Grants per year
Search results
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Finished
Targeting histone H3K4me3 for the treatment of pediatric gliomas
James, C. D. (PD/PI)
7/1/20 → 6/30/21
Project: Research project
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Development of Novel MNK Inhibitors for Treating Glioblastoma
Platanias, L. C. (PD/PI), Platanias, L. C. (PD/PI), Schiltz, G. E. (PD/PI), Schiltz, G. E. (PD/PI), Clutter, M. (Co-Investigator), Clutter, M. (Co-Investigator), Eckerdt, F. D. (Co-Investigator), Eckerdt, F. D. (Co-Investigator), Horbinski, C. M. (Co-Investigator), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator), James, C. D. (Co-Investigator), Mishra, R. K. (Co-Investigator) & Mishra, R. K. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
9/1/19 → 6/30/24
Project: Research project
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Neural Stem Cell Carriers for Glioblastoma Immunotherapy
Balyasnikova, I. V. (PD/PI), Horbinski, C. M. (Co-Investigator) & James, C. D. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
6/1/19 → 5/31/21
Project: Research project
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SPORE for Translational Approaches to Brain Cancer
Lesniak, M. S. (PD/PI), Chandler, J. P. (Co-Investigator), Hu, B. (Co-Investigator), Kumthekar, P. U. (Co-Investigator), Leikin, R. G. (Co-Investigator), Liu, B. P. (Co-Investigator), Sachdev, S. (Co-Investigator), Ahmed, A. U. (Other), Balyasnikova, I. V. (Other), Bartom, E. T. (Other), Brat, D. J. (Other), Cheng, S.-Y. (Other), Horbinski, C. M. (Other), James, C. D. (Other), Lukas, R. V. (Other), Platanias, L. C. (Other), Scholtens, D. M. (Other), Stegh, A. H. (Other), Stupp, R. (Other) & Wainwright, D. A. (Other)
8/17/18 → 7/31/23
Project: Research project
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The Robert H. Lurie Comprehensive Cancer Center
Platanias, L. C. (PD/PI), Arispe, L. (Co-Investigator), Arvanitis, C. (Co-Investigator), Bonini, M. (Co-Investigator), Butt, Z. (Co-Investigator), Kocherginsky, M. (Co-Investigator), Kumthekar, P. U. (Co-Investigator), Rini, C. (Co-Investigator), Shilatifard, A. (Co-Investigator), Wignall, S. (Co-Investigator), Zhang, Z. (Co-Investigator), Agulnik, M. (Other), Awatramani, R. (Other), Backman, V. (Other), Benson III, A. B. (Other), Carthew, R. W. (Other), Cella, D. (Other), Chakravarti, D. (Other), Chandel, N. (Other), Crispino, J. D. (Other), Cristofanilli, M. (Other), Eklund, E. A. (Other), Frankfurt, O. (Other), Gordon, L. I. (Other), Green, K. J. (Other), Hahn, E. A. (Other), Hitsman, B. L. (Other), Horbinski, C. M. (Other), Horvath, C. M. (Other), Hussain, M. (Other), James, C. D. (Other), Kelleher, N. L. (Other), Khan, S. A. (Other), LaBonne, C. (Other), Larson, A. C. (Other), Matei, D. E. (Other), Meade, T. J. (Other), Mondragon, A. (Other), Mrksich, M. (Other), Munshi, H. G. (Other), Murphy, A. B. (Other), Obeng, R. (Other), Penedo, F. J. (Other), Perlman, H. R. (Other), Peter, M. E. (Other), Rademaker, A. W. (Other), Rappoport, J. Z. (Other), Rosenzweig, A. C. (Other), Scheidt, K. A. (Other), Simon, M. A. (Other), Sosman, J. A. (Other), Spring, B. (Other), Wei, J.-J. (Other), Weiss, E. L. (Other) & Woloschak, G. E. (Other)
8/10/18 → 7/31/23
Project: Research project
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Tissue Factor as a Key Determinant of IDH1 Mutant versus IDH1 Wild-type Glioma Thrombosis and Malignancy
Horbinski, C. M. (PD/PI) & James, C. D. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
7/1/17 → 6/30/22
Project: Research project
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Neural Stem Cell Carriers for Glioblastoma Immunotherapy
Balyasnikova, I. V. (PD/PI), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator) & Lesniak, M. S. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
5/1/17 → 4/30/19
Project: Research project
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Cellular plasticity and equilibrium in GBM progression
Ahmed, A. U. (PD/PI), Horbinski, C. M. (Co-Investigator), James, C. D. (Co-Investigator) & Shilatifard, A. (Other)
National Institute of Neurological Disorders and Stroke
4/1/17 → 1/31/22
Project: Research project
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Systemic RNA interference to reactivate p53 tumor suppression
Stegh, A. H. (PD/PI), Horbinski, C. M. (Co-Investigator) & James, C. D. (Co-Investigator)
3/1/17 → 2/28/22
Project: Research project
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CDK4/6 Inhibitor Therapy for Glioblastoma Multiforme
James, C. D. (PD/PI)
Georgetown University, National Cancer Institute
5/1/16 → 4/30/18
Project: Research project
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Radiation + Temozolomide Induced Mutation and Malignant Progression of GBM
James, C. D. (PD/PI), Bi, Y. (Co-Investigator) & Davuluri, R. V. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
3/1/16 → 2/28/22
Project: Research project
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Molecular Characteristics and Associated Therapies for Pediatric Brainstem Glioma
James, C. D. (PD/PI)
Ann & Robert H. Lurie Children's Hospital of Chicago, John McNicholas Pediatric Brain Tumor Foundation
1/1/16 → 12/31/16
Project: Research project
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Development of novel therapeutics for the treatment of human glioblastoma
Mazar, A. P. (PD/PI), James, C. D. (Co-PD/PI), Raizer, J. J. (Co-PD/PI) & Ugolkov, A. (Co-PD/PI)
Northwestern Memorial Hospital
1/1/16 → 12/31/17
Project: Research project
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Autophagy Regulation of Glioblastoma Tumorigenesis and Responses to Therapy
Cheng, S.-Y. (PD/PI), Hu, B. (Co-Investigator) & James, C. D. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
9/30/15 → 6/30/21
Project: Research project
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Nucleic Acid-Based Nanoconstructs for the Treatment of Cancer
Mirkin, C. A. (PD/PI), Platanias, L. C. (Co-PD/PI), Bagheri, N. (Co-Investigator), Catalona, W. J. (Co-Investigator), Espinosa, H. D. (Co-Investigator), James, C. D. (Co-Investigator), Lee, A. (Co-Investigator), Mrksich, M. (Co-Investigator), Nguyen, S. (Co-Investigator), Odom, T. W. (Co-Investigator), Stegh, A. H. (Co-Investigator), Woloschak, G. E. (Co-Investigator) & Zhang, B. (Co-Investigator)
9/1/15 → 7/31/21
Project: Research project
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CCNE Project #2: Spherical Nucleic Acids for Metabolic Reprogramming of Malignant Glioma
James, C. D. (PD/PI) & James, C. D. (Subproject PI)
9/1/15 → 7/31/21
Project: Research project
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Glioblastoma Phenotype Modulation Through miRNA Control of Wnt Signaling
Cheng, S.-Y. (PD/PI), Hu, B. (Co-Investigator) & James, C. D. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
9/1/15 → 5/31/21
Project: Research project
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Assessing the Potency of (Company's Proprietary Compound) on Orthotopic Patient Derived Glioblastoma Tumors
James, C. D. (PD/PI) & Raizer, J. J. (Co-Investigator)
Upsher-Smith Laboratories, Inc.
4/9/15 → 4/8/16
Project: Research project
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The Role of Cidofovir and Structural Analogs as Adjuvant Therapy for Glioblastoma
James, C. D. (PD/PI)
Swedish Medical Center, National Cancer Institute
9/4/14 → 8/31/18
Project: Research project
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BRAF Mutation in Malignant Astrocytoma Origin, Evolution, and Response to Therapy
James, C. D. (PD/PI)
National Institute of Neurological Disorders and Stroke
9/1/14 → 8/31/18
Project: Research project
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Targeting the Histone H3.3-K27M Mutation for the Treatment of Diffuse Intrinsic Pontine Gliomas
Hashizume, R. (PD/PI) & James, C. D. (Co-Investigator)
Matthew Larson Foundation for Pediatric Brain Tumors
8/1/14 → 4/30/16
Project: Research project
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Targeting Histone H3.3-K27M Mutation for the Treatment of DIPGs
Hashizume, R. (PD/PI) & James, C. D. (Co-Investigator)
Bear Necessities Pediatric Cancer Foundation
7/1/14 → 6/30/15
Project: Research project
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Role of mTORC2 in GBM - Development of a Novel Therapeutic mTOR Kinase Inhibitor
James, C. D. (PD/PI)
Ludwig Institute for Cancer Research, National Institute of Neurological Disorders and Stroke
6/1/14 → 5/31/16
Project: Research project
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CDK4/6 Inhibitor Therapy for Glioblastoma Multiforme
James, C. D. (PD/PI)
Georgetown University, National Cancer Institute
5/1/14 → 4/30/16
Project: Research project