• 5809 Citations
1990 …2020

Research output per year

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Research Output

2010

Nesprin-2 interacts with α-catenin and regulates Wnt signaling at the nuclear envelope

Neumann, S., Schneider, M., Daugherty, R. L., Gottardi, C. J., Eming, S. A., Beijer, A., Noegel, A. A. & Karakesisoglou, I., Nov 5 2010, In : Journal of Biological Chemistry. 285, 45, p. 34932-34938 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Regulation of Wnt/β-catenin signaling by protein kinases

Verheyen, E. M. & Gottardi, C. J., Jan 1 2010, In : Developmental Dynamics. 239, 1, p. 34-44 11 p.

Research output: Contribution to journalReview article

111 Scopus citations

β-Catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells

Flozak, A. S., Lam, A. P., Russell, S., Jain, M., Peled, O. N., Sheppard, K. A., Beri, R., Mutlu, G. M., Budinger, G. R. S. & Gottardi, C. J., Jan 29 2010, In : Journal of Biological Chemistry. 285, 5, p. 3157-3167 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

β-catenin phosphorylated at serine 45 is spatially uncoupled from β-catenin phosphorylated in the GSK3 domain: Implications for signaling

Maher, M. T., Mo, R., Flozak, A. S., Peled, O. N. & Gottardi, C. J., 2010, In : PloS one. 5, 4, e10184.

Research output: Contribution to journalArticle

65 Scopus citations
2009

Activity of the β-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion

Maher, M. T., Flozak, A. S., Stocker, A. M., Chenn, A. & Gottardi, C. J., Jul 27 2009, In : Journal of Cell Biology. 186, 2, p. 219-228 10 p.

Research output: Contribution to journalArticle

93 Scopus citations

Issues associated with assessing nuclear localization of N-terminally unphosphorylated β-catenin with monoclonal antibody 8E7

Maher, M. T., Flozak, A. S., Hartsell, A. M., Russell, S., Beri, R., Peled, O. N. & Gottardi, C. J., Feb 2 2009, In : Biology Direct. 4, 5.

Research output: Contribution to journalArticle

19 Scopus citations

The terminal region of β-catenin promotes stability by shielding the armadillo repeats from the axin-scaffold destruction complex

Mo, R., Chew, T. L., Maher, M. T., Bellipanni, G., Weinberg, E. S. & Gottardi, C. J., Oct 9 2009, In : Journal of Biological Chemistry. 284, 41, p. 28222-28231 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2008

Cadherins and cancer: How does cadherin dysfunction promote tumor progression?

Jeanes, A., Gottardi, C. J. & Yap, A. S., Nov 24 2008, In : Oncogene. 27, 55, p. 6920-6929 10 p.

Research output: Contribution to journalReview article

549 Scopus citations

Molecular components of the adherens junction

Niessen, C. M. & Gottardi, C. J., Mar 1 2008, In : Biochimica et Biophysica Acta - Biomembranes. 1778, 3, p. 562-571 10 p.

Research output: Contribution to journalReview article

162 Scopus citations

Polycystin-1 C-terminal tail associates with β-catenin and inhibits canonical Wnt signaling

Lal, M., Song, X., Pluznick, J. L., Di Giovanni, V., Merrick, D. M., Rosenblum, N. D., Chauvet, V., Gottardi, C. J., Pei, Y. & Caplan, M. J., 2008, In : Human molecular genetics. 17, 20, p. 3105-3117 13 p.

Research output: Contribution to journalArticle

121 Scopus citations

Terminal Regions of β-Catenin Come into View

Gottardi, C. & Peifer, M., Mar 11 2008, In : Structure. 16, 3, p. 336-338 3 p.

Research output: Contribution to journalShort survey

20 Scopus citations

Tight Junctions in Simple and Stratified Epithelium

Gottardi, C. & Niessen, C. M., Apr 11 2008, Cell Junctions: Adhesion, Development, and Disease. Wiley-VCH Verlag GmbH & Co. KGaA, p. 217-233 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

VE-cadherin and β-catenin binding dynamics during histamine-induced endothelial hyperpermeability

Guo, M., Breslin, J. W., Wu, M. H., Gottardi, C. J. & Yuan, S. Y., Apr 2008, In : American Journal of Physiology - Cell Physiology. 294, 4, p. C977-C984

Research output: Contribution to journalArticle

47 Scopus citations
2007

Phospho-regulation of β-catenin adhesion and signaling functions

Daugherty, R. L. & Gottardi, C. J., Oct 2007, In : Physiology. 22, 5, p. 303-309 7 p.

Research output: Contribution to journalReview article

182 Scopus citations
2005

Terminating Wnt signals: A novel nuclear export mechanism targets activated β-catenin

Thorne, M. E. & Gottardi, C. J., Dec 5 2005, In : Journal of Cell Biology. 171, 5, p. 761-763 3 p.

Research output: Contribution to journalReview article

4 Scopus citations

When domestiques rebel: Kinesins, cadherins and neuronal proliferation

Gottardi, C., den Elzen, N. R. & Yap, A. S., May 1 2005, In : Nature Cell Biology. 7, 5, p. 445-447 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2004

Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes

Gottardi, C. J. & Gumbiner, B. M., Oct 25 2004, In : Journal of Cell Biology. 167, 2, p. 339-349 11 p.

Research output: Contribution to journalArticle

248 Scopus citations

Role for ICAT in β-catenin-dependent nuclear signaling and cadherin functions

Gottardi, C. J. & Gumbiner, B. M., Apr 1 2004, In : American Journal of Physiology - Cell Physiology. 286, 4 55-4

Research output: Contribution to journalArticle

63 Scopus citations
2001

Adhesion signaling: How β-catenin interacts with its partners

Gottardi, C. J. & Gumbiner, B. M., Oct 2 2001, In : Current Biology. 11, 19, p. R792-R794

Research output: Contribution to journalReview article

182 Scopus citations

A Dileucine Motif Targets E-cadherin to the Basolateral Cell Surface in Madin-Darby Canine Kidney and LLC-PK1 Epithelial Cells

Miranda, K. C., Khromykh, T., Christy, P., Le, T. L., Gottardi, C. J., Yap, A. S., Stow, J. L. & Teasdale, R. D., Jun 22 2001, In : Journal of Biological Chemistry. 276, 25, p. 22565-22572 8 p.

Research output: Contribution to journalArticle

135 Scopus citations

E-cadherin suppresses cellular transformation by inhibiting β-catenin signaling in an adhesion-independent manner

Gottardi, C. J., Wong, E. & Gumbiner, B. M., May 25 2001, In : Journal of Cell Biology. 153, 5, p. 1049-1059 11 p.

Research output: Contribution to journalArticle

429 Scopus citations
1999

A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes

Lecuit, M., Dramsi, S., Gottardi, C., Fedor-Chaiken, M., Gumbiner, B. & Cossart, P., Jul 15 1999, In : EMBO Journal. 18, 14, p. 3956-3963 8 p.

Research output: Contribution to journalArticle

337 Scopus citations
1998

A basolateral sorting signal is encoded in the α-subunit of Na-K- ATPase

Muth, T. R., Gottardi, C. J., Roush, D. L. & Caplan, M. J., Mar 1998, In : American Journal of Physiology - Cell Physiology. 274, 3 43-3, p. C688-C696

Research output: Contribution to journalArticle

38 Scopus citations

Sorting of P-type ATPases in polarized epithelial cells

Dunbar, L. A., Courtois-Coutry, N., Roush, D. L., Muth, T. R., Gottardi, C. J., Rajendran, V., Geibel, J., Kashgarian, M. & Caplan, M. J., Jan 1 1998, In : Acta Physiologica Scandinavica, Supplement. 163, 643, p. 289-295 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Tyrosine-based membrane protein sorting signals are differentially interpreted by polarized Madin-Darby canine kidney and LLC-PK1 epithelial cells

Roush, D. L., Gottardi, C. J., Naim, H. Y., Roth, M. G. & Caplan, M. J., Oct 9 1998, In : Journal of Biological Chemistry. 273, 41, p. 26862-26869 8 p.

Research output: Contribution to journalArticle

98 Scopus citations
1997

Sorting of ion pumps in polarized epithelial cells

Dunbar, L. A., Roush, D. L., Courtois-Coutry, N., Muth, T. R., Gottardi, C. J., Rajendran, V., Geibel, J., Kashgarian, M. & Caplan, M. J., 1997, In : Annals of the New York Academy of Sciences. 834, p. 514-523 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
1996
274 Scopus citations
1995

Biotinylation and assessment of membrane polarity: Caveats and methodological concerns

Gottardi, C. J., Dunbar, L. A. & Caplan, M. J., 1995, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 268, 2 37-2, p. F285-F295

Research output: Contribution to journalArticle

168 Scopus citations

Expression of a protein in rat kidney and distal colon that is related to the gastric H,K-ATPase

Okusa, M. D., Gottardi, C. J., Rajendran, V. M., Binder, H. J. & Caplan, M. J., Jan 1 1995, In : Cellular Physiology and Biochemistry. 5, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
1994

Sorting of the Gastric H,K‐ATPase in Endocrine and Epithelial Cells

Roush, D. L., Gottardi, C. J. & Caplan, M. J., Sep 1994, In : Annals of the New York Academy of Sciences. 733, 1, p. 212-222 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Synthesis and Sorting of Ion Pumps in Polarized Cells

Gottardi, C. J., Pietrini, G., Shiel, M. J. & Caplan, M. J., Jan 1 1994, In : Current topics in membranes. 41, C, p. 143-168 26 p.

Research output: Contribution to journalArticle

3 Scopus citations
1993

An ion-transporting ATPase encodes multiple apical localization signals

Gottardi, C. J. & Caplan, M. J., Apr 1993, In : Journal of Cell Biology. 121, 2, p. 283-293 11 p.

Research output: Contribution to journalArticle

115 Scopus citations

Delivery of Na+,K(+)-ATPase in polarized epithelial cells.

Gottardi, C. J. & Caplan, M. J., Apr 23 1993, In : Science. 260, 5107, p. 552-554; author reply 554-556

Research output: Contribution to journalComment/debate

Open Access
66 Scopus citations

Delivery of Na+,K+-ATPase in polarized epithelial cells

Zurzolo, C., Rodriguez-Boulan, E., Gottardi, C. J., Caplan, M. J., Siemers, K. A., Wilson, R., Mays, R. W., Ryan, T. A., Wollner, D. A. & Nelson, W. J., 1993, In : Science. 260, 5107, p. 550-556 7 p.

Research output: Contribution to journalComment/debate

37 Scopus citations

Functional properties of an H,K-ATPase/Na,K-ATPase chimera

Blostein, R., Zhang, R. P., Gottardi, C. J. & Caplan, M. J., Jan 1 1993, In : Journal of Biological Chemistry. 268, 14, p. 10654-10658 5 p.

Research output: Contribution to journalArticle

40 Scopus citations
106 Scopus citations

Sorting of ion transport proteins in polarized cells

Gottardi, C. J., Pietrini, G., Roush, D. L. & Caplan, M. J., 1993, In : Journal of cell science. 106, SUPPL. 17, p. 13-20 8 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
1992

Cell surface biotinylation in the determination of epithelial membrane polarity

Gottardi, C. J. & Caplan, M. J., Dec 1 1992, In : Journal of Tissue Culture Methods. 14, 4, p. 173-180 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
1990

The Na,K-ATPase β2 subunit is expressed in rat brain and copurifies with Na,K-ATPase activity

Shyjan, A. W., Gottardi, C. & Levenson, R., 1990, In : Journal of Biological Chemistry. 265, 9, p. 5166-5169 4 p.

Research output: Contribution to journalArticle

62 Scopus citations