Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Biochemistry, University of Oklahoma
… → 1994
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Collaborations and top research areas from the last five years
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Therapeutic targeting of esophageal tumors with MLL4 or UTX mutations
Shilatifard, A. (PD/PI) & Zhao, Z. (Co-Investigator)
Mark Foundation for Cancer Research (US) Ltd
1/1/25 → 12/31/25
Project: Research project
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Targeting SPOP and BRD4 to Blunt the Toxicity of C9ORF72-Derived Dipeptide Repeat Proteins
Kalb, R. G. (PD/PI), Kalb, R. G. (PD/PI), Shilatifard, A. (Other) & Shilatifard, A. (Other)
U.S. Army Medical Research and Materiel Command
9/15/24 → 9/14/26
Project: Research project
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Uncovering Signal-Specific Inflammatory Responses in 3D Tumor Microenvironments Utilizing FIT SNA Nanoprobes - Shilatifard
Shilatifard, A. (Co-PD/PI)
6/1/24 → 5/31/27
Project: Research project
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Sub-project for Ali Shilatifard
Shilatifard, A. (PD/PI)
National Institute of Allergy and Infectious Diseases
8/10/23 → 7/31/25
Project: Research project
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Correction to: Profibrotic monocyte-derived alveolar macrophages are expanded in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19 (Nature Immunology, (2024), 25, 11, (2097-2109), 10.1038/s41590-024-01975-x)
Bailey, J. I., Puritz, C. H., Senkow, K. J., Markov, N. S., Diaz, E., Jonasson, E., Yu, Z., Swaminathan, S., Lu, Z., Fenske, S., Grant, R. A., Abdala-Valencia, H., Mylvaganam, R. J., Ludwig, A., Miller, J., Cumming, R. I., Tighe, R. M., Gowdy, K. M., Kalhan, R. & Jain, M. & 12 others, , Feb 2025, In: Nature Immunology. 26, 2, p. 323 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Ectopic expression of testis-specific transcription elongation factor in driving cancer
Zheng, B., Iwanaszko, M., Soliman, S. H. A. A., Ishi, Y., Gold, S., Qiu, R., Howard, B. C., Das, M., Zhao, Z., Hashizume, R., Wang, L. & Shilatifard, A., Mar 14 2025, In: Science Advances. 11, 11, eads4200.Research output: Contribution to journal › Article › peer-review
Open Access -
Purifying and profiling lysosomes to expand understanding of lysosomal dysfunction–associated diseases
Shilatifard, A. & Ben-Sahra, I., Feb 17 2025, In: Journal of Clinical Investigation. 135, 4, e188507.Research output: Contribution to journal › Review article › peer-review
Open Access -
SPT5 regulates RNA polymerase II stability via Cullin 3-ARMC5 recognition
Aoi, Y., Iravani, L., Mroczek, I. C., Gold, S., Howard, B. C. & Shilatifard, A., Jan 24 2025, In: Science Advances. 11, 4, eadt5885.Research output: Contribution to journal › Article › peer-review
Open Access -
Cytoplasmic transcription factor sequestration drives the pathogenesis of a rearranged leukemia
Shilatifard, A., Feb 15 2024, In: Journal of Clinical Investigation. 134, 4, 179105.Research output: Contribution to journal › Editorial › peer-review
Open Access
Datasets
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Crystal structure of DPY-30 dimerization/docking domain in complex with Ash2L Sdc1-DPY-30 Interacting region (SDI)
Tremblay, V. (Contributor), Zhang, P. (Contributor), Chaturvedi, C.-P. (Contributor), Thornton, J. (Contributor), Brunzelle, J. S. (Contributor), Skiniotis, G. (Contributor), Shilatifard, A. (Contributor), Brand, M. (Contributor) & Couture, J.-F. (Contributor), Protein Data Bank (PDB), Dec 17 2014
DOI: 10.2210/pdb4RIQ/pdb, https://www.wwpdb.org/pdb?id=pdb_00004riq
Dataset
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Crystal structure of RbBP5 interacting domain of Cfp1
Yang, Y. (Contributor), Joshi, M. (Contributor), Takahashi, Y.-H. (Contributor), Ning, Z. (Contributor), Qu, Q. (Contributor), Brunzelle, J. S. (Contributor), Skiniotis, G. (Contributor), Figeys, D. (Contributor), Shilatifard, A. (Contributor) & Couture, J.-F. (Contributor), Protein Data Bank (PDB), Jan 22 2020
DOI: 10.2210/pdb6VHF/pdb, https://www.wwpdb.org/pdb?id=pdb_00006vhf
Dataset
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Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30
Haddad, J. F. (Contributor), Yang, Y. (Contributor), Takahashi, Y.-H. (Contributor), Joshi, M. (Contributor), Chaudhary, N. (Contributor), Woodfin, A. R. (Contributor), Benyoucef, A. (Contributor), Yeung, S. (Contributor), Brunzelle, J. S. (Contributor), Skiniotis, G. (Contributor), Brand, M. (Contributor), Shilatifard, A. (Contributor) & Couture, J.-F. (Contributor), Protein Data Bank (PDB), Aug 8 2018
DOI: 10.2210/pdb6E2H/pdb, https://www.wwpdb.org/pdb?id=pdb_00006e2h
Dataset
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Therapeutic targeting MLL degradation pathways in MLL-rearranged leukemia
Liang, K. (Contributor), Smith, E. R. (Contributor) & Shilatifard, A. (Contributor), Gene Expression Omnibus, Nov 3 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE89485
Dataset
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An epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS
Rickels, R. (Contributor), Hu, D. (Contributor), Piunti, A. (Contributor), Mohan, M. (Contributor), Kvon, E. (Contributor) & Shilatifard, A. (Contributor), ArrayExpress, 2016
https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-81795
Dataset