Grants per year
Personal profile
Research Interests
I have played a prominent role in the field of urologic research, publishing extensively on urinary tract infection (UTI), inflammation and incontinence. Among my major contributions are several clinical techniques for both male and female incontinence, including an innovative urethral sling procedure. Along with colleagues, I was the first to describe the systemic changes of bacteria binding that subsequently cause UTIs in women and developed a novel technique for patient-based management of them. I have published more than 400 peer-reviewed articles and is currently a member of the NIH Multi-Site Collaborative Research Project on male chronic pelvic pain syndrome (prostatitis). I have maintained continuous NIH funding since 1978 and contributes regularly to international panels to establish guidelines for management of UTIs.
My clinical and research interests involve urinary tract infections, prostatitis, and chronic pelvic pain syndrome.
Certifications and Licenses
| Urology |
Training Experience
| 1969 | Internship, Northwestern University, McGaw Medical Center |
| 1970 | Residency, Northwestern University, McGaw Medical Center |
| 1976 | Residency, Stanford University Hospitals |
Education/Academic qualification
MD, Northwestern University Feinberg School of Medicine
… → 1968
Research interests
- Bacterial Pathogenesis
- Cytokines
- Urology
Fingerprint Dive into the research topics where Anthony J Schaeffer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 16 Similar Profiles
Prostatitis
Medicine & Life Sciences
Urinary Tract Infections
Medicine & Life Sciences
Pelvic Pain
Medicine & Life Sciences
Chronic Pain
Medicine & Life Sciences
Urinary Bladder
Medicine & Life Sciences
Bacteriuria
Medicine & Life Sciences
Escherichia coli
Medicine & Life Sciences
Uropathogenic Escherichia coli
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2001 2022
Pelvic Pain and Depression
Flury, S. C., Griffith, J. W., Klumpp, D., Miller, R. J., Parrish, T. B. & Schaeffer, A. J.
National Institute of Diabetes, Digestive and Kidney Diseases
7/1/19 → 8/13/22
Project: Research project
Pelvic Pain
Depression
Chronic Pain
Neuroimaging
Comorbidity
Lipoteichoic acid mediated immune modulation of chronic pain
Murphy, S. F., Schaeffer, A. J., Thaxton, C. S. & Thumbikat, P.
National Institute of Diabetes, Digestive and Kidney Diseases
8/1/16 → 7/31/20
Project: Research project
Pelvic Pain
Chronic Pain
Prostatitis
Prostate
Cell Degranulation
Mast cells in male pelvic pain and lower urinary tract dysfunction
Hairston, J. C., McKenna, K. E., Schaeffer, A. J. & Thumbikat, P.
National Institute of Diabetes, Digestive and Kidney Diseases
7/1/16 → 6/30/21
Project: Research project
PAR-2 Receptor
Tryptases
Prostatitis
Pelvic Pain
Urinary Tract
Altered Microbiome of Chronic Pelvic Pain
Andersen, E. C., Griffith, J. W., Klumpp, D., Radulovic, J. & Schaeffer, A. J.
National Institute of Diabetes, Digestive and Kidney Diseases
5/18/16 → 2/29/20
Project: Research project
Pelvic Pain
Microbiota
Chronic Pain
Probiotics
Gastrointestinal Tract
Mechanisms of Probiotic Analgesia
Klumpp, D., Miller, R. J. & Schaeffer, A. J.
National Center for Complementary and Integrative Health
9/1/14 → 6/30/20
Project: Research project
Research Output 1974 2019
Acyloxyacyl hydrolase modulates depressive-like behaviors through aryl hydrocarbon receptor
MAPP Research Network Study Group, Aug 1 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 317, 2, p. R289-R300Research output: Contribution to journal › Article
Aryl Hydrocarbon Receptors
Peroxisome Proliferator-Activated Receptors
Paraventricular Hypothalamic Nucleus
Corticotropin-Releasing Hormone
Arachidonic Acid
6
Citations
(Scopus)
Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America
Nicolle, L. E., Gupta, K., Bradley, S. F., Colgan, R., DeMuri, G. P., Drekonja, D., Eckert, L. O., Geerlings, S. E., Köves, B., Hooton, T. M., Juthani-Mehta, M., Knight, S. L., Saint, S., Schaeffer, A. J., Trautner, B., Wullt, B. & Siemieniuk, R., May 1 2019, In : Clinical Infectious Diseases. 68, 10, p. E83-E75Research output: Contribution to journal › Review article
Bacteriuria
Practice Management
Practice Guidelines
Guidelines
Population
3
Citations
(Scopus)
Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America
Nicolle, L. E., Gupta, K., Bradley, S. F., Colgan, R., DeMuri, G. P., Drekonja, D., Eckert, L. O., Geerlings, S. E., Köves, B., Hooton, T. M., Juthani-Mehta, M., Knight, S. L., Saint, S., Schaeffer, A. J., Trautner, B., Wullt, B. & Siemieniuk, R., May 1 2019, In : Clinical Infectious Diseases. 68, 10, p. 1611-1615 5 p.Research output: Contribution to journal › Review article
Open Access
Bacteriuria
Practice Management
Practice Guidelines
Guidelines
Population
2
Citations
(Scopus)
Role of gram-positive bacteria in chronic pelvic pain syndrome (CPPS)
Murphy, S. F., Anker, J. F., Mazur, D. J., Hall, C., Schaeffer, A. J. & Thumbikat, P., Feb 1 2019, In : Prostate. 79, 2, p. 160-167 8 p.Research output: Contribution to journal › Article
Pelvic Pain
Gram-Positive Bacteria
Chronic Pain
Hyperalgesia
Prostate
2
Citations
(Scopus)
Uropathogenic escherichia coli-induced fibrosis, leading to lower urinary tract symptoms, is associated with type 2 cytokine signaling
Bell-Cohn, A., Mazur, D. J., Hall, C., Schaeffer, A. J. & Thumbikat, P., Apr 1 2019, In : American Journal of Physiology - Renal Physiology. 316, 4, p. F682-F692Research output: Contribution to journal › Article
Uropathogenic Escherichia coli
Lower Urinary Tract Symptoms
Fibrosis
Prostate
Cytokines