Amy Leanne Walz

  • 173 Citations
20152019
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Personal profile

Research Interests

I received my medical degree from the University of Louisville School of Medicine in 2005, prior to completing my Pediatrics residency at the University of Texas Southwestern/Children's Medical Center Dallas. I completed a fellowship in Pediatric Hematology/Oncology in 2015 and a fellowship in Developmental Therapeutics in 2016 at McGaw Medical Center of Northwestern University/Ann & Robert H. Lurie Children's Hospital of Chicago. I subsequently became a member of the Pediatric Hematology/Oncology division at Ann & Robert H. Lurie Children's Hospital of Chicago in July 2016.

My research interests involve the study of pediatric high-risk renal tumors and their underlying genetic drivers. As a member of the Children's Oncology Group's Renal Tumor Committee and the Pediatric Preclinical Testing Consortium Disease Committee, I participate in the development of new therapeutic clinical trials, including early phase clinical trials, for renal tumor patients. I was recently named as the Developmental Therapeutics lead for the Renal Tumor Committee. In addition, I am also focused on analysis of circulating exosomes from pediatric solid tumor patients as biomarkers for use in diagnosis, monitoring of treatment response, and early detection of relapse.

My clinical focus centers on the treatment of pediatric solid tumor patients, including those with renal tumors, liver tumors, germ cell tumors, and sarcomas. Through my work with the Children's Oncology Group's Renal Disease Committee, I participate in the development of new therapeutic clinical trials for renal tumor patients. I was recently named as the Developmental Therapeutics lead for the Renal Tumor Committee. I am also involved in the Fertility and Hormone Preservation and Restoration Program, which provides counseling and fertility preservation options to patients receiving treatments that are likely to impact their future reproductive potential.

Training Experience

2012Residency, University of Texas Southwestern Medical School, Dallas
2015Fellowship, Northwestern University, McGaw Medical Center (Lurie Children's Hospital)
2016Fellowship, Northwestern University, McGaw Medical Center (Lurie Children's Hospital)

Education/Academic qualification

MD, University of Louisville

… → 2005

Research interests

  • Bone / Cartilage Cancer
  • Kidney Cancer / Urinary Tract Cancer
  • Molecular Diagnostics
  • Pediatric Non-sarcoma solid tumors and Fertility Preservation
  • Translational Research

Fingerprint Dive into the research topics where Amy Leanne Walz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Wilms Tumor Medicine & Life Sciences
Cryopreservation Medicine & Life Sciences
Mutation Medicine & Life Sciences
Fertility Preservation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Anaplasia Medicine & Life Sciences
Thrombasthenia Medicine & Life Sciences
Glycogen Synthase Kinase 3 Medicine & Life Sciences

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Research Output 2015 2019

  • 173 Citations
  • 9 Article
  • 1 Comment/debate
1 Citation (Scopus)

Laparoscopic unilateral oophorectomy for ovarian tissue cryopreservation in children

Rowell, E., Corkum, K. S., Lautz, T. B., Laronda, M. M., Walz, A. L., Madonna, M. B., Lockart, B. A. & Reynolds, M., Mar 1 2019, In : Journal of pediatric surgery. 54, 3, p. 543-549 7 p.

Research output: Contribution to journalArticle

Cryopreservation
Ovariectomy
Infertility
Therapeutics
Fertility Preservation

Testicular wedge biopsy for fertility preservation in children at significant risk for azoospermia after gonadotoxic therapy

Corkum, K. S., Lautz, T. B., Johnson, E. K., Reimann, M. B., Walz, A. L., Lockart, B. A., Brannigan, R. E., ValliPulaski, H., Orwig, K. E. & Rowell, E., Sep 1 2019, In : Journal of pediatric surgery. 54, 9, p. 1901-1905 5 p.

Research output: Contribution to journalArticle

Fertility Preservation
Azoospermia
Cryopreservation
Biopsy
Therapeutics

Malignant Rhabdoid Tumor

Geller, JI. & Walz, AL., Oct 9 2018, In : eMedicine from WebMD available at https://emedicine.medscape.com/article/993084-overview.

Research output: Contribution to journalArticle

Prolonged response to sorafenib in a patient with refractory metastatic osteosarcoma and a somatic PDGFRA D846V mutation

Armstrong, A. E., Walterhouse, D. O., Leavey, P. J., Reichek, J. & Walz, A. L., Jan 1 2018, (Accepted/In press) In : Pediatric Blood and Cancer. 66, 1, e27493.

Research output: Contribution to journalArticle

Osteosarcoma
Mutation
Biomarkers
Recurrence
Terminology
44 Citations (Scopus)

A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor

Gadd, S. L., Huff, V., Walz, A. L., Ooms, A. H. A. G., Armstrong, A. E., Gerhard, D. S., Smith, M. A., Guidry Auvil, J. M., Meerzaman, D., Chen, Q. R., Hsu, C. H., Yan, C., Nguyen, C., Hu, Y., Hermida, L. C., Davidsen, T., Gesuwan, P., Ma, Y., Zong, Z., Mungall, A. J. & 11 others, Moore, R. A., Marra, M. A., Dome, J. S., Mullighan, C. G., Ma, J., Wheeler, D. A., Hampton, O. A., Ross, N., Gastier-Foster, J. M., Arold, S. T. & Perlman, E. J., Oct 1 2017, In : Nature Genetics. 49, 10, p. 1487-1494 8 p.

Research output: Contribution to journalArticle

Wilms Tumor
DNA Copy Number Variations
DNA Methylation
MicroRNAs
Genes