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Research Output 1990 2019

2019

Macrophages as a Source and Recipient of Wnt Signals

Malsin, E. S., Kim, S., Lam, A. P. & Gottardi, C., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalReview article

Open Access
Macrophages
Debridement
Lenses
Stem Cells
Phenotype
22 Citations (Scopus)

Single-cell transcriptomic analysis of human lung provides insights into the pathobiology of pulmonary fibrosis

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C. I., Ren, Z., Verma, R., Abdala-Valencia, H., Nam, K., Chi, M., Han, S. H., Gonzalez-Gonzalez, F. J., Soberanes, S., Watanabe, S., Williams, K. J. N., Flozak, A. S. & 29 others, Nicholson, T. T., Morgan, V. K., Winter, D. R., Hinchcliff, M., Hrusch, C. L., Guzy, R. D., Bonham, C. A., Sperling, A. I., Bag, R., Hamanaka, R. B., Mutlu, G. M., Yeldandi, A. V., Marshall, S. A., Shilatifard, A., Amaral, L. A. N., Perlman, H. R., Sznajder, J. I., Christine Argento, A., Gillespie, C. T., Dematte, J., Jain, M., Singer, B., Ridge, K. M., Lam, A. P., Bharat, A., Bhorade, S. M., Gottardi, C., Budinger, GR. S. & Misharin, A., Jun 15 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 12, p. 1517-1536 20 p.

Research output: Contribution to journalArticle

Open Access
Single-Cell Analysis
Pulmonary Fibrosis
Lung
RNA Sequence Analysis
Alveolar Macrophages
2018
7 Citations (Scopus)

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions

Ishiyama, N., Sarpal, R., Wood, M. N., Barrick, S. K., Nishikawa, T., Hayashi, H., Kobb, A. B., Flozak, A. S., Yemelyanov, A., Fernandez-Gonzalez, R., Yonemura, S., Leckband, D. E., Gottardi, C. J., Tepass, U. & Ikura, M., Dec 1 2018, In : Nature communications. 9, 1, 5121.

Research output: Contribution to journalArticle

Adherens Junctions
Catenins
Actins
helices
Cadherins
2 Citations (Scopus)

αT-catenin: A developmentally dispensable, disease-linked member of the α-catenin family

Chiarella, S. E., Rabin, E. E., Ostilla, L. A., Flozak, A. S. & Gottardi, C., Apr 3 2018, In : Tissue Barriers. 6, 2, e1463896.

Research output: Contribution to journalArticle

Catenins
Microfilament Proteins
Protein Subunits
Cadherins
Actin Cytoskeleton
2017
18 Citations (Scopus)
Epithelial-Mesenchymal Transition
Asthma
Transcriptome
Epithelial Cells
Insulin
3 Citations (Scopus)

Cardiomyocytes of the heart and pulmonary veins: Novel contributors to asthma?

Folmsbee, S. S. & Gottardi, C., Nov 1 2017, In : American journal of respiratory cell and molecular biology. 57, 5, p. 512-518 7 p.

Research output: Contribution to journalReview article

Pulmonary Veins
Cardiac Myocytes
Asthma
Genes
Steroids
14 Citations (Scopus)

Lrp5/b-Catenin signaling controls lung macrophage differentiation and inhibits resolution of fibrosis

Sennello, J. A., Misharin, A., Flozak, A. S., Berdnikovs, S., Cheresh, P., Varga, J., Kamp, D. W., Budinger, GR. S., Gottardi, C. & Lam, A. P., Feb 1 2017, In : American journal of respiratory cell and molecular biology. 56, 2, p. 191-201 11 p.

Research output: Contribution to journalArticle

Low Density Lipoprotein Receptor-Related Protein-5
Catenins
Macrophages
Fibrosis
Lung
128 Citations (Scopus)

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

Misharin, A. V., Morales-Nebreda, L., Reyfman, P. A., Cuda, C. M., Walter, J. M., McQuattie-Pimentel, A. C., Chen, C. I., Anekalla, K. R., Joshi, N., Williams, K. J. N., Abdala-Valencia, H., Yacoub, T. J., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Gates, K., Lam, A. P., Nicholson, T. T., Homan, P. J., Soberanes, S. & 23 others, Dominguez, S., Morgan, V. K., Saber, R., Shaffer, A., Hinchcliff, M., Marshall, S. A., Bharat, A., Berdnikovs, S., Bhorade, S. M., Bartom, E. T., Morimoto, R. I., Balch, W. E., Sznajder, J. I., Chandel, N. S., Mutlu, G. M., Jain, M., Gottardi, C. J., Singer, B. D., Ridge, K. M., Bagheri, N., Shilatifard, A., Budinger, G. R. S. & Perlman, H., Aug 1 2017, In : Journal of Experimental Medicine. 214, 8, p. 2387-2404 18 p.

Research output: Contribution to journalArticle

Alveolar Macrophages
Fibrosis
Macrophages
Lung
Monocytes
8 Citations (Scopus)

Nuclear α-catenin mediates the DNA damage response via β-catenin and nuclear actin

Serebryannyy, L. A., Yemelyanov, A., Gottardi, C. & de Lanerolle, P., May 15 2017, In : Journal of cell science. 130, 10, p. 1717-1729 13 p.

Research output: Contribution to journalArticle

Catenins
DNA Damage
Actins
Nuclear Proteins
Cell Adhesion
8 Citations (Scopus)

α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion

Wood, M. N., Ishiyama, N., Singaram, I., Chung, C. M., Flozak, A. S., Yemelyanov, A., Ikura, M., Cho, W. & Gottardi, C., Nov 1 2017, In : Journal of Cell Biology. 216, 11, p. 3767-3783 17 p.

Research output: Contribution to journalArticle

Catenins
Phosphatidylinositols
Membranes
Cadherins
Pseudopodia
2016
8 Citations (Scopus)

Adiponectin inhibits Wnt co-receptor, Lrp6, phosphorylation and β-catenin signaling

Reinke, L., Lam, A. P., Flozak, A. S., Varga, J. & Gottardi, C., Feb 12 2016, In : Biochemical and Biophysical Research Communications. 470, 3, p. 606-612 7 p.

Research output: Contribution to journalArticle

Wnt Receptors
Catenins
Phosphorylation
Adiponectin
Chemical activation

A simple method to assess abundance of the β-Catenin signaling pool in cells

Flozak, A. S., Lam, A. P. & Gottardi, C. J., Jan 1 2016, Methods in Molecular Biology. Humana Press Inc, p. 49-60 12 p. (Methods in Molecular Biology; vol. 1481).

Research output: Chapter in Book/Report/Conference proceedingChapter

Catenins
Cadherins
Transducers
57 Citations (Scopus)

Beyond β-catenin: Prospects for a larger catenin network in the nucleus

McCrea, P. D. & Gottardi, C., Jan 1 2016, In : Nature Reviews Molecular Cell Biology. 17, 1, p. 55-64 10 p.

Research output: Contribution to journalReview article

Catenins
Intercellular Junctions
Vinculin
Microfilament Proteins
Cadherins
25 Citations (Scopus)

Persistent nuclear actin filaments inhibit transcription by RNA polymerase II

Serebryannyy, L. A., Parilla, M., Annibale, P., Cruz, C. M., Laster, K., Gratton, E., Kudryashov, D., Kosak, S. T., Gottardi, C. J. & de Lanerolle, P., Jan 1 2016, In : Journal of cell science. 129, 18, p. 3412-3425 14 p.

Research output: Contribution to journalArticle

RNA Polymerase II
Actin Cytoskeleton
Actins
Cell Proliferation
6 Citations (Scopus)

The cardiomyocyte protein αT-catenin contributes to asthma through regulating pulmonary vein inflammation

Folmsbee, S. S., Budinger, GR. S., Bryce, P. J. & Gottardi, C., Jul 1 2016, In : Journal of Allergy and Clinical Immunology. 138, 1, p. 123-129.e2

Research output: Contribution to journalArticle

Catenins
Pulmonary Veins
Cardiac Myocytes
Pneumonia
Asthma
32 Citations (Scopus)

Wnt-induced deubiquitination FoxM1 ensures nucleus β-catenin transactivation

Chen, Y., Li, Y., Xue, J., Gong, A., Yu, G., Zhou, A., Lin, K., Zhang, S., Zhang, N., Gottardi, C. & Huang, S., Mar 15 2016, In : EMBO Journal. 35, 6, p. 668-684 17 p.

Research output: Contribution to journalArticle

Catenins
Transcriptional Activation
beta Catenin
Phosphorylation
Cell Proliferation
8 Citations (Scopus)

αT-catenin in restricted brain cell types and its potential connection to autism

Folmsbee, S. S., Wilcox, D. R., Tyberghein, K., De Bleser, P., Tourtellotte, W. G., Hengel, J. V., van Roy, F. & Gottardi, C., Jan 1 2016, In : Journal of Molecular Psychiatry. 4, 1, 2.

Research output: Contribution to journalArticle

Catenins
Autistic Disorder
Cats
Brain
Adherens Junctions
2015
41 Citations (Scopus)

Nuclear signaling from cadherin adhesion complexes

McCrea, P. D., Maher, M. T. & Gottardi, C., Jan 1 2015, Current Topics in Developmental Biology. Academic Press Inc., p. 129-196 68 p. (Current Topics in Developmental Biology; vol. 112).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cadherins
Wnt Receptors
Catenins
Cell Adhesion
Protein-Tyrosine Kinases
11 Citations (Scopus)

Structural determinants of the mechanical stability of α-Catenin

Li, J., Newhall, J., Ishiyama, N., Gottardi, C., Ikura, M., Leckband, D. E. & Tajkhorshid, E., Jul 31 2015, In : Journal of Biological Chemistry. 290, 31, p. 18890-18903 14 p.

Research output: Contribution to journalArticle

Catenins
Mechanical stability
Cell adhesion
Molecular Dynamics Simulation
Cell Adhesion
10 Citations (Scopus)

The cardiac protein αT-catenin contributes to chemical-induced asthma

Folmsbee, S. S., Morales-Nebreda, L., Van Henge, J., Tyberghein, K., Van Roy, F., Budinger, G. R. S., Bryce, P. J. & Gottardi, C. J., Jan 1 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 308, 3, p. L253-L258

Research output: Contribution to journalArticle

Catenins
Cats
Asthma
Toluene 2,4-Diisocyanate
Knockout Mice
4 Citations (Scopus)

The Increase in Maternal Expression of axin1 and axin2 Contribute to the Zebrafish Mutant Ichabod Ventralized Phenotype

Valenti, F., Ibetti, J., Komiya, Y., Baxter, M., Lucchese, A. M., Derstine, L., Covaciu, C., Rizzo, V., Vento, R., Russo, G., Macaluso, M., Cotelli, F., Castiglia, D., Gottardi, C., Habas, R., Giordano, A. & Bellipanni, G., Mar 1 2015, In : Journal of Cellular Biochemistry. 116, 3, p. 418-430 13 p.

Research output: Contribution to journalArticle

Catenins
Zebrafish
Mothers
Phenotype
Embryonic Structures
22 Citations (Scopus)

α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism

Escobar, D. J., Desai, R., Ishiyama, N., Folmsbee, S. S., Novak, M. N., Flozak, A. S., Daugherty, R. L., Mo, R., Nanavati, D., Sarpal, R., Leckband, D., Ikura, M., Tepass, U. & Gottardi, C., Jan 1 2015, In : Journal of cell science. 128, 6, p. 1150-1165 16 p.

Research output: Contribution to journalArticle

Catenins
Phosphotransferases
Phosphorylation
Cadherins
Drosophila
2014
27 Citations (Scopus)

E-cadherin phosphorylation occurs during its biosynthesis to promote its cell surface stability and adhesion

McEwen, A. E., Maher, M. T., Mo, R. & Gottardi, C., Jan 1 2014, In : Molecular biology of the cell. 25, 16, p. 2365-2374 10 p.

Research output: Contribution to journalArticle

Cadherins
Catenins
Phosphorylation
Serine
Endocytosis
38 Citations (Scopus)

Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth

Ono, M., Yin, P., Navarro, A., Moravek, M. B., Coon V, J. S., Druschitz, S. A., Gottardi, C. & Bulun, S. E., Jan 1 2014, In : Fertility and Sterility. 101, 5

Research output: Contribution to journalArticle

Catenins
Leiomyoma
Niclosamide
Growth
Uterine Myomectomy
55 Citations (Scopus)

Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis

Lam, A. P., Herazo-Maya, J. D., Sennello, J. A., Flozak, A. S., Russell, S. R., Mutlu, G. M., Budinger, GR. S., DasGupta, R., Varga, J., Kaminski, N. & Gottardi, C., Jul 15 2014, In : American journal of respiratory and critical care medicine. 190, 2, p. 185-195 11 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Transforming Growth Factors
Fibrosis
Catenins
Lung
66 Citations (Scopus)

α-Catenin cytomechanics - role in cadherin-dependent adhesion and mechanotransduction

Barry, A. K., Tabdili, H., Muhamed, I., Wu, J., Shashikanth, N., Gomez, G. A., Yap, A. S., Gottardi, C. J., De Rooij, J., Wang, N. & Leckband, D. E., 2014, In : Journal of cell science. 127, 8, p. 1779-1791 13 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Actins
Vinculin
Traction
24 Citations (Scopus)

α-Catenin is an inhibitor of transcription

Daugherty, R. L., Serebryannyy, L., Yemelyanov, A., Flozak, A. S., Yu, H. J., Kosak, S. T., De Lanerolle, P. & Gottardi, C., Jan 1 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 14, p. 5260-5265 6 p.

Research output: Contribution to journalArticle

Catenins
Cats
Actins
TCF Transcription Factors
Microfilament Proteins
2013
17 Citations (Scopus)

Considerations for targeting β-catenin signaling in fibrosis

Gottardi, C. & Königshoff, M., Mar 15 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 6, p. 566-568 3 p.

Research output: Contribution to journalEditorial

Pulmonary Alveoli
Pulmonary Fibrosis
beta Catenin
Lung Injury
Fibrosis

Fat in fibrosis

Lam, A. P. & Gottardi, C. J., Nov 15 2013, In : American journal of respiratory and critical care medicine. 188, 10, p. 1268-1269 2 p.

Research output: Contribution to journalLetter

White Adipocytes
Cell Differentiation
Fibrosis
Fibroblasts
Fats
4 Citations (Scopus)

ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours

Campos, M. L., Sánchez-Arévalo Lobo, V. J., Rodolosse, A., Gottardi, C., Mafficini, A., Beghelli, S., Scardoni, M., Bassi, C., Scarpa, A. & Real, F. X., May 1 2013, In : Biochemical Journal. 451, 3, p. 395-405 11 p.

Research output: Contribution to journalArticle

Catenins
Tumors
Display devices
Pancreas
Acinar Cells

ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours (Biochemical Journal (2013) 451, (395-405))

Campos, M. L., Sánchez-Arévalo Lobo, V. J., Rodolosse, A., Gottardi, C. J., Mafficini, A., Beghelli, S., Scardoni, M., Bassi, C., Scarpa, A. & Real, F. X., Jul 1 2013, In : Biochemical Journal. 453, 1, 1 p.

Research output: Contribution to journalComment/debate

Tumors
Display devices
145 Citations (Scopus)

Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development

Hamanaka, R. B., Glasauer, A., Hoover, P., Yang, S., Blatt, H., Mullen, A. R., Getsios, S., Gottardi, C. J., DeBerardinis, R. J., Lavker, R. M. & Chandel, N. S., Feb 5 2013, In : Science Signaling. 6, 261, ra8.

Research output: Contribution to journalArticle

Hair Follicle
Keratinocytes
Reactive Oxygen Species
Mitochondria
Catenins
71 Citations (Scopus)

Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth

Ono, M., Yin, P., Navarro, A., Moravek, M. B., Coon V, J. S., Druschitz, S. A., Serna, V. A., Qiang, W., Brooks, D. C., Malpani, S. S., Ma, J., Ercan, C. M., Mittal, N., Monsivais, D., Dyson, M. T., Yemelyanov, A., Maruyama, T., Chakravarti, D., Kim, J. J., Kurita, T. & 2 others, Gottardi, C. J. & Bulun, S. E., Oct 15 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 17053-17058 6 p.

Research output: Contribution to journalArticle

Catenins
Neoplastic Stem Cells
Leiomyoma
Side-Population Cells
Growth
2012
25 Citations (Scopus)

Fibrosis in systemic sclerosis: Common and unique pathobiology

Bhattacharyya, S., Wei, J., Tourtellotte, W. G., Hinchcliff, M., Gottardi, C. G. & Varga, J., Jun 6 2012, In : Fibrogenesis and Tissue Repair. 5, SUPPL.1, S18.

Research output: Contribution to journalArticle

Systemic Scleroderma
Peroxisome Proliferator-Activated Receptors
Fibrosis
Drug Repositioning
Fibroblasts

Signaling from adherens junctions

McEwen, A. E., Escobar, D. J. & Gottardi, C. J., 2012, The Adherens Junction. Harris, T. (ed.). New York: Elsevier

Research output: Chapter in Book/Report/Conference proceedingChapter

25 Citations (Scopus)

Signaling from the adherens junction

McEwen, A. E., Escobar, D. E. & Gottardi, C., Jan 1 2012, In : Sub-Cellular Biochemistry. 60, p. 171-196 26 p.

Research output: Contribution to journalArticle

Adherens Junctions
Cadherins
Adhesion
Tissue
Catenins
13 Citations (Scopus)

UVB radiation-induced β-catenin signaling is enhanced by COX-2 expression in keratinocytes

Smith, K. A., Tong, X., Abu-Yousif, A. O., Mikulec, C. C., Gottardi, C., Fischer, S. M. & Pelling, J. C., Sep 1 2012, In : Molecular Carcinogenesis. 51, 9, p. 734-745 12 p.

Research output: Contribution to journalArticle

Catenins
Cyclooxygenase 2
Keratinocytes
Radiation
Skin
113 Citations (Scopus)

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

Wei, J., Fang, F., Lam, A. P., Sargent, J. L., Hamburg, E., Hinchcliff, M. E., Gottardi, C. J., Atit, R., Whitfield, M. L. & Varga, J., Aug 1 2012, In : Arthritis and rheumatism. 64, 8, p. 2734-2745 12 p.

Research output: Contribution to journalArticle

Catenins
Systemic Scleroderma
Biopsy
Adipogenesis
Wnt Signaling Pathway
2011
128 Citations (Scopus)

Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma?

Wei, J., Melichian, D., Komura, K., Hinchcliff, M. E., Lam, A. P., Lafyatis, R., Gottardi, C., MacDougald, O. A. & Varga, J., Jun 1 2011, In : Arthritis and rheumatism. 63, 6, p. 1707-1717 11 p.

Research output: Contribution to journalArticle

Fibrosis
Transgenic Mice
Skin
Systemic Scleroderma
Fibroblasts
36 Citations (Scopus)

Integrin regulation of β-catenin signaling in ovarian carcinoma

Burkhalter, R. J., Symowicz, J., Hudson, L. G., Gottardi, C. & Stack, M. S., Jul 1 2011, In : Journal of Biological Chemistry. 286, 26, p. 23467-23475 9 p.

Research output: Contribution to journalArticle

Catenins
Integrins
Cadherins
Carcinoma
Chemical activation
27 Citations (Scopus)

Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin-β-catenin

Mirkovic, I., Gault, W. J., Rahnama, M., Jenny, A., Gaengel, K., Bessette, D., Gottardi, C., Verheyen, E. M. & Mlodzik, M., Jun 1 2011, In : Nature Structural and Molecular Biology. 18, 6, p. 665-672 8 p.

Research output: Contribution to journalArticle

Catenins
Cell Polarity
Cadherins
Phosphotransferases
Cell Movement
95 Citations (Scopus)

Nuclear β-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation

Lam, A. P., Flozak, A. S., Russell, S. R., Wei, J., Jain, M., Mutlu, G. M., Budinger, GR. S., Feghali-Bostwick, C. A., Varga, J. & Gottardi, C., Nov 1 2011, In : American journal of respiratory cell and molecular biology. 45, 5, p. 915-922 8 p.

Research output: Contribution to journalArticle

Catenins
Pulmonary Fibrosis
Systemic Scleroderma
Fibroblasts
Lung
7 Citations (Scopus)

Regenerative pathways and emphysema: A new paradigm?

Lam, A. P., Gottardi, C. & Tuder, R., Mar 15 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 6, p. 688-690 3 p.

Research output: Contribution to journalEditorial

Wnt Proteins
Animal Disease Models
Pulmonary Emphysema
Emphysema
beta Catenin
17 Citations (Scopus)

Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis

Zhou, Q., Pardo, A., Königshoff, M., Eickelberg, O., Budinger, GR. S., Thavarajah, K., Gottardi, C., Jones, J., Varga, J., Selman, M., Sznajder, J. I., Raj, J. U. & Zhou, G., Sep 1 2011, In : FASEB Journal. 25, 9, p. 3032-3044 13 p.

Research output: Contribution to journalArticle

Fibroblasts
Fibrosis
Fibronectins
Integrins
Proteins
1 Citation (Scopus)
Transforming Growth Factor beta Receptors
Pulmonary Fibrosis
Sequence Deletion
Protein-Serine-Threonine Kinases
Bleomycin
101 Citations (Scopus)

β-catenin signaling: A novel mediator of fibrosis and potential therapeutic target

Lam, A. P. & Gottardi, C., Nov 1 2011, In : Current opinion in rheumatology. 23, 6, p. 562-567 6 p.

Research output: Contribution to journalReview article

Catenins
Fibrosis
Therapeutics
Wnt Signaling Pathway
Wounds and Injuries
2010
43 Citations (Scopus)

Nesprin-2 interacts with α-catenin and regulates Wnt signaling at the nuclear envelope

Neumann, S., Schneider, M., Daugherty, R. L., Gottardi, C., Eming, S. A., Beijer, A., Noegel, A. A. & Karakesisoglou, I., Nov 5 2010, In : Journal of Biological Chemistry. 285, 45, p. 34932-34938 7 p.

Research output: Contribution to journalArticle

Catenins
Nuclear Envelope
Cytoskeleton
Cell signaling
TCF Transcription Factors
104 Citations (Scopus)

Regulation of Wnt/β-catenin signaling by protein kinases

Verheyen, E. M. & Gottardi, C. J., Jan 1 2010, In : Developmental Dynamics. 239, 1, p. 34-44 11 p.

Research output: Contribution to journalReview article

Catenins
Wnt Signaling Pathway
Protein Kinases
Homeostasis
Neoplasms
67 Citations (Scopus)

β-Catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells

Flozak, A. S., Lam, A. P., Russell, S. R., Jain, M., Peled, O. N., Sheppard, K. A., Beri, R., Mutlu, G. M., Budinger, GR. S. & Gottardi, C., Jan 29 2010, In : Journal of Biological Chemistry. 285, 5, p. 3157-3167 11 p.

Research output: Contribution to journalArticle

TCF Transcription Factors
Alveolar Epithelial Cells
Catenins
Lung Injury
Chemical activation
62 Citations (Scopus)

β-catenin phosphorylated at serine 45 is spatially uncoupled from β-catenin phosphorylated in the GSK3 domain: Implications for signaling

Maher, M. T., Mo, R., Flozak, A. S., Peled, O. N. & Gottardi, C., Sep 10 2010, In : PloS one. 5, 4, e10184.

Research output: Contribution to journalArticle

Catenins
Threonine
serine
Serine
threonine