Anna Fishbein

  • 851 Citations
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Personal profile

Research Interests

Children with atopic (allergic) diseases often worsen at night and suffer from sleep disturbances. The extent to which children with allergies have problems sleeping is not well known. Our research team is uncovering the reason eczema worsens at night. Ultimately we plan to develop new approaches in treating allergic disease, while focusing on outcomes important to our patients and their families. We welcome collaborators and families who are interested in participating in our research studies.

I am a pediatric physician scientist passionate about circadian immunology and its role in atopic inflammation. In my clinical practice, I saw a large need to improve the treatment of children who suffer from sleep disturbance related to atopic dermatitis (AD or eczema). In fact, we defined a new term to describe the phenomenon of nighttime atopic dermatitis exacerbation, nocturnal eczema. Given the importance of this topic clinically and mechanistically, my research focuses on 1) determining the circadian rhythms of inflammation and skin barrier in nocturnal eczema, 2) targeting the underlying mechanisms driving nocturnal disease flare in atopic dermatitis and 3) improving the assessment and treatment of sleep disturbance in atopic dermatitis. We have created an expert team in sleep, circadian rhythms, dermatology, and allergy & immunology at Northwestern University, including community members and national partners. Working with this team has been invigorating, and it is clear that we are uniquely capable of developing circadian-based therapeutics to personalize treatment for children with nocturnal eczema.

atopic dermatitis, sleep disturbance in atopy, hereditary angioedema, urticaria, food allergy, allergic rhinitis, asthma

Certifications and Licenses

Allergy & Immunology

Training Experience

2010Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital)
2012Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital)

Education/Academic qualification

MD, University of Chicago

… → 2007

Research interests

  • Allergies
  • Circadian Rhythms
  • Dermatology
  • Inflammation
  • Pediatrics
  • Skin
  • Sleep Disorders
  • Sleep and Sleep Disorders

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Grants 2015 2019

Research Output 2004 2020

Functional burden and limitations in children with chronic sinusitis

Cheng, B. T., Smith, S. S. & Fishbein, A. B., Jan 1 2020, In : Pediatric Allergy and Immunology. 31, 1, p. 103-105 3 p.

Research output: Contribution to journalLetter


Association between the longitudinal course of AD, sleep disturbance, and overall health in US children

McKenzie, C., Paller, A., Fishbein, A. & Silverberg, J. I., Jan 1 2019, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children

National Heart, Lung, and Blood Institute's AsthmaNet, May 2019, In : Journal of Allergy and Clinical Immunology. 143, 5, p. 1934-1937.e4

Research output: Contribution to journalArticle

Respiratory Sounds
Preschool Children
Adrenal Cortex Hormones

Neurocognitive function in moderate–severe pediatric atopic dermatitis: A case–control study

Kruse, L. L., Cices, A., Fishbein, A. & Paller, A., Jan 1 2019, In : Pediatric dermatology. 36, 1, p. 110-114 5 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Attention Deficit Disorder with Hyperactivity
Mental Disorders
Epidemiologic Studies

Sleep and limb movement characteristics of children with atopic dermatitis coincidentally undergoing clinical polysomnography

Treister, A. D., Stefek, H., Grimaldi, D., Rupani, N., Zee, P. C., Yob, J., Sheldon, S. H. & Fishbein, A., Aug 15 2019, In : Journal of Clinical Sleep Medicine. 15, 8, p. 1107-1113 7 p.

Research output: Contribution to journalReview article

Atopic Dermatitis
Nocturnal Myoclonus Syndrome