Amanda Muhs Saratsis

  • 365 Citations
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Personal profile

Research Interests

Dr. Saratsis has clinical appointments in the Departments of Neurological Surgery at Northwestern Memorial and Lurie Children's Hospitals, caring for children and adults with congenital disorders of the central nervous system. Dr. Saratsis has expertise in the clinical management and molecular biology of pediatric brain tumors, with particular focus on pediatric high-grade and brainstem glioma. Dr. Saratsis's laboratory aims to characterize the molecular biology of pediatric brain tumors for indentification of biomarkers of disease and development of novel, targeted therapeutic approaches to improve clinical outcomes. Dr. Saratsis is involved in multiple laboratory and clinical studies for development and clinical trial of new treatments for children with brain tumors, working closely with the neurosurgery and neuro-oncology clinical and research teams at Northwestern University and Lurie Children’s.

Training Experience

2007Internship, Georgetown University Hospital
2007Residency, University of California, Irvine
2012Residency, Georgetown University Hospital
2012Residency, Georgetown University Hospital
2014Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital)

Education/Academic qualification

MD, University of Illinois - Chicago

… → 2006

Research interests

  • Brain Cancer / Nervous System Cancer
  • Cancer Biology
  • Cancer Genetics
  • Neurosurgery

Fingerprint Dive into the research topics where Amanda Muhs Saratsis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Glioma Medicine & Life Sciences
Pediatrics Medicine & Life Sciences
Mutation Medicine & Life Sciences
Histones Medicine & Life Sciences
Cerebrospinal Fluid Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Post Translational Protein Processing Medicine & Life Sciences
Brain Neoplasms Medicine & Life Sciences

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Grants 2015 2021

Research Output 2011 2019

Choroidal artery embolization in the management of cerebrospinal fluid overproduction: Case report and review of the literature

Li, D., Shokuhfar, T., Pantalone, J., Rothstein, B., Alden, T. D., Shaibani, A. & Saratsis, A. M., Jun 1 2019, In : Journal of Neurosurgery: Pediatrics. 23, 6, p. 737-748 12 p.

Research output: Contribution to journalReview article

Choroid Plexus
Cerebrospinal Fluid
Open Access
Post Translational Protein Processing
2 Citations (Scopus)

Methylation-dependent Tissue Factor Suppression Contributes to the Reduced Malignancy of IDH1-mutant Gliomas

Unruh, D., Mirkov, S., Wray, B., Drumm, M., Lamano, J., Li, Y. D., Haider, Q. F., Javier, R., McCortney, K., Saratsis, A., Scholtens, D. M., Sarkaria, J. N., David James, C. & Horbinski, C., Jan 15 2019, In : Clinical Cancer Research. 25, 2, p. 747-759 13 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase

Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease

Qi, J., Esfahani, D. R., Huang, T., Ozark, P., Bartom, E. T., Hashizume, R., Bonner, E. R., An, S., Horbinski, C. M., James, C. D. & Saratsis, A. M., May 15 2019, In : Acta Neuropathologica Communications. 7, 1, 75.

Research output: Contribution to journalArticle

Open Access
Brain Stem Neoplasms
Post Translational Protein Processing