Anna P Lam

  • 993 Citations
20062021
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Personal profile

Research Interests

We are interested in understanding how the lung responds to injury and the process of normal healing, in order to develop novel therapies for treating patients with pulmonary fibrosis and similar types of lung disease.

Certifications and Licenses

Pulmonary Medicine
Critical Care Medicine

Training Experience

2003Residency, Northwestern University, McGaw Medical Center
2004Postdoctoral Fellowship, Northwestern University Feinberg School of Medicine
2007Fellowship, Northwestern University, McGaw Medical Center

Education/Academic qualification

MD, University of Maryland

… → 2000

Keywords

  • Cystic Fibrosis
  • Fibrosis
  • Interstitial Lung Disease
  • LAM (Lymphangioleiomyomatosis)

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  • 6 Similar Profiles
Catenins Medicine & Life Sciences
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Bleomycin Medicine & Life Sciences
Staphylococcal Pneumonia Medicine & Life Sciences

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Grants 2008 2021

Alveolar Epithelial Cells
Systemic Scleroderma
Interstitial Lung Diseases
Alveolar Macrophages
beta Catenin
Systemic Scleroderma
Interstitial Lung Diseases
beta Catenin
Catenins
Monocytes
Catenins
Pulmonary Fibrosis
beta Catenin
Innate Immunity
Idiopathic Pulmonary Fibrosis

Research Output 2006 2018

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C-I., Ren, Z., Verma, R., Abdala-Valencia, H., Nam, K., Chi, M., Han, S., Gonzalez-Gonzalez, F. J., Soberanes, S., Watanabe, S., Williams, K. J. N., Flozak, A. S. & 29 othersNicholson, T. T., Morgan, V. K., Winter, D. R., Hinchcliff, M., Hrusch, C. L., Guzy, R. D., Bonham, C. A., Sperling, A. I., Bag, R., Hamanaka, R. B., Mutlu, G. M., Yeldandi, A. V., Marshall, S. A., Shilatifard, A., Amaral, L. A. N., Perlman, H., Sznajder, J. I., Argento, A. C., Gillespie, C. T., Dematte, J., Jain, M., Singer, B. D., Ridge, K. M., Lam, A. P., Bharat, A., Bhorade, S. M., Gottardi, C. J., Budinger, G. R. S. & Misharin, A. V., Dec 15 2018, In : American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journalArticle

Single-Cell Analysis
Pulmonary Fibrosis
Lung
RNA Sequence Analysis
Alveolar Macrophages
12 Citations (Scopus)
Low Density Lipoprotein Receptor-Related Protein-5
Catenins
Macrophages
Fibrosis
Lung
85 Citations (Scopus)

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

Misharin, A. V., Morales-Nebreda, L., Reyfman, P. A., Cuda, C. M., Walter, J. M., McQuattie-Pimentel, A. C., Chen, C. I., Anekalla, K. R., Joshi, N., Williams, K. J. N., Abdala-Valencia, H., Yacoub, T. J., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Gates, K., Lam, A. P., Nicholson, T. T., Homan, P. J., Soberanes, S. & 23 othersDominguez, S., Morgan, V. K., Saber, R., Shaffer, A., Hinchcliff, M., Marshall, S. A., Bharat, A., Berdnikovs, S., Bhorade, S. M., Bartom, E. T., Morimoto, R. I., Balch, W. E., Sznajder, J. I., Chandel, N. S., Mutlu, G. M., Jain, M., Gottardi, C. J., Singer, B. D., Ridge, K. M., Bagheri, N., Shilatifard, A., Budinger, G. R. S. & Perlman, H., Aug 1 2017, In : Journal of Experimental Medicine. 214, 8, p. 2387-2404 18 p.

Research output: Contribution to journalArticle

Alveolar Macrophages
Fibrosis
Macrophages
Lung
Monocytes
7 Citations (Scopus)

Adiponectin inhibits Wnt co-receptor, Lrp6, phosphorylation and β-catenin signaling

Reinke, L., Lam, A. P., Flozak, A. S., Varga, J. & Gottardi, C., Feb 12 2016, In : Biochemical and Biophysical Research Communications. 470, 3, p. 606-612 7 p.

Research output: Contribution to journalArticle

Wnt Receptors
Catenins
Phosphorylation
Adiponectin
Chemical activation

A simple method to assess abundance of the β-Catenin signaling pool in cells

Flozak, A. S., Lam, A. P. & Gottardi, C. J., Jan 1 2016, Methods in Molecular Biology. Humana Press Inc, p. 49-60 12 p. (Methods in Molecular Biology; vol. 1481).

Research output: Chapter in Book/Report/Conference proceedingChapter

Catenins
Cadherins
Transducers