• Source: Scopus
1990 …2021

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Personal profile

Research Interests

Cell-cell adhesion in health and disease

We are interested in how cells stick to each other, what constitutes dynamic versus static adhesion at the molecular level, and how the state of cell-cell adhesion is interpreted by the nucleus to control gene expression and cellular differentiation. These processes are highly relevant to human health and disease because the proteins comprising the major macromolecular adhesion complex on cells (known as the cadherin/catenin complex) are associated with numerous diseases ranging from proliferative/invasive conditions like cancer and fibrosis to chronic conditions such as asthma. We collaborate with Drosophila geneticists, biochemists/ crystallographers, biophysicists and physician scientists with access to patient sample data sets for these investigations.

Expertise related to UN Sustainable Devlopment Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD, Yale University

… → 1994

Research interests

  • Cancer Biology
  • Cell Adhesion Mechanisms
  • Cell Biology
  • Fibrosis
  • Gene Regulation
  • Lung Cancer / Chest Cancer
  • Respiratory Diseases
  • Signal Transduction

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