Grants per year
Personal profile
Research Interests
The primary goals of my research projects is to improve our understanding of the molecular mechanisms and signaling pathways of human cancer initiation, tumorigenesis, invasion, metastases and angiogenesis, and to develop novel approaches for anti-cancer therapies by targeting molecular pathways by which human tumors develop and progress. Our approaches include molecular, cellular biology, histology, tumor xenografts in cell culture and animals model systems of human brain tumors (in particular, glioblastomas).
Training Experience
| 1994 | Postdoctoral Fellowship, University of California, San Diego |
Expertise related to UN Sustainable Devlopment Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Ohio State University
… → 1992
Research interests
- Angiogenesis
- Brain Cancer / Nervous System Cancer
- Cell Biology
- Molecular Biology
- Neuro-Oncology
- Neurology
Fingerprint
Dive into the research topics where Bo Hu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Role of Protein Methylation in Cell Mitosis and Glioblastoma
Cheng, S., Hu, B. & James, C. D.
National Institute of Neurological Disorders and Stroke
4/15/20 → 12/31/24
Project: Research project
-
SPORE for Translational Approaches to Brain Cancer
Lesniak, M. S., Chandler, J. P., Hu, B., Kumthekar, P. U., Leikin, R. G., Liu, B. P., Sachdev, S., Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Cheng, S., Horbinski, C. M., James, C. D., Lukas, R. V., Platanias, L. C., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.
8/17/18 → 7/31/23
Project: Research project
-
-
Autophagy Regulation of Glioblastoma Tumorigenesis and Responses to Therapy
Cheng, S., Hu, B. & James, C. D.
National Institute of Neurological Disorders and Stroke
9/30/15 → 6/30/21
Project: Research project
-
Glioblastoma Phenotype Modulation Through miRNA Control of Wnt Signaling
Cheng, S., Hu, B. & James, C. D.
National Institute of Neurological Disorders and Stroke
9/1/15 → 5/31/21
Project: Research project
-
PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
Huang, T., Yang, Y., Song, X., Wan, X., Wu, B., Sastry, N., Horbinski, C. M., Zeng, C., Tiek, D., Goenka, A., Liu, F., Brennan, C. W., Kessler, J. A., Stupp, R., Nakano, I., Sulman, E. P., Nishikawa, R., James, C. D., Zhang, W., Xu, W. & 2 others, , Mar 18 2021, In: Molecular cell. 81, 6, p. 1276-1291.e9Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
The Many Facets of Therapy Resistance and Tumor Recurrence in Glioblastoma
Goenka, A., Tiek, D., Song, X., Huang, T., Hu, B. & Cheng, S. Y., Feb 24 2021, In: Cells. 10, 3Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
LY6K promotes glioblastoma tumorigenicity via CAV-1–mediated ERK1/2 signaling enhancement
Sastry, N. G., Wan, X., Huang, T., Alvarez, A. A., Pangeni, R. P., Song, X., James, C. D., Horbinski, C. M., Brennan, C. W., Nakano, I., Hu, B. & Cheng, S. Y., Sep 1 2020, In: Neuro-oncology. 22, 9, p. 1315-1326 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Stem cell programs in cancer initiation, progression, and therapy resistance
Huang, T., Song, X., Xu, D., Tiek, D., Goenka, A., Wu, B., Sastry, N., Hu, B. & Cheng, S. Y., 2020, In: Theranostics. 10, 19, p. 8721-8743 23 p.Research output: Contribution to journal › Review article › peer-review
Open Access17 Scopus citations -
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity
Sang, Y., Li, Y., Zhang, Y., Alvarez, A. A., Yu, B., Zhang, W., Hu, B., Cheng, S. Y. & Feng, H., Dec 1 2019, In: Nature communications. 10, 1, 4013.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations