Grants per year
Personal profile
Research Interests
Identifying and investigating novel molecular bases of cellular recognition that control neuronal circuit assembly during human development and disease. To explore the broader roles for cell recognition molecules and their pivotal function in neural circuit development, our lab takes advantage of a battery of modern laboratory techniques. These approaches include animal and stem cell disease modeling, as well as next-generation sequencing and CRISPR/Cas9 gene editing.
Education/Academic qualification
Biomedical Sciences, PhD, Universidad Nacional Autónoma de México
… → 2010
Research interests
- Developmental Neurobiology
- Epilepsy
- Neurogenetics
- Neuroscience
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Grants
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Human forebrain organoids to model PACS1 Syndrome
PACS1 Syndrome Research Foundation
5/15/19 → 7/25/21
Project: Research project
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Uncovering altered connectivity in epilepsy due to somatic mutations
9/1/19 → 8/31/20
Project: Research project
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Role of PCDH12 in neural circuit formation during brain development and disease
National Institute of Neurological Disorders and Stroke
6/1/17 → 5/31/20
Project: Research project
Research Output
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Characterization of seizure susceptibility in Pcdh19 mice
Rakotomamonjy, J., Sabetfakhri, N. P., McDermott, S. L. & Guemez-Gamboa, A., Oct 2020, In: Epilepsia. 61, 10, p. 2313-2320 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
PYRC2-Related Hypomyelinating Leukodystrophy: More to This Than Meets the Eye
Rakotomamonjy, J., Rylaarsdam, L. & Guemez-Gamboa, A., Jul 8 2020, In: Neuron. 107, 1, p. 3-5 3 p.Research output: Contribution to journal › Article › peer-review
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Genetic Causes and Modifiers of Autism Spectrum Disorder
Rylaarsdam, L. & Guemez-Gamboa, A., Aug 20 2019, In: Frontiers in Cellular Neuroscience. 13, 385.Research output: Contribution to journal › Review article › peer-review
Open Access39 Scopus citations -
Purkinje cell survival in organotypic cerebellar slice cultures
Rakotomamonjy, J. & Guemez-Gamboa, A., Dec 2019, In: Journal of Visualized Experiments. 2019, 154, e60353.Research output: Contribution to journal › Article › peer-review
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Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors
Li, H., Saucedo-Cuevas, L., Yuan, L., Ross, D., Johansen, A., Sands, D., Stanley, V., Guemez Gamboa, A. D., Gregor, A., Evans, T., Chen, S., Tan, L., Molina, H., Sheets, N., Shiryaev, S. A., Terskikh, A. V., Gladfelter, A. S., Shresta, S., Xu, Z. & Gleeson, J. G., Mar 20 2019, In: Neuron. 101, 6, p. 1089-1098.e4Research output: Contribution to journal › Article › peer-review
20 Scopus citations