Charles David James

Active

SPORE for Translational Approaches to Brain Cancer

Lesniak, M. S. (PD/PI), Lesniak, M. S. (PD/PI), Heimberger, A. B. (Co-Investigator), Heimberger, A. B. (Co-Investigator), James, C. D. (Co-Investigator) & Sonabend Worthalter, A. M. (Co-Investigator)

National Cancer Institute

8/1/23 → 7/31/28

Project: Research project

Cellular Plasticity and equilibrium in GBM Progression

Ahmed, A. U. (PD/PI), Ahmed, A. U. (PD/PI), Ben-Sahra, I. (Co-Investigator), Ben-Sahra, I. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator), Miska, J. M. (Co-Investigator), Miska, J. M. (Co-Investigator), Zhang, H. (Other) & Zhang, H. (Other)

National Institute of Neurological Disorders and Stroke

7/15/22 → 5/31/27

Project: Research project

Cysteine Depletion-induced Ferroptosis as a Therapeutic Vulnerability in Glioblastoma Temozolomide Resistance

Cheng, S.-Y. (PD/PI), Cheng, S.-Y. (PD/PI), Cheng, S.-Y. (PD/PI), Cheng, S.-Y. (PD/PI), Hu, B. (Co-Investigator), Hu, B. (Co-Investigator), Hu, B. (Co-Investigator), Hu, B. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator) & James, C. D. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

6/15/22 → 4/30/26

Project: Research project

Understanding the Behavior of Novel IL13Ralpha2-directed T cell Engager for GBM

Balyasnikova, I. V. (PD/PI), Balyasnikova, I. V. (PD/PI), Horbinski, C. M. (Co-Investigator), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator), Stupp, R. (Co-Investigator), Stupp, R. (Co-Investigator), Zhang, B. (Co-Investigator), Zhang, H. (Co-Investigator), Zhang, B. (Co-Investigator) & Zhang, H. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

4/1/21 → 3/31/26

Project: Research project

Development of B-cell-based vaccine for Glioblastoma

Lee Chang, C. (PD/PI), Lee Chang, C. (PD/PI), Balyasnikova, I. V. (Co-Investigator), Balyasnikova, I. V. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator), Miska, J. M. (Co-Investigator) & Miska, J. M. (Co-Investigator)

National Cancer Institute

3/15/21 → 2/28/26

Project: Research project

Modeling the Glioblastoma Microenvironment to Uncover Progression Mechanisms and Therapeutic Targets

Brat, D. J. (PD/PI), Brat, D. J. (PD/PI), Brat, D. J. (PD/PI), Horbinski, C. M. (Co-Investigator), Horbinski, C. M. (Co-Investigator), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator) & Mukherjee, S. (Co-Investigator)

National Cancer Institute

5/1/20 → 4/30/26

Project: Research project

Role of Protein Methylation in Cell Mitosis and Glioblastoma

Cheng, S.-Y. (PD/PI), Cheng, S.-Y. (PD/PI), Cheng, S.-Y. (PD/PI), Hu, B. (Co-Investigator), Hu, B. (Co-Investigator), Hu, B. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator) & James, C. D. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

4/15/20 → 12/31/25

Project: Research project

Finished

Targeting histone H3K4me3 for the treatment of pediatric gliomas

James, C. D. (PD/PI)

St. Baldrick's Foundation

7/1/20 → 6/30/21

Project: Research project

Development of Novel MNK Inhibitors for Treating Glioblastoma

Platanias, L. C. (PD/PI), Platanias, L. C. (PD/PI), Schiltz, G. E. (PD/PI), Schiltz, G. E. (PD/PI), Clutter, M. (Co-Investigator), Clutter, M. (Co-Investigator), Eckerdt, F. D. (Co-Investigator), Eckerdt, F. D. (Co-Investigator), Horbinski, C. M. (Co-Investigator), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator), Mishra, R. K. (Co-Investigator) & Mishra, R. K. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

9/1/19 → 6/30/24

Project: Research project

Neural Stem Cell Carriers for Glioblastoma Immunotherapy

Balyasnikova, I. V. (PD/PI), Horbinski, C. M. (Co-Investigator) & James, C. D. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

6/1/19 → 5/31/21

Project: Research project

SPORE for Translational Approaches to Brain Cancer

Lesniak, M. S. (PD/PI), Chandler, J. P. (Co-Investigator), Hu, B. (Co-Investigator), Kumthekar, P. U. (Co-Investigator), Leikin, R. G. (Co-Investigator), Liu, B. P. (Co-Investigator), Sachdev, S. (Co-Investigator), Ahmed, A. U. (Other), Balyasnikova, I. V. (Other), Bartom, E. T. (Other), Brat, D. J. (Other), Cheng, S.-Y. (Other), Horbinski, C. M. (Other), James, C. D. (Other), Lukas, R. V. (Other), Platanias, L. C. (Other), Scholtens, D. M. (Other), Stegh, A. H. (Other), Stupp, R. (Other) & Wainwright, D. A. (Other)

National Cancer Institute

8/17/18 → 7/31/23

Project: Research project

The Robert H. Lurie Comprehensive Cancer Center

Platanias, L. C. (PD/PI), Arispe, L. (Co-Investigator), Arvanitis, C. (Co-Investigator), Bonini, M. (Co-Investigator), Butt, Z. (Co-Investigator), Kocherginsky, M. (Co-Investigator), Kumthekar, P. U. (Co-Investigator), Rini, C. (Co-Investigator), Shilatifard, A. (Co-Investigator), Wignall, S. (Co-Investigator), Zhang, Z. (Co-Investigator), Agulnik, M. (Other), Awatramani, R. (Other), Backman, V. (Other), Benson III, A. B. (Other), Carthew, R. W. (Other), Cella, D. (Other), Chakravarti, D. (Other), Chandel, N. (Other), Crispino, J. D. (Other), Cristofanilli, M. (Other), Eklund, E. A. (Other), Frankfurt, O. (Other), Gordon, L. I. (Other), Green, K. J. (Other), Hahn, E. A. (Other), Hitsman, B. L. (Other), Horbinski, C. M. (Other), Horvath, C. M. (Other), Hussain, M. (Other), James, C. D. (Other), Kelleher, N. L. (Other), Khan, S. A. (Other), LaBonne, C. (Other), Larson, A. C. (Other), Matei, D. E. (Other), Meade, T. J. (Other), Mondragon, A. (Other), Mrksich, M. (Other), Munshi, H. G. (Other), Murphy, A. B. (Other), Obeng, R. (Other), Penedo, F. J. (Other), Perlman, H. R. (Other), Peter, M. E. (Other), Rademaker, A. W. (Other), Rappoport, J. Z. (Other), Rosenzweig, A. C. (Other), Scheidt, K. A. (Other), Simon, M. A. (Other), Sosman, J. A. (Other), Spring, B. (Other), Wei, J.-J. (Other), Weiss, E. L. (Other) & Woloschak, G. E. (Other)

National Cancer Institute

8/10/18 → 7/31/23

Project: Research project

Tissue Factor as a Key Determinant of IDH1 Mutant versus IDH1 Wild-type Glioma Thrombosis and Malignancy

Horbinski, C. M. (PD/PI) & James, C. D. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

7/1/17 → 6/30/22

Project: Research project

Neural Stem Cell Carriers for Glioblastoma Immunotherapy

Balyasnikova, I. V. (PD/PI), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator) & Lesniak, M. S. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

5/1/17 → 4/30/19

Project: Research project

Cellular plasticity and equilibrium in GBM progression

Ahmed, A. U. (PD/PI), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator) & Shilatifard, A. (Other)

National Institute of Neurological Disorders and Stroke

4/1/17 → 1/31/22

Project: Research project

Systemic RNA interference to reactivate p53 tumor suppression

Stegh, A. H. (PD/PI), Horbinski, C. M. (Co-Investigator) & James, C. D. (Co-Investigator)

National Cancer Institute

3/1/17 → 2/28/22

Project: Research project

CDK4/6 Inhibitor Therapy for Glioblastoma Multiforme

James, C. D. (PD/PI)

Georgetown University, National Cancer Institute

5/1/16 → 4/30/18

Project: Research project

Radiation + Temozolomide Induced Mutation and Malignant Progression of GBM

James, C. D. (PD/PI), Bi, Y. (Co-Investigator) & Davuluri, R. V. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

3/1/16 → 2/28/22

Project: Research project

Development of novel therapeutics for the treatment of human glioblastoma

Mazar, A. P. (PD/PI), James, C. D. (Co-PD/PI), Raizer, J. J. (Co-PD/PI) & Ugolkov, A. (Co-PD/PI)

Northwestern Memorial Hospital

1/1/16 → 12/31/17

Project: Research project

Molecular Characteristics and Associated Therapies for Pediatric Brainstem Glioma

James, C. D. (PD/PI)

Ann & Robert H. Lurie Children's Hospital of Chicago, John McNicholas Pediatric Brain Tumor Foundation

1/1/16 → 12/31/16

Project: Research project

Autophagy Regulation of Glioblastoma Tumorigenesis and Responses to Therapy

Cheng, S.-Y. (PD/PI), Hu, B. (Co-Investigator) & James, C. D. (Co-Investigator)

National Institute of Neurological Disorders and Stroke

9/30/15 → 6/30/21

Project: Research project

Nucleic Acid-Based Nanoconstructs for the Treatment of Cancer

Mirkin, C. A. (PD/PI), Platanias, L. C. (Co-PD/PI), Bagheri, N. (Co-Investigator), Catalona, W. J. (Co-Investigator), Espinosa, H. D. (Co-Investigator), James, C. D. (Co-Investigator), Lee, A. (Co-Investigator), Mrksich, M. (Co-Investigator), Nguyen, S. (Co-Investigator), Odom, T. W. (Co-Investigator), Stegh, A. H. (Co-Investigator), Woloschak, G. E. (Co-Investigator) & Zhang, B. (Co-Investigator)