Grants per year
Personal profile
Research Interests
The primary goals of my research projects is to improve our understanding of the molecular mechanisms and signaling pathways of human cancer initiation, tumorigenesis, invasion, metastases and angiogenesis, and to develop novel approaches for anti-cancer therapies by targeting molecular pathways by which human tumors develop and progress. Our approaches include molecular, cellular biology, histology, tumor xenografts in cell culture and animals model systems of human brain tumors (in particular, glioblastomas).
Training Experience
| 1994 | Postdoctoral Fellowship, University of California, San Diego |
Education/Academic qualification
PhD, Ohio State University
… → 1992
Research interests
- Angiogenesis
- Brain Cancer / Nervous System Cancer
- Cell Biology
- Molecular Biology
- Neuro-Oncology
- Neurology
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Grants
Role of Protein Methylation in Cell Mitosis and Glioblastoma
Cheng, S., Hu, B. & James, C. D.
National Institute of Neurological Disorders and Stroke
4/15/20 → 12/31/24
Project: Research project
SPORE for Translational Approaches to Brain Cancer
Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Chandler, J. P., Cheng, S., Horbinski, C. M., Hu, B., James, C. D., Kumthekar, P. U., Leikin, R. G., Lesniak, M. S., Liu, B. P., Lukas, R. V., Platanias, L. C., Sachdev, S., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.
8/17/18 → 7/31/23
Project: Research project
Autophagy Regulation of Glioblastoma Tumorigenesis and Responses to Therapy
Cheng, S., Hu, B. & James, C. D.
National Institute of Neurological Disorders and Stroke
9/30/15 → 6/30/20
Project: Research project
Glioblastoma Phenotype Modulation Through miRNA Control of Wnt Signaling
Cheng, S., Hu, B. & James, C. D.
National Institute of Neurological Disorders and Stroke
9/1/15 → 5/31/20
Project: Research project
Research Output
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity
Sang, Y., Li, Y., Zhang, Y., Alvarez, A. A., Yu, B., Zhang, W., Hu, B., Cheng, S. Y. & Feng, H., Dec 1 2019, In : Nature communications. 10, 1, 4013.Research output: Contribution to journal › Article
Open Access
3
Scopus
citations
Correction to: Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response (Journal of Orthopaedic Surgery and Research (2019) 38 (147) DOI: 10.1186/s13046-019-1151-x)
Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S. Y., Yang, K., Li, Y. & Feng, H., Jul 16 2019, In : Journal of Orthopaedic Surgery and Research. 14, 1, 215.Research output: Contribution to journal › Comment/debate
Open Access
Correction to: Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response (Journal of Experimental and Clinical Cancer Research (2019) 38 (147) DOI: 10.1186/s13046-019-1151-x)
Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S. Y., Yang, K., Li, Y. & Feng, H., Jul 29 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 331.Research output: Contribution to journal › Comment/debate
Open Access
Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response
Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S. Y., Yang, K., Li, Y. & Feng, H., Apr 5 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 147.Research output: Contribution to journal › Article
Open Access
2
Scopus
citations
MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy
Huang, T., Wan, X., Alvarez, A. A., James, C. D., Song, X., Yang, Y., Sastry, N., Nakano, I., Sulman, E. P., Hu, B. & Cheng, S. Y., Jun 3 2019, In : Autophagy. 15, 6, p. 1100-1111 12 p.Research output: Contribution to journal › Article
12
Scopus
citations