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Bria Coates

  • 361 Citations
20052019

Research output per year

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Personal profile

Research Interests

I am a physician-scientist who specializes in pediatric critical care medicine. I received my MD from the University of Washington and completed my Residency in Pediatrics and Fellowship in Critical Care Medicine at Northwestern University. I joined the faculty in the Pediatric Critical Care Division in 2011.

My research explores differences in the inflammatory response to viral respiratory infections in children and adults. Although young children and elderly adults bear a disproportionate burden of morbidity and mortality associated with viral respiratory infections, little is known about the mechanisms placing these populations at increased risk. My lab is currently investigating the role of innate immune responses in influenza infection. Elucidation of the mechanisms underlying age-related susceptibility and resistance to disease may contribute to the broader understanding of innate immunity and its role in critical illness.

My clinical focus is the care for critically ill children in the Pediatric Intensive Care Unit (PICU). I am particularly interested in acute respiratory failure, acute respiratory distress syndrome, and mechanical ventilation.

Certifications and Licenses

Pediatric Critical Care Medicine
General Pediatrics

Training Experience

2008Internship, Northwestern University, McGaw Medical Center
2011Residency, Northwestern University, McGaw Medical Center

Education/Academic qualification

MD, University of Washington

… → 2005

Research interests

  • Critical Care
  • Immune Regulation
  • Infectious Diseases in Children
  • Inflammation
  • Lung Injury
  • Virus Diseases

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Grants

Pathophysiology of Influenza A Virus-induced Lung Injury in Juveniles

Coates, B.

National Heart, Lung, and Blood Institute

8/6/18 → 6/30/22

Project: Research project

Pathophysiology of Influenza A Virus-induced Lung Injury in Juveniles

Coates, B.

National Heart, Lung, and Blood Institute

8/6/18 → 6/30/22

Project: Research project

Immune Response to Severe Influenza Infection in Children

Coates, B.

Children's Hospital Boston

2/1/18 → 1/31/21

Project: Research project

PRone and OScillation PEdiatric Clinical Trial

Coates, B. & Marsillio, L. E.

University of Pennsylvania, National Institutes of Health

6/1/18 → 5/31/19

Project: Research project

Role of NOD- like receptor proteins in juvenile influenza A virus infection

Coates, B. & Ridge, K. M.

Respiratory Health Association of Metropolitan Chicago

7/1/16 → 6/30/17

Project: Research project

    • Research Output

    • 361 Citations
    • 8 Article
    • 2 Review article
    • 1 Comment/debate

    Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study

    Pediatric Acute Respiratory Distress syndrome Incidence and Epidemiology (PARDIE) Investigators & Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Feb 2019, In : The Lancet Respiratory Medicine. 7, 2, p. 115-128 14 p.

    Research output: Contribution to journal › Article

    • 31 Scopus citations

    Inflammatory monocytes drive influenza A virus-mediated lung injury in juvenile mice

    Coates, B. M., Staricha, K. L., Koch, C. M., Cheng, Y., Shumaker, D. K., Budinger, G. R. S., Perlman, H., Misharin, A. V. & Ridge, K. M., Apr 1 2018, In : Journal of Immunology. 200, 7, p. 2391-2404 14 p.

    Research output: Contribution to journal › Article

    • 23 Scopus citations

    Inhibition of the NOD-like receptor protein 3 inflammasome is protective in juvenile influenza a virus infection

    Coates, B. M., Staricha, K. L., Ravindran, N., Koch, C. M., Cheng, Y., Davis, J. M., Shumaker, D. K. & Ridge, K. M., Jul 10 2017, In : Frontiers in immunology. 8, JUL, 782.

    Research output: Contribution to journal › Article

    • 23 Scopus citations

    The role of nucleotide-binding oligomerization domain-like receptors in pulmonary infection

    Wiese, K. M., Coates, B. M. & Ridge, K. M., Aug 2017, In : American journal of respiratory cell and molecular biology. 57, 2, p. 151-161 11 p.

    Research output: Contribution to journal › Review article

    • 3 Scopus citations

    Influenza a virus infection, innate immunity, and childhood

    Coates, B. M., Staricha, K. L., Wiese, K. M. & Ridge, K. M., Oct 1 2015, In : JAMA Pediatrics. 169, 10, p. 956-963 8 p.

    Research output: Contribution to journal › Review article

    • 19 Scopus citations