• 3297 Citations
19982020

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Article
2020

Interleukin-33-nuclear factor-κB-CCL2 signaling pathway promotes progression of esophageal squamous cell carcinoma by directing regulatory T cells

Yue, Y., Lian, J., Wang, T., Luo, C., Yuan, Y., Qin, G., Zhang, B. & Zhang, Y., Mar 1 2020, In : Cancer Science. 111, 3, p. 795-806 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Metformin enhances the antitumor activity of CD8+ T Lymphocytes via the AMPK-miR-107-Eomes-PD-1 Pathway

Zhang, Z., Li, F., Tian, Y., Cao, L., Gao, Q., Zhang, C., Zhang, K., Shen, C., Ping, Y., Maimela, N. R., Wang, L., Zhang, B. & Zhang, Y., May 1 2020, In : Journal of Immunology. 204, 9, p. 2575-2588 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

OX40+ plasmacytoid dendritic cells in the tumor microenvironment promote antitumor immunity

Poropatich, K., Dominguez, D., Chan, W. C., Andrade, J., Zha, Y., Wray, B., Miska, J. M., Qin, L., Cole, L., Coates, S., Patel, U., Samant, S. & Zhang, B., Jul 1 2020, In : The Journal of clinical investigation. 130, 7, p. 3528-3542 15 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Pembrolizumab in combination with the oncolytic virus pelareorep and chemotherapy in patients with advanced pancreatic adenocarcinoma: A phase Ib study a C

Mahalingam, D., Wilkinson, G. A., Eng, K. H., Fields, P., Raber, P., Moseley, J. L., Cheetham, K., Coffey, M., Nuovo, G., Kalinski, P., Zhang, B., Arora, S. P. & Fountzilas, C., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 71-81 11 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2019

A cycle involving HMGB1, IFN-γ and dendritic cells plays a putative role in anti-tumor immunity

Gao, Q., Li, F., Wang, S., Shen, Z., Cheng, S., Ping, Y., Qin, G., Chen, X., Yang, L., Cao, L., Liu, S., Zhang, B., Wang, L., Sun, Y. & Zhang, Y., Sep 2019, In : Cellular Immunology. 343, 103850.

Research output: Contribution to journalArticle

4 Scopus citations

A novel strategy to block mitotic progression for targeted therapy

Chi, J. J., Li, H., Zhou, Z., Izquierdo-Ferrer, J., Xue, Y., Wavelet, C. M., Schiltz, G. E., Zhang, B., Cristofanilli, M., Lu, X., Bahar, I. & Wan, Y., Nov 2019, In : EBioMedicine. 49, p. 40-54 15 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
3 Scopus citations

Cancer-cell-secreted CXCL11 promoted CD8 + T cells infiltration through docetaxel-induced-release of HMGB1 in NSCLC

Gao, Q., Wang, S., Chen, X., Cheng, S., Zhang, Z., Li, F., Huang, L., Yang, Y., Zhou, B., Yue, D., Wang, D., Cao, L., Maimela, N. R., Zhang, B., Yu, J., Wang, L. & Zhang, Y., Feb 11 2019, In : Journal for immunotherapy of cancer. 7, 1, 42.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

CD73 expression on effector T cells sustained by TGF-b facilitates tumor resistance to anti-4-1BB/CD137 therapy

Chen, S., Fan, J., al, E. & Zhang, B., Jan 11 2019, In : Nature Communications. 10, p. 150 1 p.

Research output: Contribution to journalArticle

CD73 expression on effector T cells sustained by TGF-β facilitates tumor resistance to anti-4-1BB/CD137 therapy

Chen, S., Fan, J., Zhang, M., Qin, L., Dominguez, D., Long, A., Wang, G., Ma, R., Li, H., Zhang, Y., Fang, D., Sosman, J. & Zhang, B., Dec 1 2019, In : Nature communications. 10, 1, 150.

Research output: Contribution to journalArticle

17 Scopus citations

IL-10 derived from M2 macrophage promotes cancer stemness via JAK1/STAT1/NF-κB/Notch1 pathway in non-small cell lung cancer

Yang, L., Dong, Y., Li, Y., Wang, D., Liu, S., Wang, D., Gao, Q., Ji, S., Chen, X., Lei, Q., Jiang, W., Wang, L., Zhang, B., Yu, J. J. & Zhang, Y., Aug 15 2019, In : International Journal of Cancer. 145, 4, p. 1099-1110 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Low-dose IFNg induces tumor cell stemness in tumor microenvironment of non–small cell lung cancer

Song, M., Ping, Y., Zhang, K., Yang, L., Li, F., Zhang, C., Cheng, S., Yue, D., Maimela, N. R., Qu, J., Liu, S., Sun, T., Li, Z., Xia, J., Zhang, B., Wang, L. & Zhang, Y., Jan 1 2019, In : Cancer Research. 79, 14, p. 3737-3748 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Rational vaccinology with spherical nucleic acids

Wang, S., Qin, L., Yamankurt, G., Skakuj, K., Huang, Z., Chen, P. C., Dominguez, D., Lee, A., Zhang, B. & Mirkin, C. A., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10473-10481 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
Open Access
12 Scopus citations

The Discovery of Biomarkers in Cancer Immunotherapy

George, AP., Zhang, Y., Kuzel, T. & Zhang, B., 2019, In : Computational and Structural Biotechnology Journal. 17, p. 484 1 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function

Li, S., Bostick, J. W., Ye, J., Qiu, J., Zhang, B., Urban, J. F., Avram, D. & Zhou, L., Nov 20 2018, In : Immunity. 49, 5, p. 915-928.e5 1 p.

Research output: Contribution to journalArticle

24 Scopus citations

Conjugation Chemistry-Dependent T-Cell Activation with Spherical Nucleic Acids

Skakuj, K., Wang, S., Qin, L., Lee, A., Zhang, B. & Mirkin, C. A., Jan 31 2018, In : Journal of the American Chemical Society. 140, 4, p. 1227-1230 4 p.

Research output: Contribution to journalArticle

18 Scopus citations

Dual TGF-β and PD-1 blockade synergistically enhances MAGE-A3-specific CD8+ T cell response in esophageal squamous cell carcinoma

Chen, X., Wang, L., Li, P., Song, M., Qin, G., Gao, Q., Zhang, Z., Yue, D., Wang, D., Nan, S., Qi, Y., Li, F., Yang, L., Huang, L., Zhang, M., Zhang, B., Gao, Y. & Zhang, Y., Nov 15 2018, In : International Journal of Cancer. 143, 10, p. 2561-2574 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

IL-33 in Tumor Immunity: Nothing to Sneeze At

Dominguez, D., Zhang, Y. & Zhang, B., 2018, In : Critical reviews in immunology. 38, 6, p. 453-470 18 p.

Research output: Contribution to journalArticle

IL6 derived from cancer-associated fibroblasts promotes chemoresistance via CXCR7 in esophageal squamous cell carcinoma

Qiao, Y., Zhang, C., Li, A., Wang, D., Luo, Z., Ping, Y., Zhou, B., Liu, S., Li, H., Yue, D., Zhang, Z., Chen, X., Shen, Z., Lian, J., Li, Y., Wang, S., Li, F., Huang, L., Wang, L., Zhang, B. & 3 others, Yu, J., Qin, Z. & Zhang, Y., Feb 15 2018, In : Oncogene. 37, 7, p. 873-883 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Maelstrom directs myeloid-derived suppressor cells to promote esophageal squamous cell carcinoma progression via activation of the Akt1/RelA/IL8 signaling pathway

Li, P., Chen, X., Qin, G., Yue, D., Zhang, Z., Ping, Y., Wang, D., Zhao, X., Song, M., Zhao, Q., Li, J., Liu, S., Wang, D., Zhang, C., Lian, J., Cao, L., Li, F., Huang, L., Wang, L., Yang, L. & 4 others, Huang, J., Li, H., Zhang, B. & Zhang, Y., Oct 2018, In : Cancer Immunology Research. 6, 10, p. 1246-1259 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis

Qin, G., Lian, J., Huang, L., Zhao, Q., Liu, S., Zhang, Z., Chen, X., Yue, D., Li, L., Li, F., Wang, L., Umansky, V., Zhang, B., Yang, S. & Zhang, Y., Jul 3 2018, In : OncoImmunology. 7, 7, e1442167.

Research output: Contribution to journalArticle

14 Scopus citations

Metformin-induced reduction of CD39 and CD73 blocks myeloid-derived suppressor cell activity in patients with ovarian cancer

Li, L., Wang, L., Li, J., Fan, Z., Yang, L., Zhang, Z., Zhang, C., Yue, D., Qin, G., Zhang, T., Li, F., Chen, X., Ping, Y., Wang, D., Gao, Q., He, Q., Huang, L., Li, H., Huang, J., Zhao, X. & 7 others, Xue, W., Sun, Z., Lu, J., Yu, J. J., Zhao, J., Zhang, B. & Zhang, Y., Apr 1 2018, In : Cancer Research. 78, 7, p. 1779-1791 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

MRI-guided interventional natural killer cell delivery for liver tumor treatment

Su, Z., Wang, X., Zheng, L., Lyu, T., Figini, M., Wang, B., Procissi, D., Shangguan, J., Sun, C., Pan, L., Qin, L., Zhang, B., Velichko, Y., Salem, R., Yaghmai, V., Larson, A. C. & Zhang, Z., May 2018, In : Cancer medicine. 7, 5, p. 1860-1869 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells

Choi, J., Pease, D. R., Chen, S., Zhang, B. & Phee, H., Jun 1 2018, In : Immunology. 154, 2, p. 309-321 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

RNA-Based Immunostimulatory Liposomal Spherical Nucleic Acids as Potent TLR7/8 Modulators

Guan, C., Chernyak, N., Dominguez, D., Cole, L., Zhang, B. & Mirkin, C. A., Dec 6 2018, In : Small. 14, 49, 1803284.

Research output: Contribution to journalArticle

16 Scopus citations

Th17 cell-derived IL-17A promoted tumor progression via STAT3/NF-κB/Notch1 signaling in non-small cell lung cancer

Wang, R., Yang, L., Zhang, C., Wang, R., Zhang, Z., He, Q., Chen, X., Zhang, B., Qin, Z., Wang, L. & Zhang, Y., Nov 2 2018, In : OncoImmunology. 7, 11, e1461303.

Research output: Contribution to journalArticle

8 Scopus citations

The endoplasmic reticulum–resident E3 ubiquitin ligase Hrd1 controls a critical checkpoint in B cell development in mice

Yang, Y., Kong, S., Zhang, Y., Melo-Cardenas, J., Gao, B., Zhang, Y., Zhang, D. D., Zhang, B., Song, J., Thorp, E., Zhang, K., Zhang, J. & Fang, D., Aug 17 2018, In : Journal of Biological Chemistry. 293, 33, p. 12934-12944 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Type 2 innate lymphoid cells impede IL-33-mediated tumor suppression

Long, A., Dominguez, D., Qin, L., Chen, S., Fan, J., Zhang, M., Fang, D., Zhang, Y., Kuzel, T. M. & Zhang, B., Dec 1 2018, In : Journal of Immunology. 201, 11, p. 3456-3464 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2017

A comparison of morphologic and molecular features of BRAF, ALK, and NTRK1 fusion spitzoid neoplasms

Amin, S. M., Haugh, A. M., Lee, C. Y., Zhang, B., Bubley, J. A., Merkel, E. A., Verzì, A. E. & Gerami, P., Jan 1 2017, In : American Journal of Surgical Pathology. 41, 4, p. 491-498 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Cancer Immunotherapies: Are They as Effective in the Elderly?

Poropatich, K., Fontanarosa, J., Samant, S., Sosman, J. A. & Zhang, B., Aug 1 2017, In : Drugs and Aging. 34, 8, p. 567-581 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

CD39/CD73 upregulation on myeloid-derived suppressor cells via TGF-β-mTOR-HIF-1 signaling in patients with non-small cell lung cancer

Li, J., Wang, L., Chen, X., Li, L., Li, Y., Ping, Y., Huang, L., Yue, D., Zhang, Z., Wang, F., Li, F., Yang, L., Huang, J., Yang, S., Li, H., Zhao, X., Dong, W., Yan, Y., Zhao, S., Huang, B. & 2 others, Zhang, B. & Zhang, Y., Jun 3 2017, In : OncoImmunology. 6, 6, e1320011.

Research output: Contribution to journalArticle

53 Scopus citations

Comprehensive T-cell immunophenotyping and next-generation sequencing of human papillomavirus (HPV)-positive and HPV-negative head and neck squamous cell carcinomas

Poropatich, K., Fontanarosa, J., Swaminathan, S., Dittmann, D., Chen, S., Samant, S. & Zhang, B., Nov 2017, In : Journal of Pathology. 243, 3, p. 354-365 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Correlation between the high expression levels of cancer-germline genes with clinical characteristics in esophageal squamous cell carcinoma

Chen, X., Wang, L., Yue, D., Liu, J., Huang, L., Yang, L., Cao, L., Qin, G., Li, A., Wang, D., Wang, M., Qi, Y., Zhang, B., van der Bruggen, P. & Zhang, Y., Aug 1 2017, In : Histology and Histopathology. 32, 8, p. 793-803 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Exogenous IL-33 restores dendritic cell activation and maturation in established cancer

Dominguez, D., Ye, C., Geng, Z., Chen, S., Fan, J., Qin, L., Long, A., Wang, L., Zhang, Z., Zhang, Y., Fang, D., Kuzel, T. M. & Zhang, B., Feb 1 2017, In : Journal of Immunology. 198, 3, p. 1365-1375 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Expression and prognostic relevance of MAGE-A3 and MAGE-C2 in non-small cell lung cancer

Chen, X., Wang, L., Liu, J., Huang, L., Li, Y., Gao, Q., Shi, X., Li, J., Li, F., Zhang, Z., Zhao, S., Zhang, B., van Der Bruggen, P. & Zhang, Y., Mar 2017, In : Oncology Letters. 13, 3, p. 1609-1618 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Genotypic and phenotypic features of BAP1 cancer syndrome: A report of 8 new families and review of cases in the literature

Haugh, A. M., Njauw, C. N., Bubley, J. A., Verzì, A. E., Zhang, B., Kudalkar, E., VandenBoom, T., Walton, K., Swick, B. L., Kumar, R., Rana, H. Q., Cochrane, S., McCormick, S. R., Shea, C. R., Tsao, H. & Gerami, P., Oct 2017, In : JAMA dermatology. 153, 10, p. 999-1006 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

miR-29a-3p suppresses cell proliferation and migration by downregulating IGF1R in hepatocellular carcinoma

Wang, X., Liu, S., Cao, L., Zhang, T., Yue, D., Wang, L., Ping, Y., He, Q., Zhang, C., Wang, M., Chen, X., Gao, Q., Wang, D., Zhang, Z., Wang, F., Yang, L., Li, J., Huang, L., Zhang, B. & Zhang, Y., Oct 17 2017, In : Oncotarget. 8, 49, p. 86592-86603 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

WEE1 inhibition by MK1775 as a single-agent therapy inhibits ovarian cancer viability

Zhang, M., Dominguez, D., Chen, S., Fan, J., Qin, L., Long, A., Li, X., Zhang, Y., Shi, H. & Zhang, B., 2017, In : Oncology Letters. 14, 3, p. 3580-3586 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2016
24 Scopus citations

Dynamic changes in CD45RA-Foxp3high regulatory T-cells in chronic hepatitis C patients during antiviral therapy

Li, Z., Ping, Y., Yu, Z., Wang, M., Yue, D., Zhang, Z., Li, J., Zhang, B., Shi, X. & Zhang, Y., Apr 1 2016, In : International Journal of Infectious Diseases. 45, p. 5-12 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas

Kong, S., Yang, Y., Xu, Y., Wang, Y., Zhang, Y., Melo-Cardenas, J., Xu, X., Gao, B., Thorp, E. B., Zhang, D. D., Zhang, B., Song, J., Zhang, K., Zhang, J., Zhang, J., Li, H. & Fang, D., Sep 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 37, p. 10394-10399 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Exogenous IL-33 overcomes T cell tolerance in murine acute myeloid leukemia

Qin, L., Dominguez, D., Chen, S., Fan, J., Long, A., Zhang, M., Fang, D., Zhang, Y., Kuzel, T. M. & Zhang, B., 2016, In : Oncotarget. 7, 38, p. 61069-61080 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Impaired T cell function in malignant pleural effusion is caused by TGF-β derived predominantly from macrophages

Li, L., Yang, L., Wang, L., Wang, F., Zhang, Z., Li, J., Yue, D., Chen, X., Ping, Y., Huang, L., Zhang, B. & Zhang, Y., Nov 15 2016, In : International Journal of Cancer. 139, 10, p. 2261-2269 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Inhibition of SALL4 reduces tumorigenicity involving epithelial-mesenchymal transition via Wnt/β-catenin pathway in esophageal squamous cell carcinoma

He, J., Zhou, M., Chen, X., Yue, D., Yang, L., Qin, G., Zhang, Z., Gao, Q., Wang, D., Zhang, C., Huang, L., Wang, L., Zhang, B., Yu, J. & Zhang, Y., Jun 21 2016, In : Journal of Experimental and Clinical Cancer Research. 35, 1, 98.

Research output: Contribution to journalArticle

34 Scopus citations

Molecular basis of antibody binding to mucin glycopeptides in lung cancer

Qu, J., Yu, H., Li, F., Zhang, C., Trad, A., Brooks, C., Zhang, B., Gong, T., Guo, Z., Li, Y., Ragupathi, G., Lou, Y., Hwu, P., Huang, W. & Zhou, D., Feb 2016, In : International journal of oncology. 48, 2, p. 587-594 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Nonoverlapping Clinical and Mutational Patterns in Melanomas from the Female Genital Tract and Atypical Genital Nevi

Yélamos, O., Merkel, E. A., Sholl, L. M., Zhang, B., Amin, S. M., Lee, C. Y., Guitart, G. E., Yang, J., Wenzel, A. T., Bunick, C. G., Yazdan, P., Choi, J. & Gerami, P., Sep 1 2016, In : Journal of Investigative Dermatology. 136, 9, p. 1858-1865 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Targeting ornithine decarboxylase by α-difluoromethylornithine inhibits tumor growth by impairing myeloid-derived suppressor cells

Ye, C., Geng, Z., Dominguez, D., Chen, S., Fan, J., Qin, L., Long, A., Zhang, Y., Kuzel, T. M. & Zhang, B., Jan 15 2016, In : Journal of Immunology. 196, 2, p. 915-923 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity

Xu, Y., Zhao, F., Qiu, Q., Chen, K., Wei, J., Kong, Q., Gao, B., Melo-Cardenas, J., Zhang, B., Zhang, J., Song, J., Zhang, D. D., Zhang, J., Fan, Y., Li, H. & Fang, D., Jul 15 2016, In : Nature communications. 7, 12073.

Research output: Contribution to journalArticle

12 Scopus citations
2015

CD163+CD14+ macrophages, a potential immune biomarker for malignant pleural effusion

Wang, F., Yang, L., Gao, Q., Huang, L., Wang, L., Wang, J., Wang, S., Zhang, B. & Zhang, Y., Aug 28 2015, In : Cancer Immunology, Immunotherapy. 64, 8, p. 965-976 12 p.

Research output: Contribution to journalArticle

18 Scopus citations