Bria Coates

  • 166 Citations
20052020
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Personal profile

Research Interests

My clinical focus is the care for critically ill children in the Pediatric Intensive Care Unit (PICU). I am particularly interested in acute respiratory failure, acute respiratory distress syndrome, and mechanical ventilation.

My research explores differences in the inflammatory response to viral respiratory infections in children and adults. Although young children and elderly adults bear a disproportionate burden of morbidity and mortality associated with viral respiratory infections, little is known about the mechanisms placing these populations at increased risk. My lab is currently investigating the role of innate immune responses in influenza infection. Elucidation of the mechanisms underlying age-related susceptibility and resistance to disease may contribute to the broader understanding of innate immunity and its role in critical illness.

I am a physician-scientist who specializes in pediatric critical care medicine. I received my MD from the University of Washington and completed my Residency in Pediatrics and Fellowship in Critical Care Medicine at Northwestern University. I joined the faculty in the Pediatric Critical Care Division in 2011.

Certifications and Licenses

General Pediatrics
Pediatric Critical Care Medicine

Training Experience

2008Internship, Northwestern University, McGaw Medical Center
2011Residency, Northwestern University, McGaw Medical Center

Education/Academic qualification

MD, University of Washington

… → 2005

Keywords

  • Critical Care
  • Immune Regulation
  • Infectious Diseases in Children
  • Inflammation
  • Lung Injury
  • Virus Diseases

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Grants 2015 2020

Research Output 2005 2019

  • 166 Citations
  • 8 Article
  • 2 Review article
  • 1 Chapter
  • 1 Comment/debate
4 Citations (Scopus)

Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study

Pediatric Acute Respiratory Distress syndrome Incidence and Epidemiology (PARDIE) Investigators & Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Feb 1 2019, In : The Lancet Respiratory Medicine. 7, 2, p. 115-128 14 p.

Research output: Contribution to journalArticle

Adult Respiratory Distress Syndrome
Observational Studies
Epidemiology
Pediatrics
Incidence
10 Citations (Scopus)

Inflammatory monocytes drive influenza A virus-mediated lung injury in juvenile mice

Coates, B. M., Staricha, K. L., Koch, C. M., Cheng, Y., Shumaker, D. K., Budinger, G. R. S., Perlman, H., Misharin, A. V. & Ridge, K. M., Apr 1 2018, In : Journal of Immunology. 200, 7, p. 2391-2404 14 p.

Research output: Contribution to journalArticle

Influenza A virus
Lung Injury
Human Influenza
Monocytes
Inflammasomes
14 Citations (Scopus)

Inhibition of the NOD-like receptor protein 3 inflammasome is protective in juvenile influenza a virus infection

Coates, B., Staricha, K. L., Ravindran, N., Koch, C. M., Cheng, Y., Davis, J. M., Shumaker, D. K. & Ridge, K. M., Jul 10 2017, In : Frontiers in Immunology. 8, JUL, 782.

Research output: Contribution to journalArticle

Inflammasomes
Influenza A virus
Virus Diseases
Orthomyxoviridae
Proteins
1 Citation (Scopus)

The role of nucleotide-binding oligomerization domain-like receptors in pulmonary infection

Wiese, K. M., Coates, B. & Ridge, K. M., Aug 1 2017, In : American Journal of Respiratory Cell and Molecular Biology. 57, 2, p. 151-161 11 p.

Research output: Contribution to journalReview article

Pattern Recognition Receptors
Oligomerization
Pathogens
Pneumonia
Nucleotides

Wheezing in infants: Bronchiolitis.

Coates, BM., Camarda, LE. & Goodman, DM., 2016, Nelson Textbook of Pediatrics. Kliegman, RM. (ed.). Philadelphia: Elsevier

Research output: Chapter in Book/Report/Conference proceedingChapter