• 3158 Citations
1998 …2025

Research output per year

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Personal profile

Research Interests

Cancer immunology and immunotherapy. The Zhang laboratory functions as an integrated translational research program with the goal of designing and developing new immunotherapies and immunologic strategies for cancer treatment. The ongoing projects are focused on dissecting the molecular mechanisms used for tumor immune evasion based on the cutting-edge technical platforms.

Education/Academic qualification

PhD, Chinese Academy of Medical Science & Peking Union Medical College

… → 2003

MD, West China University

… → 1999

Research interests

  • Cancer Biology
  • Drug Discovery
  • Immune Regulation
  • Nanotechnology
  • Translational Research

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Grants

  • Research Output

    Interleukin-33-nuclear factor-κB-CCL2 signaling pathway promotes progression of esophageal squamous cell carcinoma by directing regulatory T cells

    Yue, Y., Lian, J., Wang, T., Luo, C., Yuan, Y., Qin, G., Zhang, B. & Zhang, Y., Mar 1 2020, In : Cancer Science. 111, 3, p. 795-806 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Metformin enhances the antitumor activity of CD8+ T Lymphocytes via the AMPK-miR-107-Eomes-PD-1 Pathway

    Zhang, Z., Li, F., Tian, Y., Cao, L., Gao, Q., Zhang, C., Zhang, K., Shen, C., Ping, Y., Maimela, N. R., Wang, L., Zhang, B. & Zhang, Y., May 1 2020, In : Journal of Immunology. 204, 9, p. 2575-2588 14 p.

    Research output: Contribution to journalArticle

  • Pembrolizumab in combination with the oncolytic virus pelareorep and chemotherapy in patients with advanced pancreatic adenocarcinoma: A phase Ib study a C

    Mahalingam, D., Wilkinson, G. A., Eng, K. H., Fields, P., Raber, P., Moseley, J. L., Cheetham, K., Coffey, M., Nuovo, G., Kalinski, P., Zhang, B., Arora, S. P. & Fountzilas, C., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 71-81 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations

    T Cell Dysfunction and Exhaustion in Cancer

    Zhang, Z., Liu, S., Zhang, B., Qiao, L., Zhang, Y. & Zhang, Y., Feb 11 2020, In : Frontiers in Cell and Developmental Biology. 8, 17.

    Research output: Contribution to journalReview article

    Open Access
  • A cycle involving HMGB1, IFN-γ and dendritic cells plays a putative role in anti-tumor immunity

    Gao, Q., Li, F., Wang, S., Shen, Z., Cheng, S., Ping, Y., Qin, G., Chen, X., Yang, L., Cao, L., Liu, S., Zhang, B., Wang, L., Sun, Y. & Zhang, Y., Sep 2019, In : Cellular Immunology. 343, 103850.

    Research output: Contribution to journalArticle

  • 2 Scopus citations