Barbara Elaine Stranger

  • 21111 Citations
20022020

Research output per year

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Research Output

  • 21111 Citations
  • 62 Article
  • 12 Review article
  • 3 Comment/debate
  • 1 Editorial
2020

5-Hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease burden in children with neuroblastoma

Applebaum, M. A., Barr, E. K., Karpus, J., West-Szymanski, D. C., Oliva, M., Sokol, E. A., Zhang, S., Zhang, Z., Zhang, W., Chlenski, A., Salwen, H. R., Wilkinson, E., Dobratic, M., Grossman, R. L., Godley, L. A., Stranger, B. E., He, C. & Cohn, S. L., Mar 15 2020, In : Clinical Cancer Research. 26, 6, p. 1309-1317 9 p.

Research output: Contribution to journalArticle

Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation

Hernandez, W., Danahey, K., Pei, X., Yeo, K. T. J., Leung, E., Volchenboum, S. L., Ratain, M. J., Meltzer, D. O., Stranger, B. E., Perera, M. A. & O’Donnell, P. H., Feb 1 2020, In : Pharmacogenomics Journal. 20, 1, p. 126-135 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

5-Hydroxymethylcytosine profiles are prognostic of outcome in neuroblastoma and reveal transcriptional networks that correlate with tumor phenotype

Applebaum, M. A., Barr, E. K., Karpus, J., Nie, J., Zhang, Z., Armstrong, A. E., Uppal, S., Sukhanova, M., Zhang, W., Chlenski, A., Salwen, H. R., Wilkinson, E., Dobratic, M., Grossman, R., Godley, L. A., Stranger, B. E., He, C. & Cohn, S. L., Jan 1 2019, In : JCO Precision Oncology. 3

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
1 Scopus citations

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Wellcome Trust Case Control Consortium, Cross-Disorder Group of the Psychiatric Genomics Consortium, 23andMe Research Team & Psychosis Endophenotypes International Consortium, Dec 12 2019, In : Cell. 179, 7, p. 1469-1482.e11

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

ImmGen report: sexual dimorphism in the immune system transcriptome

Gal-Oz, S. T., Maier, B., Yoshida, H., Seddu, K., Elbaz, N., Czysz, C., Zuk, O., Stranger, B. E., Ner-Gaon, H. & Shay, T., Dec 1 2019, In : Nature communications. 10, 1, 4295.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Sex differences in gene expression in response to ischemia in the human left ventricular myocardium

Stone, G., Choi, A., Meritxell, O., Gorham, J., Heydarpour, M., Seidman, C. E., Seidman, J. G., Aranki, S. F., Body, S. C., Carey, V. J., Raby, B. A., Stranger, B. E. & Muehlschlegel, J. D., Jan 1 2019, In : Human molecular genetics. 28, 10, p. 1682-1693 12 p., ddz014.

Research output: Contribution to journalArticle

6 Scopus citations

Sex differences in the genetic architecture of obsessive–compulsive disorder

Tourette Syndrome/Obsessive-Compulsive Disorder Working Group of the Psychiatric Genomics Consortium, Jan 1 2019, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 6, p. 351-364 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

The new science of sex differences in neuropsychiatric traits

Davis, L. K. & Stranger, B. E., Jan 1 2019, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 6, p. 333-334 2 p.

Research output: Contribution to journalEditorial

The role of sex in the genomics of human complex traits

Khramtsova, E. A., Davis, L. K. & Stranger, B. E., Mar 1 2019, In : Nature Reviews Genetics. 20, 3, p. 173-190 18 p.

Research output: Contribution to journalReview article

32 Scopus citations
2018

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

Barbeira, A. N., Dickinson, S. P., Bonazzola, R., Zheng, J., Wheeler, H. E., Torres, J. M., Torstenson, E. S., Shah, K. P., Garcia, T., Edwards, T. L., Stahl, E. A., Huckins, L. M., Aguet, F., Ardlie, K. G., Cummings, B. B., Gelfand, E. T., Getz, G., Hadley, K., Handsaker, R. E., Huang, K. H. & 225 others, Kashin, S., Karczewski, K. J., Lek, M., Li, X., MacArthur, D. G., Nedzel, J. L., Nguyen, D. T., Noble, M. S., Segrè, A. V., Trowbridge, C. A., Tukiainen, T., Abell, N. S., Balliu, B., Barshir, R., Basha, O., Battle, A., Bogu, G. K., Brown, A., Brown, C. D., Castel, S. E., Chen, L. S., Chiang, C., Conrad, D. F., Damani, F. N., Davis, J. R., Delaneau, O., Dermitzakis, E. T., Engelhardt, B. E., Eskin, E., Ferreira, P. G., Frésard, L., Gamazon, E. R., Garrido-Martín, D., Gewirtz, A. D. H., Gliner, G., Gloudemans, M. J., Guigo, R., Hall, I. M., Han, B., He, Y., Hormozdiari, F., Howald, C., Jo, B., Kang, E. Y., Kim, Y., Kim-Hellmuth, S., Lappalainen, T., Li, G., Li, X., Liu, B., Mangul, S., McCarthy, M. I., McDowell, I. C., Mohammadi, P., Monlong, J., Montgomery, S. B., Muñoz-Aguirre, M., Ndungu, A. W., Nobel, A. B., Oliva, M., Ongen, H., Palowitch, J. J., Panousis, N., Papasaikas, P., Park, Y. S., Parsana, P., Payne, A. J., Peterson, C. B., Quan, J., Reverter, F., Sabatti, C., Saha, A., Sammeth, M., Scott, A. J., Shabalin, A. A., Sodaei, R., Stephens, M., Stranger, B. E., Strober, B. J., Sul, J. H., Tsang, E. K., Urbut, S., Van De Bunt, M., Wang, G., Wen, X., Wright, F. A., Xi, H. S., Yeger-Lotem, E., Zappala, Z., Zaugg, J. B., Zhou, Y. H., Akey, J. M., Bates, D., Chan, J., Claussnitzer, M., Demanelis, K., Diegel, M., Doherty, J. A., Feinberg, A. P., Fernando, M. S., Halow, J., Hansen, K. D., Haugen, E., Hickey, P. F., Hou, L., Jasmine, F., Jian, R., Jiang, L., Johnson, A., Kaul, R., Kellis, M., Kibriya, M. G., Lee, K., Li, J. B., Li, Q., Lin, J., Lin, S., Linder, S., Linke, C., Liu, Y., Maurano, M. T., Molinie, B., Nelson, J., Neri, F. J., Park, Y., Pierce, B. L., Rinaldi, N. J., Rizzardi, L. F., Sandstrom, R., Skol, A., Smith, K. S., Snyder, M. P., Stamatoyannopoulos, J., Tang, H., Wang, L., Wang, M., Van Wittenberghe, N., Wu, F., Zhang, R., Nierras, C. R., Branton, P. A., Carithers, L. J., Guan, P., Moore, H. M., Rao, A., Vaught, J. B., Gould, S. E., Lockart, N. C., Martin, C., Struewing, J. P., Volpi, S., Addington, A. M., Koester, S. E., Little, A. R., Brigham, L. E., Hasz, R., Hunter, M., Johns, C., Johnson, M., Kopen, G., Leinweber, W. F., Lonsdale, J. T., McDonald, A., Mestichelli, B., Myer, K., Roe, B., Salvatore, M., Shad, S., Thomas, J. A., Walters, G., Washington, M., Wheeler, J., Bridge, J., Foster, B. A., Gillard, B. M., Karasik, E., Kumar, R., Miklos, M., Moser, M. T., Jewell, S. D., Montroy, R. G., Rohrer, D. C., Valley, D. R., Davis, D. A., Mash, D. C., Undale, A. H., Smith, A. M., Tabor, D. E., Roche, N. V., McLean, J. A., Vatanian, N., Robinson, K. L., Sobin, L., Barcus, M. E., Valentino, K. M., Qi, L., Hunter, S., Hariharan, P., Singh, S., Um, K. S., Matose, T., Tomaszewski, M. M., Barker, L. K., Mosavel, M., Siminoff, L. A., Traino, H. M., Flicek, P., Juettemann, T., Ruffier, M., Sheppard, D., Taylor, K., Trevanion, S. J., Zerbino, D. R., Craft, B., Goldman, M., Haeussler, M., Kent, W. J., Lee, C. M., Paten, B., Rosenbloom, K. R., Vivian, J., Zhu, J., Nicolae, D. L., Cox, N. J. & Im, H. K., Dec 1 2018, In : Nature communications. 9, 1, 1825.

Research output: Contribution to journalArticle

Open Access
114 Scopus citations

Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection

Ye, C. J., Chen, J., Villani, A. C., Gate, R. E., Subramaniam, M., Bhangale, T., Lee, M. N., Raj, T., Raychowdhury, R., Li, W., Rogel, N., Simmons, S., Imboywa, S. H., Chipendo, P. I., McCabe, C., Lee, M. H., Frohlich, I. Y., Stranger, B. E., De Jager, P. L., Regev, A. & 2 others, Behrens, T. & Hacohen, N., Dec 1 2018, In : Genome research. 28, 12, p. 1812-1825 14 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2017

Assocplots: a Python package for static and interactive visualization of multiple-group GWAS results

Khramtsova, E. A. & Stranger, B. E., Feb 1 2017, In : Bioinformatics (Oxford, England). 33, 3, p. 432-434 3 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research

Manolio, T. A., Fowler, D. M., Starita, L. M., Haendel, M. A., MacArthur, D. G., Biesecker, L. G., Worthey, E., Chisholm, R. L., Green, E. D., Jacob, H. J., McLeod, H. L., Roden, D., Rodriguez, L. L., Williams, M. S., Cooper, G. M., Cox, N. J., Herman, G. E., Kingsmore, S., Lo, C., Lutz, C. & 11 others, MacRae, C. A., Nussbaum, R. L., Ordovas, J. M., Ramos, E. M., Robinson, P. N., Rubinstein, W. S., Seidman, C., Stranger, B. E., Wang, H., Westerfield, M. & Bult, C., Mar 23 2017, In : Cell. 169, 1, p. 6-12 7 p.

Research output: Contribution to journalComment/debate

57 Scopus citations

Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease

Stranger, B. E., Brigham, L. E., Hasz, R., Hunter, M., Johns, C., Johnson, M., Kopen, G., Leinweber, W. F., Lonsdale, J. T., McDonald, A., Mestichelli, B., Myer, K., Roe, B., Salvatore, M., Shad, S., Thomas, J. A., Walters, G., Washington, M., Wheeler, J., Bridge, J. & 75 others, Foster, B. A., Gillard, B. M., Karasik, E., Kumar, R., Miklos, M., Moser, M. T., Jewell, S. D., Montroy, R. G., Rohrer, D. C., Valley, D. R., Davis, D. A., Mash, D. C., Gould, S. E., Guan, P., Koester, S., Little, A. R., Martin, C., Moore, H. M., Rao, A., Struewing, J. P., Volpi, S., Hansen, K. D., Hickey, P. F., Rizzardi, L. F., Hou, L., Liu, Y., Molinie, B., Park, Y., Rinaldi, N., Wang, L., Wittenberghe, N., Claussnitzer, M., Gelfand, E. T., Li, Q., Linder, S., Zhang, R., Smith, K. S., Tsang, E. K., Chen, L. S., Demanelis, K., Doherty, J. A., Farzana, J., Kibriya, M. G., Jiang, L., Lin, S., Wang, M., Jian, R., Li, X., Chan, J., Bates, D., Diegel, M., Halow, J., Haugen, E., Johnson, A., Kaul, R., Lee, K., Maurano, M. T., Nelson, J., Neri, F. J., Sandstrom, R., Fernando, M. S., Linke, C., Oliva, M., Skol, A., Wu, F., Akey, J. M., Feinberg, A. P., Billy, J. L., Pierce, B. L., Stamatoyannopoulos, J. A., Tang, H., Ardlie, K. G., Kellis, M., Snyder, M. P. & Montgomery, S. B., Dec 1 2017, In : Nature Genetics. 49, 12, p. 1664-1670 7 p.

Research output: Contribution to journalReview article

64 Scopus citations

Evaluation of Genetic Predisposition for MYCN-Amplified Neuroblastoma

Hungate, E. A., Applebaum, M. A., Skol, A. D., Vaksman, Z., Diamond, M., McDaniel, L., Volchenboum, S. L., Stranger, B. E., Maris, J. M., Diskin, S. J., Onel, K. & Cohn, S. L., Oct 1 2017, In : Journal of the National Cancer Institute. 109, 10

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Large-Scale trans-eQTLs Affect Hundreds of Transcripts and Mediate Patterns of Transcriptional Co-regulation

Brynedal, B., Choi, J. M., Raj, T., Bjornson, R., Stranger, B. E., Neale, B. M., Voight, B. F. & Cotsapas, C., Apr 6 2017, In : American journal of human genetics. 100, 4, p. 581-591 11 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Neuroblastoma survivors are at increased risk for second malignancies: A report from the International Neuroblastoma Risk Group Project

Applebaum, M. A., Vaksman, Z., Lee, S. M., Hungate, E. A., Henderson, T. O., London, W. B., Pinto, N., Volchenboum, S. L., Park, J. R., Naranjo, A., Hero, B., Pearson, A. D., Stranger, B. E., Cohn, S. L. & Diskin, S. J., Feb 1 2017, In : European Journal of Cancer. 72, p. 177-185 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2016

Genetic architecture of age-related cognitive decline in African Americans

Raj, T., Chibnik, L. B., McCabe, C., Wong, A., Replogle, J. M., Yu, L., Gao, S., Unverzagt, F. W., Stranger, B. E., Murrell, J., Barnes, L., Hendrie, H. C., Foroud, T., Krichevsky, A., Bennett, D. A., Hall, K. S., Evans, D. A. & De Jager, P. L., 2016, In : Neurology: Genetics. 3, 1, e125.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Imputing Gene Expression in Uncollected Tissues Within and beyond GTEx

Wang, J., Gamazon, E. R., Pierce, B. L., Stranger, B. E., Im, H. K., Gibbons, R. D., Cox, N. J., Nicolae, D. L. & Chen, L. S., Apr 7 2016, In : American journal of human genetics. 98, 4, p. 697-708 12 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients

Applebaum, M. A., Jha, A. R., Kao, C., Hernandez, K. M., DeWane, G., Salwen, H. R., Chlenski, A., Dobratic, M., Mariani, C. J., Godley, L. A., Prabhakar, N., White, K., Stranger, B. E. & Cohn, S. L., 2016, In : Oncotarget. 7, 47, p. 76816-76826 11 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
2015

Accurate and Fast Multiple-Testing Correction in eQTL Studies

Sul, J. H., Raj, T., de Jong, S., de Bakker, P. I. W., Raychaudhuri, S., Ophoff, R. A., Stranger, B. E., Eskin, E. & Han, B., May 1 2015, In : American journal of human genetics. 96, 6, p. 857-868 12 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Design and implementation of the international genetics and translational research in transplantation network

The International Genetics & Translational Research in Transplantation Network (iGeneTRAiN), Oct 23 2015, In : Transplantation. 99, 11, p. 2401-2412 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

Trynka, G., Westra, H. J., Slowikowski, K., Hu, X., Xu, H., Stranger, B. E., Klein, R. J., Han, B. & Raychaudhuri, S., Jan 1 2015, In : American journal of human genetics. 97, 1, p. 139-152 14 p.

Research output: Contribution to journalArticle

Open Access
61 Scopus citations

Expression quantitative trait loci information improves predictive modeling of disease relevance of non-coding genetic variation

Croteau-Chonka, D. C., Rogers, A. J., Raj, T., McGeachie, M. J., Qiu, W., Ziniti, J. P., Stubbs, B. J., Liang, L., Martinez, F. D., Strunk, R. C., Lemanske, R. F., Liu, A. H., Stranger, B. E., Carey, V. J. & Raby, B. A., Oct 16 2015, In : PloS one. 10, 10, 140758.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes

Tilburgs, T., Crespo, Â. C., Van Der Zwan, A., Rybalov, B., Raj, T., Stranger, B. E., Gardner, L., Moffett, A. & Strominger, J. L., Jun 9 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 23, p. 7219-7224 6 p.

Research output: Contribution to journalArticle

Open Access
71 Scopus citations

ImmVar project: Insights and design considerations for future studies of "healthy" immune variation

De Jager, P. L., Hacohen, N., Mathis, D., Regev, A., Stranger, B. E. & Benoist, C., Feb 1 2015, In : Seminars in Immunology. 27, 1, p. 51-57 7 p.

Research output: Contribution to journalReview article

29 Scopus citations

The impact of human copy number variation on gene expression

Gamazon, E. R. & Stranger, B. E., Sep 1 2015, In : Briefings in Functional Genomics. 14, 5, p. 352-357 6 p., elv017.

Research output: Contribution to journalArticle

Open Access
50 Scopus citations

The transcriptional landscape of age in human peripheral blood

Peters, M. J., Joehanes, R., Pilling, L. C., Schurmann, C., Conneely, K. N., Powell, J., Reinmaa, E., Sutphin, G. L., Zhernakova, A., Schramm, K., Wilson, Y. A., Kobes, S., Tukiainen, T., Ramos, Y. F., Göring, H. H. H., Fornage, M., Liu, Y., Gharib, S. A., Stranger, B. E., De Jager, P. L. & 117 others, Aviv, A., Levy, D., Murabito, J. M., Munson, P. J., Huan, T., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Van Rooij, J., Stolk, L., Broer, L., Verbiest, M. M. P. J., Jhamai, M., Arp, P., Metspalu, A., Tserel, L., Milani, L., Samani, N. J., Peterson, P., Kasela, S., Codd, V., Peters, A., Ward-Caviness, C. K., Herder, C., Waldenberger, M., Roden, M., Singmann, P., Zeilinger, S., Illig, T., Homuth, G., Grabe, H. J., Völzke, H., Steil, L., Kocher, T., Murray, A., Melzer, D., Yaghootkar, H., Bandinelli, S., Moses, E. K., Kent, J. W., Curran, J. E., Johnson, M. P., Williams-Blangero, S., Westra, H. J., McRae, A. F., Smith, J. A., Kardia, S. L. R., Hovatta, I., Perola, M., Ripatti, S., Salomaa, V., Henders, A. K., Martin, N. G., Smith, A. K., Mehta, D., Binder, E. B., Nylocks, K. M., Kennedy, E. M., Klengel, T., Ding, J., Suchy-Dicey, A. M., Enquobahrie, D. A., Brody, J., Rotter, J. I., Chen, Y. D. I., Houwing-Duistermaat, J., Kloppenburg, M., Slagboom, P. E., Helmer, Q., Den Hollander, W., Bean, S., Raj, T., Bakhshi, N., Wang, Q. P., Oyston, L. J., Psaty, B. M., Tracy, R. P., Montgomery, G. W., Turner, S. T., Blangero, J., Meulenbelt, I., Ressler, K. J., Yang, J., Franke, L., Kettunen, J., Visscher, P. M., Neely, G. G., Korstanje, R., Hanson, R. L., Prokisch, H., Ferrucci, L., Esko, T., Teumer, A., Van Meurs, J. B. J., Johnson, A. D., Nalls, M. A., Hernandez, D. G., Cookson, M. R., Gibbs, R. J., Hardy, J., Ramasamy, A., Zonderman, A. B., Dillman, A., Traynor, B., Smith, C., Longo, D. L., Trabzuni, D., Troncoso, J., Van Der Brug, M., Weale, M. E., O'Brien, R., Johnson, R., Walker, R., Zielke, R. H., Arepalli, S., Ryten, M. & Singleton, A. B., Oct 22 2015, In : Nature communications. 6, 8570.

Research output: Contribution to journalArticle

Open Access
194 Scopus citations
2014

CD33: Increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility

Raj, T., Ryan, K. J., Replogle, J. M., Chibnik, L. B., Rosenkrantz, L., Tang, A., Rothamel, K., Stranger, B. E., Bennett, D. A., Evans, D. A., De Jager, P. L. & Bradshaw, E. M., May 2014, In : Human molecular genetics. 23, 10, p. 2729-2736 8 p., ddt666.

Research output: Contribution to journalArticle

53 Scopus citations

Common genetic variants modulate pathogen-sensing responses in human dendritic cells

Lee, M. N., Ye, C., Villani, A. C., Raj, T., Li, W., Eisenhaure, T. M., Imboywa, S. H., Chipendo, P. I., Ran, F. A., Slowikowski, K., Ward, L. D., Raddassi, K., McCabe, C., Lee, M. H., Frohlich, I. Y., Hafler, D. A., Kellis, M., Raychaudhuri, S., Zhang, F., Stranger, B. E. & 4 others, Benoist, C. O., De Jager, P. L., Regev, A. & Hacohen, N., 2014, In : Science. 343, 6175, 1246980.

Research output: Contribution to journalArticle

227 Scopus citations

Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types

Li, Q., Stram, A., Chen, C., Kar, S., Gayther, S., Pharoah, P., Haiman, C., Stranger, B. E., Kraft, P. & Freedman, M. L., Oct 1 2014, In : Human molecular genetics. 23, 19, p. 5294-5302 9 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Okada, Y., Wu, D., Trynka, G., Raj, T., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., Suzuki, A., Yoshida, S., Graham, R. R., Manoharan, A., Ortmann, W., Bhangale, T., Denny, J. C., Carroll, R. J., Eyler, A. E., Greenberg, J. D., Kremer, J. M., Pappas, D. A. & 75 others, Jiang, L., Yin, J., Ye, L., Su, D. F., Yang, J., Xie, G., Keystone, E., Westra, H. J., Esko, T., Metspalu, A., Zhou, X., Gupta, N., Mirel, D., Stahl, E. A., Diogo, D., Cui, J., Liao, K., Guo, M. H., Myouzen, K., Kawaguchi, T., Coenen, M. J. H., Van Riel, P. L. C. M., Van De Laar, M. A. F. J., Guchelaar, H. J., Huizinga, T. W. J., Dieudé, P., Mariette, X., Bridges, S. L., Zhernakova, A., Toes, R. E. M., Tak, P. P., Miceli-Richard, C., Bang, S. Y., Lee, H. S., Martin, J., Gonzalez-Gay, M. A., Rodriguez-Rodriguez, L., Rantapää-Dahlqvist, S., Ärlestig, L., Choi, H. K., Kamatani, Y., Galan, P., Lathrop, M., Eyre, S., Bowes, J., Barton, A., De Vries, N., Moreland, L. W., Criswell, L. A., Karlson, E. W., Taniguchi, A., Yamada, R., Kubo, M., Liu, J. S., Bae, S. C., Worthington, J., Padyukov, L., Klareskog, L., Gregersen, P. K., Raychaudhuri, S., Stranger, B. E., De Jager, P. L., Franke, L., Visscher, P. M., Brown, M. A., Yamanaka, H., Mimori, T., Takahashi, A., Xu, H., Behrens, T. W., Siminovitch, K. A., Momohara, S., Matsuda, F., Yamamoto, K. & Plenge, R. M., 2014, In : Nature. 506, 7488, p. 376-381 6 p.

Research output: Contribution to journalArticle

951 Scopus citations

Genomics of alternative splicing: Evolution, development and pathophysiology

Gamazon, E. R. & Stranger, B. E., Jan 1 2014, In : Human Genetics. 133, 6, p. 679-687 9 p.

Research output: Contribution to journalReview article

57 Scopus citations

Interindividual variation in human T regulatory cells

Ferraro, A., D'Alise, A. M., Raj, T., Asinovski, N., Phillips, R., Ergun, A., Replogle, J. M., Bernier, A., Laffel, L., Stranger, B. E., De Jager, P. L., Mathis, D. & Benoist, C., Mar 25 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 12, p. E1111-E1120

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Intersection of population variation and autoimmunity genetics in human T cell activation

Ye, C. J., Feng, T., Kwon, H. K., Raj, T., Wilson, M. T., Asinovski, N., McCabe, C., Lee, M. H., Frohlich, I., Paik, H. I., Zaitlen, N., Hacohen, N., Stranger, B. E., De Jager, P., Mathis, D., Regev, A. & Benoist, C., Sep 12 2014, In : Science. 345, 6202, 1254665.

Research output: Contribution to journalArticle

120 Scopus citations

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

Raj, T., Rothamel, K., Mostafavi, S., Ye, C., Lee, M. N., Replogle, J. M., Feng, T., Lee, M., Asinovski, N., Frohlich, I., Imboywa, S., Von Korff, A., Okada, Y., Patsopoulos, N. A., Davis, S., McCabe, C., Paik, H. I., Srivastava, G. P., Raychaudhuri, S., Hafler, D. A. & 7 others, Koller, D., Regev, A., Hacohen, N., Mathis, D., Benoist, C., Stranger, B. E. & De Jager, P. L., Jan 1 2014, In : Science. 344, 6183, p. 519-523 5 p.

Research output: Contribution to journalArticle

254 Scopus citations

Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells

Hu, X., Kim, H., Raj, T., Brennan, P. J., Trynka, G., Teslovich, N., Slowikowski, K., Chen, W. M., Onengut, S., Baecher-Allan, C., De Jager, P. L., Rich, S. S., Stranger, B. E., Brenner, M. B. & Raychaudhuri, S., Jun 2014, In : PLoS genetics. 10, 6, e1004404.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations
2013

Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human-Neandertal Divergence

Gokcumen, O., Zhu, Q., Mulder, L. C. F., Iskow, R. C., Austermann, C., Scharer, C. D., Raj, T., Boss, J. M., Sunyaev, S., Price, A., Stranger, B. E., Simon, V. & Lee, C., Apr 2013, In : PLoS genetics. 9, 4, e1003404.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Chromatin marks identify critical cell types for fine mapping complex trait variants

Trynka, G., Sandor, C., Han, B., Xu, H., Stranger, B. E., Liu, X. S. & Raychaudhuri, S., Feb 1 2013, In : Nature Genetics. 45, 2, p. 124-130 7 p.

Research output: Contribution to journalArticle

304 Scopus citations

Common risk alleles for inflammatory diseases are targets of recent positive selection

Raj, T., Kuchroo, M., Replogle, J. M., Raychaudhuri, S., Stranger, B. E. & De Jager, P. L., Apr 4 2013, In : American journal of human genetics. 92, 4, p. 517-529 13 p.

Research output: Contribution to journalArticle

Open Access
72 Scopus citations

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

Patsopoulos, N. A., Barcellos, L. F., Hintzen, R. Q., Schaefer, C., van Duijn, C. M., Noble, J. A., Raj, T., Gourraud, P. A., Stranger, B. E., Oksenberg, J., Olsson, T., Taylor, B. V., Sawcer, S., Hafler, D. A., Carrington, M., De Jager, P. L., de Bakker, P. I. W., Bernardinelli, L., Booth, D., Comabella, M. & 43 others, Compston, A., D'Alfonso, S., Fontaine, B., Goris, A., Haines, J., Harbo, H., Hauser, S., Hawkins, C., Hemmer, B., Ivinson, A., Lill, C., Martin, R., Martinelli-Boneschi, F., Oturai, A., Palotie, A., PericakVance, M., Saarela, J., Stewart, G., Zipp, F., Scott, R. J., Lechner-Scott, J., Moscato, P., Booth, D. R., Stewart, G. J., Heard, R. N., Mason, D., Griffiths, L., Broadley, S., Brown, M. A., Slee, M., Foote, S. J., Stankovich, J., Taylor, B. V., Wiley, J., Bahlo, M., Perreau, V., Field, J., Butzkueven, H., Kilpatrick, T. J., Rubio, J., Marriott, M., Carroll1, W. M. & Kermode, A. G., Nov 1 2013, In : PLoS genetics. 9, 11, e1003926.

Research output: Contribution to journalArticle

Open Access
140 Scopus citations

Genetics of human gene expression

Stranger, B. E. & Raj, T., Dec 1 2013, In : Current Opinion in Genetics and Development. 23, 6, p. 627-634 8 p.

Research output: Contribution to journalReview article

13 Scopus citations

Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis

Cui, J., Stahl, E. A., Saevarsdottir, S., Miceli, C., Diogo, D., Trynka, G., Raj, T., Mirkov, M. U., Canhao, H., Ikari, K., Terao, C., Okada, Y., Wedrén, S., Askling, J., Yamanaka, H., Momohara, S., Taniguchi, A., Ohmura, K., Matsuda, F., Mimori, T. & 36 others, Gupta, N., Kuchroo, M., Morgan, A. W., Isaacs, J. D., Wilson, A. G., Hyrich, K. L., Herenius, M., Doorenspleet, M. E., Tak, P. P., Crusius, J. B. A., van der Horst-Bruinsma, I. E., Wolbink, G. J., van Riel, P. L. C. M., van de Laar, M., Guchelaar, H. J., Shadick, N. A., Allaart, C. F., Huizinga, T. W. J., Toes, R. E. M., Kimberly, R. P., Bridges, S. L., Criswell, L. A., Moreland, L. W., Fonseca, J. E., de Vries, N., Stranger, B. E., De Jager, P. L., Raychaudhuri, S., Weinblatt, M. E., Gregersen, P. K., Mariette, X., Barton, A., Padyukov, L., Coenen, M. J. H., Karlson, E. W. & Plenge, R. M., 2013, In : PLoS genetics. 9, 3, e1003394.

Research output: Contribution to journalArticle

Open Access
108 Scopus citations

Integrative eQTL-based analyses reveal the biology of breast cancer risk loci

Li, Q., Seo, J. H., Stranger, B. E., McKenna, A., Pe'Er, I., Laframboise, T., Brown, M., Tyekucheva, S. & Freedman, M. L., Jan 31 2013, In : Cell. 152, 3, p. 633-641 9 p.

Research output: Contribution to journalArticle

Open Access
203 Scopus citations
2012

Alzheimer disease susceptibility loci: Evidence for a protein network under natural selection

Raj, T., Shulman, J. M., Keenan, B. T., Chibnik, L. B., Evans, D. A., Bennett, D. A., Stranger, B. E. & De Jager, P. L., Apr 6 2012, In : American Journal of Human Genetics. 90, 4, p. 720-726 7 p.

Research output: Contribution to journalArticle

Open Access
46 Scopus citations

Analysis of case-control association studies with known risk variants

Zaitlen, N., Paşaniuc, B., Patterson, N., Pollack, S., Voight, B., Groop, L., Altshuler, D., Henderson, B. E., Kolonel, L. N., Marchand, L. L., Waters, K., Haiman, C. A., Stranger, B. E., Dermitzakis, E. T., Kraft, P. & Price, A. L., Jul 2012, In : Bioinformatics. 28, 13, p. 1729-1737 9 p., bts259.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Coordinating GWAS results with gene expression in a systems immunologic paradigm in autoimmunity

Stranger, B. E. & De Jager, P. L., Oct 1 2012, In : Current Opinion in Immunology. 24, 5, p. 544-551 8 p.

Research output: Contribution to journalReview article

13 Scopus citations

Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis

Brown, K. H., Dobrinski, K. P., Lee, A. S., Gokcumen, O., Mills, R. E., Shi, X., Chong, W. W. S., Chen, J. Y. H., Yoo, P., David, S., Peterson, S. M., Raj, T., Choy, K. W., Stranger, B. E., Williamson, R. E., Zon, L. I., Freeman, J. L. & Lee, C., Jan 10 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 2, p. 529-534 6 p.

Research output: Contribution to journalArticle

Open Access
66 Scopus citations

Patterns of Cis regulatory variation in diverse human populations

Stranger, B. E., Montgomery, S. B., Dimas, A. S., Parts, L., Stegle, O., Ingle, C. E., Sekowska, M., Smith, G. D., Evans, D., Gutierrez-Arcelus, M., Price, A., Raj, T., Nisbett, J., Nica, A. C., Beazley, C., Durbin, R., Deloukas, P. & Dermitzakis, E. T., Apr 2012, In : PLoS genetics. 8, 4, e1002639.

Research output: Contribution to journalArticle

Open Access
305 Scopus citations