Grants per year
Personal profile
Research Interests
I am a physician-scientist who specializes in pediatric critical care medicine. I received my MD from the University of Washington and completed my Residency in Pediatrics and Fellowship in Critical Care Medicine at Northwestern University. I joined the faculty in the Pediatric Critical Care Division in 2011.
My research explores differences in the inflammatory response to viral respiratory infections in children and adults. Although young children and elderly adults bear a disproportionate burden of morbidity and mortality associated with viral respiratory infections, little is known about the mechanisms placing these populations at increased risk. My lab is currently investigating the role of innate immune responses in influenza infection. Elucidation of the mechanisms underlying age-related susceptibility and resistance to disease may contribute to the broader understanding of innate immunity and its role in critical illness.
My clinical focus is the care for critically ill children in the Pediatric Intensive Care Unit (PICU). I am particularly interested in acute respiratory failure, acute respiratory distress syndrome, and mechanical ventilation.
Certifications and Licenses
Pediatric Critical Care Medicine | |
General Pediatrics |
Training Experience
2008 | Internship, Northwestern University, McGaw Medical Center |
2011 | Residency, Northwestern University, McGaw Medical Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, University of Washington
… → 2005
Research interests keywords
- Critical Care
- Immune Regulation
- Infectious Diseases in Children
- Inflammation
- Lung Injury
- Virus Diseases
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Collaborations and top research areas from the last five years
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Impact of sex and NOD-like receptor activation in prepubertal influenza A virus infection
2/1/19 → 2/28/20
Project: Research project
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Pathophysiology of Influenza A Virus-induced Lung Injury in Juveniles
National Heart, Lung, and Blood Institute
8/6/18 → 6/30/22
Project: Research project
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Pathophysiology of Influenza A Virus-induced Lung Injury in Juveniles
National Heart, Lung, and Blood Institute
8/6/18 → 6/30/22
Project: Research project
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Association of Asthma With Treatments and Outcomes in Children With Critical Influenza
PALISI Pediatric Intensive Care Influenza Network Investigators, Mar 2023, In: Journal of Allergy and Clinical Immunology: In Practice. 11, 3, p. 836-843.e3Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
BNT162b2 mRNA Vaccination Against Coronavirus Disease 2019 is Associated With a Decreased Likelihood of Multisystem Inflammatory Syndrome in Children Aged 5-18 Years - United States, July 2021 - April 2022
Zambrano, L. D., Newhams, M. M., Olson, S. M., Halasa, N. B., Price, A. M., Orzel, A. O., Young, C. C., Boom, J. A., Sahni, L. C., Maddux, A. B., Bline, K. E., Kamidani, S., Tarquinio, K. M., Chiotos, K., Schuster, J. E., Cullimore, M. L., Heidemann, S. M., Hobbs, C. V., Nofziger, R. A., Pannaraj, P. S., & 22 others , Feb 1 2023, In: Clinical Infectious Diseases. 76, 3, p. E90-E100Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Children and Adolescents With COVID-19 or Multisystem Inflammatory Syndrome Admitted to U.S. ICUs
Overcoming COVID-19 Investigators, May 1 2023, In: Pediatric Critical Care Medicine. 24, 5, p. 356-371 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Factors Associated With COVID-19 Non-vaccination in Adolescents Hospitalized Without COVID-19
Sahni, L. C., Price, A. M., Olson, S. M., Newhams, M. M., Pannaraj, P. S., Maddux, A. B., Halasa, N. B., Bline, K. E., Cameron, M. A., Schwartz, S. P., Walker, T. C., Irby, K., Chiotos, K., Nofziger, R. A., Mack, E. H., Smallcomb, L., Bradford, T. T., Kamidani, S., Tarquinio, K. M., Cvijanovich, N. Z., & 19 others , Feb 9 2023, In: Journal of the Pediatric Infectious Diseases Society. 12, 1, p. 29-35 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children
Halasa, N. B., Spieker, A. J., Young, C. C., Olson, S. M., Newhams, M. M., Amarin, J. Z., Moffitt, K. L., Nakamura, M. M., Levy, E. R., Soma, V. L., Talj, R., Weiss, S. L., Fitzgerald, J. C., Mack, E. H., Maddux, A. B., Schuster, J. E., Coates, B. M., Hall, M. W., Schwartz, S. P., Schwarz, A. J., & 22 others , Feb 1 2023, In: Clinical Infectious Diseases. 76, 3, p. E280-E290Research output: Contribution to journal › Article › peer-review
3 Scopus citations