• 112 Citations
20142020
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Research Output 2014 2019

  • 112 Citations
  • 10 Article
  • 1 Chapter
2019
3 Citations (Scopus)

A review of the clinical pharmacokinetics of polymyxin b

Avedissian, S. N., Liu, J., Rhodes, N. J., Lee, A., Pais, G. M., Hauser, A. R. & Scheetz, M. H., Mar 1 2019, In : Antibiotics. 8, 1, 31.

Research output: Contribution to journalArticle

Open Access
Polymyxins
Polymyxin B
Pharmacokinetics
Colistin
Toxicity
3 Citations (Scopus)

Exploration of the nanomedicine-design space with high-throughput screening and machine learning

Yamankurt, G., Berns, E. J., Xue, A., Lee, A., Bagheri, N., Mrksich, M. & Mirkin, C. A., Apr 1 2019, In : Nature Biomedical Engineering. 3, 4, p. 318-327 10 p.

Research output: Contribution to journalArticle

Nanomedicine
Medical nanotechnology
Nucleic acids
Nucleic Acids
Learning systems
4 Citations (Scopus)

IDH3α regulates one-carbon metabolism in glioblastoma

May, J. L., Kouri, F., Hurley, L. A., Liu, J., Tommasini-Ghelfi, S., Ji, Y., Gao, P., Calvert, A. E., Lee, A., Chandel, N., Davuluri, R. V., Horbinski, C. M., Locasale, J. W. & Stegh, A. H., Jan 1 2019, In : Science Advances. 5, 1, eaat0456.

Research output: Contribution to journalArticle

Glioblastoma
Glycine Hydroxymethyltransferase
Carbon
Methionine
Activity Cycles
1 Citation (Scopus)

Manipulating immune activation of macrophages by tuning the oligonucleotide composition of gold nanoparticles

Pallares, R. M., Choo, P., Cole, L. E., Mirkin, C. A., Lee, A. & Odom, T. W., Jul 17 2019, In : Bioconjugate Chemistry. 30, 7, p. 2032-2037 6 p.

Research output: Contribution to journalArticle

Macrophage Activation
Macrophages
Oligonucleotides
Gold
Nanoparticles
1 Citation (Scopus)

Rational vaccinology with spherical nucleic acids

Wang, S., Qin, L., Yamankurt, G., Skakuj, K., Huang, Z., Chen, P. C., Dominguez, D., Lee, A., Zhang, B. & Mirkin, C. A., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10473-10481 9 p.

Research output: Contribution to journalArticle

Nucleic Acids
Neoplasms
Nanostructures
Antigens
Vaccination

Synthesis, physicochemical, and biological evaluation of spherical nucleic acids for RNAi-based therapy in glioblastoma

Tommasini-Ghelfi, S., Lee, A., Mirkin, C. A. & Stegh, A. H., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc, p. 371-391 21 p. (Methods in Molecular Biology; vol. 1974).

Research output: Chapter in Book/Report/Conference proceedingChapter

Glioblastoma
Nucleic Acids
MicroRNAs
Brain Neoplasms
Small Interfering RNA
2018
13 Citations (Scopus)

Conjugation Chemistry-Dependent T-Cell Activation with Spherical Nucleic Acids

Skakuj, K., Wang, S., Qin, L., Lee, A., Zhang, B. & Mirkin, C. A., Jan 31 2018, In : Journal of the American Chemical Society. 140, 4, p. 1227-1230 4 p.

Research output: Contribution to journalArticle

T-cells
Nucleic acids
Antigen-Presenting Cells
Antigens
Nucleic Acids
8 Citations (Scopus)

Smaller CpG-Conjugated Gold Nanoconstructs Achieve Higher Targeting Specificity of Immune Activation

Yue, J., Pallares, R. M., Cole, L. E., Coughlin, E. E., Mirkin, C. A., Lee, A. & Odom, T. W., Jul 5 2018, In : ACS Applied Materials and Interfaces. 10, 26, p. 21920-21926 7 p.

Research output: Contribution to journalArticle

Cytosine
Guanine
Gold
Phosphates
Chemical activation
2017
14 Citations (Scopus)

Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo

Sita, T. L., Kouri, F., Hurley, L. A., Merkel, T. J., Chalastanis, A., May, J. L., Ghelfi, S. T., Cole, L. E., Cayton, T. C., Barnaby, S. N., Sprangers, A. J., Savalia, N., James, C. D., Lee, A., Mirkin, C. A. & Stegh, A. H., Apr 18 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 16, p. 4129-4134 6 p.

Research output: Contribution to journalArticle

Nanoconjugates
Nucleic Acids
Fluorescence
Methyltransferases
Heterografts
25 Citations (Scopus)

Gold Nanoparticle Size and Shape Effects on Cellular Uptake and Intracellular Distribution of siRNA Nanoconstructs

Yue, J., Feliciano, T. J., Li, W., Lee, A. & Odom, T. W., Jun 21 2017, In : Bioconjugate Chemistry. 28, 6, p. 1791-1800 10 p.

Research output: Contribution to journalArticle

RNA
Gold
Nanoparticles
Small Interfering RNA
Endosomes
2014
40 Citations (Scopus)
Nanoparticles
Small Interfering RNA
Serum
Nucleic Acids
Hydrolysis