Andrew Christian Larson

  • 4650 Citations
19992023
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Personal profile

Research Interests

Currently my research focuses on the development and validation of magnetic resonance imaging techniques for optimal delivery and functional guidance of minimally invasive therapies, early prediction of therapy response, and non-invasive staging of carcinogenesis. My most recent efforts are focused on the development of imaging methods for primary and metastatic tumors of the liver. Our group deliberately emphasizes a bench-to-bedside translational approach to research. Working closely with a multi-disciplinary group of clinical collaborators, methods first developed and validated in phantoms and animal models are rapidly translated to the clinical setting at Northwestern Memorial Hospital.

Education/Academic qualification

PhD, Northwestern University

… → 2004

Keywords

  • Fibrosis
  • Liver Cancer
  • Oncology

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Magnetic Resonance Imaging Medicine & Life Sciences
Liver Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Tumors Chemical Compounds
Hepatocellular Carcinoma Medicine & Life Sciences
Rabbits Medicine & Life Sciences
Magnetic Resonance Angiography Medicine & Life Sciences
Electroporation Medicine & Life Sciences

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Grants 2003 2023

MTIC CH Shared Resource

Larson, A. C.

National Cancer Institute

8/10/187/31/23

Project: Research project

5-(3-methyl-1-triazeno)imidazole-4-carboxamide
Neoplasms
Medicine
Research
Ethiodized Oil
Microspheres
Angiogenesis Inhibitors
Doxorubicin
Rodentia
Pancreatic Neoplasms
Immunotherapy
Dendritic Cells
Vaccines
Magnetic Resonance Imaging

Research Output 1999 2019

Correction: Validation of near infrared fluorescence (NIRF) probes in vivo with dual laser NIRF endoscope (PLoS One (2018) 13:11 (e0206568) DOI: 10.1371/journal.pone.0206568)

Shrivastav, M., Gounaris, E., Khan, M. W., Ko, J., Ryu, S. H., Bogyo, M., Larson, A. C., Barrett, T. A. & Bentrem, D. J., Jan 1 2019, In : PloS one. 14, 1, e0210677.

Research output: Contribution to journalComment/debate

Open Access
endoscopes
Endoscopy
Endoscopes
probes (equipment)
Names

Iron-Oxide Nanocluster Labeling of Clostridium novyi-NT Spores for MR Imaging–Monitored Locoregional Delivery to Liver Tumors in Rat and Rabbit Models

Ji, J., Park, W. R., Cho, S., Yang, Y., Li, W., Harris, K., Huang, X., Gu, S., Kim, D-H., Zhang, Z. & Larson, A. C., Jul 1 2019, In : Journal of Vascular and Interventional Radiology. 30, 7, p. 1106-1115.e1

Research output: Contribution to journalArticle

Clostridium
Spores
Magnetic Resonance Spectroscopy
Rabbits
Liver

18F-FDG PET biomarkers help detect early metabolic response to irreversible electroporation and predict therapeutic outcomes in a rat liver tumor model

Wang, X., Su, Z., Lyu, T., Figini, M., Procissi, D., Shangguan, J., Sun, C., Wang, B., Shang, N., Gu, S., Ma, Q., Gordon, A. C., Lin, K., Wang, J., Lewandowski, R. J., Salem, R., Yaghmai, V., Larson, A. C. & Zhang, Z., Apr 1 2018, In : Radiology. 287, 1, p. 137-145 9 p.

Research output: Contribution to journalArticle

Electroporation
Fluorodeoxyglucose F18
Positron-Emission Tomography
Biomarkers
Liver
2 Citations (Scopus)

Early Immunologic Response of Irreversible Electroporation versus Cryoablation in a Rodent Model of Pancreatic Cancer

White, S. B., Zhang, Z., Chen, J., Gogineni, V. R. & Larson, A. C., Dec 1 2018, In : Journal of Vascular and Interventional Radiology. 29, 12, p. 1764-1769 6 p.

Research output: Contribution to journalArticle

Cryosurgery
Electroporation
Pancreatic Neoplasms
Rodentia
Neoplasms