Grants per year
Personal profile
Research Interests
The focus of my laboratory research is to elucidate the mechanisms of therapeutic resistance in brain tumor. We are particularly interested in investigating the role of cellular plasticity in promoting the cancer stem cell niche and disease recurrence.
Training Experience
| 2009 | Postdoctoral Fellowship, Mayo Medical School |
Education/Academic qualification
PhD, Mayo Medical School
… → 2007
Research interests
- Bioengineering
- Brain Cancer / Nervous System Cancer
- Cancer Biology
- Cancer Genetics
- Cell Biology
- Cell Imaging
- Chemotherapy
- Gene Therapy
- Stem Cells
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Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants
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Role of purine metabolism in chemoresistance
Ahmed, A. U., Ben-Sahra, I. & Horbinski, C. M.
National Institute of Neurological Disorders and Stroke
9/1/19 → 6/30/24
Project: Research project
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SPORE for Translational Approaches to Brain Cancer
Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Chandler, J. P., Cheng, S., Horbinski, C. M., Hu, B., James, C. D., Kumthekar, P. U., Leikin, R. G., Lesniak, M. S., Liu, B. P., Lukas, R. V., Platanias, L. C., Sachdev, S., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.
8/17/18 → 7/31/23
Project: Research project
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Cellular plasticity and equilibrium in GBM progression
Ahmed, A. U., Horbinski, C. M., James, C. D. & Shilatifard, A.
National Institute of Neurological Disorders and Stroke
4/1/17 → 1/31/22
Project: Research project
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Therapeutic Targeting of Malignant Glioma Stem Cells
Ahmed, A. U., Lesniak, M. S. & Yu, D.
11/1/15 → 7/31/22
Project: Research project
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THE ROLE OF LNX1 IN GLIOMA STEM CELL EXPANSION
Neurosurgery Research and Education Foundation
4/25/18 → 10/25/18
Project: Research project
Research Output
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BET inhibition increases βIII-tubulin expression and sensitizes metastatic breast cancer in the brain to vinorelbine
Kanojia, D., Panek, W. K., Cordero, A., Fares, J., Xiao, A., Savchuk, S., Kumar, K., Xiao, T., Pituch, K. C., Miska, J., Zhang, P., Kam, K. L., Horbinski, C., Balyasnikova, I. V., Ahmed, A. U. & Lesniak, M. S., Aug 2020, In: Science translational medicine. 12, 558, eaax2879.Research output: Contribution to journal › Article › peer-review
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LNX1 modulates Notch1 signaling to promote expansion of the glioma stem cell population during temozolomide therapy in glioblastoma
Baisiwala, S., Hall, R. R., Saathoff, M. R., Shireman, J. M., Park, C., Budhiraja, S., Goel, C., Warnke, L., Hardiman, C., Wang, J. Y., McCortney, K., Horbinski, C. M. & Ahmed, A. U., Dec 2020, In: Cancers. 12, 12, p. 1-19 19 p., 3505.Research output: Contribution to journal › Article › peer-review
Open Access -
Ribosomal protein S11 influences glioma response to TOP2 poisons
Awah, C. U., Chen, L., Bansal, M., Mahajan, A., Winter, J., Lad, M., Warnke, L., Gonzalez-Buendia, E., Park, C., Zhang, D., Feldstein, E., Yu, D., Zannikou, M., Balyasnikova, I. V., Martuscello, R., Konerman, S., Győrffy, B., Burdett, K. B., Scholtens, D. M., Stupp, R. & 3 others, , Jul 2 2020, In: Oncogene. 39, 27, p. 5068-5081 14 p.Research output: Contribution to journal › Article › peer-review
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Separate and not equal: sex differences in JAM-A tumor suppression in glioblastoma
Shireman, J. M. & Ahmed, A. U., Nov 26 2020, In: Neuro-oncology. 22, 11, p. 1555-1556 2 p.Research output: Contribution to journal › Article › peer-review
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Temozolomide treatment increases fatty acid uptake in glioblastoma stem cells
Caragher, S., Miska, J. M., Shireman, J., Park, C. H., Muroski, M., Lesniak, M. S. & Ahmed, A. U., Nov 2020, In: Cancers. 12, 11, p. 1-16 16 p., 3126.Research output: Contribution to journal › Article › peer-review
Open Access