Personal profile

Research Interests

Our research involves electron-nuclear double resonance study of metallo-enzymes, long-range electron transfer between proteins, and new macro-cycles for solid-state and biomedical applications.

Education / Academic qualification

PhD, California Institute of Technology

BS, University of Chicago

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Electron Spin Resonance Spectroscopy Medicine & Life Sciences
Paramagnetic resonance Chemical Compounds
Electrons Chemical Compounds
Nitrogenase Chemical Compounds
Molybdoferredoxin Medicine & Life Sciences
Heme Medicine & Life Sciences
Spectrum Analysis Medicine & Life Sciences
Ligands Chemical Compounds

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Research Output 1967 2018

A structurally-characterized peroxomanganese(IV) porphyrin from reversible O2 binding within a metal-organic framework

Gallagher, A. T., Lee, J. Y., Kathiresan, V., Anderson, J. S., Hoffman, B. M. & Harris, T. D. Jan 1 2018 In : Chemical Science. 9, 6, p. 1596-1603 8 p.

Research output: Contribution to journalArticle

Porphyrins
Metals
Paramagnetic resonance
Enthalpy
Metalloporphyrins

Cu+-specific CopB transporter: Revising p1B-type ATPase classification

Purohit, R., Ross, M. O., Batelu, S., Kusowski, A., Stemmler, T. L., Hoffman, B. M. & Rosenzweig, A. C. Feb 27 2018 In : Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. 2108-2113 6 p.

Research output: Contribution to journalArticle

sulfur
copper
bioinformatics
metal
homeostasis
1 Citations

Mechanism of N2 Reduction Catalyzed by Fe-Nitrogenase Involves Reductive Elimination of H2

Harris, D. F., Lukoyanov, D. A., Shaw, S., Compton, P., Tokmina-Lukaszewska, M., Bothner, B., Kelleher, N., Dean, D. R., Hoffman, B. M. & Seefeldt, L. C. Feb 6 2018 In : Biochemistry. 57, 5, p. 701-710 10 p.

Research output: Contribution to journalArticle

Nitrogenase
Proteins
Protons
Catalytic Domain
Molybdoferredoxin

Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis

Dong, M., Kathiresan, V., Fenwick, M. K., Torelli, A. T., Zhang, Y., Caranto, J. D., Dzikovski, B., Sharma, A., Lancaster, K. M., Freed, J. H., Ealick, S. E., Hoffman, B. M. & Lin, H. Mar 16 2018 In : Science. 359, 6381, p. 1247-1250 4 p.

Research output: Contribution to journalArticle

Biosynthesis
Organometallics
S-Adenosylmethionine
Carbon
Sulfur
8 Citations

13C ENDOR spectroscopy of lipoxygenase-substrate complexes reveals the structural basis for C-H activation by tunneling

Horitani, M., Offenbacher, A. R., Marcus Carr, C. A., Yu, T., Hoeke, V., Cutsail, G. E., Hammes-Schiffer, S., Klinman, J. P. & Hoffman, B. M. Feb 8 2017 In : Journal of the American Chemical Society. 139, 5, p. 1984-1997 14 p.

Research output: Contribution to journalArticle

Lipoxygenase
Electron Spin Resonance Spectroscopy
Soybeans
Spectrum Analysis
Chemical activation