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Dive into the research topics where Anan Yu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Drug Discovery to Ameliorate Proteostasis Failure in Tauopathies
Morimoto, R. I., Morimoto, R. I., Yu, A. & Yu, A.
Rainwater Charitable Foundation
6/19/20 → 7/31/24
Project: Research project
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Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
Capano, L. S., Sato, C., Ficulle, E., Yu, A., Horie, K., Kwon, J. S., Burbach, K. F., Barthélemy, N. R., Fox, S. G., Karch, C. M., Bateman, R. J., Houlden, H., Morimoto, R. I., Holtzman, D. M., Duff, K. E. & Yoo, A. S., Jun 2 2022, In: Cell stem cell. 29, 6, p. 918-932.e8Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Challenging Proteostasis: Role of the Chaperone Network to Control Aggregation-Prone Proteins in Human Disease
Sinnige, T., Yu, A. & Morimoto, R. I., 2020, Advances in Experimental Medicine and Biology. Springer, p. 53-68 16 p. (Advances in Experimental Medicine and Biology; vol. 1243).Research output: Chapter in Book/Report/Conference proceeding › Chapter
24 Scopus citations -
Tau protein aggregates inhibit the protein-folding and vesicular trafficking arms of the cellular proteostasis network
Yu, A., Fox, S. G., Cavallini, A., Kerridge, C., O'Neill, M. J., Wolak, J., Bose, S. & Morimoto, R. I., May 10 2019, In: Journal of Biological Chemistry. 294, 19, p. 7917-7930 14 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Key interactions for clathrin coat stability
Böcking, T., Aguet, F., Rapoport, I., Banzhaf, M., Yu, A., Zeeh, J. C. & Kirchhausen, T., Jun 10 2014, In: Structure. 22, 6, p. 819-829 11 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition
Yu, A., Shibata, Y., Shah, B., Calamini, B., Lo, D. C. & Morimoto, R. I., Apr 15 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 15, p. E1481-E1490Research output: Contribution to journal › Article › peer-review
107 Scopus citations