Bruce Scott Bochner

  • Source: Scopus
1978 …2021

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Personal profile

Research Interests

My lab's primary research interest is on Siglec-8, a receptor expressed on human eosinophils and mast cells, how it signals and functions, what are its natural sialoside ligands, and whether it can be leveraged as a therapeutic target. Regarding the latter, we have generated Siglec-8 knock-in mice for preclinical studies of Siglec-8 biology and targeting in mouse models. We have also initiated studies on Siglec-6 function in human mast cells, and how pharmacologic inhibition of Bruton's tyrosine kinase (BTK) in mast cells and basophils protects from anaphylaxis in vitro and in vivo.

My primary clinical interests are in eosinophil- and mast-cell associated diseases, including hypereosinophilic syndromes and systemic mastocytosis. I am also interested in anaphylaxis and other allergic diseases.

My primary clinical interests are in eosinophil- and mast-cell associated diseases.

Certifications and Licenses

Internal Medicine
Allergy & Immunology

Training Experience

1985Residency, University of Illinois Medical Center
1988Fellowship, Johns Hopkins University School of Medicine

Expertise related to UN Sustainable Devlopment Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Medicine, MD, University of Illinois at Chicago

… → 1982

Research interests

  • Allergies
  • Asthma
  • Eosinophilic Esophagitis
  • Eosinophilic Gastrointestinal Disease
  • Food Allergy
  • Inflammation

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