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Aparna Kalyan

  • 670 Citations
20142020

Research output per year

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Personal profile

Research Interests

My primary interests are in developing novel therapeutic combinations for the treatment of gastrointestinal cancers. I am interested in incorporating immunotherapy and molecular testing into clinical trials.

Training Experience

2009Residency, St. Vincents Hospital, Melbourne Australia
2011Residency, University Hospitals Case Medical Center, Cleveland OH
2014Fellowship, University of Pittsburgh Medical Center
2014Fellowship, Northwestern University

Education/Academic qualification

MBBS, Flinders University

… → 2005

Research interests

  • Cancer Biology
  • Colon / Rectal Cancer
  • Nanotechnology
  • Pancreatic Cancer

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Grants

Prot #H3B-6527-G000-101: An Open-Label Multicenter Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Subjects With Advanced Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma

Kalyan, A.

PPD Investigator Services, LLC, H3 Biomedicine Inc.

2/14/18 → 2/14/21

Project: Research project

Prot #AG120-C-005: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-controlled Study of AG-120 in Previously-treated Subjects with Nonresectable or Metastatic Cholangiocarcinoma with an IDH1 Mutation

Kalyan, A.

DrugDev Inc., Agios Pharmaceuticals, Inc.

1/25/18 → 1/25/21

Project: Research project

Prot #NC-6004-004A: A Phase 1b/2 Dose Escalation and Expansion Trial of NC-6004 (Nanoparticle Cisplatin) plus Gemcitabine in Patients with Advanced Solid Tumors or Squamous Non-Small Cell Lung, Biliary Tract, and Bladder Cancer

Kalyan, A.

PPD Investigator Services, LLC, NanoCarrier Co., Ltd.

8/29/17 → 8/29/20

Project: Research project

Prot #D419NC00001: A Phase 1 Study of Durvalumab and IPH2201 in Adult Subjects with Select Advanced Solid Tumors

Carneiro Filho, B. A., Chae, Y. K. & Kalyan, A.

MedImmune, LLC

2/6/17 → 2/6/23

Project: Research project

Prot #ABI-007-PANC-009: An Open-Label, Multicenter, Single-Arm, Phase 1/2 Study Of Metronomic 5-Fluorouracil In Combination With Nabpaclitaxel, Bevacizumab, Leucovorin, And Oxaliplatin In Patients With Metastatic Pancreatic Adenocarcinoma

Kalyan, A.

INC Research, LLC, Celgene Corporation

8/10/16 → 8/10/19

Project: Research project

Research Output

  • 670 Citations
  • 20 Article
  • 6 Review article
  • 3 Comment/debate
  • 1 Editorial

Ipilimumab and Gemcitabine for Advanced Pancreatic Cancer: A Phase Ib Study

Kamath, S. D., Kalyan, A., Kircher, S., Nimeiri, H. S., Fought, A. J., Benson, A. & Mulcahy, M., May 1 2020, In : Oncologist. 25, 5, p. e808-e815

Research output: Contribution to journal › Article

    • 2 Scopus citations

    Streamlining radioembolization in UNOS T1/T2 hepatocellular carcinoma by eliminating lung shunt estimation

    Gabr, A., Ranganathan, S., Mouli, S. K., Riaz, A., Gates, V. L., Kulik, L., Ganger, D., Maddur, H., Moore, C., Hohlastos, E., Katariya, N., Caicedo, J. C., Kalyan, A., Lewandowski, R. J. & Salem, R., Jun 2020, In : Journal of Hepatology. 72, 6, p. 1151-1158 8 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    A Case of Metastatic Biliary Tract Cancer Diagnosed Through Identification of an IDH1 Mutation

    Kamath, S. D., Lin, X. & Kalyan, A., Feb 2019, In : Oncologist. 24, 2, p. 151-156 6 p.

    Research output: Contribution to journal › Article

    • First-in-Human Phase I Study of Aprutumab Ixadotin, a Fibroblast Growth Factor Receptor 2 Antibody–Drug Conjugate (BAY 1187982) in Patients with Advanced Cancer

    Kim, S. B., Meric-Bernstam, F., Kalyan, A., Babich, A., Liu, R., Tanigawa, T., Sommer, A., Osada, M., Reetz, F., Laurent, D., Wittemer-Rump, S. & Berlin, J., Oct 1 2019, In : Targeted Oncology. 14, 5, p. 591-601 11 p.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Scopus citations

    Piloting a financial counseling intervention for patients with cancer receiving chemotherapy

    Kircher, S. M., Yarber, J., Rutsohn, J., Guevara, Y., Lyleroehr, M., Jackson, H. A., Walradt, J., Desai, B., Mulcahy, M., Kalyan, A., Benson, A. B., Agulnik, M., Mohindra, N., DeSouza, J. & Garcia, S. F., Mar 1 2019, In : Journal of oncology practice. 15, 3, p. E202-E210

    Research output: Contribution to journal › Article

    • 2 Scopus citations