Bayar Thimmapaya

  • Source: Scopus
1990 …2018

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Personal profile

Research Interests

Our research focuses on cell cycle deregulation by DNA tumor virus oncogenes (Adenovirus E1A, Simian virus 40 large T, and human papilloma virus E6 and E7). In particular, we are interested to find out how binding of these viral tumor antigens to cellular proteins such as pRb, p300/CBP and other proteins affect G1/S phase transition. We use molecular genetic approaches to study these aspects. We also work on molecular mechanisms of liver cell proliferation and perturbations of these mechanisms that lead to liver cancer development. We are particularly interested in Ras induced liver cancer model and we focus on a few key proteins including Med1 (a subunit of the mediator complex) and FoxM1 which is involved in liver cancer development. Please see the link below to obtain complete list of publications: http://www.ncbi.nlm.nih.gov/sites/myncbi/1lKj3YJaj6L5G/bibliography/46771805/public/?sort=date&direction=ascending

Training Experience

1977Postdoctoral Fellowship, Yale University
1980Postdoctoral Fellowship, University of Connecticut
1980Postdoctoral Fellowship, SUNY/State University of New York, Stony Brook

Expertise related to UN Sustainable Devlopment Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Molecular Biology, PhD, Indian Institute of Science Bangalore

… → 1975

Research interests

  • Cancer Biology
  • DNA Repair
  • DNA Replication
  • Eukaryotic Cells
  • Gene Regulation
  • Genetics
  • Molecular Biology
  • Virology

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