Bo Hu

  • 2965 Citations
1990 …2023
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1990 2019

Filter
Article
1990
2 Citations (Scopus)

Isolated myocytes from a normal human heart.

Hohl, C. M., Hu, B., Wimsatt, D. K., Fertel, R. H., Starling, R. C., Brierley, G. P. & Altschuld, R. A., Jan 1 1990, In : Progress in Clinical and Biological Research. 327, p. 735-742 8 p.

Research output: Contribution to journalArticle

Cell Separation
Glycolysis
Cyclic AMP
Muscle Cells
Myocardium
1991
7 Citations (Scopus)

Phorbol esters and cyclic AMP activate AMP deaminase in adult rat cardiac myocytes

Hu, B., Altschuld, R. A. & Hohl, C. M., Nov 15 1991, In : Archives of biochemistry and biophysics. 291, 1, p. 100-106 7 p.

Research output: Contribution to journalArticle

AMP Deaminase
Phorbol Esters
Inosine Monophosphate
Cardiac Myocytes
Cyclic AMP
1993
8 Citations (Scopus)

Adenosine stimulation of AMP deaminase activity in adult-rat cardiac myocytes

Hu, B., Altschuld, R. A. & Hohl, C. M., Jan 1 1993, In : American Journal of Physiology - Cell Physiology. 264, 1 33-1

Research output: Contribution to journalArticle

AMP Deaminase
Cardiac Myocytes
Adenosine
Rats
Inosine Monophosphate
31 Citations (Scopus)

Effects of obesity and hypertension on ventricular myocytes: Comparison of cells from adult SHHF/MCC-cp and JCR:LA-cp rats

Hohl, C. M., Hu, B., Fertel, R. H., Russell, J. C., Mccune, S. A. & Altschuld, R. A., Jan 1 1993, In : Cardiovascular research. 27, 2, p. 238-242 5 p.

Research output: Contribution to journalArticle

Muscle Cells
Isoproterenol
Obesity
Hypertension
Sarcoplasmic Reticulum

Effects of obesity and hypertension on ventricular myocytes: Comparison of cells from adult SHHF/Mcc-cp and JCR:LA-cp RATS

Hohl, C. M., Hu, B., Fertel, R. H., Russell, J. C., Mccune, S. A. & Altschuld, R. A., Jan 1 1993, In : Cardiovascular Research. 27, 2, p. 238-242 5 p.

Research output: Contribution to journalArticle

Muscle Cells
Isoproterenol
Obesity
Hypertension
Sarcoplasmic Reticulum
1995
45 Citations (Scopus)

Isolation and molecular cloning of a novel bone phosphoprotein related in sequence to the cystatin family of thiol protease inhibitors

Hu, B., Coulson, L., Moyer, B. & Price, P. A., Jan 1 1995, In : Journal of Biological Chemistry. 270, 1, p. 431-436 6 p.

Research output: Contribution to journalArticle

Cystatins
Cloning
Phosphoproteins
Molecular Cloning
Protease Inhibitors
1996
161 Citations (Scopus)

Isolation and sequence of a novel human chondrocyte protein related to mammalian members of the chitinase protein family

Hu, B., Trinh, K., Figueira, W. F. & Price, P. A., Aug 27 1996, In : Journal of Biological Chemistry. 271, 32, p. 19415-19420 6 p.

Research output: Contribution to journalArticle

Chitinases
Chondrocytes
Macrophages
Conditioned Culture Medium
Glycoproteins
1997
27 Citations (Scopus)

Effect of cell density and growth factors on matrix GLA protein expression by normal rat kidney cells

Cancela, M. L., Hu, B. & Price, P. A., May 1 1997, In : Journal of Cellular Physiology. 171, 2, p. 125-134 10 p.

Research output: Contribution to journalArticle

Rats
Intercellular Signaling Peptides and Proteins
Cell Count
Kidney
Vitamin K
2003
118 Citations (Scopus)

Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2

Hu, B., Guo, P., Fang, Q., Tao, H. Q., Wang, D., Nagane, M., Huang, H. J. S., Gunji, Y., Nishikawa, R., Alitalo, K., Cavenee, W. K. & Cheng, S. Y., Jul 22 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 15, p. 8904-8909 6 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Metalloproteases
Glioma
Neoplasms
Brain
48 Citations (Scopus)

A nuclear target for interleukin-1α: Interaction with the growth suppressor necdin modulates proliferation and collagen expression

Hu, B., Wang, S., Zhang, Y., Feghali, C. A., Dingman, J. R. & Wright, T. M., Aug 19 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 17, p. 10008-10013 6 p.

Research output: Contribution to journalArticle

Interleukin-1
Collagen
Growth
Fibroblasts
Systemic Scleroderma
56 Citations (Scopus)

Overexpression of vascular endothelial growth factor by MCF-7 breast cancer cells promotes estrogen-independent tumor growth in vivo

Guo, P., Fang, Q., Tao, H. Q., Schafer, C. A., Fenton, B. M., Ding, I., Hu, B. & Cheng, S. Y., Aug 1 2003, In : Cancer Research. 63, 15, p. 4684-4691 8 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Estrogens
Breast Neoplasms
Growth
Neoplasms
246 Citations (Scopus)

Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment

Guo, P., Hu, B., Gu, W., Xu, L., Wang, D., Huang, H. J. S., Cavenee, W. K. & Cheng, S. Y., Apr 1 2003, In : American Journal of Pathology. 162, 4, p. 1083-1093 11 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-sis
Pericytes
Glioma
Vascular Endothelial Growth Factor A
Endothelium
2004
51 Citations (Scopus)

Identification of two novel alternatively spliced Neuropilin-1 isoforms

Cackowski, F. C., Xu, L., Hu, B. & Cheng, S. Y., Jul 1 2004, In : Genomics. 84, 1, p. 82-94 13 p.

Research output: Contribution to journalArticle

Neuropilin-1
Protein Isoforms
Cell Movement
Semaphorin-3A
Semaphorins
13 Citations (Scopus)

Overexpression of VEGF121, but not VEGF165 or FGF-1, improves oxygenation in MCF-7 breast tumours

Fenton, B. M., Paoni, S. F., Liu, W., Cheng, S. Y., Hu, B. & Ding, I., Jan 26 2004, In : British Journal of Cancer. 90, 2, p. 430-435 6 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Vascular Endothelial Growth Factor A
Breast Neoplasms
Angiogenesis Inhibitors
Protein Isoforms
2005
91 Citations (Scopus)

Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 γ 2 correlates with the invasiveness of human glioma

Quo, P., Imanishi, Y., Cackowski, F. C., Jarzynka, M. J., Tao, H. Q., Nishikawa, R., Hirose, T., Hu, B. & Cheng, S. Y., Jan 1 2005, In : American Journal of Pathology. 166, 3, p. 877-890 14 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Metalloproteases
Glioma
Up-Regulation
Membranes
2006
123 Citations (Scopus)

Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the αvβ1 integrin and focal adhesion kinase signaling pathway

Hu, B., Jarzynka, M. J., Guo, P., Imanishi, Y., Schlaepfer, D. D. & Cheng, S. Y., Jan 15 2006, In : Cancer Research. 66, 2, p. 775-783 9 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Focal Adhesion Protein-Tyrosine Kinases
Metalloproteases
Integrins
Glioma
46 Citations (Scopus)

Estradiol and nicotine exposure enhances A549 bronchioloalveolar carcinoma xenograft growth in mice through the stimulation of angiogenesis

Jarzynka, M. J., Gou, P., Bar-Joseph, I., Hu, B. & Cheng, S. Y., Feb 1 2006, In : International Journal of Oncology. 28, 2, p. 337-344 8 p.

Research output: Contribution to journalArticle

Bronchiolo-Alveolar Adenocarcinoma
Nicotine
Heterografts
Estradiol
Vascular Endothelial Growth Factor A
2007
131 Citations (Scopus)

Angiopoietin-2 stimulates breast cancer metastasis through the α5β1 integrin-mediated pathway

Imanishi, Y., Hu, B., Jarzynka, M. J., Guo, P., Elishaev, E., Bar-Joseph, I. & Cheng, S. Y., May 1 2007, In : Cancer Research. 67, 9, p. 4254-4263 10 p.

Research output: Contribution to journalArticle

Angiopoietin-2
Integrins
Breast Neoplasms
Neoplasm Metastasis
Cadherins
99 Citations (Scopus)

ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion

Jarzynka, M. J., Hu, B., Hui, K. M., Bar-Joseph, I., Gu, W., Hirose, T., Haney, L. B., Ravichandran, K. S., Nishikawa, R. & Cheng, S. Y., Aug 1 2007, In : Cancer Research. 67, 15, p. 7203-7211 9 p.

Research output: Contribution to journalArticle

Guanine Nucleotide Exchange Factors
Glioma
Cell Movement
Neoplasms
Brain
130 Citations (Scopus)

Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway

Hu, B., Guo, P., Bar-Joseph, I., Imanishi, Y., Jarzynka, M. J., Bogler, O., Mikkelsen, T., Hirose, T., Nishikawa, R. & Cheng, S. Y., Aug 16 2007, In : Oncogene. 26, 38, p. 5577-5586 10 p.

Research output: Contribution to journalArticle

Neuropilin-1
Hepatocyte Growth Factor
Glioma
Neoplasms
Cell Survival
2009
68 Citations (Scopus)

ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway

Hu, B., Shi, B., Jarzynka, M. J., Yiin, J. J., D'Souza-Schorey, C. & Cheng, S. Y., Feb 1 2009, In : Cancer Research. 69, 3, p. 794-801 8 p.

Research output: Contribution to journalArticle

GTPase-Activating Proteins
Glioma
Cell Movement
Monomeric GTP-Binding Proteins
ADP-ribosylation factor 6
12 Citations (Scopus)

Comparable ecological dynamics underlie early cancer invasion and species dispersal, involving self-organizing processes

Marco, D. E., Cannas, S. A., Montemurro, M. A., Hu, B. & Cheng, S. Y., Jan 7 2009, In : Journal of Theoretical Biology. 256, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

species dispersal
Invasion
Self-organizing
Fractals
Tumors
66 Citations (Scopus)

Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity

Yiin, J. J., Hu, B., Jarzynka, M. J., Feng, H., Liu, K. W., Wu, J. Y., Ma, H. I. & Cheng, S. Y., Jan 1 2009, In : Neuro-oncology. 11, 6, p. 779-789 11 p.

Research output: Contribution to journalArticle

Glioma
Brain
Cell Movement
Catenins
Cadherins
2010
29 Citations (Scopus)

ZD6474, a multitargeted inhibitor for receptor tyrosine kinases, suppresses growth of gliomas expressing an epidermal growth factor receptor mutant, EGFRvIII, in the brain

Yiin, J. J., Hu, B., Schornack, P. A., Sengar, R. S., Liu, K. W., Feng, H., Lieberman, F. S., Chiou, S. H., Sarkaria, J. N., Wiener, E. C., Ma, H. I. & Cheng, S. Y., Apr 1 2010, In : Molecular cancer therapeutics. 9, 4, p. 929-941 13 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Glioma
Brain
Growth
2011
73 Citations (Scopus)

Activation of Rac1 by Src-dependent phosphorylation of Dock180 Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans

Feng, H., Hu, B., Liu, K. W., Li, Y., Lu, X., Cheng, T., Yiin, J. J., Lu, S., Keezer, S., Fenton, T., Furnari, F. B., Hamilton, R. L., Vuori, K., Sarkaria, J. N., Nagane, M., Nishikawa, R., Cavenee, W. K. & Cheng, S. Y., Dec 1 2011, In : Journal of Clinical Investigation. 121, 12, p. 4670-4684 15 p.

Research output: Contribution to journalArticle

Glioma
Tyrosine
Carcinogenesis
Phosphorylation
Glioblastoma
27 Citations (Scopus)
Angiopoietin-2
B-Cell Lymphoma
Cells
Breast Neoplasms
Neoplasm Metastasis
50 Citations (Scopus)

SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans

Liu, K. W., Feng, H., Bachoo, R., Kazlauskas, A., Smith, E. M., Symes, K., Hamilton, R. L., Nagane, M., Nishikawa, R., Hu, B. & Cheng, S. Y., Mar 1 2011, In : Journal of Clinical Investigation. 121, 3, p. 905-917 13 p.

Research output: Contribution to journalArticle

Glioblastoma
Phosphatidylinositol 3-Kinases
Carcinogenesis
Glioma
Cyclin-Dependent Kinase Inhibitor p16
2012
46 Citations (Scopus)

Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion

Feng, H., Liu, K. W., Guo, P., Zhang, P., Cheng, T., McNiven, M. A., Johnson, G. R., Hu, B. & Cheng, S. Y., May 1 2012, In : Oncogene. 31, 21, p. 2691-2702 12 p.

Research output: Contribution to journalArticle

Dynamin II
Platelet-Derived Growth Factor Receptors
Glioblastoma
Glioma
Growth
47 Citations (Scopus)

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis

Feng, H., Hu, B., Jarzynka, M. J., Li, Y., Keezer, S., Johns, T. G., Tang, C. K., Hamilton, R. L., Vuori, K., Nishikawa, R., Sarkaria, J. N., Fenton, T., Cheng, T., Furnari, F. B., Cavenee, W. K. & Cheng, S. Y., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 3018-3023 6 p.

Research output: Contribution to journalArticle

Cytokinesis
src-Family Kinases
Glioblastoma
Tyrosine
Carcinogenesis
110 Citations (Scopus)

TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets

Song, L., Liu, L., Wu, Z., Li, Y., Ying, Z., Lin, C., Wu, J., Hu, B., Cheng, S-Y., Li, M. & Li, J., Oct 1 2012, In : Journal of Clinical Investigation. 122, 10, p. 3563-3578 16 p.

Research output: Contribution to journalArticle

Glioma
Ubiquitin
Neoplasms
Phenotype
2013
33 Citations (Scopus)

Bmi-1 Promotes Glioma Angiogenesis by Activating NF-κB Signaling

Jiang, L., Song, L., Wu, J., Yang, Y., Zhu, X., Hu, B., Cheng, S-Y. & Li, M., Jan 31 2013, In : PloS one. 8, 1, e55527.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor C
angiogenesis
Glioma
Endothelial cells
vascular endothelial growth factor C
29 Citations (Scopus)

Downregulation of miR-452 promotes stem-like traits and tumorigenicity of gliomas

Liu, L., Chen, K., Wu, J., Shi, L., Hu, B., Cheng, S-Y., Li, M. & Song, L., Jul 1 2013, In : Clinical Cancer Research. 19, 13, p. 3429-3438 10 p.

Research output: Contribution to journalArticle

Glioma
Down-Regulation
Carcinogenesis
Neural Crest
Genetic Promoter Regions
110 Citations (Scopus)

Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype

Ying, Z., Li, Y., Wu, J., Zhu, X., Yang, Y., Tian, H., Li, W., Hu, B., Cheng, S. Y. & Li, M., Jan 15 2013, In : Cancer Research. 73, 2, p. 990-999 10 p.

Research output: Contribution to journalArticle

Glioma
Stem Cells
Phenotype
Neural Stem Cells
Cell Movement
272 Citations (Scopus)

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3

Mao, P., Joshi, K., Li, J., Kim, S. H., Li, P., Santana-Santos, L., Luthra, S., Chandran, U. R., Benos, P. V., Smith, L., Wang, M., Hu, B., Cheng, S. Y., Sobol, R. W. & Nakano, I., May 21 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 21, p. 8644-8649 6 p.

Research output: Contribution to journalArticle

Aldehyde Dehydrogenase
Mesenchymal Stromal Cells
Glioma
Stem Cells
Radiation
57 Citations (Scopus)

MiR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops

Song, L., Lin, C., Gong, H., Wang, C., Liu, L., Wu, J., Tao, S., Hu, B., Cheng, S-Y., Li, M. & Li, J., Feb 1 2013, In : Cell Research. 23, 2, p. 274-289 16 p.

Research output: Contribution to journalArticle

Glioma
Ubiquitin
Epigenomics
Neoplasms
Up-Regulation
28 Citations (Scopus)

YM-155 potentiates the effect of ABT-737 in malignant humanglioma cells via survivin and Mcl-1 downregulation in an EGFR-dependent context

Jane, E. P., Premkumar, D. R., DiDomenico, J. D., Hu, B., Cheng, S-Y. & Pollack, I. F., Mar 1 2013, In : Molecular cancer therapeutics. 12, 3, p. 326-338 13 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Down-Regulation
Glioma
Apoptosis
Inhibitory Concentration 50
2014
36 Citations (Scopus)

EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis

Feng, H., Lopez, G. Y., Kim, C. K., Alvarez, A., Duncan, C. G., Nishikawa, R., Nagane, M., Su, A. J. A., Auron, P. E., Hedberg, M. L., Wang, L., Raizer, J. J., Kessler, J. A., Parsa, A. T., Gao, W. Q., Kim, S. H., Minata, M., Nakano, I., Grandis, J. R., McLendon, R. E. & 7 others, Bigner, D. D., Lin, H. K., Furnari, F. B., Cavenee, W. K., Hu, B., Yan, H. & Cheng, S. Y., Sep 2 2014, In : Journal of Clinical Investigation. 124, 9, p. 3741-3756 16 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 6
Carcinogenesis
Phosphorylation
Head and Neck Neoplasms
Neuropilins
42 Citations (Scopus)

EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180

Feng, H., Hu, B., Vuori, K., Sarkaria, J. N., Furnari, F. B., Cavenee, W. K. & Cheng, S. Y., May 8 2014, In : Oncogene. 33, 19, p. 2504-2512 9 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Glioma
Serine
Phosphorylation
Growth
2015
15 Citations (Scopus)

Gene expression profiling distinguishes proneural glioma stem cells from mesenchymal glioma stem cells

Chandran, U. R., Luthra, S., Santana-Santos, L., Mao, P., Kim, S. H., Minata, M., Li, J., Benos, P. V., DeWang, M., Hu, B., Cheng, S-Y., Nakano, I. & Sobol, R. W., Sep 1 2015, In : Genomics Data. 5, p. 333-336 4 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
Stem cells
Mesenchymal Stromal Cells
Gene expression
Glioma
10 Citations (Scopus)

Identifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive Sets

Lu, S., Lu, K. N., Cheng, S-Y., Hu, B., Ma, X., Nystrom, N. & Lu, X., Aug 1 2015, In : PLoS computational biology. 11, 8, e1004257.

Research output: Contribution to journalArticle

Mutually exclusive
Genomics
Driver
cancer
Cancer
7 Citations (Scopus)

Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α

Feng, H., Li, Y., Yin, Y., Zhang, W., Hou, Y., Zhang, L., Li, Z., Xie, B., Gao, W. Q., Sarkaria, J. N., Raizer, J. J., James, C. D., Parsa, A. T., Hu, B. & Cheng, S-Y., Jan 1 2015, In : Neuro-oncology. 17, 6, p. 832-842 11 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Cyclic AMP-Dependent Protein Kinases
Glioma
Serine
Phosphorylation
2016
25 Citations (Scopus)

A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways

Huang, T., Alvarez, A. A., Pangeni, R. P., Horbinski, C. M., Lu, S., Kim, S. H., James, C. D., Raizer, J. J., Kessler, J. A., Brenann, C. W., Sulman, E. P., Finocchiaro, G., Tan, M., Nishikawa, R., Lu, X., Nakano, I., Hu, B. & Cheng, S. Y., Oct 4 2016, In : Nature communications. 7, 12885.

Research output: Contribution to journalArticle

phenotype
Glioblastoma
regulators
Phenotype
Networks (circuits)
8 Citations (Scopus)

A simple, low-cost staining method for rapid-throughput analysis of tumor spheroids

Eckerdt, F., Alvarez, A., Bell, J., Arvanitis, C., Iqbal, A., Arslan, A. D., Hu, B., Cheng, S. Y., Goldman, S. & Platanias, L. C., Jan 1 2016, In : BioTechniques. 60, 1, p. 43-46 4 p.

Research output: Contribution to journalArticle

Tumors
Neoplastic Stem Cells
Throughput
Staining and Labeling
Stem cells
50 Citations (Scopus)

SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans

Zhang, L., Zhang, W., Li, Y., Alvarez, A. A., Li, Z., Wang, Y., Song, L., Lv, D., Nakano, I., Hu, B., Cheng, S-Y. & Feng, H., Oct 27 2016, In : Oncogene. 35, 43, p. 5641-5652 12 p.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Epithelial-Mesenchymal Transition
Glioma
1-Phosphatidylinositol 4-Kinase
Stem Cells
2017
13 Citations (Scopus)

Histone acetyltransferase KAT6A upregulates PI3K/AKT signaling through TRIM24 binding

Lv, D., Jia, F., Hou, Y., Sang, Y., Alvarez, A. A., Zhang, W., Gao, W. Q., Hu, B., Cheng, S-Y., Ge, J., Li, Y. & Feng, H., Nov 15 2017, In : Cancer Research. 77, 22, p. 6190-6201 12 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Glioblastoma
Phosphatidylinositol 3-Kinases
Up-Regulation
Histone Code
12 Citations (Scopus)

Internalized CD44s splice isoform attenuates EGFR degradation by targeting Rab7A

Wang, W., Zhang, H., Liu, S., Kim, C. K., Xu, Y., Hurley, L. A., Nishikawa, R., Nagane, M., Hu, B., Stegh, A. H., Cheng, S. Y. & Cheng, C., Aug 1 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 31, p. 8366-8371 6 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Protein Isoforms
Lysosomes
Monomeric GTP-Binding Proteins
Endosomes
37 Citations (Scopus)

MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

Huang, T., Kim, C. K., Alvarez, A. A., Pangeni, R. P., Wan, X., Song, X., Shi, T., Yang, Y., Sastry, N., Horbinski, C. M., Lu, S., Stupp, R., Kessler, J. A., Nishikawa, R., Nakano, I., Sulman, E. P., Lu, X., James, C. D., Yin, X. M., Hu, B. & 1 others, Cheng, S. Y., Dec 11 2017, In : Cancer Cell. 32, 6, p. 840-855.e8

Research output: Contribution to journalArticle

Autophagy
Glioblastoma
Phosphorylation
Radiotherapy
Serine
19 Citations (Scopus)

TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma

Lv, D., Li, Y., Zhang, W., Alvarez, A. A., Song, L., Tang, J., Gao, W. Q., Hu, B., Cheng, S-Y. & Feng, H., Dec 1 2017, In : Nature communications. 8, 1, 1454.

Research output: Contribution to journalArticle

Glioblastoma
Epidermal Growth Factor Receptor
Glioma
Carcinogenesis
Chemical activation
2018

Autophagy and hallmarks of cancer

Huang, T., Song, X., Yang, Y., Wan, X., Alvarez, A. A., Sastry, N., Feng, H., Hu, B. & Cheng, S-Y., Jan 1 2018, In : Critical Reviews in Oncogenesis. 23, 5-6, p. 247-267 21 p.

Research output: Contribution to journalArticle

Autophagy
Neoplasms
Lysosomes
Organelles
Antineoplastic Agents
5 Citations (Scopus)

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma

Pangeni, R. P., Zhang, Z., Alvarez, A. A., Wan, X., Sastry, N., Lu, S., Shi, T., Huang, T., Lei, C. X., James, C. D., Kessler, J., Brennan, C. W., Nakano, I., Lu, X., Hu, B., Zhang, W. & Cheng, S-Y., Apr 3 2018, In : Epigenetics. 13, 4, p. 432-448 17 p.

Research output: Contribution to journalArticle

Glioblastoma
Epigenomics
Glioma
Stem Cells
Genome