Bo Hu

  • 2806 Citations
1990 …2023
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Personal profile

Research Interests

The primary goals of my research projects is to improve our understanding of the molecular mechanisms and signaling pathways of human cancer initiation, tumorigenesis, invasion, metastases and angiogenesis, and to develop novel approaches for anti-cancer therapies by targeting molecular pathways by which human tumors develop and progress. Our approaches include molecular, cellular biology, histology, tumor xenografts in cell culture and animals model systems of human brain tumors (in particular, glioblastomas).

Training Experience

1994Postdoctoral Fellowship, University of California, San Diego

Education/Academic qualification

PhD, Ohio State University

… → 1992


  • Angiogenesis
  • Brain Cancer / Nervous System Cancer
  • Cell Biology
  • Molecular Biology
  • Neuro-Oncology
  • Neurology

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  • 6 Similar Profiles
Glioma Medicine & Life Sciences
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Growth Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Cell Movement Medicine & Life Sciences

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Grants 2012 2023

Research Output 1990 2019

Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response

Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S-Y., Yang, K., Li, Y. & Feng, H., Apr 5 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 147.

Research output: Contribution to journalArticle

Open Access
Switch Genes
Stem Cells

MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy

Huang, T., Wan, X., Alvarez, A. A., James, C. D., Song, X., Yang, Y., Sastry, N., Nakano, I., Sulman, E. P., Hu, B. & Cheng, S-Y., Jun 3 2019, In : Autophagy. 15, 6, p. 1100-1111 12 p.

Research output: Contribution to journalArticle


Autophagy and hallmarks of cancer

Huang, T., Song, X., Yang, Y., Wan, X., Alvarez, A. A., Sastry, N., Feng, H., Hu, B. & Cheng, S-Y., Jan 1 2018, In : Critical Reviews in Oncogenesis. 23, 5-6, p. 247-267 21 p.

Research output: Contribution to journalArticle

Antineoplastic Agents
1 Citation (Scopus)

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma

Pangeni, R. P., Zhang, Z., Alvarez, A. A., Wan, X., Sastry, N., Lu, S., Shi, T., Huang, T., Lei, C. X., James, C. D., Kessler, J., Brennan, C. W., Nakano, I., Lu, X., Hu, B., Zhang, W. & Cheng, S-Y., Apr 3 2018, In : Epigenetics. 13, 4, p. 432-448 17 p.

Research output: Contribution to journalArticle

Stem Cells
6 Citations (Scopus)

TRIM59 promotes gliomagenesis by inhibiting tc45 dephosphorylation of STAT3

Sang, Y., Li, Y., Song, L., Alvarez, A. A., Zhang, W., Lv, D., Tang, J., Liu, F., Chang, Z., Hatakeyama, S., Hu, B., Cheng, S-Y. & Feng, H., Apr 1 2018, In : Cancer Research. 78, 7, p. 1792-1804 13 p.

Research output: Contribution to journalArticle

Non-Receptor Type 2 Protein Tyrosine Phosphatase