Grants per year
Personal profile
Research Interests
I have played a prominent role in the field of urologic research, publishing extensively on urinary tract infection (UTI), inflammation and incontinence. Among my major contributions are several clinical techniques for both male and female incontinence, including an innovative urethral sling procedure. Along with colleagues, I was the first to describe the systemic changes of bacteria binding that subsequently cause UTIs in women and developed a novel technique for patient-based management of them. I have published more than 400 peer-reviewed articles and is currently a member of the NIH Multi-Site Collaborative Research Project on male chronic pelvic pain syndrome (prostatitis). I have maintained continuous NIH funding since 1978 and contributes regularly to international panels to establish guidelines for management of UTIs.
My clinical and research interests involve urinary tract infections, prostatitis, and chronic pelvic pain syndrome.
Certifications and Licenses
| Urology |
Training Experience
| 1969 | Internship, Northwestern University, McGaw Medical Center |
| 1970 | Residency, Northwestern University, McGaw Medical Center |
| 1976 | Residency, Stanford University Hospitals |
Education/Academic qualification
Medicine, MD, Northwestern University
… → 1968
Research interests keywords
- Bacterial Pathogenesis
- Cytokines
- Urology
Fingerprint
Dive into the research topics where Anthony J Schaeffer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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TLR Transduction of Dysbiotic Pelvic Pain
Klumpp, D. (PD/PI), Schaeffer, A. J. (Co-Investigator) & Winter, D. R. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
8/21/23 → 6/30/27
Project: Research project
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Lipoteichoic acid mediated modulation of chronic pain
Thumbikat, P. (PD/PI), Thumbikat, P. (PD/PI), Martina, M. (Co-Investigator), Martina, M. (Co-Investigator), Schaeffer, A. J. (Co-Investigator), Schaeffer, A. J. (Co-Investigator), Liu, Z. (Other) & Liu, Z. (Other)
National Institute of Diabetes and Digestive and Kidney Diseases
9/1/22 → 6/30/26
Project: Research project
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Randomized Trial Comparing MRI-Targeted Transperineal vs. Transrectal Prostate Biopsy
Schaeffer, E. M. (PD/PI), Kundu, S. D. (Co-Investigator), Schaeffer, A. J. (Co-Investigator) & Ross, A. E. (Other)
Joan and Sanford I. Weill Medical College of Cornell University, Patient-Centered Outcomes Research Institute
4/1/21 → 3/31/24
Project: Research project
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Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome
Thumbikat, P. (PD/PI), Cao, Q. (Co-Investigator), Flury, S. C. (Co-Investigator) & Schaeffer, A. J. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
9/15/20 → 7/31/24
Project: Research project
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Evaluation of Transperineal Biopsy under Local Anesthesia, a Novel approach to Decrease Post-Biopsy Infections and Improve Cancer Detection
Schaeffer, E. M. (PD/PI), Schaeffer, E. M. (PD/PI), Schaeffer, A. J. (Co-Investigator) & Schaeffer, A. J. (Co-Investigator)
Joan and Sanford I. Weill Medical College of Cornell University, National Cancer Institute
9/11/20 → 6/30/24
Project: Research project
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Efficacy of Targeted Mast Cell Inhibition Therapy in Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Pattabiraman, G., Engel, G., Osborn, C. V., Murphy, S. F., Schaeffer, A. J. & Thumbikat, P., Oct 2023, In: Urology. 180, p. 200-208 9 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Protocol of a multicentre randomised controlled trial assessing transperineal prostate biopsy to reduce infectiouscomplications
Hu, J., Zhu, A., Vickers, A., Allaf, M. E., Ehdaie, B., Schaeffer, A., Pavlovich, C., Ross, A. E., Green, D. A., Wang, G., Ginzburg, S., Montgomery, J. S., George, A., Graham, J. N., Ristau, B. T., Correa, A., Shoag, J. E., Kowalczyk, K. J., Zhang, T. R. & Schaeffer, E. M., May 19 2023, In: BMJ open. 13, 5, e071191.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Acyloxyacyl hydrolase regulates microgliamediated pelvic pain
Rahman-Enyart, A., Yaggie, R. E., Bollinger, J. L., Arvanitis, C., Winter, D. R., Schaeffer, A. J. & Klumpp, D. J., Aug 2022, In: PloS one. 17, 8 August, e0269140.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Acyloxyacyl hydrolase is a host determinant of gut microbiome-mediated pelvic pain
Rahman-Enyart, A., Yang, W., Yaggie, R. E., White, B. A., Welge, M., Auvil, L., Berry, M., Bushell, C., Rosen, J. M., Rudick, C. N., Schaeffer, A. J. & Klumpp, D. J., Aug 25 2021, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 321, 3, p. R396-R412Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Mast cell function in prostate inflammation, fibrosis, and smooth muscle cell dysfunction
Pattabiraman, G., Bell-Cohn, A. J., Murphy, S. F., Mazur, D. J., Schaeffer, A. J. & Thumbikat, P., Sep 2021, In: American Journal of Physiology - Renal Physiology. 321, 4, p. F466-F479Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations
Datasets
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Evaluation of targeted antimicrobial prophylaxis for transrectal ultrasound guided prostate biopsy: a prospective cohort trial
Zembower, T. R. (Creator), Maxwell, K. M. (Creator), Nadler, R. B. (Creator), Cashy, J. (Creator), Scheetz, M. H. (Creator), Qi, C. (Creator) & Schaeffer, A. J. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3798214.v1, https://figshare.com/collections/Evaluation_of_targeted_antimicrobial_prophylaxis_for_transrectal_ultrasound_guided_prostate_biopsy_a_prospective_cohort_trial/3798214/1
Dataset