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Ali Shilatifard

  • 20696 Citations
1991 …2024
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Personal profile

Education/Academic qualification

PhD, University of Oklahoma

… → 1994

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Histones Medicine & Life Sciences
RNA Polymerase II Medicine & Life Sciences
Methylation Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Peptide Elongation Factors Medicine & Life Sciences
Histone Code Medicine & Life Sciences
Lysine Medicine & Life Sciences
Genes Medicine & Life Sciences

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Grants 2014 2024

Super Elongation Complex Disruptors for Cancer Therapeutics

Shilatifard, A.

Lakeside Discovery, LLC

4/15/19 → 4/14/24

Project: Research project

Intellectual Property
Licensure
Cell Proliferation
Survival
Neoplasms

Exploring novel regulatory mechanisms underlying enhancer activation and cell fate transition

Shilatifard, A.

National Institute of Child Health and Human Development

3/11/19 → 2/28/21

Project: Research project

Research Personnel
Epigenomics
Mentors
Stem Cells
Methylation

Structure and Function of the SS18-SSX-containing mSWI/SNF (BAF) Complex Unveiling New Paths Toward Therapeutic Targeting

Shilatifard, A. & Morgan, M. A.

Dana Farber Cancer Institute, National Cancer Institute

9/18/18 → 6/30/23

Project: Research project

Epigenetic Regulation by Histone Modifiers in Development and Cancer

Shilatifard, A.

National Cancer Institute

9/7/18 → 8/31/20

Project: Research project

Embryonic Stem Cells
Epigenomics
Histones
Methylation
Neoplasms

Shilatifard - EFRI CEE Subproject for Institution # SP0048492

Shilatifard, A.

University of Chicago, National Science Foundation

9/1/18 → 8/31/22

Project: Research project

Epigenomics
Optical Imaging
Transcriptional Activation
Drosophila
Chromatin

Research Output 1991 2019

Correction: Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomes (Oncotarget (2018) 9 (37112-37124) DOI: 10.18632/oncotarget.26430)

Huang, T., Garcia, R., Qi, J., Lulla, R., Horbinski, C. M., Behdad, A., Wadhwani, N. R., Shilatifard, A., James, C. D. & Saratsis, A. M., Apr 12 2019, In : Oncotarget. 10, 28, 1 p.

Research output: Contribution to journal › Comment/debate

Open Access
Post Translational Protein Processing
Glioma
Histones
Immunohistochemistry
Pediatrics

Correction to: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity (Nature Communications, (2018), 9, 1, (4406), 10.1038/s41467-018-06543-0)

Chung, C. Y., Berson, A., Kennerdell, J. R., Sartoris, A., Unger, T., Porta, S., Kim, H. J., Smith, E., Shilatifard, A., Van Deerlin, V., Lee, V. M. Y., Chen-Plotkin, A. & Bonini, N. M., Dec 1 2019, In : Nature communications. 10, 1, 555.

Research output: Contribution to journal › Comment/debate

document markup languages
neurology
Untranslated RNA
HTML
Neurology
1 Citation (Scopus)

Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia

Zhao, Z., Wang, L., Volk, A. G., Birch, N. W., Stoltz, K. L., Bartom, E. T., Marshall, S. A., Rendleman, E. J., Nestler, C. M., Shilati, J., Schiltz, G. E., Crispino, J. D. & Shilatifard, A., Jan 1 2019, In : Genes and Development. 33, 1-2, p. 61-74 14 p.

Research output: Contribution to journal › Article

Aspartate Ammonia-Lyase
Threonine
Leukemia
Casein Kinase II
Therapeutics

The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity–independent genomic targeting

Pan, J., McKenzie, Z. M., D’Avino, A. R., Mashtalir, N., Lareau, C. A., St. Pierre, R., Wang, L., Shilatifard, A. & Kadoch, C., Jan 1 2019, In : Nature Genetics.

Research output: Contribution to journal › Letter

Adenosine Triphosphatases
Sucrose
Small Cell Carcinoma
Chromatin
Ovary
2 Citations (Scopus)

USP7 cooperates with NOTch1 to drive the oncogenic transcriptional program in T-cell leukemia

Jin, Q., Martinez, C. A., Arcipowski, K. M., Zhu, Y., Gutierrez-Diaz, B. T., Wang, K. K., Johnson, M. R., Volk, A. G., Wang, F., Wu, J., Grove, C., Wang, H., Sokirniy, I., Thomas, P. M., Goo, Y. A., Abshiru, N. A., Hijiya, N., Peirs, S., Vandamme, N., Berx, G. & 27 othersGoosens, S., Marshall, S. A., Rendleman, E. J., Takahashi, Y., Wang, L., Rawat, R., Bartom, E. T., Collings, C. K., Van Vlierberghe, P., Strikoudis, A., Kelly, S., Ueberheide, B., Mantis, C., Kandela, I., Bourquin, J. P., Bornhauser, B., Serafin, V., Bresolin, S., Paganin, M., Accordi, B., Basso, G., Kelleher, N. L., Weinstock, J., Kumar, S., Crispino, J. D., Shilatifard, A. & Ntziachristos, P., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 222-239 18 p.

Research output: Contribution to journal › Article

Open Access
Ubiquitin-Specific Proteases
T-Cell Leukemia
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Chromatin