Bruce Scott Bochner

  • 13642 Citations
1978 …2023
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Research Output 1978 2019

2000
36 Citations (Scopus)

Reciprocal regulation of cultured human mast cell cytokine production by IL-4 and IFN-γ

Tachimoto, H., Ebisawa, M., Hasegawa, T., Kashiwabara, T., Ra, C., Bochner, B. S., Miura, K. & Saito, H., Jan 1 2000, In : Journal of Allergy and Clinical Immunology. 106, 1 I, p. 141-149 9 p.

Research output: Contribution to journalArticle

Mast Cells
Interleukin-4
Cytokines
Macrophage Inflammatory Proteins
Granulocyte-Macrophage Colony-Stimulating Factor
44 Citations (Scopus)

Road signs guiding leukocytes along the inflammation superhighway

Bochner, B. S., Jan 1 2000, In : Journal of Allergy and Clinical Immunology. 106, 5, p. 817-828 12 p.

Research output: Contribution to journalArticle

Leukocytes
Inflammation
Chemokines
Eosinophils
B-Lymphocytes
97 Citations (Scopus)
Basophils
Eosinophils
Eosinophil Cationic Protein
Leukotriene C4
Interleukin-13
101 Citations (Scopus)

The relationship between serum IgE and surface levels of FcεR on human leukocytes in various diseases: Correlation of expression with FcεRI on basophils but not on monocytes or eosinophils

Saini, S. S., Klion, A. D., Holland, S. M., Hamilton, R. G., Bochner, B. S. & MacGlashan, D. W., Jan 1 2000, In : Journal of Allergy and Clinical Immunology. 106, 3, p. 514-520 7 p.

Research output: Contribution to journalArticle

Basophils
Eosinophils
Immunoglobulin E
Monocytes
Leukocytes
51 Citations (Scopus)

The surface phenotype of human eosinophils

Tachimoto, H. & Bochner, B. S., Mar 16 2000, In : Chemical Immunology. 76, p. 45-62 18 p.

Research output: Contribution to journalReview article

IgG Receptors
Cytokine Receptors
Chemokine Receptors
Cell Adhesion Molecules
Eosinophils
1999
186 Citations (Scopus)

Down-regulation of human basophil IgE and FCεRIα surface densities and mediator release by anti-IgE-infusions is reversible in vitro and in vivo

Saini, S. S., Macglashan, D. W., Sterbinsky, S. A., Togias, A., Adelman, D. C., Lichtenstein, L. M. & Bochner, B. S., May 1 1999, In : Journal of Immunology. 162, 9, p. 5624-5630 7 p.

Research output: Contribution to journalArticle

Basophils
Immunoglobulin E
Down-Regulation
Histamine Release
In Vitro Techniques
12 Citations (Scopus)

Functional expression of transmembrane 4 superfamily molecules on human eosinophils

Matsumoto, K., Bochner, B. S., Wakiguchi, H. & Kurashige, T., Oct 8 1999, In : International archives of allergy and immunology. 120, SUPPL. 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

Eosinophils
Flow Cytometry
Indirect Fluorescent Antibody Technique
Integrins
Signal Transduction
83 Citations (Scopus)

Immunolocalization of CD34 in nasal polyposis: Effect of topical corticosteroids

Kim, Y. K., Uno, M., Hamilos, D. L., Beck, L., Bochner, B., Schleimer, R. & Denburg, J. A., Jan 1 1999, In : American Journal of Respiratory Cell and Molecular Biology. 20, 3, p. 388-397 10 p.

Research output: Contribution to journalArticle

Nasal Polyps
Nose
Endothelial cells
Adrenal Cortex Hormones
Steroids
76 Citations (Scopus)

Inhibition of VCAM-1 expression in human bronchial epithelial cells by glucocorticoids

Atsuta, J., Plitt, J., Bochner, B. S. & Schleimer, R. P., Jan 1 1999, In : American journal of respiratory cell and molecular biology. 20, 4, p. 643-650 8 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Glucocorticoids
Epithelial Cells
Intercellular Adhesion Molecule-1
Tumor Necrosis Factor-alpha
65 Citations (Scopus)

Intracellular expression and release of FcεRIα by human eosinophils

Seminario, M. C., Saini, S. S., MacGlashan, D. W. & Bochner, B. S., Jun 1 1999, In : Journal of Immunology. 162, 11, p. 6893-6900 8 p.

Research output: Contribution to journalArticle

Eosinophils
Immunoglobulin E
Immunoprecipitation
Western Blotting
Biotinylation
59 Citations (Scopus)

Macrophage-derived chemokine induces human eosinophil chemotaxis in a CC chemokine receptor 3- and CC chemokine receptor 4-independent manner

Bochner, B. S., Bickel, C. A., Taylor, M. L., MacGlashan D.W., J., Gray, P. W., Raport, C. J. & Godiska, R., Dec 1 1999, In : Journal of Allergy and Clinical Immunology. 103, 3 II, p. 527-532 6 p.

Research output: Contribution to journalArticle

CCR4 Receptors
CCR3 Receptors
Chemokine CCL22
Chemotaxis
Eosinophils
75 Citations (Scopus)

The leukocyte integrin α(D)β2 binds VCAM-1: Evidence for a binding interface between I domain and VCAM-1

Van Der Vieren, M., Crowe, D. T., Hoekstra, D., Vazeux, R., Hoffman, P. A., Grayson, M. H., Bochner, B. S., Gallatin, W. M. & Staunton, D. E., Aug 15 1999, In : Journal of Immunology. 163, 4, p. 1984-1990 7 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Integrins
Leukocytes
Binding Sites
Intercellular Adhesion Molecule-1
15 Citations (Scopus)

αdβ2 integrin is a ligand for vascular cell adhesion molecule-1

Grayson, M. H., Van Der Vieren, M., Sterbinsky, S. A., Gallantin, W. M., Hoffman, P., Staunton, D. & Bochner, B. S., Jan 1 1999, In : International Archives of Allergy and Immunology. 118, 2-4, p. 263-264 2 p.

Research output: Contribution to journalArticle

Cytoadhesin Receptors
CD11 Antigens
Integrin alpha Chains
Vascular Cell Adhesion Molecule-1
CHO Cells
1998
8 Citations (Scopus)

Altered expression of CD11b and CD62L after cross-linking of CD45 isoforms on human eosinophils

Matsumoto, K., Bochner, B. S., Wakiguchi, H. & Kurashige, T., Sep 1 1998, In : International archives of allergy and immunology. 117, SUPPL. 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

Eosinophils
Protein Isoforms
Monoclonal Antibodies
Flow Cytometry
Protein Tyrosine Phosphatases
27 Citations (Scopus)

Antagonism of selectin-dependent adhesion of human eosinophils and neutrophils by glycomimetics and oligosaccharide compounds

Kim, M. K., Brandley, B. K., Anderson, M. B. & Bochner, B. S., Jan 1 1998, In : American Journal of Respiratory Cell and Molecular Biology. 19, 5, p. 836-841 6 p.

Research output: Contribution to journalArticle

Selectins
Oligosaccharides
Eosinophils
Neutrophils
Adhesion
37 Citations (Scopus)
Small Cell Lung Carcinoma
Integrins
Cell Communication
Agar
Organism Cloning
73 Citations (Scopus)

CD44 and CD69 represent different types of cell-surface activation markers for human eosinophils

Matsumoto, K., Appiah-Pippim, J., Schleimer, R. P., Bickel, C. A., Beck, L. A. & Bochner, B. S., Jan 1 1998, In : American journal of respiratory cell and molecular biology. 18, 6, p. 860-866 7 p.

Research output: Contribution to journalArticle

Eosinophils
Chemical activation
Granulocyte-Macrophage Colony-Stimulating Factor
Interleukin-3
Interleukin-5
14 Citations (Scopus)

Intranasal beclomethasone reduces allergen-induced symptoms and superficial mucosal eosinophilia without affecting submucosal inflammation

Baroody, F. M., Rouadi, P., Driscoll, P. V., Bochner, B. S. & Naclerio, R. M., Dec 1 1998, In : American Journal of Respiratory and Critical Care Medicine. 157, 3 PART I, p. 899-906 8 p.

Research output: Contribution to journalArticle

Beclomethasone
Eosinophilia
Eosinophils
Allergens
Inflammation
124 Citations (Scopus)

In vitro regulation of FcεRIα expression on human basophils by IgE antibody

MacGlashan, D., McKenzie-White, J., Chichester, K., Bochner, B. S., Davis, F. M., Schroeder, J. T. & Lichtenstein, L. M., Mar 1 1998, In : Blood. 91, 5, p. 1633-1643 11 p.

Research output: Contribution to journalArticle

Basophils
Immunoglobulin E
Up-Regulation
Antibodies
Flow cytometry
72 Citations (Scopus)

Lipopolysaccharide-induced leukocyte rolling and adhesion in the rat mesenteric microcirculation: Regulation by glucocorticoids and role of cytokines

Davenpeck, K. L., Zagorski, J., Schleimer, R. P. & Bochner, B. S., Dec 15 1998, In : Journal of Immunology. 161, 12, p. 6861-6870 10 p.

Research output: Contribution to journalArticle

Leukocyte Rolling
Microcirculation
Glucocorticoids
Lipopolysaccharides
Leukocytes
3 Citations (Scopus)

New concepts in the pathogenesis and treatment of allergic asthma

Grayson, M. H. & Bochner, B. S., Sep 1 1998, In : Mount Sinai Journal of Medicine. 65, 4, p. 246-256 11 p.

Research output: Contribution to journalReview article

Asthma
Immunoglobulin E
Leukotriene Antagonists
Therapeutics
Chemokines

Prednisone administration alters basal and endotoxin-stimulated expression of adhesion molecules on human neutrophils

Davenpeck, K. L. & Bochner, B. S., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

prednisone
endotoxins
Prednisone
Endotoxins
adhesion
46 Citations (Scopus)

Rat neutrophils express α4 and β1 integrins and bind to vascular cell adhesion molecule-1 (VCAM-1) and mucosal addressin cell adhesion molecule-1 (MAdCAM-1)

Davenpeck, K. L., Sterbinsky, S. A. & Bochner, B. S., Apr 1 1998, In : Blood. 91, 7, p. 2341-2346 6 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Cell Adhesion Molecules
Integrins
Rats
Neutrophils
48 Citations (Scopus)
Anti-Allergic Agents
Inflammation
Cell Adhesion Molecules
Therapeutics
98 Citations (Scopus)

αdβ2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM-1)

Grayson, M. H., Van Der Vieren, M., Sterbinsky, S. A., Gallatin, W. M., Hoffman, P. A., Staunton, D. E. & Bochner, B. S., Dec 7 1998, In : Journal of Experimental Medicine. 188, 11, p. 2187-2191 5 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Eosinophils
Integrins
Interleukin-5
Ligands
12 Citations (Scopus)

β1 integrin-dependent binding of Jurkat cells to fibronectin is regulated by a serine-threonine phosphatase

Seminario, M. C., Sterbinsky, S. A. & Bochner, B. S., Jan 1 1998, In : Journal of Leukocyte Biology. 64, 6, p. 753-758 6 p.

Research output: Contribution to journalArticle

Jurkat Cells
Phosphoprotein Phosphatases
Fibronectins
Integrins
Okadaic Acid
1997
82 Citations (Scopus)

Antibody to VLA-4, but not to L-selectin, protects neuronal M2 muscarinic receptors in antigen-challenged guinea pig airways

Fryer, A. D., Costello, R. W., Yost, B. L., Lobb, R. R., Tedder, T. F., Steeber, D. A. & Bochner, B. S., Apr 15 1997, In : Journal of Clinical Investigation. 99, 8, p. 2036-2044 9 p.

Research output: Contribution to journalArticle

Muscarinic M2 Receptors
Integrin alpha4beta1
L-Selectin
Eosinophils
Guinea Pigs
39 Citations (Scopus)

Cellular adhesion and its antagonism

Bochner, B. S., Jan 1 1997, In : Journal of Allergy and Clinical Immunology. 100, 5, p. 581-585 5 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

Cutaneous injection of RANTES causes eosinophil recruitment: Comparison of nonallergic and allergic human subjects

Beck, L. A., Dalke, S., Leiferman, K. M., Bickel, C. A., Hamilton, R., Rosen, H., Bochner, B. S. & Schleimer, R. P., Dec 1 1997, In : Journal of Immunology. 159, 6, p. 2962-2972 11 p.

Research output: Contribution to journalArticle

Chemokine CCL5
Eosinophils
Skin
Injections
Chemotactic Factors
79 Citations (Scopus)
Leukotriene Receptors
P-Selectin
Endothelial Cells
Leukotriene C4
Leukotriene D4

Detection of the chemokine RANTES and ende thelial adhesions molecules in nasal polyps

Beck, L. A., Stellato, C., Beall, L. D., Schall, T. J., Leopold, D., Bickel, C. A., Baroody, F., Bochner, B. S. & Schleimer, R. P., Dec 1 1997, In : American Journal of Rhinology. 11, 1, 1 p.

Research output: Contribution to journalArticle

Nasal Polyps
Chemokine CCL5
Chemokines
2 Citations (Scopus)
Microcirculation
L-Selectin
P-Selectin
lipopolysaccharides
Lipopolysaccharides
663 Citations (Scopus)

Down-Regulation of FcεRI Expression on Human Basophils during in Vivo Treatment of Atopic Patients with Anti-IgE Antibody

MacGlashan, D. W., Bochner, B. S., Adelman, D. C., Jardieu, P. M., Togias, A., McKenzie-White, J., Sterbinsky, S. A., Hamilton, R. G. & Lichtenstein, L. M., Feb 1 1997, In : Journal of Immunology. 158, 3, p. 1438-1445 8 p.

Research output: Contribution to journalArticle

Basophils
Immunoglobulin E
Down-Regulation
Therapeutics
Dermatophagoides farinae
18 Citations (Scopus)

Expression and Function of β1 Integrins on Human Eosinophils

Seminario, M. C. & Bochner, B. S., Jan 1 1997, In : Memorias do Instituto Oswaldo Cruz. 92 SUPPL. 2, p. 157-164 8 p.

Research output: Contribution to journalArticle

Eosinophils
Integrins
Vascular Cell Adhesion Molecule-1
Integrin alpha4beta1
Endothelial Cells
42 Citations (Scopus)

P- and L-Selectin Mediate Distinct but Overlapping Functions in Endotoxin-Induced Leukocyte-Endothelial Interactions in the Rat Mesenteric Microcirculation

Davenpeck, K. L., Steeber, D. A., Tedder, T. F. & Bochner, B. S., Aug 15 1997, In : Journal of Immunology. 159, 4, p. 1977-1986 10 p.

Research output: Contribution to journalArticle

Leukocyte Rolling
L-Selectin
P-Selectin
Microcirculation
Endotoxins
65 Citations (Scopus)
Alveolar Macrophages
Monocytes
Asthma
Inflammation
Dimercaprol

Phenotypic and functional characteristics of adhesion molecules on human basophils

Saini, SS., Matsumoto, K. & Bochner, BS., 1997, Adhesion Molecules in Allergic Disease. Bochner, BS. (ed.). New York: Marcel Dekker, p. 129-138

Research output: Chapter in Book/Report/Conference proceedingChapter

108 Citations (Scopus)
Vascular Cell Adhesion Molecule-1
Intercellular Adhesion Molecule-1
Demonstrations
Adhesion
Epithelial Cells
158 Citations (Scopus)

Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines

Stellato, C., Collins, P., Ponath, P. D., Soler, D., Newman, W., La Rosa, G., Li, H., White, J., Schwiebert, L. M., Bickel, C., Liu, M., Bochner, B. S., Williams, T. & Schleimer, R. P., Mar 1 1997, In : Journal of Clinical Investigation. 99, 5, p. 926-936 11 p.

Research output: Contribution to journalArticle

Monocyte Chemoattractant Proteins
CC Chemokines
Eosinophils
Messenger RNA
Epithelial Cells
55 Citations (Scopus)

Regulation of α4 integrin-mediated adhesion of human eosinophils to fibronectin and vascular cell adhesion molecule-1

Matsumoto, K., Sterbinsky, S. A., Bickel, C. A., Zhou, D. F. H., Kovach, N. L. & Bochner, B. S., Jan 1 1997, In : Journal of Allergy and Clinical Immunology. 99, 5, p. 648-656 9 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Fibronectins
Eosinophils
Integrins
Monoclonal Antibodies
56 Citations (Scopus)

Serum ige level drives basophil and mast cell ige receptor display

MacGlashan, D. W., Bochner, B. S., Adelman, D. C., Jardieu, P. M., Togias, A. & Lichtenstein, L. M., Jan 1 1997, In : International Archives of Allergy and Immunology. 113, 1-3, p. 45-47 3 p.

Research output: Contribution to journalArticle

IgE Receptors
Basophils
Histamine Release
Mast Cells
Immunoglobulin E
19 Citations (Scopus)

Studies of cell adhesion and flow cytometric analyses of degranulation, surface phenotype, and viability using human eosinophils, basophils, and mast cells

Bochner, B. S., Sterbinsky, S. A., Saini, S. A., Columbo, M. & Macglashan, D. W., Jan 1 1997, In : Methods: A Companion to Methods in Enzymology. 13, 1, p. 61-68 8 p.

Research output: Contribution to journalArticle

Basophils
Cell adhesion
Eosinophils
Mast Cells
Cell Adhesion
1996

CD44 surface expression is increased on human eosinophils activated in vitro and in vivo

Bochner, B. S., Matsiimoto, K., Appiah-Pippim, J., Schleimer, R. P. & Beck, L. A., Jan 1 1996, In : Journal of Investigative Medicine. 44, 3

Research output: Contribution to journalArticle

Flow cytometry
Centrifugation
Surface Antigens
Eosinophils
Intercellular Signaling Peptides and Proteins

Cough, shortness of breath, and eosinophilia in a 68-year-old man

Goldman, M. H., Bochner, B. S. & Essayan, D. M., Jan 1 1996, In : Annals of Allergy, Asthma and Immunology. 77, 3, p. 177-183 7 p.

Research output: Contribution to journalArticle

Eosinophilia
Cough
Dyspnea
32 Citations (Scopus)

Counter-receptors on human basophils for endothelial cell adhesion molecules

Bochner, B. S., Sterbinsky, S. A., Briskin, M., Saini, S. S. & MacGlashan, D. W., Jul 15 1996, In : Journal of Immunology. 157, 2, p. 844-850 7 p.

Research output: Contribution to journalArticle

Basophils
Integrins
E-Selectin
Vascular Cell Adhesion Molecule-1
Cell Adhesion Molecules
94 Citations (Scopus)

Detection of the chemokine RANTES and endothelial adhesion molecules in nasal polyps

Beck, L. A., Stellate, C., Beall, L. D., Schall, T. J., Leopold, D., Bickel, C. A., Baroody, F., Bochner, B. S. & Schleimer, R. P., Jan 1 1996, In : Journal of Allergy and Clinical Immunology. 98, 4, p. 766-780 15 p.

Research output: Contribution to journalArticle

Nasal Polyps
Chemokine CCL5
Vascular Cell Adhesion Molecule-1
Chemokines
Eosinophils

EINWANDERUNG VON T-HELFER-GEDACHTNISZELLEN WAHREND DER IGE-ABHANGIGEN SPATREAKTION IN DIE MENSCHLICHE HAUT. IN-VIVO-UNTERSUCHUNG NACH ALLERGENPROVOKATION IM HAUTBLASENMODELL

Translated title of the contribution: Migration of T helper memory cells during IgE dependent late phase response in human skin. In vivo study after allergen challenge in skin chamber modelWerfel, S., Massey, W., Lichtenstein, L. M. & Bochner, B. S., Jan 1 1996, In : Allergologie. 19, 4, p. 187-189 3 p.

Research output: Contribution to journalArticle

HLA-DR Antigens
Helper-Inducer T-Lymphocytes
Allergens
Immunoglobulin E
Skin
23 Citations (Scopus)

Functional Regulation of β1 Integrins on Human Eosinophils by Divalent Cations and Cytokines

Werfel, S. J., Yednock, T. A., Matsumoto, K., Sterbinsky, S. A., Schleimer, R. P. & Bochner, B. S., Jan 1 1996, In : American journal of respiratory cell and molecular biology. 14, 1, p. 44-52 9 p.

Research output: Contribution to journalArticle

Divalent Cations
Eosinophils
Integrins
Interleukin-5
Monoclonal Antibodies
1 Citation (Scopus)
endotoxins
glucocorticoids
Endotoxins
Glucocorticoids
Rats
137 Citations (Scopus)

Glucocorticosteroid inhibition of cytokine production: Relevance to antiallergic actions

Schwiebert, L. A., Beck, L. A., Stellato, C., Bickel, C. A., Bochner, B. S. & Schleimer, R. P., Jan 1 1996, In : Journal of Allergy and Clinical Immunology. 97, 1 II, p. 143-152 10 p.

Research output: Contribution to journalArticle

Anti-Allergic Agents
Glucocorticoids
Cytokines
Eosinophils
Endothelium