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Personal profile

Research Interests

Cancer immunology and immunotherapy. The Zhang laboratory functions as an integrated translational research program with the goal of designing and developing new immunotherapies and immunologic strategies for cancer treatment. The ongoing projects are focused on dissecting the molecular mechanisms used for tumor immune evasion based on the cutting-edge technical platforms.

Education/Academic qualification

PhD, Chinese Academy of Medical Science & Peking Union Medical College

… → 2003

MD, West China University

… → 1999

Research interests

  • Cancer Biology
  • Drug Discovery
  • Immune Regulation
  • Nanotechnology
  • Translational Research

Fingerprint Dive into the research topics where Bin Zhang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Neoplasms Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Immunity Medicine & Life Sciences
Interleukin-18 Medicine & Life Sciences
Tumor Microenvironment Medicine & Life Sciences
Regulatory T-Lymphocytes Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2011 2023

Triple Negative Breast Neoplasms
Phosphotransferases
Neoplasms
Therapeutics
T-Lymphocytes
Immunologic Factors
Neoplasms
Tumor Microenvironment
Neoplasm Antigens
Cell- and Tissue-Based Therapy
Glioblastoma
Brain Neoplasms
Therapeutics
Neoplasms
Survival
Ubiquitin
Peptide Hydrolases
Immunotherapy
Therapeutics
Immunity

Research Output 1998 2019

1 Citation (Scopus)

A cycle involving HMGB1, IFN-γ and dendritic cells plays a putative role in anti-tumor immunity

Gao, Q., Li, F., Wang, S., Shen, Z., Cheng, S., Ping, Y., Qin, G., Chen, X., Yang, L., Cao, L., Liu, S., Zhang, B., Wang, L., Sun, Y. & Zhang, Y., Sep 1 2019, In : Cellular Immunology. 343, 103850.

Research output: Contribution to journalArticle

HMGB1 Protein
Dendritic Cells
Interferons
Immunity
Neoplasms
1 Citation (Scopus)
Open Access
Neoplasm Antibodies
Ligands
T-Lymphocytes
CD8 Antigens
Neoplasms
2 Citations (Scopus)

Cancer-cell-secreted CXCL11 promoted CD8 + T cells infiltration through docetaxel-induced-release of HMGB1 in NSCLC

Gao, Q., Wang, S., Chen, X., Cheng, S., Zhang, Z., Li, F., Huang, L., Yang, Y., Zhou, B., Yue, D., Wang, D., Cao, L., Maimela, N. R., Zhang, B., Yu, J., Wang, L. & Zhang, Y., Feb 11 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, 42.

Research output: Contribution to journalArticle

Open Access
docetaxel
HMGB1 Protein
T-Lymphocytes
Tumor Microenvironment
Neoplasms
2 Citations (Scopus)

CD73: An emerging checkpoint for cancer immunotherapy

Chen, S., Wainwright, D. A., Wu, J. D., Wan, Y., Matei, D. E., Zhang, Y. & Zhang, B., Jan 1 2019, In : Immunotherapy. 11, 11, p. 983-997 15 p.

Research output: Contribution to journalReview article

Immunotherapy
Neoplasms
Adenosine
Immunity
Carcinogenesis

CD73 expression on effector T cells sustained by TGF-b facilitates tumor resistance to anti-4-1BB/CD137 therapy

Chen, S., Fan, J., al, E. & Zhang, B., Jan 11 2019, In : Nature Communications. 10, p. 150 1 p.

Research output: Contribution to journalArticle