Dr. Saratsis has clinical appointments in the Departments of Neurological Surgery at Northwestern Memorial and Lurie Children's Hospitals, caring for children and adults with congenital disorders of the central nervous system. Dr. Saratsis has expertise in the clinical management and molecular biology of pediatric brain tumors, with particular focus on pediatric high-grade and brainstem glioma. Dr. Saratsis's laboratory aims to characterize the molecular biology of pediatric brain tumors for indentification of biomarkers of disease and development of novel, targeted therapeutic approaches to improve clinical outcomes. Dr. Saratsis is involved in multiple laboratory and clinical studies for development and clinical trial of new treatments for children with brain tumors, working closely with the neurosurgery and neuro-oncology clinical and research teams at Northwestern University and Lurie Children’s.