Bo Hu

  • 3183 Citations
1990 …2020

Research output per year

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Personal profile

Research Interests

The primary goals of my research projects is to improve our understanding of the molecular mechanisms and signaling pathways of human cancer initiation, tumorigenesis, invasion, metastases and angiogenesis, and to develop novel approaches for anti-cancer therapies by targeting molecular pathways by which human tumors develop and progress. Our approaches include molecular, cellular biology, histology, tumor xenografts in cell culture and animals model systems of human brain tumors (in particular, glioblastomas).

Training Experience

1994Postdoctoral Fellowship, University of California, San Diego

Education/Academic qualification

PhD, Ohio State University

… → 1992

Research interests

  • Angiogenesis
  • Brain Cancer / Nervous System Cancer
  • Cell Biology
  • Molecular Biology
  • Neuro-Oncology
  • Neurology

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Research Output

CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity

Sang, Y., Li, Y., Zhang, Y., Alvarez, A. A., Yu, B., Zhang, W., Hu, B., Cheng, S. Y. & Feng, H., Dec 1 2019, In : Nature communications. 10, 1, 4013.

Research output: Contribution to journalArticle

Open Access
  • 3 Scopus citations
    Open Access
  • Open Access
  • Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response

    Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S. Y., Yang, K., Li, Y. & Feng, H., Apr 5 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 147.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy

    Huang, T., Wan, X., Alvarez, A. A., James, C. D., Song, X., Yang, Y., Sastry, N., Nakano, I., Sulman, E. P., Hu, B. & Cheng, S. Y., Jun 3 2019, In : Autophagy. 15, 6, p. 1100-1111 12 p.

    Research output: Contribution to journalArticle

  • 12 Scopus citations