Grants per year
Personal profile
Research Interests
I have played a prominent role in the field of urologic research, publishing extensively on urinary tract infection (UTI), inflammation and incontinence. Among my major contributions are several clinical techniques for both male and female incontinence, including an innovative urethral sling procedure. Along with colleagues, I was the first to describe the systemic changes of bacteria binding that subsequently cause UTIs in women and developed a novel technique for patient-based management of them. I have published more than 400 peer-reviewed articles and is currently a member of the NIH Multi-Site Collaborative Research Project on male chronic pelvic pain syndrome (prostatitis). I have maintained continuous NIH funding since 1978 and contributes regularly to international panels to establish guidelines for management of UTIs.
My clinical and research interests involve urinary tract infections, prostatitis, and chronic pelvic pain syndrome.
Certifications and Licenses
Urology |
Training Experience
1969 | Internship, Northwestern University, McGaw Medical Center |
1970 | Residency, Northwestern University, McGaw Medical Center |
1976 | Residency, Stanford University Hospitals |
Education/Academic qualification
MD, Northwestern University, Feinberg School of Medicine
… → 1968
Research interests
- Bacterial Pathogenesis
- Cytokines
- Urology
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Grants
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Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome
Flury, S. C., Schaeffer, A. J., Thumbikat, P. & Cao, Q.
National Institute of Diabetes and Digestive and Kidney Diseases
9/15/20 → 7/31/23
Project: Research project
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Pelvic Pain and Depression
Flury, S. C., Griffith, J. W., Klumpp, D., Miller, R. J., Parrish, T. B. & Schaeffer, A. J.
National Institute of Diabetes and Digestive and Kidney Diseases
7/1/19 → 8/13/22
Project: Research project
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Lipoteichoic acid mediated immune modulation of chronic pain
Murphy, S. F., Schaeffer, A. J., Thaxton, C. S. & Thumbikat, P.
National Institute of Diabetes and Digestive and Kidney Diseases
8/1/16 → 7/31/21
Project: Research project
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Mast cells in male pelvic pain and lower urinary tract dysfunction
Hairston, J. C., McKenna, K. E., Schaeffer, A. J. & Thumbikat, P.
National Institute of Diabetes and Digestive and Kidney Diseases
7/1/16 → 6/30/21
Project: Research project
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Altered Microbiome of Chronic Pelvic Pain
Andersen, E. C., Griffith, J. W., Klumpp, D., Radulovic, J. & Schaeffer, A. J.
National Institute of Diabetes and Digestive and Kidney Diseases
5/18/16 → 2/28/21
Project: Research project
Research Output
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Acyloxyacyl hydrolase regulates voiding activity
Aguiniga, L. M., Searl, T. J., Rahman-Enyart, A., Yaggie, R. E., Yang, W., Schaeffer, A. J. & Klumpp, D. J., Apr 2020, In: American Journal of Physiology - Renal Physiology. 318, 4, p. F1006-F1016Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Algorithms to Enhance Empiric Antimicrobial Choice for Outpatients With Afebrile Complicated Cystitis Reflects Importance of Status of the Urinary Tract and Patient Place of Residence
Cooley, L. F., Cohen, J. E., Chen, L. & Schaeffer, A. J., Nov 2020, In: Urology. 145, p. 127-133 7 p.Research output: Contribution to journal › Article › peer-review
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Algorithms Using Previous Resistance, Prior Antimicrobial Prescriptions, and Patient Place of Residence Enhance Empirical Therapy for Women With Uncomplicated Urinary Tract Infections
Cohen, J. E., Chen, L. & Schaeffer, A. J., Mar 2020, In: Urology. 137, p. 72-78 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A novel immunocompetent model of metastatic prostate cancer-induced bone pain
Liu, Z., Murphy, S. F., Huang, J., Zhao, L., Hall, C. C., Schaeffer, A. J., Schaeffer, E. M. & Thumbikat, P., Jul 1 2020, In: Prostate. 80, 10, p. 782-794 13 p.Research output: Contribution to journal › Article › peer-review
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AOAH remodels arachidonic acid-containing phospholipid pools in a model of interstitial cystitis pain: A MAPP Network study
Yang, W., Yaggie, R. E., Schaeffer, A. J. & Klumpp, D. J., Sep 2020, In: PloS one. 15, 9 September, e0235384.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations