Grants per year
Personal profile
Education/Academic qualification
PhD, University of Chicago
… → 2009
Research interests
- Biologic Therapies
- Cell Biology
- Cell Imaging
- Muscular Dystrophy
- Neuromuscular Disorders
Fingerprint Dive into the research topics where Alexis R Demonbreun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 8 Similar Profiles
Muscles
Medicine & Life Sciences
Muscular Dystrophies
Medicine & Life Sciences
Myoblasts
Medicine & Life Sciences
Sarcoglycans
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Annexin A6
Medicine & Life Sciences
Membranes
Medicine & Life Sciences
Skeletal Muscle
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2014 2024
Recombinant annexin A6 to treat muscle disease and muscle injury
Demonbreun, A. R. & McNally, E. M.
4/15/19 → 4/14/24
Project: Research project
Annexin A6
Muscles
Muscular Dystrophies
Wounds and Injuries
Membranes
Assessing high affinity anti-latent TGFbeta binding protein-4 antibodies in combination with steroid treatment for DMD
Demonbreun, A. R. & McNally, E. M.
U.S. Army Medical Research and Materiel Command
8/15/18 → 8/14/21
Project: Research project
Latent TGF-beta Binding Proteins
Duchenne Muscular Dystrophy
Transforming Growth Factor beta
Carrier Proteins
Steroids
Regulating fibrosis and growth through latent TGFbeta binding proteins
Demonbreun, A. R. & McNally, E. M.
National Heart, Lung, and Blood Institute
4/1/18 → 1/31/22
Project: Research project
Transforming Growth Factor beta
Carrier Proteins
Fibrosis
Growth
Muscular Dystrophies
Myoferlin in muscle membrane fusion and repair
Demonbreun, A. R. & McNally, E. M.
National Institute of Neurological Disorders and Stroke
12/15/17 → 11/30/22
Project: Research project
Membrane Fusion
Muscles
Annexins
Wounds and Injuries
Phospholipids
Mechanisms of sulfonylurea receptor mediated cardiomyopathy
Castillo, L. M., Demonbreun, A. R. & McNally, E. M.
National Heart, Lung, and Blood Institute
12/1/14 → 11/30/19
Project: Research project
Sulfonylurea Receptors
Cardiomyopathies
KATP Channels
Myocardium
Proteins
Research Output 2005 2019
Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective
Aubert, G., Barefield, D. Y., Demonbreun, A. R., Ramratnam, M., Fallon, K. S., Warner, J. L., Rossi, A. E., Hadhazy, M., Makielski, J. C. & McNally, E. M., Apr 1 2019, In : JACC: Basic to Translational Science. 4, 2, p. 251-268 18 p.Research output: Contribution to journal › Article
Open Access
Sulfonylurea Receptors
Myocardium
Glucose
Facilitative Glucose Transport Proteins
Glycolysis
2
Citations
(Scopus)
Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes
Kim, E. Y., Barefield, D. Y., Vo, A. H., Gacita, A. M., Schuster, E. J., Wyatt, E. J., Davis, J. L., Dong, B., Sun, C., Page, P., Castillo, L. M., Demonbreun, A. R., Zhang, H. F. & McNally, E. M., Mar 21 2019, In : JCI Insight. 4, 6, 122686.Research output: Contribution to journal › Article
Open Access
Myotonic Dystrophy
Cardiac Myocytes
Induced Pluripotent Stem Cells
Nucleotides
Trinucleotide Repeat Expansion
1
Citation
(Scopus)
Dusp6 is a genetic modifier of growth through enhanced ERK activity
Vo, A. H., Swaggart, K. A., Woo, A., Gao, Q. Q., Demonbreun, A. R., Fallon, K. S., Quattrocelli, M., Hadhazy, M., Page, P. G. T., Chen, Z., Eskin, A., Squire, K., Nelson, S. F. & McNally, E. M., Jan 15 2019, In : Human molecular genetics. 28, 2, p. 279-289 11 p.Research output: Contribution to journal › Article
Dual Specificity Phosphatase 6
Extracellular Signal-Regulated MAP Kinases
Muscular Dystrophies
Growth
Myoblasts
1
Citation
(Scopus)
Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers
Wyatt, E. J., Demonbreun, A. R., Kim, E. Y., Roy-Puckelwartz, M. J., Vo, A. H., Castillo, L. M., Gao, Q. Q., Vainzof, M., Pavanello, R. C. M., Zatz, M. & McNally, E. M., May 3 2018, In : JCI insight. 3, 9Research output: Contribution to journal › Article
Open Access
Morpholinos
Exons
Reading Frames
Mutation
Sarcoglycans
4
Citations
(Scopus)
Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury
Quattrocelli, M., Capote, J., Ohiri, J. C., Warner, J. L., Vo, A. H., Earley, J. U., Hadhazy, M., Demonbreun, A. R., Spencer, M. J. & McNally, E. M., Oct 1 2017, In : PLoS genetics. 13, 10, e1007070.Research output: Contribution to journal › Article
muscular dystrophy
modifiers (genes)
Muscular Dystrophies
transforming growth factors
osteopontin