Grants per year
Personal profile
Research Interests
The focus of my laboratory research is to elucidate the mechanisms of therapeutic resistance in brain tumor. We are particularly interested in investigating the role of cellular plasticity in promoting the cancer stem cell niche and disease recurrence.
Training Experience
| 2009 | Postdoctoral Fellowship, Mayo Medical School |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Mayo Medical School
… → 2007
Research interests keywords
- Bioengineering
- Brain Cancer / Nervous System Cancer
- Cancer Biology
- Cancer Genetics
- Cell Biology
- Cell Imaging
- Chemotherapy
- Gene Therapy
- Stem Cells
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Project 4
Ahmed, A. U., Ganger, D. R., Kumthekar, P. U., Miska, J. M. & Stupp, R.
8/1/23 → 7/31/28
Project: Research project
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The hypoxic niche in glioblastoma is maintained by myeloid produced creatine
Miska, J. M., Miska, J. M., Ahmed, A. U., Ahmed, A. U., Brat, D. J., Brat, D. J., Lee Chang, C. & Lee Chang, C.
4/1/23 → 3/31/28
Project: Research project
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Cellular Plasticity and equilibrium in GBM Progression
Ahmed, A. U., Ahmed, A. U., Ben-Sahra, I., Ben-Sahra, I., James, C. D., James, C. D., Miska, J. M., Miska, J. M., Zhang, H. & Zhang, H.
National Institute of Neurological Disorders and Stroke
7/15/22 → 5/31/27
Project: Research project
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Role of purine metabolism in chemoresistance
Ahmed, A. U., Ahmed, A. U., Ben-Sahra, I., Ben-Sahra, I., Horbinski, C. M. & Horbinski, C. M.
National Institute of Neurological Disorders and Stroke
9/1/19 → 6/30/24
Project: Research project
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Elucidating the Role of R-loops as Modulators of Glioblastoma Aggression
American Brain Tumor Association
6/1/22 → 8/31/22
Project: Research project
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Docetaxel targets aggressive methylation profiles and serves as a radiosensitizer in high-risk meningiomas
Youngblood, M. W., Tran, A. N., Wang, W., An, S., Scholtens, D., Zhang, L., O'Shea, K., Pokorny, J. L., Magill, S. T., Sachdev, S., Lukas, R. V., Ahmed, A., Unruh, D., Walshon, J., McCortney, K., Wang, Y., Baran, A., Sahm, F., Aldape, K., Chandler, J. P., & 3 others, Mar 14 2023, In: Neuro-oncology. 25, 3, p. 508-519 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Endoplasmic Reticulum Stress in the Brain Tumor Immune Microenvironment
Petrosyan, E., Fares, J., Fernandez, L. G., Yeeravalli, R., Dmello, C., Duffy, J. T., Zhang, P., Lee-Chang, C., Miska, J., Ahmed, A. U., Sonabend, A. M., Balyasnikova, I. V., Heimberger, A. B. & Lesniak, M. S., May 1 2023, In: Molecular Cancer Research. 21, 5, p. 389-396 8 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production
Perrault, E. N., Shireman, J. M., Ali, E. S., Lin, P., Preddy, I., Park, C., Budhiraja, S., Baisiwala, S., Dixit, K., James, C. D., Heiland, D. H., Ben-Sahra, I., Pott, S., Basu, A., Miska, J. & Ahmed, A. U., 2023, In: Science Advances. 9, 20, eade7236.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Checkpoint: Inspecting the barriers in glioblastoma immunotherapies
Preddy, I., Nandoliya, K., Miska, J. & Ahmed, A. U., Nov 2022, In: Seminars in Cancer Biology. 86, p. 473-481 9 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma
Xuan, W., Hsu, W. H., Khan, F., Dunterman, M., Pang, L., Wainwright, D. A., Ahmed, A. U., Heimberger, A. B., Lesniak, M. S. & Chen, P., Jun 2022, In: Cancer Immunology Research. 10, 6, p. 770-784 15 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations
Datasets
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Single dose GLP toxicity and biodistribution study of a conditionally replicative adenovirus vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters
Kim, J. W. (Creator), Auffinger, B. (Creator), Spencer, D. A. (Creator), Miska, J. M. (Creator), Chang, A. L. (Creator), Kane, J. R. (Creator), Young, J. S. (Creator), Kanojia, D. (Creator), Qiao, J. (Creator), Mann, J. F. (Creator), Zhang, L. (Contributor), Wu, M. (Contributor), Ahmed, A. U. (Contributor), Aboody, K. S. (Creator), Strong, T. V. (Creator), Hébert, C. D. (Creator), Lesniak, M. S. (Creator) & Meijing, W. (Contributor), figshare, 2016
DOI: 10.6084/m9.figshare.c.3624035.v1, https://figshare.com/collections/Single_dose_GLP_toxicity_and_biodistribution_study_of_a_conditionally_replicative_adenovirus_vector_CRAd-S-pk7_administered_by_intracerebral_injection_to_Syrian_hamsters/3624035/1
Dataset