Grants per year
Personal profile
Research Interests
Children with atopic (allergic) diseases often worsen at night and suffer from sleep disturbances. The extent to which children with allergies have problems sleeping is not well known. Our research team is uncovering the reason eczema worsens at night. Ultimately we plan to develop new approaches in treating allergic disease, while focusing on outcomes important to our patients and their families. We welcome collaborators and families who are interested in participating in our research studies.
I am a pediatric physician scientist passionate about circadian immunology and its role in atopic inflammation. In my clinical practice, I saw a large need to improve the treatment of children who suffer from sleep disturbance related to atopic dermatitis (AD or eczema). In fact, we defined a new term to describe the phenomenon of nighttime atopic dermatitis exacerbation, nocturnal eczema. Given the importance of this topic clinically and mechanistically, my research focuses on 1) determining the circadian rhythms of inflammation and skin barrier in nocturnal eczema, 2) targeting the underlying mechanisms driving nocturnal disease flare in atopic dermatitis and 3) improving the assessment and treatment of sleep disturbance in atopic dermatitis. We have created an expert team in sleep, circadian rhythms, dermatology, and allergy & immunology at Northwestern University, including community members and national partners. Working with this team has been invigorating, and it is clear that we are uniquely capable of developing circadian-based therapeutics to personalize treatment for children with nocturnal eczema.
atopic dermatitis, sleep disturbance in atopy, hereditary angioedema, urticaria, food allergy, allergic rhinitis, asthma
Certifications and Licenses
Pediatrics | |
Allergy & Immunology |
Training Experience
2010 | Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
2012 | Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
Education/Academic qualification
MD, The University of Chicago
… → 2007
Medicine, MD, University of Chicago
… → 2007
Research interests
- Allergies
- Circadian Rhythms
- Dermatology
- Inflammation
- Pediatrics
- Skin
- Sleep Disorders
- Sleep and Sleep Disorders
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Network
Grants
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Circadian Rhythms of Skin Barrier, Pruritus and Inflammation in Atopic Dermatitis
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/25/19 → 8/31/24
Project: Research project
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PDE4A Expression as a Biomarker for Responsiveness to Eucrisa
7/16/19 → 8/31/50
Project: Research project
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Clinical management of Moderate-Severe Atopic Dermatitis in 0-2 year Olds by Community Based Pediatricians.
11/1/17 → 12/31/19
Project: Research project
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Improve Assessment of Sleep Disruption in Allergic Children
Northwestern University, Agency for Healthcare Research Quality
1/1/17 → 7/31/19
Project: Research project
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Improve Assessment of Sleep Disruption in Allergic Children
Northwestern University, Agency for Healthcare Research Quality
1/1/17 → 7/31/19
Project: Research project
Research Output
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Association between the longitudinal course of AD, sleep disturbance, and overall health in US children
McKenzie, C., Paller, A. S., Fishbein, A. & Silverberg, J. I., Feb 2020, In: Journal of Allergy and Clinical Immunology: In Practice. 8, 2, p. 812-814.e1Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Author response
Fishbein, A. B., Sheldon, S. & Grimaldi, D., Mar 15 2020, In: Journal of Clinical Sleep Medicine. 16, 3, p. 465 1 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Burden of emergency department utilization and abdominal imaging for hereditary angioedema
Cheng, B. T., Silverberg, J. I., Samet, J. D. & Fishbein, A. B., Apr 2020, In: Journal of Allergy and Clinical Immunology: In Practice. 8, 4, p. 1443-1446.e2Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Functional burden and limitations in children with chronic sinusitis
Cheng, B. T., Smith, S. S. & Fishbein, A. B., Jan 1 2020, In: Pediatric Allergy and Immunology. 31, 1, p. 103-105 3 p.Research output: Contribution to journal › Letter › peer-review
2 Scopus citations -
Management of Atopic Dermatitis in Children Younger Than Two Years of Age by Community Pediatricians: A Survey and Chart Review
Fishbein, A. B., Hamideh, N., Lor, J., Zhao, S., Kruse, L., Mason, M., Ariza, A., Bolanos, L., Necheles, J. & Kaye, B., Jun 2020, In: Journal of Pediatrics. 221, p. 138-144.e3Research output: Contribution to journal › Article › peer-review