Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Developmental Biology, PhD, University of Chicago
… → 2009
Research interests keywords
- Biologic Therapies
- Cell Biology
- Cell Imaging
- Muscular Dystrophy
- Neuromuscular Disorders
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Dive into the research topics where Alexis R Demonbreun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Understanding and Improving Therapies for the Muscular Dystrophies
McNally, E. M. (PD/PI) & Demonbreun, A. R. (Co-Investigator)
University of Florida, National Institute of Arthritis and Musculoskeletal and Skin Diseases
8/1/24 → 7/31/25
Project: Research project
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Development of anti-LTBP4 as a biologic to treat Neuromuscular Diseases
Demonbreun, A. R. (PD/PI), Demonbreun, A. R. (PD/PI), McNally, E. M. (PD/PI) & McNally, E. M. (PD/PI)
National Institute of Neurological Disorders and Stroke
6/1/24 → 5/31/27
Project: Research project
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Exploring annexin A6 for the prevention of dystrophic neurites and tau seeding and spreading in Alzheimer's disease
Sadleir, K. R. (PD/PI), Vassar, R. J. (PD/PI), Contractor, A. (Co-Investigator), Demonbreun, A. R. (Co-Investigator) & McNally, E. M. (Co-Investigator)
1/1/24 → 12/31/28
Project: Research project
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Mechanisms of resealing and rebuilding in muscle repair
McNally, E. M. (PD/PI) & Demonbreun, A. R. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
8/3/23 → 4/30/28
Project: Research project
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Extracellular matrix regulation of cellular crosstalk in cardiac fibrosis
Demonbreun, A. R. (PD/PI), McNally, E. M. (PD/PI) & Fullenkamp, D. E. (Co-Investigator)
National Heart, Lung, and Blood Institute
4/1/23 → 3/31/27
Project: Research project
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A novel, rapidly progressive ataxia due to a spontaneous Myo5a mutation in mice impairs transport proteins and alters mitochondria
Telenson, A. M., Hsieh, R. R., Cowen, G. J., Sode, E. P., Kwon, J. M., Vo, A. H., Hadhazy, M., Page, P. G., Rao, N. R., Pesce, L., Demonbreun, A. R., Puckelwartz, M. J., Savas, J. N. & McNally, E. M., Mar 15 2025, In: FASEB Journal. 39, 5, e70423.Research output: Contribution to journal › Article › peer-review
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Explaining Racial and Ethnic Inequities in SARS-CoV-2-Related Outcomes: Results from a Serosurvey in Chicago
Eyo, C. A., Schrock, J. M., Hayford, C., Ryan, D. T., Saber, R., Benbow, N., Newcomb, M. E., Demonbreun, A. R., McNally, E. M., D’Aquila, R. T., McDade, T. W. & Mustanski, B., 2025, (Accepted/In press) In: Journal of Racial and Ethnic Health Disparities. e1003402.Research output: Contribution to journal › Article › peer-review
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Distribution of MRI-derived T2 values as a biomarker for in vivo rapid screening of phenotype severity in mdx mice
Waters Hayashi, E. A., Haney, C. R., Vaught, L. A., McNally, E. M. & Demonbreun, A. R., Sep 2024, In: PloS one. 19, 9 September, e0310551.Research output: Contribution to journal › Article › peer-review
Open Access -
Physiological stress improves stem cell modeling of dystrophic cardiomyopathy
Fullenkamp, D. E., Willis, A. B., Curtin, J. L., Amaral, A. P., Dittloff, K. T., Harris, S. I., Chychula, I. A., Holgren, C. W., Burridge, P. W., Russell, B., Demonbreun, A. R. & McNally, E. M., Jun 2024, In: DMM Disease Models and Mechanisms. 17, 6, dmm050487.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias
Ohiri, J. C., Dellefave-Castillo, L., Tomar, G., Wilsbacher, L., Choudhury, L., Barefield, D. Y., Fullenkamp, D., Gacita, A. M., Monroe, T. O., Pesce, L., Blancard, M., Vaught, L., George, A. L., Demonbreun, A. R., Puckelwartz, M. J. & McNally, E. M., 2024, In: Journal of the American Heart Association. 13, 10, e030467.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Datasets
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Waters Demonbreun MDX MRI Manuscript Data Package
Haney, C. R. (Contributor), McNally, E. M. (Contributor), Demonbreun, A. R. (Contributor), Vaught, L. A. (Contributor) & Waters, E. A. (Creator), Prism. Galter Health Sciences Library. Northwestern University, May 23 2023
DOI: 10.18131/e7q8y-8ps35, https://prism.northwestern.edu/doi/10.18131/e7q8y-8ps35
Dataset
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Waters Demonbreun MDX MRI Manuscript Data Package
Waters, E. (Creator), Haney, C. (Contributor), Vaught, L. (Contributor), McNally, E. (Contributor) & Demonbreun, A. (Contributor), Prism. Galter Health Sciences Library. Northwestern University, May 23 2023
DOI: 10.18131/x17wx-02s47, https://prism.northwestern.edu/doi/10.18131/x17wx-02s47
Dataset
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GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice
Lenhart, K. C. (Creator), O'Neill, T. J. (Contributor), Cheng, Z. (Creator), Dee, R. (Creator), Demonbreun, A. R. (Creator), Li, J. (Creator), Xiao, X. (Creator), McNally, E. M. (Creator), Mack, C. P. (Creator) & Taylor, J. M. (Creator), figshare, 2015
DOI: 10.6084/m9.figshare.c.3606407, https://springernature.figshare.com/collections/GRAF1_deficiency_blunts_sarcolemmal_injury_repair_and_exacerbates_cardiac_and_skeletal_muscle_pathology_in_dystrophin-deficient_mice/3606407
Dataset