Grants per year
Personal profile
Research Interests
I completed my fellowship at the Combined Program in Pediatric Gastroenterology at Harvard Medical School. I then join the faculty at Children's Hospital Boston and Harvard Medical School and continued a research fellowship in the laboratory of Dr. Stephen Galli at the Beth Israel Deaconess Medical Center. In 2000, I joined the faculty at the SUNY Downstate as the Vice-Chairman of Research and Education, and then in 2003 became the Division Director for Pediatric GI at the Children's Hospital at Montefiore and Albert Einstein College of Medicine. In 2008, I joined the faculty at Feinberg and Lurie Children's Hospital as the Chief of Gastroenterology, Hepatology, and Nutrition
My laboratory has a longstanding interest in mast cell and eosinophil biology. We have developed specific and novel in vivo approaches for the analysis of mast cell function in experimental gastrointestinal inflammatory and allergic reactions. We can apply this model to determine the precise influence of mast cells and mast cell-derived cytokines/chemokines in gastrointestinal inflammation.
My clinical research interest is eosinophilic esophagitis and involves efforts to improve the diagnostic and treatment options for patients
Certifications and Licenses
Pediatrics | |
Pediatric Gastroenterology |
Training Experience
1983 | Residency, Saint Louis Children's Hospital |
1986 | Fellowship, Children's Hospital-Boston |
Education/Academic qualification
MD, Washington University
… → 1979
Research interests
- Allergies
- Digestive System (including gallbladder and liver)
- Immunology
- Inflammation
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Network
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Grants 2012 2018
- 5 Finished
FARE Clinical Network
Pongracic, J. A. & Wershil, B. K.
Food Allergy Research and Education
7/1/15 → 6/30/18
Project: Research project
Molecular Targeting of Dietary Therapy for Eosinophilic Esophagitis
Campaign Urging Research for Eosinophilic Disease (CURED)
9/1/14 → 8/31/18
Project: Research project
Consortium of Eosinophilic Gastrointestinal Disease Researchers
Cincinnati Children's Hospital Medical Center
8/15/14 → 7/31/18
Project: Research project
Consortium of Eosinophilic Gastrointestinal Disease Researchers
Northwestern University, National Institute of Diabetes & Digestive & Kidney
8/15/14 → 7/31/17
Project: Research project
Research Output 1985 2018
Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites
Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jul 1 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 130-138.e1Research output: Contribution to journal › Article
Eosinophilic Esophagitis Reference Score Accurately Identifies Disease Activity and Treatment Effects in Children
Wechsler, J. B., Bolton, S. M., Amsden, K., Wershil, B. K., Hirano, I. & Kagalwalla, A. F., Jul 1 2018, In : Clinical Gastroenterology and Hepatology. 16, 7, p. 1056-1063 8 p.Research output: Contribution to journal › Article
Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis
Wechsler, J. B., Szabo, A., Hsu, C. L., Krier-Burris, R. A., Schroeder, H. A., Wang, M. Y., Carter, R. G., Velez, T. E., Aguiniga, L. M., Brown, J. B., Miller, M. L., Wershil, B. K., Barrett, T. A. & Bryce, P. J., May 1 2018, In : Mucosal Immunology. 11, 3, p. 861-870 10 p.Research output: Contribution to journal › Article
Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference
Dellon, E. S., Liacouras, C. A., Molina-Infante, J., Furuta, G. T., Spergel, J. M., Zevit, N., Spechler, S. J., Attwood, S. E., Straumann, A., Aceves, S. S., Alexander, J. A., Atkins, D., Arva, N. C., Blanchard, C., Bonis, P. A., Book, W. M., Capocelli, K. E., Chehade, M., Cheng, E., Collins, M. H. & 46 others, , Oct 2018, In : Gastroenterology. 155, 4, p. 1022-1033.e10Research output: Contribution to journal › Article
Efficacy of a 4-Food Elimination Diet for Children With Eosinophilic Esophagitis
Kagalwalla, A. F., Wechsler, J. B., Amsden, K., Schwartz, S., Makhija, M. M., Olive, A., Davis, C. M., Manuel-Rubio, M., Marcus, S., Shaykin, R., Sulkowski, M., Johnson, K., Ross, J. N., Riffle, M. E., Groetch, M., Melin-Aldana, H., Schady, D., Palac, H., Kim, K. Y. A., Wershil, B. K. & 2 others, , Nov 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 11, p. 1698-1707.e7Research output: Contribution to journal › Article