Bruce Scott Bochner

  • 13642 Citations
1978 …2023
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Research Output 1978 2019

2007
225 Citations (Scopus)

Risk assessment in anaphylaxis: Current and future approaches

Simons, F. E. R., Frew, A. J., Ansotegui, I. J., Bochner, B. S., Golden, D. B. K., Finkelman, F. D., Leung, D. Y. M., Lotvall, J., Marone, G., Metcalfe, D. D., Müller, U., Rosenwasser, L. J., Sampson, H. A., Schwartz, L. B., van Hage, M. & Walls, A. F., Jul 1 2007, In : Journal of Allergy and Clinical Immunology. 120, 1 SUPPL.

Research output: Contribution to journalArticle

Anaphylaxis
Allergens
Tryptases
Mast Cells
Basophils
9 Citations (Scopus)

Siglec-8 and siglec-F: Inhibitory receptors on eosinophils, basophils, and mast cells

Guo, J. P., Nutku, E., Yokoi, H., Schnaar, R. L., Zimmermann, N. & Bochner, B. S., Mar 1 2007, In : Allergy and Clinical Immunology International. 19, 2, p. 54-59 6 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Basophils
Eosinophils
Mast Cells
Polysaccharides
2006
47 Citations (Scopus)

Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells

Yokoi, H., Myers, A., Matsumoto, K., Crocker, P. R., Saito, H. & Bochner, B. S., Jun 1 2006, In : Allergy: European Journal of Allergy and Clinical Immunology. 61, 6, p. 769-776 8 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Mast Cells
In Vitro Techniques
Sialic Acid Binding Ig-like Lectin 2
Flow Cytometry
261 Citations (Scopus)

Approaches to the treatment of hypereosinophilic syndromes: A workshop summary report

Klion, A. D., Bochner, B. S., Gleich, G. J., Nutman, T. B., Rothenberg, M. E., Simon, H. U., Wechsler, M. E., Weller, P. F. & the Hypereosinophilic Syndromes Working Group, H. S. W. G., Jun 1 2006, In : Journal of Allergy and Clinical Immunology. 117, 6, p. 1292-1302 11 p.

Research output: Contribution to journalArticle

Hypereosinophilic Syndrome
Education
Eosinophilia
Therapeutics
Eosinophils
27 Citations (Scopus)

Stimulation of human endothelium with IL-3 induces selective basophil accumulation in vitro

Lim, L. H. K., Burdick, M. M., Hudson, S. A., Mustafa, F. B., Konstantopoulos, K. & Bochner, B. S., May 1 2006, In : Journal of Immunology. 176, 9, p. 5346-5353 8 p.

Research output: Contribution to journalArticle

Basophils
Interleukin-3
Endothelium
In Vitro Techniques
Endothelial Cells
1 Citation (Scopus)

Understanding the ingenuity of chemokines and their receptors

Bochner, B. S., Aug 1 2006, In : Journal of Allergy and Clinical Immunology. 118, 2, p. 321-323 3 p.

Research output: Contribution to journalEditorial

Chemokine Receptors
Chemokines
Eosinophils
HIV
Viruses
2005
126 Citations (Scopus)

Allergy and asthma

Bochner, B. S. & Busse, W. W., Jan 1 2005, In : Journal of Allergy and Clinical Immunology. 115, 5, p. 953-959 7 p.

Research output: Contribution to journalReview article

Genetic Polymorphisms
Allergy and Immunology
Smooth Muscle
Hypersensitivity
Asthma
191 Citations (Scopus)

Glycan array screening reveals a candidate ligand for Siglec-8

Bochner, B. S., Alvarez, R. A., Mehta, P., Bovin, N. V., Blixt, O., White, J. R. & Schnaar, R. L., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 4307-4312 6 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Polysaccharides
Screening
Ligands
Glycosides
3 Citations (Scopus)

Introduction: Anti-IgE

Bochner, B. & Saini, S., Aug 1 2005, In : Clinical Reviews in Allergy and Immunology. 29, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

IgE Receptors
Seasonal Allergic Rhinitis
Food Hypersensitivity
Immunoglobulin E
Hypersensitivity
68 Citations (Scopus)

Mechanism of Siglec-8-induced human eosinophil apoptosis: Role of caspases and mitochondrial injury

Nutku, E., Hudson, S. A. & Bochner, B. S., Oct 28 2005, In : Biochemical and Biophysical Research Communications. 336, 3, p. 918-924 7 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Caspases
Eosinophils
Apoptosis
Wounds and Injuries
2004
20 Citations (Scopus)

Adhesion molecules as therapeutic targets

Bochner, B. S., Jan 1 2004, In : Immunology and Allergy Clinics of North America. 24, 4 SPEC. ISS., p. 615-630 16 p.

Research output: Contribution to journalReview article

Inflammation
Cell Adhesion Molecules
Leukocytes
Animal Models
Therapeutics
35 Citations (Scopus)

Advances in mechanisms of allergy

Bochner, B. S. & Busse, W. W., Jan 1 2004, In : Journal of Allergy and Clinical Immunology. 113, 5, p. 868-875 8 p.

Research output: Contribution to journalReview article

Hypersensitivity
Allergy and Immunology
Allergens
Cell Biology
Pharmacology
3 Citations (Scopus)

Chapter 6. Function of Siglec-8 on human eosinophils

Nutku, E., Aizawa, H., Hudson, S. & Bochner, B. S., Dec 1 2004, In : Clinical and Experimental Allergy Reviews. 4, SUPPL. 2, p. 76-81 6 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Eosinophils
Tyrosine
Interleukin-5
Sialic Acid Binding Ig-like Lectin 1
85 Citations (Scopus)

Gene expression profiles in human nasal polyp tissues studied by means of DNA microarray

Liu, Z., Kim, J., Sypek, J. P., Wang, I. M., Horton, H., Oppenheim, F. G. & Bochner, B. S., Oct 1 2004, In : Journal of Allergy and Clinical Immunology. 114, 4, p. 783-790 8 p.

Research output: Contribution to journalArticle

Nasal Polyps
Oligonucleotide Array Sequence Analysis
Transcriptome
Nose
Genes

Session 3. Immune cells in allergic disorders

Marone, G., Lichtenstein, L. M., Mantovani, A., Bonini, S., Rossi, G., Walls, A., Wang, J. M., Schleimer, R. P., Wardlaw, A., Platts-Mills, T. A., Galli, S., Bochner, B. S., Triggiani, M., Wardlaw, A. J., Holgate, S. T., Katz, H. R., Ring, J. & Lambrecht, B., Dec 1 2004, In : Clinical and Experimental Allergy Reviews. 4, SUPPL. 2, p. 85-88 4 p.

Research output: Contribution to journalArticle

Session 4. 'Evergreen' mediators in asthma

Austen, K. F., Dahlén, S. E., Holgate, S. T., Wang, J. M., Galli, S. J., Poto, S., Caughey, G. H., Marone, G., Stevens, R. L., Platts-Mills, T., Schleimer, R. P., Wardlaw, A. J., Kay, A. B., Bonini, S., Sinigaglia, F., Bochner, B., Lucivero, G. & Walls, A., Dec 1 2004, In : Clinical and Experimental Allergy Reviews. 4, SUPPL. 2, p. 118-122 5 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Verdict in the case of therapies versus eosinophils: The jury is still out

Bochner, B. S., Jan 1 2004, In : Journal of Allergy and Clinical Immunology. 113, 1, p. 3-9 7 p.

Research output: Contribution to journalReview article

Eosinophils
Asthma
Therapeutics
Eosinophilia
Inflammation
2003
14 Citations (Scopus)

Advances in mechanisms of allergy

Bochner, B. S. & Hamid, Q., Mar 1 2003, In : Journal of Allergy and Clinical Immunology. 111, SUPPL. 3

Research output: Contribution to journalReview article

Animal Disease Models
Basophils
Ovalbumin
Allergy and Immunology
Eosinophils
36 Citations (Scopus)

CD8+ T lymphocytes in viral hyperreactivity and M2 muscarinic receptor dysfunction.

Adamko, D. J., Fryer, A. D., Bochner, B. S. & Jacoby, D. B., Jan 1 2003, In : American Journal of Respiratory and Critical Care Medicine. 167, 4, p. 550-556 7 p.

Research output: Contribution to journalArticle

Muscarinic M2 Receptors
Eosinophils
T-Lymphocytes
Viruses
Guinea Pigs

Cellular adhesion in inflammation

Bochner, BS., 2003, Middleton’s Allergy Principles and Practice. 6th Edition. Adkinson, NF., Yunginger, JW., Busse, WW., Bochner, BS., Holgate, ST. & Simons, FER. (eds.). St. Louis: Mosby, p. 117-134

Research output: Chapter in Book/Report/Conference proceedingChapter

94 Citations (Scopus)

Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow

Burdick, M. M., Michael McCaffery, J., Kim, Y. S., Bochner, B. S. & Konstantopoulos, K., Apr 1 2003, In : American Journal of Physiology - Cell Physiology. 284, 4 53-4

Research output: Contribution to journalArticle

Glycolipids
Human Umbilical Vein Endothelial Cells
Integrins
E-Selectin
Glycoproteins
26 Citations (Scopus)

Exogenous eosinophil activation converts PSGL-1-dependent binding to CD18-dependent stable adhesion to platelets in shear flow

McCarty, O. J. T., Tien, N., Bochner, B. S. & Konstantopoulos, K., May 1 2003, In : American Journal of Physiology - Cell Physiology. 284, 5 53-5

Research output: Contribution to journalArticle

Eosinophils
Blood Platelets
P-Selectin
L-Selectin
Chemokine CCL24
36 Citations (Scopus)

Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells

Kurosawa, S., Myers, A. C., Chen, L., Wang, S., Ni, J., Plitt, J. R., Heller, N. M., Bochner, B. S. & Schleimer, R. P., May 1 2003, In : American Journal of Respiratory Cell and Molecular Biology. 28, 5, p. 563-573 11 p.

Research output: Contribution to journalArticle

Inducible T-Cell Co-Stimulator Protein
B7 Antigens
Epithelial Cells
Ligands
Antigen Presentation
5 Citations (Scopus)

Leukocyte recruitment in allergic pulmonary inflammation

Bochner, B. S., Jan 1 2003, Therapeutic Targets in Airway Inflammation. CRC Press, p. 223-248 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pneumonia
Leukocytes
Basophils
Eosinophils
Allergens
211 Citations (Scopus)

Ligation of Siglec-8: A selective mechanism for induction of human eosinophil apoptosis

Nutku, E., Aizawa, H., Hudson, S. A. & Bochner, B. S., Jun 15 2003, In : Blood. 101, 12, p. 5014-5020 7 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Eosinophils
Ligation
Apoptosis
Basophils
38 Citations (Scopus)

Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: Identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G)

Aizawa, H., Zimmermann, N., Carrigan, P. E., Lee, J. J., Rothenberg, M. E. & Bochner, B. S., Nov 1 2003, In : Genomics. 82, 5, p. 521-530 10 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Eosinophils
Northern Blotting
Messenger RNA
Interleukin-5
9 Citations (Scopus)

Phorbol esters alter α4 and αd integrin usage during eosinophil adhesion to VCAM-1

Kikuchi, M., Tachimoto, H., Nutku, E., Hudson, S. A. & Bochner, B. S., May 1 2003, In : Cell Communication and Adhesion. 10, 3, p. 119-128 10 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Phorbol Esters
Eosinophils
Integrins
Adhesion
123 Citations (Scopus)

Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions

Bochner, B. S., Hudson, S. A., Xiao, H. Q. & Liu, M. C., Jan 1 2003, In : Journal of Allergy and Clinical Immunology. 112, 5, p. 930-934 5 p.

Research output: Contribution to journalArticle

Chemokines
Chemokine CCL22
Chemokine CCL17
Lung
Allergens
2002
2 Citations (Scopus)

Cell surface expression of a specific antigenic site on the catalytic subunit of (Na+ + K+)-ATPase

Myers, A. C., Bochner, B. S., Tomaselli, G. F., Fedarko, N., Hudson, S. A., Rohde, H., Huang, S. K. & Xu, K. Y., Jan 1 2002, In : Biochemical and Biophysical Research Communications. 291, 1, p. 111-115 5 p.

Research output: Contribution to journalArticle

Adenosine Triphosphatases
Catalytic Domain
Peptides
Cell membranes
Cercopithecus aethiops
21 Citations (Scopus)

Cross-talk between integrins and chemokines that influences eosinophil adhesion and migration

Tachimoto, H., Ebisawa, M. & Bochner, B. S., Jun 26 2002, In : International Archives of Allergy and Immunology. 128, SUPPL. 1, p. 18-20 3 p.

Research output: Contribution to journalArticle

Chemokine Receptors
Chemokines
Eosinophils
Cell Adhesion
Integrins
19 Citations (Scopus)

Eotaxin-2 alters eosinophil integrin function via mitogen-activated protein kinases

Tachimoto, H., Kikuchi, M., Hudson, S. A., Bickel, C. A., Hamilton, R. G. & Bochner, B. S., Jan 1 2002, In : American Journal of Respiratory Cell and Molecular Biology. 26, 6, p. 645-649 5 p.

Research output: Contribution to journalArticle

Chemokine CCL24
Intercellular Adhesion Molecule-1
Vascular Cell Adhesion Molecule-1
Mitogen-Activated Protein Kinases
Eosinophils
39 Citations (Scopus)

Expression of activation markers on alveolar macrophages in allergic asthmatics after endobronchial or whole-lung allergen challenge

Viksman, M. Y., Bochner, B. S., Peebles, R. S., Schleimer, R. P. & Liu, M. C., Jan 1 2002, In : Clinical Immunology. 104, 1, p. 77-85 9 p.

Research output: Contribution to journalArticle

Alveolar Macrophages
Allergens
HLA-DQ Antigens
Lung
Phleum
23 Citations (Scopus)

Human eosinophils express two Siglec-8 splice variants [1]

Aizawa, H., Plitt, J. & Bochner, B. S., Jan 1 2002, In : Journal of Allergy and Clinical Immunology. 109, 1, 1 p.

Research output: Contribution to journalLetter

Sialic Acid Binding Immunoglobulin-like Lectins
Eosinophils
5 Citations (Scopus)

Leukocyte-blood vessel interactions.

Davenpeck, K. L. & Bochner, B. S., Jan 1 2002, In : Clinical allergy and immunology. 16, p. 125-141 17 p.

Research output: Contribution to journalReview article

Vascular Endothelium
Cell Adhesion Molecules
Cell Adhesion
Blood Vessels
Hypersensitivity
28 Citations (Scopus)
Microcirculation
Leukocytes
Leukocyte Rolling
Venules
Lipopolysaccharides
7 Citations (Scopus)

Methods to track leukocyte and erythrocyte transit through the bronchial vasculature in sheep

Gallagher, S. J., Shank, J. A., Bochner, B. S. & Wagner, E. M., Dec 20 2002, In : Journal of Immunological Methods. 271, 1-2, p. 89-97 9 p.

Research output: Contribution to journalArticle

Sheep
Leukocytes
Erythrocytes
L-Selectin
Bronchial Arteries
2001
24 Citations (Scopus)

Acquisition and alteration of adhesion molecules during cultured human mast cell differentiation

Tachimoto, H., Hudson, S. A. & Bochner, B. S., Jan 1 2001, In : Journal of Allergy and Clinical Immunology. 107, 2, p. 302-309 8 p.

Research output: Contribution to journalArticle

Mast Cells
Cell Differentiation
Integrins
Extracellular Matrix Proteins
Aspartic Acid
62 Citations (Scopus)

Effects of prednisone on the cellular responses and release of cytokines and mediators after segmental allergen challenge of asthmatic subjects

Liu, M. C., Proud, D., Lichtenstein, L. M., Hubbard, W. C., Bochner, B. S., Stealey, B. A., Breslin, L., Xiao, H. Q., Freidhoff, L. R., Schroeder, J. T. & Schleimer, R. P., Jan 1 2001, In : Journal of Allergy and Clinical Immunology. 108, 1, p. 29-38 10 p.

Research output: Contribution to journalArticle

Prednisone
Allergens
Cytokines
Bronchoalveolar Lavage Fluid
Glucocorticoids
54 Citations (Scopus)

Expression and rodulation of FcεRIα and FcεRIβ in human blood basophils

Saini, S. S., Richardson, J. J., Wofsy, C., Lavens-Phillips, S., Bochner, B. S. & MacGlashan, D. W., Jan 1 2001, In : Journal of Allergy and Clinical Immunology. 107, 5 SUPPL., p. 832-841 10 p.

Research output: Contribution to journalArticle

Basophils
Interleukin-3
Proteins
Flow Cytometry
Eosinophils
35 Citations (Scopus)

Glycolipids support E-selectin-specific strong cell tethering under flow

Burdick, M. M., Bochner, B. S., Collins, B. E., Schnaar, R. L. & Konstantopoulos, K., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 284, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

Glycosphingolipids
E-Selectin
Glycolipids
Cricetulus
Ovary
15 Citations (Scopus)

Human eosinophils constitutively express nuclear factor of activated T cells p and c

Seminario, M. C., Guo, J., Bochner, B. S., Beck, L. A. & Georas, S. N., Jan 1 2001, In : Journal of Allergy and Clinical Immunology. 107, 1, p. 143-152 10 p.

Research output: Contribution to journalArticle

NFATC Transcription Factors
Eosinophils
Cytokines
Interleukin-4
Bronchoalveolar Lavage Fluid
11 Citations (Scopus)
Vitronectin
Mast Cells
Integrins
Skin
67 Citations (Scopus)

Hydrodynamic shear regulates the kinetics and receptor specificity of polymorphonuclear leukocyte-colon carcinoma cell adhesive interactions

Jadhav, S., Bochner, B. S. & Konstantopoulos, K., Nov 15 2001, In : Journal of Immunology. 167, 10, p. 5986-5993 8 p.

Research output: Contribution to journalArticle

Hydrodynamics
Cell Communication
Adhesives
Colon
Neutrophils
139 Citations (Scopus)

Mast cells, basophils, and eosinophils: Distinct but overlapping pathways for recruitment

Bochner, B. S. & Schleimer, R. P., Mar 6 2001, In : Immunological Reviews. 179, p. 5-15 11 p.

Research output: Contribution to journalReview article

Basophils
Eosinophils
Mast Cells
Bone Marrow Cells
Inflammation
2000
96 Citations (Scopus)

Activation of human leukocytes reduces surface P-selectin glycoprotein ligand-1 (PSGL-1, CD162) and adhesion to P-selectin in vitro

Davenpeck, K. L., Brummet, M. E., Hudson, S. A., Mayer, R. J. & Bochner, B. S., Sep 1 2000, In : Journal of Immunology. 165, 5, p. 2764-2772 9 p.

Research output: Contribution to journalArticle

P-Selectin
Leukocytes
Neutrophils
P-selectin ligand protein
In Vitro Techniques
49 Citations (Scopus)

CCR3-active chemokines promote rapid detachment of eosinophils from VCAM-1 in vitro

Tachimoto, H., Burdick, M. M., Hudson, S. A., Kikuchi, M., Konstantopoulos, K. & Bochner, B. S., Sep 1 2000, In : Journal of Immunology. 165, 5, p. 2748-2754 7 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Chemokines
Eosinophils
Chemokine CCL24
Integrins
8 Citations (Scopus)

Expression and function of P-selectin glycoprotein ligand 1 (CD162) on human basophils

Taylor, M. L., Brummet, M. E., Hudson, S. A., Miura, K. & Bochner, B. S., Jan 1 2000, In : Journal of Allergy and Clinical Immunology. 106, 5, p. 918-924 7 p.

Research output: Contribution to journalArticle

Basophils
P-Selectin
Eosinophils
Neutrophils
Histamine Release
39 Citations (Scopus)

Extensive surface phenotyping of alveolar macrophages in interstitial lung disease

Taylor, M. L., Noble, P. W., White, B., Wise, R., Liu, M. C. & Bochner, B. S., Jan 1 2000, In : Clinical Immunology. 94, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Interstitial Lung Diseases
Alveolar Macrophages
Macrophages
Asthma
Idiopathic Pulmonary Fibrosis
106 Citations (Scopus)

Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils

Kikly, K. K., Bochner, B. S., Freeman, S. D., Tan, K. B., Gallagher, K. T., D'Alessio, K. J., Holmes, S. D., Abrahamson, J. A., Erickson-Miller, C. L., Murdock, P. R., Tachimoto, H., Schleimer, R. P. & White, J. R., Jan 1 2000, In : Journal of Allergy and Clinical Immunology. 105, 6 II, p. 1093-1100 8 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Basophils
Eosinophils
Mast Cells
Sialic Acid Binding Ig-like Lectin 1
63 Citations (Scopus)

Inhibition of adhesion of human neutrophils and eosinophils to P- selectin by the sialyl Lewis(x) antagonist TBC1269: Preferential activity against neutrophil adhesion in vitro

Davenpeck, K. L., Berens, K. L., Dixon, R. A. F., Dupre, B. & Bochner, B. S., Jan 1 2000, In : Journal of Allergy and Clinical Immunology. 105, 4, p. 769-775 7 p.

Research output: Contribution to journalArticle

P-Selectin
Eosinophils
Neutrophils
Selectins
Carbohydrates