Grants per year
Personal profile
Research Interests
Cancer immunology and immunotherapy. The Zhang laboratory functions as an integrated translational research program with the goal of designing and developing new immunotherapies and immunologic strategies for cancer treatment. The ongoing projects are focused on dissecting the molecular mechanisms used for tumor immune evasion based on the cutting-edge technical platforms.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Cell Biology, Chinese Academy of Medical Science & Peking Union Medical College
… → 2003
MD, Medicine, West China University
… → 1999
Research interests keywords
- Cancer Biology
- Drug Discovery
- Immune Regulation
- Nanotechnology
- Translational Research
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Network
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Co-targeting BET Bromodomain Proteins and MNK Kinases in Pancreatic Cancer
Munshi, H. G., Bentrem, D. J., Shields, M. & Zhang, B.
4/1/22 → 3/31/27
Project: Research project
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Immuno Core
University of California, San Francisco, National Cancer Institute
9/10/21 → 8/31/26
Project: Research project
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Infection-Associated Cancer Research Training Program in Mali
Hou, L., Maiga, M., Kim, K. A., Murphy, R. L., Wei, J. & Zhang, B.
7/1/21 → 6/30/26
Project: Research project
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Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity
Fu, Z., Chen, S., Zhu, Y., Zhang, D., Xie, P., Jiao, Q., Chi, J., Xu, S., Xue, Y., Lu, X., Song, X., Cristofanilli, M., Gradishar, W. J., Kalinsky, K., Yin, Y., Zhang, B. & Wan, Y., Jan 2023, In: Science Advances. 9, 1, eadd6626.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Disrupting the Interplay between Programmed Cell Death Protein 1 and Programmed Death Ligand 1 with Spherical Nucleic Acids in Treating Cancer
Chou, L., Callmann, C. E., Dominguez, D., Zhang, B. & Mirkin, C. A., Sep 28 2022, In: ACS Central Science. 8, 9, p. 1299-1305 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial: Development and Potential Mechanisms of Low Molecular Weight Drugs for Cancer Immunotherapy
Gao, Y., Yang, X. & Zhang, B., May 17 2022, In: Frontiers in immunology. 13, 920442.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Epigenetic priming enhances antitumor immunity in platinum-resistant ovarian cancer
Chen, S., Xie, P., Cowan, M., Huang, H., Cardenas, H., Keathley, R., Tanner, E. J., Fleming, G. F., Moroney, J. W., Pant, A., Akasha, A. M., Davuluri, R. V., Kocherginsky, M., Zhang, B. & Matei, D., Jul 15 2022, In: Journal of Clinical Investigation. 132, 14, e158800.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
A Series of RET Fusion Spitz Neoplasms With Plaque-Like Silhouette and Dyscohesive Nesting of Epithelioid Melanocytes
Kim, D., Compres, E. V., Zhang, B., Khan, A. U., Sunshine, J. C., Quan, V. L. & Gerami, P., Apr 1 2021, In: American Journal of Dermatopathology. 43, 4, p. 243-251 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Datasets
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Cancer-cell-secreted CXCL11 promoted CD8+ T cells infiltration through docetaxel-induced-release of HMGB1 in NSCLC
Gao, Q. (Creator), Wang, S. (Creator), Chen, X. (Contributor), Cheng, S. (Contributor), Zhang, Z. (Creator), Li, F. (Creator), Huang, L. (Creator), Yang, Y. (Creator), Zhou, B. (Creator), Yue, D. (Contributor), Wang, D. (Creator), Cao, L. (Creator), Maimela, N. R. (Contributor), Zhang, B. (Creator), Yu, J. (Creator), Wang, L. (Creator) & Zhang, Y. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4397342.v1, https://springernature.figshare.com/collections/Cancer-cell-secreted_CXCL11_promoted_CD8_T_cells_infiltration_through_docetaxel-induced-release_of_HMGB1_in_NSCLC/4397342/1
Dataset
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Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy
Basher, F. (Contributor), Dhar, P. (Contributor), Wang, X. (Creator), Wainwright, D. A. (Creator), Zhang, B. (Creator), Sosman, J. A. (Creator), Ji, Z. (Creator) & Wu, J. D. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.c.5014769.v2, https://springernature.figshare.com/collections/Antibody_targeting_tumor-derived_soluble_NKG2D_ligand_sMIC_reprograms_NK_cell_homeostatic_survival_and_function_and_enhances_melanoma_response_to_PDL1_blockade_therapy/5014769/2
Dataset
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Antibody targeting tumor-derived soluble NKG2D ligand sMIC provides dual co-stimulation of CD8 T cells and enables sMIC+ tumors respond to PD1/PD-L1 blockade therapy
Zhang, J. (Creator), Larrocha, P. S. (Creator), Zhang, B. (Creator), Wainwright, D. (Creator), Dhar, P. (Contributor) & Wu, J. D. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4643378, https://springernature.figshare.com/collections/Antibody_targeting_tumor-derived_soluble_NKG2D_ligand_sMIC_provides_dual_co-stimulation_of_CD8_T_cells_and_enables_sMIC_tumors_respond_to_PD1_PD-L1_blockade_therapy/4643378
Dataset
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Antibody targeting tumor-derived soluble NKG2D ligand sMIC provides dual co-stimulation of CD8 T cells and enables sMIC+ tumors respond to PD1/PD-L1 blockade therapy
Zhang, J. (Creator), Larrocha, P. S. (Creator), Zhang, B. (Creator), Wainwright, D. (Creator), Dhar, P. (Contributor) & Wu, J. D. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4643378.v1, https://springernature.figshare.com/collections/Antibody_targeting_tumor-derived_soluble_NKG2D_ligand_sMIC_provides_dual_co-stimulation_of_CD8_T_cells_and_enables_sMIC_tumors_respond_to_PD1_PD-L1_blockade_therapy/4643378/1
Dataset
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Additional file of Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy
Basher, F. (Contributor), Dhar, P. (Contributor), Wang, X. (Creator), Wainwright, D. A. (Creator), Zhang, B. (Creator), Sosman, J. A. (Creator), Ji, Z. (Creator) & Wu, J. D. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.12872204.v1, https://springernature.figshare.com/articles/dataset/Additional_file_of_Antibody_targeting_tumor-derived_soluble_NKG2D_ligand_sMIC_reprograms_NK_cell_homeostatic_survival_and_function_and_enhances_melanoma_response_to_PDL1_blockade_therapy/12872204/1
Dataset