• 6184 Citations
1985 …2050

Research output per year

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Personal profile

Research Interests

I completed my fellowship at the Combined Program in Pediatric Gastroenterology at Harvard Medical School. I then join the faculty at Children's Hospital Boston and Harvard Medical School and continued a research fellowship in the laboratory of Dr. Stephen Galli at the Beth Israel Deaconess Medical Center. In 2000, I joined the faculty at the SUNY Downstate as the Vice-Chairman of Research and Education, and then in 2003 became the Division Director for Pediatric GI at the Children's Hospital at Montefiore and Albert Einstein College of Medicine. In 2008, I joined the faculty at Feinberg and Lurie Children's Hospital as the Chief of Gastroenterology, Hepatology, and Nutrition

My laboratory has a longstanding interest in mast cell and eosinophil biology. We have developed specific and novel in vivo approaches for the analysis of mast cell function in experimental gastrointestinal inflammatory and allergic reactions. We can apply this model to determine the precise influence of mast cells and mast cell-derived cytokines/chemokines in gastrointestinal inflammation.

My clinical research interest is eosinophilic esophagitis and involves efforts to improve the diagnostic and treatment options for patients

Certifications and Licenses

Pediatric Gastroenterology

Training Experience

1983Residency, Saint Louis Children's Hospital
1986Fellowship, Children's Hospital-Boston

Education/Academic qualification

MD, Washington University St. Louis

… → 1979

Research interests

  • Allergies
  • Digestive System (including gallbladder and liver)
  • Immunology
  • Inflammation

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Research Output

Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)

Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 28-37 10 p.

Research output: Contribution to journalArticle

  • Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites

    Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jul 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 130-138.e1

    Research output: Contribution to journalArticle

  • 13 Scopus citations
  • 16 Scopus citations

    Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis

    Wechsler, J. B., Szabo, A., Hsu, C. L., Krier-Burris, R. A., Schroeder, H. A., Wang, M. Y., Carter, R. G., Velez, T. E., Aguiniga, L. M., Brown, J. B., Miller, M. L., Wershil, B. K., Barrett, T. A. & Bryce, P. J., May 1 2018, In : Mucosal Immunology. 11, 3, p. 861-870 10 p.

    Research output: Contribution to journalArticle

  • 10 Scopus citations

    Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference

    Dellon, E. S., Liacouras, C. A., Molina-Infante, J., Furuta, G. T., Spergel, J. M., Zevit, N., Spechler, S. J., Attwood, S. E., Straumann, A., Aceves, S. S., Alexander, J. A., Atkins, D., Arva, N. C., Blanchard, C., Bonis, P. A., Book, W. M., Capocelli, K. E., Chehade, M., Cheng, E., Collins, M. H. & 46 others, Davis, C. M., Dias, J. A., Di Lorenzo, C., Dohil, R., Dupont, C., Falk, G. W., Ferreira, C. T., Fox, A., Gonsalves, N. P., Gupta, S. K., Katzka, D. A., Kinoshita, Y., Menard-Katcher, C., Kodroff, E., Metz, D. C., Miehlke, S., Muir, A. B., Mukkada, V. A., Murch, S., Nurko, S., Ohtsuka, Y., Orel, R., Papadopoulou, A., Peterson, K. A., Philpott, H., Putnam, P. E., Richter, J. E., Rosen, R., Rothenberg, M. E., Schoepfer, A., Scott, M. M., Shah, N., Sheikh, J., Souza, R. F., Strobel, M. J., Talley, N. J., Vaezi, M. F., Vandenplas, Y., Vieira, M. C., Walker, M. M., Wechsler, J. B., Wershil, B. K., Wen, T., Yang, G-Y., Hirano, I. & Bredenoord, A. J., Oct 2018, In : Gastroenterology. 155, 4, p. 1022-1033.e10

    Research output: Contribution to journalArticle

  • 114 Scopus citations