Grants per year
Personal profile
Research Interests
The primary goals of my research projects is to improve our understanding of the molecular mechanisms and signaling pathways of human cancer initiation, tumorigenesis, invasion, metastases and angiogenesis, and to develop novel approaches for anti-cancer therapies by targeting molecular pathways by which human tumors develop and progress. Our approaches include molecular, cellular biology, histology, tumor xenografts in cell culture and animals model systems of human brain tumors (in particular, glioblastomas).
Training Experience
| 1994 | Postdoctoral Fellowship, University of California, San Diego |
Education/Academic qualification
PhD, Ohio State University
… → 1992
Research interests
- Angiogenesis
- Brain Cancer / Nervous System Cancer
- Cell Biology
- Molecular Biology
- Neuro-Oncology
- Neurology
Fingerprint Dive into the research topics where Bo Hu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 21 Similar Profiles
Glioma
Medicine & Life Sciences
Glioblastoma
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Angiopoietin-2
Medicine & Life Sciences
Stem Cells
Medicine & Life Sciences
Phosphorylation
Medicine & Life Sciences
Growth
Medicine & Life Sciences
Carcinogenesis
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2012 2023
SPORE for Translational Approaches to Brain Cancer
Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Chandler, J. P., Cheng, S., Horbinski, C. M., Hu, B., James, C. D., Kumthekar, P. U., Leikin, R. G., Lesniak, M. S., Liu, B. P., Lukas, R. V., Mirkin, C. A., Platanias, L. C., Sachdev, S., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.
8/17/18 → 7/31/23
Project: Research project
Brain Neoplasms
Glioblastoma
Therapeutics
Neoplasms
Survival
Autophagy Regulation of Glioblastoma Tumorigenesis and Responses to Therapy
Cheng, S., Hu, B. & James, C. D.
National Institute of Neurological Disorders and Stroke
9/30/15 → 6/30/20
Project: Research project
Autophagy
Glioblastoma
Carcinogenesis
Phosphorylation
temozolomide
Glioblastoma Phenotype Modulation Through miRNA Control of Wnt Signaling
Cheng, S., Hu, B. & James, C. D.
National Institute of Neurological Disorders and Stroke
9/1/15 → 5/31/20
Project: Research project
Glioblastoma
MicroRNAs
Glioma
Phenotype
Stem Cells
Research Output 1990 2019
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity
Sang, Y., Li, Y., Zhang, Y., Alvarez, A. A., Yu, B., Zhang, W., Hu, B., Cheng, S. Y. & Feng, H., Dec 1 2019, In : Nature communications. 10, 1, 4013.Research output: Contribution to journal › Article
Open Access
phosphorylation
Phosphorylation
Ubiquitination
Glioblastoma
Tumors
Correction to: Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response (Journal of Experimental and Clinical Cancer Research (2019) 38 (147) DOI: 10.1186/s13046-019-1151-x)
Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S. Y., Yang, K., Li, Y. & Feng, H., Jul 29 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 331.Research output: Contribution to journal › Comment/debate
Open Access
Glioma
Publications
Stem Cells
Radiation
Gene Expression
Correction to: Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response (Journal of Orthopaedic Surgery and Research (2019) 38 (147) DOI: 10.1186/s13046-019-1151-x)
Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S-Y., Yang, K., Li, Y. & Feng, H., Jul 16 2019, In : Journal of Orthopaedic Surgery and Research. 14, 1, 215.Research output: Contribution to journal › Comment/debate
Open Access
Glioma
Orthopedics
Publications
Stem Cells
Radiation
2
Citations
(Scopus)
Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response
Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S. Y., Yang, K., Li, Y. & Feng, H., Apr 5 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 147.Research output: Contribution to journal › Article
Open Access
Switch Genes
Glioma
Stem Cells
Radiation
Glioblastoma
6
Citations
(Scopus)
MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy
Huang, T., Wan, X., Alvarez, A. A., James, C. D., Song, X., Yang, Y., Sastry, N., Nakano, I., Sulman, E. P., Hu, B. & Cheng, S. Y., Jun 3 2019, In : Autophagy. 15, 6, p. 1100-1111 12 p.Research output: Contribution to journal › Article
Autophagy
Glioblastoma
MicroRNAs
temozolomide
Sirolimus