibrosis and growth through latent TGFbeta binding proteins

    Demonbreun, A. R. & McNally, E. M.

    National Heart, Lung, and Blood Institute

    4/1/18 → 1/31/22

    Project: Research project

    • Myoferlin in muscle membrane fusion and repair

    Demonbreun, A. R. & McNally, E. M.

    National Institute of Neurological Disorders and Stroke

    12/15/17 → 11/30/22

    Project: Research project

    • Myoferlin in muscle membrane fusion and repair

    Demonbreun, A. R. & McNally, E. M.

    National Institute of Neurological Disorders and Stroke

    1/1/15 → 11/30/17

    Project: Research project

    • Research Output

    • 669 Citations
    • 27 Article
    • 3 Review article

    A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping

    Demonbreun, A. R., Wyatt, E. J., Fallon, K. S., Oosterbaan, C. C., Page, P. G., Hadhazy, M., Quattrocelli, M., Barefield, D. Y. & McNally, E. M., Jan 1 2020, In : DMM Disease Models and Mechanisms. 13, 2, dmm040832.

    Research output: Contribution to journal › Article

    Open Access

    • Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective

    Aubert, G., Barefield, D. Y., Demonbreun, A. R., Ramratnam, M., Fallon, K. S., Warner, J. L., Rossi, A. E., Hadhazy, M., Makielski, J. C. & McNally, E. M., Apr 1 2019, In : JACC: Basic to Translational Science. 4, 2, p. 251-268 18 p.

    Research output: Contribution to journal › Article

    Open Access

    • Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes

    Kim, E. Y., Barefield, D. Y., Vo, A. H., Gacita, A. M., Schuster, E. J., Wyatt, E. J., Davis, J. L., Dong, B., Sun, C., Page, P., Dellefave-Castillo, L., Demonbreun, A., Zhang, H. F. & McNally, E. M., Mar 21 2019, In : JCI Insight. 4, 6, 122686.

    Research output: Contribution to journal › Article

    Open Access
    • 3 Scopus citations

    Dusp6 is a genetic modifier of growth through enhanced ERK activity

    Vo, A. H., Swaggart, K. A., Woo, A., Gao, Q. Q., Demonbreun, A. R., Fallon, K. S., Quattrocelli, M., Hadhazy, M., Page, P. G. T., Chen, Z., Eskin, A., Squire, K., Nelson, S. F. & McNally, E. M., Jan 15 2019, In : Human molecular genetics. 28, 2, p. 279-289 11 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Recombinant annexin A6 promotes membrane repair and protects against muscle injury

    Demonbreun, A. R., Fallon, K. S., Oosterbaan, C. C., Bogdanovic, E., Warner, J. L., Sell, J. J., Page, P. G., Quattrocelli, M., Barefield, D. Y. & McNally, E. M., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4657-4670 14 p.

    Research output: Contribution to journal › Article

    Open Access