Bruce Kuang-Huay Tan

Personal profile

Research Interests

Sinusitis, chronic sinusitis, nasal polyps, nasal tumors, smell and taste disturbances, minimally invasive approaches to the skull base, inflammation, mechanisms of smell loss from inflammation, therapeutics and diagnostic approaches for sinus disease

Certifications and Licenses

Otolaryngology

Training Experience

2005	Internship, Johns Hopkins Hospital
2009	Residency, Johns Hopkins Hospital
2010	Fellowship, Northwestern University, McGaw Medical Center

Education/Academic qualification

MD, University of Chicago

… → 2004

Research interests

Allergies
Clinical Research
Minimally Invasive Surgery
Otolaryngology
Skull Base Surgery

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11 Similar Profiles

Nasal Polyps Medicine & Life Sciences

Nose Medicine & Life Sciences

Sinusitis Medicine & Life Sciences

Rhinitis Medicine & Life Sciences

Chronic Disease Medicine & Life Sciences

Inflammation Medicine & Life Sciences

Paranasal Sinuses Medicine & Life Sciences

Asthma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2011 2024

5 Active
9 Finished

Core B: Clinical, Laboratory and Data Management Core

Kato, A., Kern, R. C., Smith, S. S. & Tan, B. K.

National Institute of Allergy and Infectious Diseases

8/15/19 → 7/31/24

Project: Research project

Natural History

Phenotype

Comorbidity

Longitudinal Studies

Bronchiectasis

Project 1: Mechanisms of barrier dysfunction and tissue hyperplasia in CRS

Berdnikovs, S., Hulse, K. E., Kern, R. C., Peters, A. T., Schleimer, R. P. & Tan, B. K.

National Institute of Allergy and Infectious Diseases

8/15/19 → 7/31/24

Project: Research project

Hyperplasia

Natural History

Phenotype

Comorbidity

Longitudinal Studies

Type-2 inflammation mediates olfactory loss in Chronic Rhinosinusitis: mechanisms and therapeutic opportunities

Avram, M. J., Chmiel, J. S., Schleimer, R. P. & Tan, B. K.

National Institute on Deafness and Other Communication Disorders

7/23/18 → 6/30/23

Project: Research project

Smell

Inflammation

Proton-Translocating ATPases

Therapeutics

Ion Pumps

Autoantibody mediated pathogenesis in chronic rhinosinusitis with nasal polyps: mechanisms and consequences

Hulse, K. E., Schleimer, R. P. & Tan, B. K.

National Institute of Allergy and Infectious Diseases

5/25/18 → 4/30/23

Project: Research project

Nasal Polyps

Autoantibodies

B-Lymphocytes

Antibodies

Antigens

Initiators, biomarkers and mechanisms of epithelial dysfunction and immune pathogenesis in chronic rhinosinusitis and aspirin exacerbated respiratory disease (AERD)

Berdnikovs, S., Hulse, K. E., Kato, A., Kern, R. C., Peters, A. T., Rademaker, A. W., Schleimer, R. P. & Tan, B. K.

National Institute of Allergy and Infectious Diseases

2/15/18 → 2/14/23

Project: Research project

Aspirin

Nasal Polyps

Biomarkers

Epithelial-Mesenchymal Transition

Mast Cells

Research Output 2009 2020

2704 Citations
96 Article
10 Review article
5 Letter
2 Editorial

Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps

Ogasawara, N., Poposki, J. A., Klingler, A. I., Tan, B. K., Hulse, K. E., Stevens, W. W., Peters, A. T., Grammer, L. C., Welch, K. C., Smith, S. S., Conley, D. B., Raviv, J. R., Soroosh, P., Takano, K. I., Himi, T., Kern, R. C., Schleimer, R. P. & Kato, A., Jan 1 2020, In : Mucosal Immunology. 13, 1, p. 86-95 10 p.

Research output: Contribution to journal › Article

Nasal Polyps

Inflammation

Cytokines

RANK Ligand

Coculture Techniques

1 Citation (Scopus)

TNF induces production of type 2 cytokines in human group 2 innate lymphoid cells

Ogasawara, N., Poposki, J. A., Klingler, A. I., Tan, B. K., Hulse, K. E., Stevens, W. W., Peters, A. T., Grammer, L. C., Welch, K. C., Smith, S. S., Conley, D. B., Takano, K. I., Himi, T., Kern, R. C., Schleimer, R. P. & Kato, A., Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 437-440.e8

Research output: Contribution to journal › Article

Lymphocytes

Cytokines

1 Citation (Scopus)

Are chronic cough and laryngopharyngeal reflux more common in obstructive sleep apnea patients?

Gouveia, C. J., Yalamanchili, A., Ghadersohi, S., Price, C. P. E., Bove, M., Attarian, H. P. & Tan, B. K., May 2019, In : Laryngoscope. 129, 5, p. 1244-1249 6 p.

Research output: Contribution to journal › Article

Laryngopharyngeal Reflux

Obstructive Sleep Apnea

Cough

Apnea

Sleep Apnea Syndromes

5 Citations (Scopus)