Bo Hu

  • 2860 Citations
1990 …2023
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Personal profile

Research Interests

The primary goals of my research projects is to improve our understanding of the molecular mechanisms and signaling pathways of human cancer initiation, tumorigenesis, invasion, metastases and angiogenesis, and to develop novel approaches for anti-cancer therapies by targeting molecular pathways by which human tumors develop and progress. Our approaches include molecular, cellular biology, histology, tumor xenografts in cell culture and animals model systems of human brain tumors (in particular, glioblastomas).

Training Experience

1994Postdoctoral Fellowship, University of California, San Diego

Education/Academic qualification

PhD, Ohio State University

… → 1992

Research interests

  • Angiogenesis
  • Brain Cancer / Nervous System Cancer
  • Cell Biology
  • Molecular Biology
  • Neuro-Oncology
  • Neurology

Fingerprint Dive into the research topics where Bo Hu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 26 Similar Profiles
Glioma Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Angiopoietin-2 Medicine & Life Sciences
Growth Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2012 2023

Research Output 1990 2019

Correction to: Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response (Journal of Orthopaedic Surgery and Research (2019) 38 (147) DOI: 10.1186/s13046-019-1151-x)

Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S-Y., Yang, K., Li, Y. & Feng, H., Jul 16 2019, In : Journal of Orthopaedic Surgery and Research. 14, 1, 215.

Research output: Contribution to journalComment/debate

Open Access
Glioma
Orthopedics
Publications
Stem Cells
Radiation

Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response

Wang, Y., Hou, Y., Zhang, W., Alvarez, A. A., Bai, Y., Hu, B., Cheng, S-Y., Yang, K., Li, Y. & Feng, H., Apr 5 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 147.

Research output: Contribution to journalArticle

Open Access
Switch Genes
Glioma
Stem Cells
Radiation
Glioblastoma

MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy

Huang, T., Wan, X., Alvarez, A. A., James, C. D., Song, X., Yang, Y., Sastry, N., Nakano, I., Sulman, E. P., Hu, B. & Cheng, S-Y., Jun 3 2019, In : Autophagy. 15, 6, p. 1100-1111 12 p.

Research output: Contribution to journalArticle

Autophagy
Glioblastoma
MicroRNAs
temozolomide
Sirolimus

Autophagy and hallmarks of cancer

Huang, T., Song, X., Yang, Y., Wan, X., Alvarez, A. A., Sastry, N., Feng, H., Hu, B. & Cheng, S-Y., Jan 1 2018, In : Critical Reviews in Oncogenesis. 23, 5-6, p. 247-267 21 p.

Research output: Contribution to journalArticle

Autophagy
Neoplasms
Lysosomes
Organelles
Antineoplastic Agents
3 Citations (Scopus)

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma

Pangeni, R. P., Zhang, Z., Alvarez, A. A., Wan, X., Sastry, N., Lu, S., Shi, T., Huang, T., Lei, C. X., James, C. D., Kessler, J., Brennan, C. W., Nakano, I., Lu, X., Hu, B., Zhang, W. & Cheng, S-Y., Apr 3 2018, In : Epigenetics. 13, 4, p. 432-448 17 p.

Research output: Contribution to journalArticle

Glioblastoma
Epigenomics
Glioma
Stem Cells
Genome