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Aparna Kalyan

  • 387 Citations
20142021
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Personal profile

Research Interests

My primary interests are in developing novel therapeutic combinations for the treatment of gastrointestinal cancers. I am interested in incorporating immunotherapy and molecular testing into clinical trials.

Training Experience

2009Residency, St. Vincents Hospital, Melbourne Australia
2011Residency, University Hospitals Case Medical Center, Cleveland OH
2014Fellowship, University of Pittsburgh Medical Center
2014Fellowship, Northwestern University

Education/Academic qualification

MBBS, Flinders University of South Australia, Australia

… → 2005

Keywords

  • Cancer Biology
  • Nanotechnology
  • Pancreatic Cancer
  • Colon / Rectal Cancer

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 15 Similar Profiles
Neoplasms Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Biliary Tract Neoplasms Medicine & Life Sciences
Colorectal Neoplasms Medicine & Life Sciences
Fibroblast Growth Factor Receptors Medicine & Life Sciences
gemcitabine Medicine & Life Sciences
Hepatocellular Carcinoma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2015 2021

Prot #H3B-6527-G000-101: An Open-Label Multicenter Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Subjects With Advanced Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma

Kalyan, A.

PPD Investigator Services, LLC, H3 Biomedicine Inc.

2/14/18 → 2/14/21

Project: Research project

Prot #AG120-C-005: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-controlled Study of AG-120 in Previously-treated Subjects with Nonresectable or Metastatic Cholangiocarcinoma with an IDH1 Mutation

Kalyan, A.

DrugDev Inc., Agios Pharmaceuticals, Inc.

1/25/18 → 1/25/21

Project: Research project

Prot #NC-6004-004A: A Phase 1b/2 Dose Escalation and Expansion Trial of NC-6004 (Nanoparticle Cisplatin) plus Gemcitabine in Patients with Advanced Solid Tumors or Squamous Non-Small Cell Lung, Biliary Tract, and Bladder Cancer

Kalyan, A.

PPD Investigator Services, LLC, NanoCarrier Co., Ltd.

8/29/17 → 8/29/20

Project: Research project

Prot #ABI-007-PANC-009: An Open-Label, Multicenter, Single-Arm, Phase 1/2 Study Of Metronomic 5-Fluorouracil In Combination With Nabpaclitaxel, Bevacizumab, Leucovorin, And Oxaliplatin In Patients With Metastatic Pancreatic Adenocarcinoma

Kalyan, A.

INC Research, LLC, Celgene Corporation

8/10/16 → 8/10/19

Project: Research project

Prot #ABI-007-ST-001: A Phase 1, Open-Label, Multicenter, Safety Study of Nivolumab (BMS-936558) in Combination with nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or

Kalyan, A.

PPD Development, Celgene Corporation

11/11/15 → 11/11/18

Project: Research project

Research Output 2014 2019

  • 387 Citations
  • 14 Article
  • 7 Review article
  • 3 Comment/debate
  • 1 Editorial

A Case of Metastatic Biliary Tract Cancer Diagnosed Through Identification of an IDH1 Mutation

Kamath, S. D., Lin, X. & Kalyan, A., Feb 1 2019, In : Oncologist. 24, 2, p. 151-156 6 p.

Research output: Contribution to journal › Article

Biliary Tract Neoplasms
Mutation
Adenocarcinoma
Neoplasms
Paraffin

Piloting a Financial Counseling Intervention for Patients With Cancer Receiving Chemotherapy

Kircher, S. M., Yarber, J., Rutsohn, J., Guevara, Y., Lyleroehr, M., Alphs Jackson, H., Walradt, J., Desai, B., Mulcahy, M. F., Kalyan, A., Benson, A. B., Agulnik, M., Mohindra, N. A., DeSouza, J. & Garcia, S. F., Mar 1 2019, In : Journal of oncology practice. 15, 3, p. e202-e210

Research output: Contribution to journal › Article

Counseling
Drug Therapy
Neoplasms
Costs and Cost Analysis
Workflow
1 Citation (Scopus)

Pembrolizumab for the treatment of gastric cancer

Kamath, S. D., Kalyan, A. & Benson III, A. B., Dec 2 2018, In : Expert Review of Anticancer Therapy. 18, 12, p. 1177-1187 11 p.

Research output: Contribution to journal › Article

Stomach Neoplasms
Immunotherapy
Stomach
Dysbiosis
Therapeutics
8 Citations (Scopus)

Updates on immunotherapy for colorectal cancer

Kalyan, A., Kircher, S., Shah, H., Mulcahy, M. & Benson, A., Feb 1 2018, In : Journal of Gastrointestinal Oncology. 9, 1, p. 160-169 10 p.

Research output: Contribution to journal › Review article

Immunotherapy
Colorectal Neoplasms
Active Immunotherapy
Standard of Care
Microsatellite Repeats
9 Citations (Scopus)

A comprehensive review of heregulins, HER3, and HER4 as potential therapeutic targets in cancer

Mota, J. M., Collier, K. A., Costa, R. L. B., Taxter, T., Kalyan, A., Leite, C. A., Chae, Y. K., Giles, F. J. & Carneiro, B. A., Jan 1 2017, In : Oncotarget. 8, 51, p. 89284-89306 23 p.

Research output: Contribution to journal › Article

Neuregulin-1
Neoplasms
Therapeutics
Breast Neoplasms
Dimerization