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Personal profile

Research Interests

Professor Mirkin's group research focuses on developing methods for controlling the architecture of molecules and materials on the 1 – 100 nm length scale, understanding their fundamental properties, and utilizing such structures to develop novel analytical tools that can be applied in the areas of chemical and biological sensing, gene regulation, immunomodulation, lithography, catalysis, optics, and energy generation, storage, and conversion. Prof. Mirkin has pioneered the use of nanoparticle-biomolecule conjugates as synthons in materials science and the development of many nanoparticle-based extra- and intracellular biodiagnostic and therapeutic tools.

Education/Academic qualification

Organic Chemistry, PhD, Pennsylvania State University

… → 1989

BS, Dickinson College

… → 1986

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  • Project 3 – Mirkin

    Mirkin, C. A.

    National Cancer Institute


    Project: Research project

  • Research Output

    Automated Synthesis and Purification of Guanidine-Backbone Oligonucleotides

    Skakuj, K., Bujold, K. E. & Mirkin, C. A., Jun 1 2020, In : Current Protocols in Nucleic Acid Chemistry. 81, 1, e110.

    Research output: Contribution to journalArticle

  • Chain-End Functionalized Polymers for the Controlled Synthesis of Sub-2 nm Particles

    Chen, P. C., Liu, Y., Du, J. S., Meckes, B., Dravid, V. P. & Mirkin, C. A., Jan 1 2020, (Accepted/In press) In : Journal of the American Chemical Society. 0c02244.

    Research output: Contribution to journalArticle

  • Colloidal crystal engineering with metal–organic framework nanoparticles and DNA

    Wang, S., Park, S. S., Buru, C. T., Lin, H., Chen, P. C., Roth, E. W., Farha, O. K. & Mirkin, C. A., Dec 1 2020, In : Nature communications. 11, 1, 2495.

    Research output: Contribution to journalArticle

    Open Access
  • Controlling the DNA Hybridization Chain Reaction

    Figg, C. A., Winegar, P. H., Hayes, O. G. & Mirkin, C. A., May 13 2020, In : Journal of the American Chemical Society. 142, 19, p. 8596-8601 6 p.

    Research output: Contribution to journalArticle

  • Defining the Design Parameters for in Vivo Enzyme Delivery through Protein Spherical Nucleic Acids

    Kusmierz, C. D., Bujold, K. E., Callmann, C. E. & Mirkin, C. A., May 27 2020, In : ACS Central Science. 6, 5, p. 815-822 8 p.

    Research output: Contribution to journalArticle

    Open Access